Selank peptide(selanc) yog hmoov dawb. Cov khoom xyaw tseem ceeb yog selanc, uas yog cov roj tswj kev noj qab haus huv thiab kev noj qab haus huv cov zaub mov raws li casein complex peptides thiab ntxiv nrog cov tshuaj uas muaj linolenic acid thiab linoleic acid; Peb lub tuam txhab muaj pentide selanc muag thiab tseem muaj selanc hmoov. Yog tias koj xav yuav selanc online, thov xa email rau peb. Cov khoom no muaj kev soj ntsuam zoo hauv kev tiv thaiv kab mob plawv thiab paj hlwb, bi- kev tswj hwm ntawm cov ntshav siab, tswj cov ntshav lipids, cholesterol, inhibiting thrombotic hlwb kab mob, tiv thaiv - qog, inhibiting kev tsis haum tshuaj, txhim kho kev tiv thaiv, txhim kho kev txawj ntse thiab kev pom, thiab lwm yam.
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Tshuaj Formula |
C33H57N11O9 |
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Exact Mass |
751.43 |
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Molecular Luj |
751.89 |
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m/z |
751.43 (100.0%), 752.44 (35.7%), 753.44 (3.5%), 753.44 (2.7%), 752.43 (2.2%), 753.44 (1.8%), 752.43 (1.8%) |
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Elemental Analysis |
C, 52.72; H, 7.64; N, 20.49; O, 19.15 |
Customized Bottle Caps & Corks
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Kev ntxhov siab thiab tshuaj tiv thaiv kev ntxhov siab
Cov teebmeem neuromodulatory ntawmSelank peptideua rau nws yog ib qho tseem ceeb heev anxiolytic thiab antidepressant tshuaj. Cov tshuaj no txo qis qhov pib ntawm kev ntxhov siab thiab kev nyuaj siab los ntawm kev txo qis ntawm gamma-aminobutyric acid (GABA) thiab txhawb kev tsim cov neurons. Qhov no tuaj yeem pab tau zoo rau cov neeg uas tsis xis nyob hauv kev sib raug zoo lossis xav tias ntxhov siab thiab tsis nyob hauv lawv lub neej txhua hnub.
Txhim kho kev nco thiab kev muaj peev xwm kawm
Selanc tuaj yeem txhim kho kev nco thiab kev kawm los ntawm kev nce qib ntawm cov neurotransmitter acetylcholine hauv lub hlwb. Txij li thaum acetylcholine yog ib qho tseem ceeb tshaj plaws neurotransmitters nyob rau hauv tib neeg lub hlwb, selanc tuaj yeem pab tib neeg txhim kho lub sijhawm ntev - lub sij hawm thiab luv luv - lub sij hawm nco thiab ua kom ceev cov txheej txheem thiab khaws cov ntaub ntawv los ntawm kev nce nws cov ntsiab lus.
Txhim kho kev tiv thaiv
Selank kuj tau pom tias ua haujlwm hauv kev txhawb nqa lub cev tiv thaiv kab mob los ntawm ntau lub tshuab. Qee cov kev tshawb fawb tau pom tias selanc tuaj yeem txhawb nqa tib neeg lub cev tiv thaiv kab mob los tsim cov qe ntshav dawb, tshuaj tiv thaiv kab mob thiab cytokines, thiab lwm yam, thiab txhim kho lub cev tiv thaiv kab mob. Tsis tas li ntawd, nws txo qhov mob thiab oxidative kev nyuaj siab, uas tuaj yeem pab txo cov tsos mob tshwm sim los ntawm qee yam kab mob autoimmune.
Selank yog polypeptide compound uas nws cov khoom muaj zog zoo ib yam li lwm cov polypeptides, feem ntau muaj kev cuam tshuam ntawm nws pawg thiab kev cuam tshuam nrog lwm cov molecules. Nyob rau hauv tus txheej txheem ntawm kev tshawb fawb thiab siv selanc, nws yog ib qho tseem ceeb heev kom nkag siab txog nws cov reactivity.
Selanc muaj 7 amino acid residues, 5 ntawm uas yog fatty amide pawg, 1 yog glycine thiab 1 yog alanine. Cov hydrogen thiab oxygen atoms nyob rau hauv cov residues tuaj yeem tsim kev sib cuam tshuam los ntawm hydrogen bonds, yog li tswj cov qauv spatial thiab stability ntawm polypeptide.
Nyob rau hauv selanc, acidic los yog yooj yim amino thiab carboxyl pawg tuaj yeem tsim kev cuam tshuam nrog hydrogen bonds hauv lwm cov amino acid residue. Piv txwv li, thaum cov amino pawg ntawm glycine residues tsim hydrogen bonds nrog cov amino pawg ntawm alanine residues, cov qauv spatial ntawm selanc hloov, uas yuav ua rau muaj kev hloov hauv nws cov tshuaj pharmacological.
Lub molecule ntawm selanc muaj ntau carboxyl thiab amino pawg, uas yog yooj yim oxidized nyob rau hauv tej yam kev mob. Piv txwv li, nyob rau hauv lub xub ntiag ntawm oxygen, pawg carboxyl ntawm selanc tuaj yeem oxidized rau carboxylic acid, yog li hloov nws cov qauv spatial thiab pharmacological teebmeem.
Tsis tas li ntawd, sulfur oxides hauv selanc molecules kuj tuaj yeem raug oxidation tshwm sim. Nyob rau hauv lub xub ntiag ntawm oxygen, nws yuav ua rau sulfation thiab lwm yam alkylation tshuaj, yog li cuam tshuam rau nws pharmacological teebmeem.
Selank yog polypeptide uas yooj yim zom los ntawm cov enzymes xws li proteolytic enzymes. Cov enzymes no tuaj yeem hydrolyze cov peptide bonds hauv selanc, yog li rhuav tshem nws mus rau hauv me me polypeptides lossis amino acid residues.
Hauv tib neeg lub cev, selanc feem ntau tawg los ntawm cov enzymes proteolytic hauv plab hnyuv. Yog li, cov tshuaj pharmacological ntawm selanc tuaj yeem cuam tshuam los ntawm kev zom zaub mov hauv qhov ncauj lossis kev txhaj tshuaj.
Lub molecule ntawm selanc muaj ntau yam amino acid residues, thiab condensation tshwm sim tuaj yeem tshwm sim ntawm cov residues. Piv txwv li, nyob rau hauv acidic los yog yooj yim tej yam kev mob, ib tug phosphite daim ntawv cog lus yuav tsim ntawm ib tug glycine residue thiab alanine residue, yog li tsim ib tug loj polypeptide molecule.
Qhov tshwm sim ntawm cov tshuaj tiv thaiv condensation feem ntau xav tau qee yam mob, xws li acidic lossis alkaline ib puag ncig, kub kub thiab lwm yam. Yog li ntawd, nyob rau hauv lub chaw soj nstuam thiab daim ntawv thov, nws yog feem ntau tsim nyog los tswj cov kev mob thiab qhov npaum li cas ntawm cov condensation cov tshuaj tiv thaiv los xyuas kom meej qhov zoo thiab kev ua tau zoo ntawm cov khoom tau txais.
Ntxiv nrog rau cov tshuaj tiv thaiv saum toj no, selanc kuj tuaj yeem cuam tshuam nrog ntau yam ntawm lwm cov molecules. Piv txwv li, selanc tuaj yeem tsim kev sib koom ua ke nrog cov hlau ions, yog li cuam tshuam rau nws cov tshuaj pharmacological. Tsis tas li ntawd, selanc tuaj yeem cuam tshuam nrog lwm cov proteins los hloov lawv txoj haujlwm thiab cov qauv spatial.
Zuag qhia tag nrho, cov tshuaj tiv thaiv ntawm selanc zoo ib yam li lwm cov peptides, suav nrog hydrogen daim ntawv cog lus, cov tshuaj tiv thaiv oxidation, kev zom zaub mov, cov tshuaj tiv thaiv condensation, thiab cov tshuaj tiv thaiv nrog lwm cov molecules. Thaum ua ntawv thov thiab tshawb fawb selanc, nws yog ib qho tsim nyog yuav tau xav txog cov kev cuam tshuam no thiab lawv cov teebmeem, thiab kho cov kev mob tshwm sim thiab cov txheej txheem kom tsim nyog los xyuas kom meej nws cov tshuaj pharmacological thiab zoo.
Selank peptide, tseem hu ua selanc, yog ib qho hluavtaws tetrapeptide muab tau los ntawm lub ntuj amino acid ib ntus pom hauv tib neeg lub cev. Nws yog nyob rau hauv ib chav kawm ntawm cov tebchaw hu ua immunopeptides lossis nootropic peptides, uas yog tsim los ua kom muaj kev cuam tshuam zoo rau kev txawj ntse thiab kev xav zoo- yog. Selanc tau tsim nyob rau hauv Russia los ntawm lub koom haum ntawm Molecular Genetics ntawm Lavxias teb sab Academy ntawm Sciences raws li ib tug muaj peev xwm kho tus neeg sawv cev rau kev kho mob ntawm kev ntxhov siab vim thiab kev ntxhov siab - cuam tshuam cov kab mob.
Cov qauv tshuaj ntawm selanc muaj plaub amino acids: L-glutamic acid, L-tryptophan, L-glycine, thiab glycine ethyl ester. Qhov kev sib xyaw tshwj xeeb ntawm cov amino acids no ntseeg tau tias muaj kev cuam tshuam nrog lub hauv nruab nrab lub paj hlwb, tshwj xeeb tshaj yog cov serotonergic thiab glutamatergic systems, uas koom nrog hauv kev tswj kev xav, kev ntxhov siab, thiab kev ntxhov siab.
Lub luag haujlwm tseem ceeb ntawm kev ua ntawm selanc yog xav tias yog nws lub peev xwm los hloov kho cov qib neurotransmitter hauv lub hlwb, tshwj xeeb yog serotonin thiab glutamate. Los ntawm kev cuam tshuam cov neurotransmitters, selanc tuaj yeem pab kho qhov sib npaug hauv lub hlwb cov tshuaj ib puag ncig, yog li txo cov tsos mob ntawm kev ntxhov siab thiab kev ntxhov siab.
Tsis zoo li cov tshuaj anxiolytics, selanc tsis yog ib qho sedative lossis ntxiv, thiab nws tau tshaj tawm tias muaj kev hloov maj mam thiab sib npaug ntawm lub cev. Cov kev tshawb fawb soj ntsuam tau pom tias selanc tuaj yeem txo qis kev ntxhov siab, txhim kho kev txawj ntse hauv kev ntxhov siab, thiab txhim kho tag nrho lub siab lub ntsws thiab ua kom muaj zog.
Tsis tas li ntawd, selanc tau kawm txog nws lub peev xwm los txhim kho kev pw tsaug zog zoo, nco, thiab ua kom pom tseeb, ua rau nws yog qhov kev xaiv zoo nkauj rau cov tib neeg uas nrhiav lub ntuj thiab tsis yog - cwj pwm - ua txoj hauv kev los tswj kev ntxhov siab thiab kev ntxhov siab.
Hauv cov ntsiab lus, nws yog ib qho hluavtaws tetrapeptide tsim los txo kev ntxhov siab thiab kev ntxhov siab- cov tsos mob ntsig txog los ntawm kev hloov pauv cov qib neurotransmitter hauv lub hlwb. Nws cov txheej txheem tshwj xeeb ntawm kev ua thiab tsis yog- qhov xwm txheej ua rau nws muaj kev cog lus kho mob rau cov neeg nrhiav lwm txoj kev kho mob rau kev ntxhov siab thiab tswj kev ntxhov siab.
Cov lus nug nquag
Cov txiaj ntsig ntawm Selank yog dab tsi?
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Selank los ntawm nws tus kheej ib txwm tau muab tshuaj rau kev ntxhov siab thiab kev nyuaj siab. Selank tau tshaj tawm cov haujlwm anxiolytic thiabua raws li kev ruaj ntseg neuropsychotropic, antidepressant, thiab tshuaj tiv thaiv- kev ntxhov siab. Semax yog siv los ua kev kho mob rau cov neeg mob uas muaj cov kab mob pathologies cuam tshuam rau lub hlwb kev ua haujlwm tsis zoo.
Selank puas muaj kev phiv tshuaj?
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Cov kev tshawb fawb soj ntsuam tau pom tias cov nyhuv ntawm Selank zoo ib yam li cov tshuaj tranquilizers ntawm cov koob tshuaj tsawg, tab sis tsis tau nrog cov kev mob tshwm sim ntawm benzodiazepine tranquilizers xws li amnesia, tshem tawm, thiab dependence (Seredenin li al., 1990, 1998).
Koj tuaj yeem noj Selank txhua hnub?
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Injectable Selank ib txwm muaj cov txheej txheem noj tshuaj ntawm tsib hnub hauv ib lub lis piam, qhov sib txawv ntawm intranasal yuav xav tau ib zaug - lossis ob zaug - kev tswj hwm txhua hnub.Cov koob tshuaj tuaj yeem noj txhua lub sijhawm ntawm hnub, tab sis thaum sawv ntxov kev tswj hwm yuav tso cai rau tus neeg siv kom tau txais txiaj ntsig zoo dua ntawm Selank cov txiaj ntsig nootropic.
Dab tsi yog qhov txawv ntawm Semax thiab selanc?
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Cov kab hauv qab: Xaiv Semax yog tias lub hom phiaj yog kev txawj ntse dua, kev tiv thaiv kab mob, lossis tom qab - rov qab mob stroke. Xaiv Selank yog tias lub hom phiaj tswj kev ntxhov siab, ntxhov siab, lossis ua kom lub siab nyob ruaj khov yam tsis muaj lub hnab ntim khoom sedative.
Selanc ua dab tsi rau lub hlwb?
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Selanktxhawb kev noj qab haus huv neuronal thiab plasticitylos ntawm: Kev nce nrawm ntawm lub hlwb- tau txais txiaj ntsig neurotrophic (BDNF) qhia hauv hippocampus. Txhim kho ntawm synaptic plasticity thiab neuronal ciaj sia taus. Kev tiv thaiv kev ntxhov siab- ua rau muaj kev puas tsuaj neuronal.
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