Guanosine 5'-monophosphate disodium ntsevyog cov khoom noj ntxiv nrog cov mis molecular C10H12N5O8P · Na2 los yog Na2C10H12N5O8P · 2H2O, CAS 5550-12-9. Tsis muaj xim rau dawb crystalline, los yog dawb crystalline hmoov, muaj li 7 molecules ntawm crystalline dej. Nws yog qab, nrog rau qhov pib saj ntawm 0.0125g / 100mL thiab saj siv ntawm 2.3 npaug ntawm sodium inosinate. Nws muaj cov nyhuv synergistic nrog sodium glutamate. Nws tsis yog hygroscopic, soluble hauv dej, thiab cov tshuaj aqueous ruaj khov. Hauv cov kua qaub, nws tuaj yeem decomposed thiab rhuav tshem los ntawm phosphatase. Nws tuaj yeem decomposed ntawm 190 ~ 200 degree, me ntsis soluble hauv ethanol, thiab yuav luag insoluble hauv ether. Nws yog siv los ua cov khoom noj qab haus huv rau cov kaus poom zaub mov, nqaij qaib, ntses, zaub mov ceev, kua zaub, thiab lwm yam.
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Tshuaj Formula |
C10H12N5Na2O8P |
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Exact Mass |
407 |
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Molecular Luj |
407 |
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m/z |
407 (100.0%), 408 (10.8%), 408 (1.8%), 409 (1.6%) |
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Elemental Analysis |
C, 29,50; H, 2,97; N, 17.20; Na, 11.29; O, 31,43; ib 7,61 |
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Nyob ruaj khov nyob rau hauv ib txwm kub thiab siab, tsis muaj xim rau dawb crystalline los yog crystalline hmoov, feem ntau muaj 7 molecules ntawm siv lead ua dej, tsw, nrog ib tug tshwj xeeb tsw zoo ib yam li cov nceb. Lub melting point yog tsis pom tseeb, browning ntawm 240 degree, thiab decomposition ntawm 250 degree. Nws ruaj khov rau acid, alkali, ntsev thiab cua sov. Nws muaj zog noo noo nqus thiab yooj yim soluble hauv dej (25 degree, 25%). Tus nqi pH ntawm 5% aqueous tov yog 7.0 ~ 8.5, thiab nws yog me ntsis soluble hauv ethanol, acetone thiab ether. Lub qhov ncauj LD5010g / kg ntawm nas tsis tas yuav muaj kev cai tshwj xeeb rau ADI (FAO/WHO, 1994).
Guanosine 5'-monophosphate disodium ntsev, abbreviated li GMP Na ₂, yog ib qho tseem ceeb ntawm cov zaub mov flavoring tus neeg sawv cev nrog tshwj xeeb freshness thiab ntau yam kev siv. Hauv kev lag luam khoom noj khoom haus, nws tau siv dav hauv ntau hom khoom noj vim nws qhov tseem ceeb ntawm kev ua kom muaj txiaj ntsig zoo, ruaj khov, thiab kev nyab xeeb.
Daim ntawv thov raws li ib tug tsw enhancer
1. Cov yam ntxwv tshiab ntawm kev txhim kho
Freshness siv: Lub umami siv ntawm 5 '- guanylate disodium yog 2.3 npaug ntawm sodium inosinate (IMP Na ₂), ua rau nws ua tau zoo umami enhancer.
Synergistic nyhuv: Thaum siv ua ke nrog monosodium glutamate (MSG), nws tuaj yeem tsim cov txiaj ntsig tseem ceeb hauv kev txhim kho freshness. Thaum sib xyaw, nws qhov ntau npaum li cas yog li 1% mus rau 5% ntawm tag nrho cov nyiaj ntawm monosodium glutamate, uas tuaj yeem txhim kho cov zaub mov tshiab.
Cov yam ntxwv tsw: Nws muaj qhov tshwj xeeb umami tsw zoo ib yam li cov nceb shiitake, uas tuaj yeem muab cov khoom noj muaj txiaj ntsig thiab nplua nuj umami tsw.
2. Daim ntawv thov piv txwv
Seasoning: Ntxiv 5 '- guanylate disodium rau soy sauce, vinegar, sauce thiab lwm yam seasonings tuaj yeem txhim kho lawv cov freshness thiab ua rau lawv qab dua.
Khoom noj khoom haus yooj yim: Hauv cov noodles instant, instant soup hmoov, ceev ceev noodles thiab lwm yam khoom noj yooj yim, 5 '- guanylate disodium feem ntau yog siv ua ke nrog monosodium glutamate, sodium inosinate, thiab lwm yam los txhim kho qhov freshness thiab tsw ntawm cov zaub mov.
Cov khoom noj nqaij: Hauv cov khoom noj nqaij xws li nqaij npua, hnyuv ntxwm, nplej- nqaij dumplings, ntxiv qhov tsim nyog ntawm 5 '- guanylate disodium, uas tuaj yeem txhim kho cov saj ntawm cov nqaij thiab ua kom nws qab.
Cov khoom hauv dej: Ntxiv 5 '- guanylate disodium rau cov ntses pob, cov pob cw, cov nqaij nruab deg thiab lwm cov khoom hauv dej tuaj yeem txhim kho lawv cov freshness thiab tsw, thiab txhim kho lawv cov khoom zoo.
Cov zaub mov hauv kaus poom: Ntxiv 5 '- guanylate disodium tuaj yeem txhim kho qhov tshiab thiab saj ntawm ntau yam khoom noj kaus poom, xws li cov kaus poom kua zaub thiab cov zaub hauv kaus poom.
3. Cov qauv kev cai
Lub Tebchaws Kev Nyab Xeeb Khoom Noj Khoom Haus rau Kev Siv Cov Khoom Noj Ntxiv hauv Suav Teb (GB 2760-2014) tso cai rau kev siv nruab nrab ntawm 5 '- guanylate disodium hauv ntau yam khoom noj raws li kev xav tau ntau lawm.
Lub Codex Alimentarius Commission (CAC), European Commission, thiab lwm tus kuj tau pom zoo nws siv los ua ib qho tsw qab hauv cov zaub mov.
Daim ntawv thov raws li kev noj haus fortifier
1. Noj zaub mov muaj nuj nqi
Muab cov khoom noj khoom haus nucleotide: 5 '- guanylate disodium yog cov khoom siv nucleotide uas koom nrog cov metabolism hauv lub zog thiab cov protein synthesis hauv lub cev, thiab muaj txiaj ntsig zoo rau tib neeg kev noj qab haus huv.
Txhawb cov metabolism: Nucleotides yog cov khoom tseem ceeb hauv cov kab mob metabolic, koom nrog ntau yam tshuaj lom neeg biochemical thiab txhawb cov cell metabolism thiab kev loj hlob.
2. Daim ntawv thov piv txwv
Cov khoom noj me nyuam mos: Ntxiv cov nyiaj kom tsim nyog ntawm 5 '- guanylate disodium hauv cov me nyuam mos mis hmoov, Rice noodles thiab lwm yam khoom noj los muab cov khoom noj uas tsim nyog rau nucleotide thiab txhawb lawv txoj kev loj hlob thiab kev loj hlob.
Khoom noj khoom haus noj qab haus huv: Ntxiv 5 '- guanylate disodium rau qee cov khoom noj noj qab haus huv, xws li cov uas txhim khu kev tiv thaiv kab mob thiab tiv thaiv kev qaug zog, tuaj yeem txhim kho lawv cov khoom noj muaj txiaj ntsig thiab cov txiaj ntsig kev noj qab haus huv.
3. Cov qauv kev cai
Raws li kev noj zaub mov zoo, kev siv 5 '- guanylate disodium yuav tsum ua raws li cov cai thiab cov qauv hauv Suav teb thiab thoob ntiaj teb kom muaj kev nyab xeeb thiab muaj txiaj ntsig zoo ntawm cov zaub mov.
Daim ntawv thov raws li ib tug preservative
1. Preservation mechanismInhibition ntawm microbial kev loj hlob: 5 '- guanylate disodium muaj qee yam tshuaj tua kab mob, uas tuaj yeem cuam tshuam kev loj hlob thiab kev loj hlob ntawm cov kab mob hauv cov zaub mov thiab txuas ntxiv lub neej txee ntawm cov zaub mov.
Khaws cov zaub mov tshiab: Los ntawm inhibiting kev loj hlob ntawm cov kab mob, tswj cov khoom noj tshiab thiab zoo.
3. Cov qauv kev cai
Raws li kev khaws cia, kev siv 5 '- guanylate disodium yuav tsum ua raws li cov cai thiab cov qauv hauv Suav teb thiab thoob ntiaj teb kom muaj kev nyab xeeb thiab zoo ntawm cov zaub mov.
2. Daim ntawv thov piv txwv Cov khoom siv nqaij: Ntxiv 5 '- guanylate disodium rau cov khoom noj nqaij xws li nqaij npua thiab hnyuv ntxwm tuaj yeem cuam tshuam cov kab mob loj hlob thiab ua rau lub neej ntev.
Cov khoom hauv dej: Ntxiv 5 '- guanylate disodium rau cov ntses pob, cov pob cw thiab lwm cov khoom hauv dej tuaj yeem tswj tau qhov tshiab thiab zoo ntawm cov khoom.
Cov khoom siv mis nyuj: Ntxiv qhov tsim nyog ntawm 5 '- guanylate disodium rau cov khoom siv mis nyuj xws li yogurt thiab cheese tuaj yeem cuam tshuam microbial kev loj hlob thiab ua rau lub neej ntev.
Lwm daim ntawv thov
1. Daim ntawv thov hauv cov khoom siv tshuaj txhua hnub
Muab qhov tshiab thiab tsw: ntxiv qhov tsim nyog ntawm 5 '- guanylate disodium nyob rau hauv ntau yam khoom siv tshuaj niaj hnub xws li tshuaj ntxuav lub ntsej muag, tshuaj pleev kom zoo nkauj, ua- dej, tshuaj zawv plaub hau, tshuaj txhuam hniav, da dej gel thiab daim npog ntsej muag kom muab lub ntsej muag qab thiab tsw, thiab txhim kho kev siv thiab kev nplij siab ntawm cov khoom.
2. Kev siv hauv cov khoom lag luam luam yeeb
Fragrance thiab antifreeze moisturizing: Hauv cov khoom lag luam luam yeeb, 5 '- guanylate disodium tuaj yeem hloov glycerol los ua ib qho flavoring thiab antifreeze moisturizing tus neeg sawv cev rau kev haus luam yeeb, txhim kho aroma thiab saj ntawm cov khoom luam yeeb.
3. Daim ntawv thov hauv pub
Txhim kho qhov saj thiab tsw ntawm pub: Ntxiv qhov tsim nyog ntawm 5 '- guanylate disodium rau pub tuaj yeem txhim kho nws saj thiab tsw, thiab ua rau kom qab los noj mov thiab plab zom mov ntawm cov tsiaj.
Txhawb nqa tsiaj loj hlob thiab txhawb kev tiv thaiv kab mob: Nucleotide tshuaj muaj qee yam kev txhawb nqa tsiaj loj hlob thiab kev tiv thaiv kab mob, thiab ntxiv 5 '- guanylate disodium tuaj yeem txhim kho cov khoom noj muaj txiaj ntsig zoo.
Cov kev cai thiab cov qauv
1. Cov kev cai hauv tsev
Lub Tebchaws Kev Nyab Xeeb Khoom Noj Khoom Haus rau Kev Siv Cov Khoom Noj Ntxiv hauv Suav Teb (GB 2760-2014) muab cov kev cai meej meej ntawm cov kev cai, ntau npaum li cas, thiab cov ntawv cim rau kev siv disodium 5 '- guanylate.
Cov qauv no tso cai rau kev siv nruab nrab ntawm 5 '- guanylate disodium nyob rau hauv ntau yam khoom noj raws li kev xav tau ntau lawm, thiab qhia nws qhov kev siv ntau tshaj plaws hauv cov khoom noj sib txawv.
2. Cov kev cai thoob ntiaj teb
Lub General Codex Standard for Food Additives tsim los ntawm Codex Alimentarius Commission (CAC) tso cai rau siv disodium 5 '- guanylate ua ib tug flavoring agent, khoom noj khoom haus enhancer, preservative, thiab lwm yam nyob rau hauv ntau yam khoom noj.
Cov European Union, Tebchaws Meskas thiab lwm lub tebchaws thiab cheeb tsam kuj tau tsim cov kev cai cuam tshuam txog kev siv 5 '- guanylate disodium hauv cov zaub mov kom ntseeg tau tias nws muaj kev nyab xeeb thiab ua haujlwm tau zoo.
5 '- guanylate disodium, ua ntau yam khoom noj khoom haus additive, muaj kev thov dav dav hauv kev lag luam khoom noj. Nws qhov tseem ceeb tshiab ua kom muaj txiaj ntsig zoo, kev ruaj ntseg zoo, thiab kev nyab xeeb ua rau nws muaj txiaj ntsig zoo rau kev siv hauv cov khoom noj sib txawv. Nrog rau txoj kev loj hlob ntawm kev lag luam khoom noj khoom haus thiab kev xav tau ntau ntxiv rau cov zaub mov noj qab haus huv los ntawm cov neeg siv khoom, daim ntawv thov kev cia siab ntawm 5 '- guanylate disodium yuav ntau dua. Hauv kev tshawb fawb yav tom ntej, daim ntawv thov ntawm 5 '- guanylate disodium hauv cov khoom noj tshiab thiab nws cov teebmeem kev sib koom ua ke nrog lwm cov khoom noj khoom haus tuaj yeem tshawb nrhiav ntxiv, muab ntau txoj hauv kev rau kev tsim khoom noj khoom haus.
Cov ntaub ntawv yooj yim
Suav Lub Npe: 5'-Guanosine Diphosphate Disodium ntsev
Lub npe Askiv:Guanosine 5'-monophosphate Disodium ntsev
CAS Nr .: 5550-12-9
Molecular Formula: C₁₀H₁₂N₅Na₂O₈P·xH₂O (x sawv cev rau cov dej crystalline molecules, feem ntau 7)
Molecular Luj: 407.18 (tsis suav cov dej crystalline)
Cov tsos mob thiab cov khoom: Dawb crystalline hmoov, tsw tsw, nrog ib tug txawv aroma zoo li shiitake nceb.
Solubility: Yooj yim soluble hauv dej (solubility> 50g / L ntawm 25 degree), me ntsis soluble hauv ethanol, acetone, thiab ether.
Stability: ruaj khov ntawm qhov kub thiab txias, tiv taus acids, hauv paus, ntsev, thiab cua sov. Txawm li cas los xij, nws yuav decompose ntawm qhov kub thiab txias (piv txwv li, 250 degree).
Txoj kev tsim khoom
Txoj kev tsim khoom ntawm 5'-guanosine diphosphate disodium feem ntau suav nrog enzymatic hydrolysis thiab fermentation txoj kev. Ntawm lawv, txoj kev fermentation yog siv tau rau hauv kev lag luam, tshwj xeeb tshaj yog ob txoj kev -kauj ruam thiab kev sib xyaw ua ke ntawm kev siv tshuaj lom neeg thiab tshuaj synthesis. Hauv qab no yog cov lus qhia ntxaws:
Enzymatic hydrolysis
5'-Guanosine di-nucleotide yog npaj los ntawm hydrolysis ntawm ribonucleic acid (RNA). Txawm li cas los xij, txoj kev no yog kim thiab cov txiaj ntsig tsis ruaj khov, yog li nws tsis tshua siv hauv kev lag luam.
Txoj kev fermentation
Ob -kab ruam txoj kev:
Siv cov piam thaj los ua cov pa roj carbon monoxide thiab cov kab mob sib kis ntawm Bacillus subtilis rau fermentation, guanosine yog thawj zaug, nrog rau qib ntau txog 10.5g / L. Tom qab ntawd, guanosine yog acidified hauv cov tshuaj pyridine siv trichlorophosphoric acid kom tau guanosine acid. Txoj kev no muaj cov kauj ruam meej thiab cov txiaj ntsig siab, thiab yog ib qho ntawm cov kev npaj siv ntau hauv kev lag luam.
Kev sib xyaw ntawm biosynthesis thiab chemical synthesis method:
Hauv qab pH ntawm 7, siv cov bacillus loj (Tsis yog. 336) rau ferment qabzib (8%) rau 90 teev, 5-amino-4-formamidinonucleoside (AICAr) yog tsim los ntawm qib 15g/L. Tom qab ntawd, AICAr yog muab rho tawm los ntawm kev sib pauv ion, concentrated, qhuav, yaj hauv methanol uas muaj NaOH, thiab rhuab ua ke nrog carbon disulfide los hloov nws mus rau 2-sulfamininosine. Thaum kawg, nws yog oxidized nrog hydrogen peroxide, tshaj ammonia dej ntxiv, thiab rhuab kom tau guanosine, uas yog ces phosphorylated kom tau guanosine acid. Txoj kev no muab cov txiaj ntsig zoo ntawm biosynthesis thiab tshuaj synthesis thiab tuaj yeem npaj tau zoo 5'-guanosine di-nucleotide.
Cov txheej txheem ntau lawm ntws
Ua ob-txoj kev hauv cov txheej txheem fermentation ua piv txwv, cov txheej txheem tsim tawm ntawm 5'-guanosine di-nucleotide feem ntau suav nrog cov kauj ruam hauv qab no:
Xaiv ib hom kab mob uas tsim nyog ntawm Bacillus subtilis raws li hom kev tsim khoom, thiab ua kev cog qoob loo thiab nthuav tawm kev loj hlob.
Hloov cov kab mob cultivated mus rau hauv lub tank fermentation, siv cov piam thaj los ua cov pa roj carbon monoxide, thiab nqa tawm fermentation cultivation. Thaum lub sij hawm fermentation txheej txheem, tsis xws li kub, pH tus nqi, thiab yaj cov ntsiab lus oxygen yuav tsum tau tswj xyuas kom muaj kev loj hlob zoo thiab metabolism ntawm cov kab mob.
Tom qab fermentation tiav lawm, cais cov kab mob ntawm cov fermentation broth los ntawm centrifugation thiab pom, thiab ces extract guanosine los ntawm fermentation broth siv ion pauv thiab adsorption txoj kev.
Acidify cov extracted guanosine hauv cov tshuaj pyridine nrog trichlorophosphoric acid kom tau guanosinate.
Ua kom zoo dua cov guanosinate thiab tshem tawm cov impurities thiab cov khoom siv tsis zoo, tom qab ntawd tau txais 5'-guanosine di-nicotinate khoom los ntawm cov tshuaj tsuag kom qhuav thiab lwm txoj kev.
Kev Tswj Xyuas Zoo
Thaum lub sijhawm tsim khoom, kev tswj hwm nruj ntawm cov khoom siv raw, cov khoom nruab nrab, thiab cov khoom tiav yuav tsum tau ua kom ntseeg tau tias cov khoom siv purity thiab zoo raws li cov qauv tsim. Tshwj xeeb, nws suav nrog:
Cov khoom siv raw tswj
Ua kev soj ntsuam zoo ntawm cov khoom siv raw xws li qabzib kom ntseeg tau tias lawv ua tau raws li qhov yuav tsum tau ua.
Kev tswj nruab nrab
Tsis tu ncua kuaj cov ntsiab lus guanosine hauv cov kua fermentation kom ntseeg tau tias kev ruaj ntseg ntawm cov txheej txheem fermentation.
Kev tshuaj xyuas cov khoom tiav
Ntsuam xyuas qhov purity, noo noo, hnyav hlau, thiab lwm yam ntawm cov khoom tiav kom ntseeg tau tias lawv ua raws li cov qauv tsim nyog.
Daim ntawv thov teb
5'-guanylate disodium yog ib qho khoom noj khoom haus tseem ceeb thiab cov tshuaj nruab nrab nrog ntau hom kev thov. Hauv kev lag luam khoom noj khoom haus, nws tsuas yog siv los ua cov tshuaj tsw qab (umami enhancer), thiab yog tov nrog sodium glutamate (monosodium glutamate) thiab 5'-inosinate disodium los tsim cov nyhuv umami ntau, txhim kho saj thiab zoo ntawm cov zaub mov. Tsis tas li ntawd, nws tseem tuaj yeem siv rau hauv thaj chaw tshuaj thiab tshuaj pleev ib ce.
Cov lus nug nquag
Dab tsi yog disodium guanosine 5 monophosphate?
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Disodium Guanosine 5 Monophosphate + lactoferrin yogsiv los kho cov tsis muaj hlau tsis muaj hlau thiab hlau tsis muaj peev xwm anemia hauv cov poj niam cev xeeb tub. Nws txo qis qib ntawm hepcidin (ib qho hlau- tswj cov tshuaj hormones). Nws tsub kom hlau nqus thiab yog li refills hlau khw.
Guanosine monophosphate ua dab tsi?
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Guanosine Monophosphate (GMP) yog molecule uasua tus thawj coj rau kev tsim cov cyclic GMP (cGMP), tus xa xov thib ob tseem ceeb hauv kev taw qhia.
Puas yog disodium guanylate zoo lossis phem rau koj?
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Disodium guanylate yogsuav tias muaj kev nyab xeeb rau cov neeg feem coobthiab tau txais kev pom zoo los ntawm cov neeg saib xyuas kev nyab xeeb khoom noj loj thoob ntiaj teb, suav nrog FDA. Txawm li cas los xij, cov neeg uas muaj kab mob gout lossis qib siab uric acid yuav tsum txwv tsis pub lawv noj, vim tias cov tshuaj ntxiv no muaj cov purines uas tuaj yeem ua rau uric acid ntau ntxiv.
Puas yog disodium guanylate tsis zoo rau lub raum?
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Cov neeg uas muaj gout lossis keeb kwm ntawm uric acid raum pob zeb yuav tsum tsis txhob muaj disodium guanylate. Qhov no yog vim tias guanylates feem ntau metabolize rau purines, uas yog cov tebchaw uas tuaj yeem nce qib uric acid hauv koj lub cev.
Dab tsi yog cov khoom noj muaj siab hauv guanylate?
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Ob hom nucleotides uas ua rau feem ntau rau umami saj, inosinate thiab guanylate, kuj muaj nyob rau hauv ntau yam khoom noj. Inosinate feem ntau pom muaj nyob rau hauv cov nqaij thiab ntses thaum guanylate muaj ntau dua hauv cov nceb tsev neeg xws liqhuav shiitake nceb.
Cim npe nrov: guanosine 5'-monophosphate disodium ntsev cas 5550-12-9, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom