Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm snap 8 hmoov hauv Suav teb. Txais tos rau kev lag luam wholesale bulk zoo snap 8 hmoov muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
SNAP 8 Powder(Acetyl Octapeptide-3 Powder) yog peptide hluavtaws uas muaj yim amino acids, feem ntau yog siv los tiv thaiv- kev laus ntawm daim tawv nqaij. Nws txo qhov tsim ntawm dynamic wrinkles los ntawm inhibiting lub ntsej muag nqaij contraction. Nws cov xwm txheej khaws cia yuav tsum tau xaiv ntawm 2-8℃lossis -20℃raws li kev siv scenario kom muaj kev ruaj ntseg. Nws feem ntau yog nyob rau hauv daim ntawv ntawm cov hmoov dawb, tab sis kuj muaj nyob rau hauv cov kua daim ntawv. Nws simulates N-terminal kawg ntawm SNAP-25 thiab sib tw rau qhov chaw ntawm SNAP-25 hauv fusion vesicle complex, yog li cuam tshuam nrog kev tsim ntawm fusion vesicle complex. Qhov kev cuam tshuam no ua rau qhov tsis muaj peev xwm ntawm cov hlwv kom tso tawm cov neurotransmitters zoo, yog li ua rau cov leeg tsis muaj zog thiab tiv thaiv kev tsim ntawm wrinkles. Tshwj xeeb tshaj yog rau wrinkles tshwm sim los ntawm lub ntsej muag qhia cov leeg nqaij contraction, xws li wrinkles nyob ib ncig ntawm lub hauv pliaj thiab ob lub qhov muag, nws muaj ib tug tseem ceeb txo cov nyhuv.
Nyob rau tib lub sijhawm, peb lub tuam txhab tsis yog tsuas yog muab cov hmoov ntshiab, tab sis kuj muaj cov ntsiav tshuaj thiab tshuaj txhaj. Yog tias xav tau, thov koj xav tiv tauj peb txhua lub sijhawm.
Peb cov khoom
| Khoom npe | SNAP 8 Powder | SNAP 8 Txhaj | SNAP 8 Solution | SNAP 8 Cream |
| Yam khoom | Hmoov | ua kua | ua kua | tshuaj pleev ib ce |
| Khoom Purity | Ntau dua lossis sib npaug li 99% | Ntau dua lossis sib npaug li 99% | Ntau dua lossis sib npaug li 99% | Ntau dua lossis sib npaug li 99% |
| Khoom Specifications | 100g / 1kg / thiab lwm yam. | 5 mg/10 mg/20 mg/30 mg | 15ml / 20ml / 30ml | 2 mg/5 mg/10 mg |
| Daim ntawv khoom | Organic synthesis | Organic synthesis | Kev thov sab nraud | Kev thov sab nraud |
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SNAP 8 COA
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| Certificate of Analysis | ||
| Compound npe | NPE-8 | |
| Qib | Pharmaceutical qib | |
| CAS Nr. | 1253115-75-1 | |
| Ntau | 25g | |
| Ntim txheem | PE hnab + Al foil hnab | |
| Chaw tsim tshuaj paus | Shaanxi BLOOM TECH Co., Ltd | |
| Ntau No. | 202512090051 | |
| MFG | Peb 9, 2025 | |
| EXP | Peb 8 Dec 2028 | |
| Qauv | N/A | |
| Yam khoom | Enterprise txheem | Kev txheeb xyuas qhov tshwm sim |
| Qhov tshwm sim | Dawb los yog yuav luag dawb hmoov | Ua raws |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 5.0% | 0.38% |
| Poob rau ziab | Tsawg dua lossis sib npaug li 1.0% | 0.28% |
| Hnyav Hlau | Pb Tsawg dua lossis sib npaug li 0.5ppm | N.D. |
| Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Hg Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Cd Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Purity (HPLC) | Ntau dua lossis sib npaug li 99.0% | 99.80% |
| Ib leeg impurity | <0.8% | 0.47% |
| Tag nrho microbial suav | Tsawg dua lossis sib npaug li 750cfu / g | 70 |
| E. Coli | Tsawg dua lossis sib npaug li 2MPN / g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (los ntawm GC) | Tsawg dua lossis sib npaug li 5000ppm | 400ppm ua |
| Cia | Khaws rau hauv qhov chaw kaw, tsaus, thiab qhuav hauv qab 2-8 degree | |
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Hauv thaj tsam ntawm kev tiv thaiv- kev laus ntawm daim tawv nqaij,SNAP 8 Powder(Acetyl Octapeptide-3) tab tom ua rau muaj kev hloov pauv nrog daim ntawv lo ntawm "tsis muaj tshuaj botulinum toxin hloov pauv". Raws li ib tug hluavtaws peptide tsim raws li niaj hnub biochemical mechanisms, nws cov nqi tseem ceeb nyob rau hauv txo cov tsim ntawm dynamic wrinkles ntawm lub hauv paus los ntawm inhibiting lub ntsej muag nqaij contraction. Piv nrog rau cov khoom xyaw tshuaj tiv thaiv wrinkle, SNAP 8 tau dhau los ua "lub hnub qub muaj khoom" hauv cov khoom siv tawv nqaij siab - kawg vim nws tsis yog - ntxeem tau, muaj kev nyab xeeb siab, thiab muaj ntau yam kev ua tau zoo.
Mechanism ntawm kev txiav txim: Kev tshawb fawb saw los ntawm neural signals mus rau cov leeg so
Kev rov ua dua ntawm cov leeg ntawm lub ntsej muag yog qhov ua rau muaj qhov tsis zoo ntawm cov tawv nqaij xws li cov quav ko taw, hauv pliaj wrinkles, thiab nasolabial folds. Thaum cov hlab ntsha xaus tso tawm acetylcholine (ACh), nicotinic acetylcholine receptor (nAChR) ntawm cov leeg cell membrane yog qhib, ua rau calcium influx thiab nqaij contraction. Lub sij hawm ntev tsis tu ncua tuaj yeem ua rau collagen tawg, elastic fiber ntau degradation, thiab thaum kawg irreversible static wrinkles.
SNAP 8 sib tw khi rau lub subunit ntawm nAChR los ntawm kev simulating N-terminal qauv ntawm ACh, yog li thaiv kev khi ntawm ACh mus rau receptor.Cov txheej txheem no tsis tas yuav nkag mus rau sab hauv ntawm tes, tsuas yog yuav tsum tau ua kom muaj kev cuam tshuam rau ntawm lub cell membrane, uas tuaj yeem txo qis kev sib cog lus ntawm cov leeg nqaij thiab cov calcium. Kev sim cov ntaub ntawv qhia tau hais tias 10% concentration ntawm SNAP 8 daws tuaj yeem txo cov leeg nqaij amplitude los ntawm 30% -50%, thiab cov nyhuv tuaj yeem kav ntev li 8-12 teev.
Multi-dimensional teebmeem los ntawm wrinkle tsis kam rau kho daim tawv nqaij
Targeted kho rau dynamic wrinkles muaj feem xyuam rau lub hauv pliaj (pem hauv pliaj wrinkles), qhov muag cheeb tsam (crow's taw), lub hauv pliaj (nasolabial folds), thiab nasolabial folds (nasolabial folds). Los ntawm kev thov hauv zos ob zaug hauv ib hnub (tag kis sawv ntxov thiab yav tsaus ntuj), SNAP 8 tuaj yeem nkag mus rau hauv qab ntawm stratum corneum thiab tsis tu ncua cuam tshuam cov leeg ntawm lub ntsej muag. Kev siv sijhawm ntev (8-12 lub lis piam) tuaj yeem txo qhov tob thiab ntev ntawm wrinkles. Kev soj ntsuam kuaj pom tau tias 3% kev daws teeb meem tuaj yeem txo qhov ntim ntawm wrinkles ib ncig ntawm lub qhov muag los ntawm 21%.
Qhov tsim ntawm static wrinkles yog ze ze rau qhov poob ntawm collagen. SNAP 8 tuaj yeem txo qhov kev ntxhov siab ntawm cov tawv nqaij thiab ua kom cov collagen degradation qeeb los ntawm kev txo cov leeg nqaij ntau dhau. In addition, the acetyl group in its molecular structure has hydrophilicity and can assist in locking in skin moisture, increasing the moisture content of the stratum corneum to 15% -20%, indirectly enhancing skin elasticity.
Multi-dimensional teebmeem los ntawm wrinkle tsis kam rau kho daim tawv nqaij
SNAP 8 tuaj yeem txhawb nqa keratinocytes kom zais cov tshuaj tiv thaiv kab mob peptides (xws li beta blockers), txhim kho daim tawv nqaij tiv thaiv kab mob. Lub caij no, nws txoj haujlwm ntawm kev tswj hwm keratinocyte sib txawv pab kho cov teeb meem puas thiab txo cov dej tsis zoo (TEWL). Rau cov tib neeg uas muaj cov tawv nqaij rhiab los yog teeb meem kev puas tsuaj, SNAP 8 kev daws teeb meem ntawm 0.5% -1% tuaj yeem txo cov tawv nqaij erythema Performance index (EI) thiab stinging hnov.
SNAP 8 feem ntau yog siv ua ke nrog cov khoom xyaw hauv qab no kom ua tiav qhov ua tau zoo tshaj plaws:
Palmitoyl Pentapeptide-4: nkoos collagen synthesis thiab puv static wrinkles.
GHK Cu: Txhawb kev kho qhov txhab thiab kho UV puas.
Hyaluronic acid: txhim khu cov khoom moisturizing thiab txhim kho peptide kev ua haujlwm ntawm kev nkag mus.
Vitamin C derivatives: antioxidant thiab tiv thaiv kev yees duab.
Kev Siv: Ib Daim Ntawv Qhia Txog Kev Ua Haujlwm los ntawm Chav Saib Xyuas Kev Kho Mob Txhua Hnub
Kev sib xyaw ua ke rau cov hmoov ntshiab
SNAP 8 hmoovyuav tsum tau tov nrog dej- raws li cov neeg nqa khoom (xws li dej deionized thiab hyaluronic acid gel) ua ntej siv. Cov kauj ruam xa mus yog raws li nram no:
Qhov hnyav
Xam cov hmoov hmoov uas yuav tsum tau ua raws li lub hom phiaj concentration (feem ntau yog 3% -10%) (xws li . 1g hmoov+9ml carrier=10% tov).
Dissolve
Maj mam ntxiv cov hmoov rau cov cab kuj thiab do kom txog thaum pob tshab tag (kom tsis txhob clumping).
Cia
Ntim rau hauv ib lub thawv tsaus thiab khaws cia rau hauv lub tub yees ntawm 4℃rau kwv yees li 3 lub hlis.
Kev sib xyaw ua ke hauv kev tu tawv nqaij txhua hnub
Essence daws
Sib tov cov tshuaj npaj SNAP 8 (5% -10%) nrog vitamin C essence, thiab siv nws tom qab ntxuav thaum sawv ntxov thiab yav tsaus ntuj.
Daim npog ntsej muag
Ntxiv 2-3ml SNAP 8 daws rau lub ntsej muag tsis-woven, siv rau ntawm lub ntsej muag rau 15 feeb, thiab tshem tawm.
Qhov muag cream
Ntxiv 0.5% SNAP 8 hmoov ncaj qha mus rau cov khoom muag muag muag, do sib npaug ua ntej siv.
Concentration xaiv thiab kev npaj lub voj voog
| Concentration Range | Muaj pes tsawg leeg | Kev siv lub voj voog | Txim Txim |
| 0.5%-1% | Cov nqaij ntshiv / kev tiv thaiv | Ntev - siv sijhawm | Ua kom tawv nqaij elasticity thiab txo cov kab zoo |
| 3%-5% | Me me mus rau nruab nrab dynamic wrinkles | 8-12 lub lis piam | Wrinkle qhov tob txo los ntawm 20% -30% |
| 8%-10% | Cov tawv nqaij tawv heev / qib kws kho mob | 4-6 lub lis piam (yuav tsum muaj kev koom tes) | Txhim kho cov qauv ntsej muag zoo heev |
Attention: High concentrations (>10%) tuaj yeem ua rau mob ib ntus lossis erythema. Nws raug nquahu kom pib nrog 3% rau thawj zaug siv thiab maj mam tsim kev kam rau siab.
Kev sib piv zoo nrog botulinum toxin
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Feature |
NPE 8 | Botox tshuaj |
| Hom kev ua | Daim ntawv thov tshuaj, thaiv cov paj hlwb | Txhaj rau cov leeg kom tuag tes tuag taw cov hlab ntsha |
| Lub sijhawm pib | 2-4 lub lis piam (yuav tsum tau siv txuas ntxiv) | 3-7 hnub (tom qab txhaj tshuaj) |
| Lub sijhawm tu | 8-12 teev/lub sij hawm, sau ntau tshaj kev siv mus sij hawm ntev | 3-6 lub hlis / sijhawm |
| Kev nyab xeeb | Tsis tshua muaj irritability, tsis muaj kev pheej hmoo | Tej zaum yuav ua rau lub ntsej muag tawv, ua xua, thiab lwm yam |
| Kev siv scenarios | Kev tu tawv nqaij txhua hnub, tuaj yeem kho tus kheej | Cov kws kho mob tshwj xeeb yuav tsum tau ua haujlwm |
kev phiv tshuaj
SNAP 8 Powder(Acetyl Octapeptide-3), raws li ib qho kev txhaj tshuaj tsis zoo rau botulinum toxin, tuav txoj haujlwm tseem ceeb hauv kev tiv thaiv kev laus ntawm daim tawv nqaij vim nws muaj peev xwm tiv thaiv cov leeg nqaij thiab txo qis wrinkles. Txawm li cas los xij, txhua yam khoom muaj txiaj ntsig muaj peev xwm ua rau muaj kev cuam tshuam tsis zoo.
Local stimulus teb
Cov pob liab liab thiab khaus khaus
Mechanism of occurrence: High concentration (>10%) lossis qis purity SNAP 8 tuaj yeem cuam tshuam rau daim tawv nqaij barrier, qhib TRPV1 (transient receptor tej zaum vanillic acid subtype 1) raws, thiab ua rau cov kab mob neurogenic.
Cov yam tseem ceeb: Cov tawv nqaij puas tsuaj (xws li cov tawv nqaij rhiab heev thiab cov neeg mob eczema), kev sib koom ua ke ntawm cov khoom xyaw ua kom khaus (xws li cawv thiab txiv hmab txiv ntoo acid) hauv cov mis, thiab tsis muaj kev kuaj tawv nqaij.
Stinging Sensation
Mechanism ntawm qhov tshwm sim: Thaum peptide molecules nkag mus rau hauv qab ntawm stratum corneum, lawv tuaj yeem txhawb nqa keratinocytes tso tawm ATP, qhib P2X4 receptors, thiab ua rau muaj kev cuam tshuam cov teeb liab.
Data support: In vitro experiments have shown that SNAP 8 can significantly increase the ATP release of keratinocytes at concentrations>5% (p<0.05).
Lub tswv yim txo qis: Txo cov kev siv zog (pom zoo pib los ntawm 0.5% ~ 1%), ua ke nrog cov khoom xyaw soothing (xws li panthenol thiab bisabolol), thiab tsis txhob siv cov khoom siv acidic.
Kev tsis haum tshuaj & Cov tshuaj tiv thaiv kab mob tsis zoo
Tiv tauj dermatitis
Mechanism ntawm qhov tshwm sim: impurities nyob rau hauv SNAP 8, xws li unacetylated octapeptides, tej zaum yuav ua raws li haptens thiab khi rau daim tawv nqaij proteins los ua tiav antigens, ua rau IgE mediated type I hypersensitivity tshua.
Clinical manifestations: Mob theem: erythema, edema, hlwv; Lub sijhawm ntev: Moss zoo li hloov pauv, pigmentation; Diagnostic method: Patch test (siv 0.1% SNAP 8 tov rau sab hauv sab caj npab, saib cov tshuaj tiv thaiv tom qab 48 teev).
Kev tswj tsis zoo ntawm lub paj hlwb & kev cuam tshuam metabolic
SNAP 8 tuaj yeem nkag mus rau hauv cov hlab ntsha los ntawm daim tawv nqaij, cuam tshuam rau nAChR kev ua haujlwm ntawm lub hauv nruab nrab paj hlwb.
Tsiaj sim: Tom qab kev tswj hwm qhov ncauj ntawm SNAP 8 (500mg / kg) rau nas, muaj kev ua haujlwm luv luv thiab txo qis hauv lub cev kub, tab sis tsis ntev - lub sij hawm neurotoxicity tau pom.
Risk assumption: Cov koob tshuaj ntau ntawm SNAP 8 tuaj yeem cuam tshuam kev ua haujlwm ntawm acetylcholinesterase (AChE), ua rau ACh tsub zuj zuj.
Supporting evidence: In vitro experiments have shown that SNAP 8 can slightly inhibit AChE activity at concentrations>1mM (inhibition tus nqi<10%).
Qhov tseem ceeb ntawm kev siv: Qhov siab ntawm SNAP 8 hauv kev tu tawv nqaij txhua hnub (feem ntau<10%) is much lower than the inhibition threshold, indicating extremely low risk.
Discovery Background
Los ntawm lub xyoo pua 20th mus rau thaum ntxov xyoo pua 21st, cov tshuaj tiv thaiv -wrinkle kev ua tau zoo ntawm botulinum toxin tau raug pov thawj. Txawm li cas los xij, vim muaj qhov tsis zoo xws li kev xav tau kev txhaj tshuaj thiab kev pheej hmoo ntawm cov leeg leeg tuag tes tuag taw, cov kws tshawb fawb tau pib txhim kho kev nyab xeeb thiab yooj yim dua lwm cov khoom xyaw. Lub caij no, qhov tshwm sim ntawm Acetyl Hexapeptide-3 (Argireline) tau tso lub hauv paus tshawb fawb rau botulinum toxin-zoo li peptides, muab lub tswv yim tseem ceeb rau kev tshawb pom ntawm SNAP 8 Powder.
R & D txheej txheem
Raws li cov neurotransmitter kis tau tus mob, cov kws tshawb fawb tau txheeb xyuas tias SNAP -25 protein yog tus yuam sij rau kev cog lus ntawm cov leeg ntawm lub ntsej muag. Los ntawm kev ua raws li nws cov N-terminal fragment, ob lub amino acid chains tau ntxiv rau Acetyl Hexapeptide-3 txhawm rau txhim kho kev ua haujlwm thiab kev ruaj ntseg ntawm peptide, ua rau muaj kev vam meej synthesis ntawm Acetyl Octapeptide-3, uas yog SNAP 8. Tom qab optimization ntawm purification txheej txheem enabled zus tau tej cov SNAP 8 Powder thiab daim ntawv thov zoo heev. Cov txiaj ntsig R & D ntsig txog tau maj mam luam tawm tom qab xyoo 2010.
Cov ntawv thov pib
Tom qab xyoo 2011, qhov kev tiv thaiv -wrinkle kev ua tau zoo ntawm SNAP 8 Powder tau txheeb xyuas los ntawm kev sim tshuaj. Nws tuaj yeem cuam tshuam kev tsim ntawm SNARE complex thiab maj mam tswj cov leeg nqaij tsis tas yuav tsum tau txhaj tshuaj, sawv cev rau kev txhim kho tseem ceeb hauv kev nyab xeeb. Txij thaum ntawd los, nws tau maj mam tau txais los ua ib qho tseem ceeb los tiv thaiv -wrinkle raw khoom hauv kev tsim cov khoom tu tawv nqaij, tawm los ua ib qho tshiab los tiv thaiv -wrinkle muaj nyob rau hauv siab-kawg skincare sector thiab ua kom tiav qhov kev hloov pauv los ntawm kev tshawb fawb hauv chav kuaj mus rau kev siv tswv yim.
FAQ
Snap 8 peptide siv rau dab tsi?
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Anti Wrinkle, Anti-Kev laus, Kev kho kab mob zoo, Smoothening, Snap 8 Serum Booster yog tsim tshwj xeeb rau kev siv tshuaj pleev ib ce, tsom rautxo cov tsos ntawm cov kab qhia thiab wrinkles rau ib tug ntau hluas thiab du daim tawv nqaij kev ntxhib los mos.
Puas yog snap 8 zoo dua li Argireline?
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Txoj kev tshawb no qhia tau tiasSnap 8 yog kwv yees li 30% nquag tshaj nws niam txiv peptide Argireline. Nov yog vim li cas: Ntau cov amino acids : Snap 8 muaj 8 amino acids thaum Argireline muaj 6. Cov txiaj ntsig zoo dua : Cov kev tshawb fawb qhia Snap 8 txo cov wrinkles zoo dua.
Nws siv sijhawm ntev npaum li cas thiaj pom cov txiaj ntsig ntawm Snap 8?
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peb mus rau rau lub lis piam
Ntev npaum li cas SNAP 8 coj los qhia cov txiaj ntsig. Tsis zoo li Botox uas qhia cov teebmeem hauv hnub, SNAP 8 ua haujlwm tau zoo. Cov neeg siv feem ntau pib pom cov tawv nqaij smoother kev ntxhib los mos thiab txo cov kab qhia hauvpeb mus rau rau lub lis piamntawm kev siv txhua hnub zoo ib yam.
Cim npe nrov: snap 8 hmoov, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom