Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm 1-cbz-4-methylene-piperidine cas 138163-12-9 hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo 1-cbz-4-methylene-piperidine cas 138163-12-9 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Tshaj tawm
Peb tsis muab txhua yam tshuaj ntawm piperidine series, txawm tias muaj peev xwm tau txais piperidine los yog piperidone chemicals!
Txawm yuav txwv los tsis tau! Peb tsis muab!
Yog hais tias nws yog nyob rau hauv peb lub webiste, nws tsuas yog mus xyuas cov ntaub ntawv ntawm cov tshuaj compound.
Peb Hlis . 25th 2025
1-Cbz-4-methylene-piperidine, tseem hu ua 1-benzyloxycarbonyl-4-methylpiperidine, Benzyl 4-methylene-1-piperidinecarboxylate, N-Cbz-4-methylenepiperidine, yog ib yam tshuaj uas muaj cov tshuaj formula, molecular hnyav, thiab lub cev muaj zog. Cov tsos mob yog dawb crystalline hmoov, khaws cia nyob rau hauv chav tsev kub nyob rau hauv ib tug kaw, qhuav ib puag ncig. Feem ntau yog siv rau kev tshawb fawb thwmsim, nws yog tsuas yog siv raws li ib tug kws tshuaj intermediate nyob rau hauv kws tshuaj thiab muaj ib tug tseem ceeb tshuaj thiab pharmacological nqi. Nws tseem ua lub luag haujlwm hauv kev tsim cov organic synthesis thiab tshuaj lom neeg.
Cov ntaub ntawv ntxiv ntawm chemical compound:
|
Tshuaj Formula |
C14H17NO2 |
|
Exact Mass |
231.13 |
|
Molecular Luj |
231.30 |
|
m/z |
231.13 (100.0%),232.13 (15.1%),233.13 (1.1%) |
|
Elemental Analysis |
C,72.70; H,7.41; N,6.06; O,13.83 |
|
Boiling point |
146℃(Nias: 1 Torr) |
|
Qhov ntom |
1.11 ± 0.1 g / cm3 (Tshaj tawm) |
|
|
|
Cov khoom siv raw
1-Cbz-4-methylene-piperidinetuaj yeem siv los ua cov khoom siv raw rau kev tsim khoom thiab muaj peev xwm siv dav hauv kev lag luam xws li tshuaj lom neeg thiab tshuaj.
Nws tuaj yeem ua haujlwm tseem ceeb hauv nruab nrab rau kev sib txuas ntawm lwm cov ntaub ntawv tshuaj. Nyob rau hauv cov txheej txheem ntawm cov tshuaj synthesis, nws tuaj yeem hloov mus rau hauv cov tebchaw nrog cov haujlwm tshwj xeeb thiab cov khoom siv los ntawm cov tshuaj lom neeg, uas muaj cov txiaj ntsig tseem ceeb hauv kev tsim khoom.
tshuaj intermediates
Hauv thaj chaw ntawm cov tshuaj zoo, nws tseem tuaj yeem siv los ua cov khoom siv raw rau kev tsim cov tshuaj zoo. Cov tshuaj zoo no yuav muaj lub cev tshwj xeeb, tshuaj lom neeg lossis kev ua haujlwm lom neeg, thiab muaj kev siv dav hauv kev tsim khoom.Nws yog ib qho tseem ceeb hauv nruab nrab ntawm cov tshuaj synthesis. Pharmaceutical intermediates yog cov ntaub ntawv tseem ceeb hauv cov txheej txheem synthesis ntawm cov ntaub ntawv raw khoom.
Ua lub luag haujlwm tseem ceeb hauv kev sib xyaw thiab kev npaj tshuaj. Nws yog siv los ua ke ntau yam tshuaj molecules complex thiab yog ib qho tseem ceeb ntawm kev tshawb fawb thiab kev loj hlob ntawm kws tshuaj chemistry.
Los ntawm kev siv tshuaj lom neeg ntxiv, cov khoom sib xyaw tuaj yeem hloov mus rau hauv ib qho kev sib xyaw nrog cov tshuaj pharmacological, uas tuaj yeem siv rau hauv kev tsim thiab tsim cov tshuaj. Nws yog siv los ua ke ntau yam tshuaj molecules complex thiab yog ib feem tseem ceeb ntawm kev tshawb fawb thiab kev loj hlob ntawm kws tshuaj chemistry.
Lwm daim ntawv thov
Nws kuj tseem muaj peev xwm siv tau rau lwm qhov chaw, xws li kev tshawb fawb tshuaj, cov ntaub ntawv tshawb fawb, thiab lwm yam. Txawm li cas los xij, cov ntawv thov no yuav tsum tau txiav txim siab raws li cov kev sim thiab kev tshawb fawb tshwj xeeb. Cov kws tshawb fawb tuaj yeem siv nws los ua ntau yam kev sim tshuaj lom neeg thiab kev sim tshuaj lom neeg los tshawb nrhiav cov tshuaj lom neeg tshiab thiab cov txheej txheem lom neeg. Qhov no yog qhov tseem ceeb heev rau kev txhawb nqa kev loj hlob ntawm thaj chaw ntawm chemistry thiab biology.
Cov kev phiv thiab kev phom sij ntawm cov tshuaj no yog dab tsi?
Daim tawv nqaij thiab qhov muag khaus
Vim muaj peev xwm irritants ntawm1-Cbz-4-methylene-piperidine, nws yuav ua rau tsis xis nyob los yog kev puas tsuaj thaum sib cuag nrog daim tawv nqaij lossis ob lub qhov muag. Nws raug nquahu kom hnav cov khoom tiv thaiv tsim nyog xws li hnab looj tes thiab tsom iav thaum siv.
Ua pa system cuam tshuam
Kev nqus tau los ntev ntev lossis raug rau qhov siab yuav ua rau ua pa tsis xis nyob, xws li hnoos, ua pa nyuaj, thiab lwm yam.Qhov cua zoo yuav tsum tau ua kom ntseeg tau thaum siv, thiab kev nqus pa ntev yuav tsum zam.
Gastrointestinal tsis xis nyob
Kev noj qab haus huv txaus ntshai
Lub sij hawm ntev raug los yog raug rau siab ntau ntawm Benzyl 4-methylene-1-piperidinecarboxylate tej zaum yuav muaj kev cuam tshuam rau kev noj qab haus huv mus sij hawm ntev. Nws raug nquahu kom kuaj xyuas kev noj qab haus huv tsis tu ncua thiab ua raws li cov txheej txheem kev nyab xeeb.
Flammable thiab tawg
Cov khoom sib xyaw no tuaj yeem ua rau tawg thiab tawg, yog li cov cai tswj kev nyab xeeb yuav tsum tau ua raws li nruj me ntsis thaum khaws cia thiab siv. Khaws kom deb ntawm qhov hluav taws kub thiab cua sov, thiab khaws cia rau hauv qhov chaw txias thiab qhov cua.
Ib puag ncig muaj kuab paug
Kev tuav tsis raug lossis tso tawm cov khoom pov tseg uas muaj qhov sib xyaw no tuaj yeem ua rau muaj kuab paug rau ib puag ncig.Peb yuav tsum ua raws li kev cai ib puag ncig thiab tswj cov khoom pov tseg kom zoo
Cov kev ceev faj
- Thaum siv Benzyl 4-methylene-1-piperidinecarboxylate, ua tib zoo nyeem cov khoom phau ntawv kom nkag siab txog nws cov txheej txheem kev nyab xeeb thiab kev ceev faj.
- Yog tias muaj qhov tsis xis nyob lossis xav tias muaj cov tsos mob lom, nrhiav kev kho mob tam sim ntawd thiab qhia rau tus kws kho mob txog keeb kwm kev sib cuag.
- Thaum khaws cia, xyuas kom meej tias lub thawv kaw thiab muab tso rau hauv qhov chaw txias thiab qhov cua, kom deb ntawm qhov hluav taws kub thiab cua sov.
- Thaum pov tseg cov pov tseg, cov kev cai hauv cheeb tsam ib puag ncig yuav tsum tau ua raws thiab cov pov tseg yuav tsum tau ua kom zoo.
Cov tshuaj lom ntawm cov tshuaj no
Lub sij hawm ntev toxicity
Lub sij hawm ntev raug rau 1-CBZ-4-methylpiperidine tuaj yeem ua rau muaj kev phom sij ntau rau lub cev. Cov dej num no yuav muaj xws li: Daim siab thiab lub raum puas : Kev noj qab haus huv ntev lossis raug rau cov khoom no tuaj yeem ua rau lub siab thiab ob lub raum puas, cuam tshuam rau lawv txoj haujlwm ib txwm muaj.Neurological puas: Cov khoom no yuav muaj kev cuam tshuam rau lub paj hlwb, ua rau cov tsos mob xws li kiv taub hau, mob taub hau, tsaug zog, thiab kev xav qeeb. Kev tsim menyuam yaus thiab kev loj hlob toxicity: Qee qhov xwm txheej, cov tshuaj no tuaj yeem ua rau muaj kev phom sij. fetus.Carcinogenicity: Txawm hais tias tam sim no tsis muaj pov thawj tseeb los qhia tias 1-CBZ-4-methylpiperidine yog carcinogenic, ntev mus rau qee yam tshuaj yuav ua rau muaj kev pheej hmoo ntawm mob qog noj ntshav.
Mob toxicity
Tam sim no, cov ntaub ntawv mob toxicity ntawm qhov no yuav tsis ua kom tiav lossis nthuav dav. Txawm li cas los xij, feem ntau hais lus, cov tshuaj yuav ua rau muaj kev phom sij rau lub cev thaum raug mob, xws li khaus qhov muag, tawv nqaij, lossis ua pa ua pa, ua rau muaj kev tsis haum tshuaj, lossis ua rau muaj kev puas tsuaj rau lub hauv paus paj hlwb, kab mob plawv, lossis kab mob xws li daim siab thiab ob lub raum. Cov kev kawm tshwj xeeb thiab kev tshwm sim ntawm cov tshuaj lom no yuav txawv ntawm cov tib neeg.
Lwm yam kev pheej hmoo
Ntxiv nrog rau cov tshuaj lom neeg uas tau hais los saum no, 1-CBZ-4-methylpiperidine kuj tseem tuaj yeem ua rau muaj kev phom sij rau ib puag ncig thiab ecosystems. Piv txwv li, nws tuaj yeem sib sau ua ke hauv dej hauv lub cev thiab ua rau muaj kev phom sij rau cov kab mob hauv dej, lossis kis tau los ntawm cov khoom noj khoom haus thiab cuam tshuam rau tib neeg kev noj qab haus huv.
Dab tsi yog lwm txoj hauv kev rau qhov sib xyaw no
Cov qauv analogues
Tshawb nrhiav cov tebchaw uas muaj cov qauv zoo sib xws tab sis cov khoom sib txawv rau 1-CBZ-4-methylpiperidine hloov pauv. Cov tebchaw no yuav muaj qhov zoo sib xws los yog lub cev muaj zog, tab sis yuav txawv ntawm cov tshuaj toxicity, stability, lossis nqi.
Synthesis txoj kev optimization
Los ntawm kev ua kom zoo ntawm txoj kev sib txuas thiab siv lwm yam khoom siv tau yooj yim lossis muaj kev nyab xeeb dua rau kev sib txuas nrog cov haujlwm zoo ib yam lossis zoo sib xws, nws hloov tsis ncaj 1-CBZ-4-methylenopiperidine.
Kev tshawb nrhiav kev lag luam thiab kev sab laj
Los ntawm kev tshawb fawb txog kev lag luam thiab kev sab laj nrog cov kws tshaj lij lossis cov koom haum hauv cov haujlwm uas cuam tshuam, nkag siab seb puas muaj kev npaj ua ntej -ua lwm txoj hauv kev lag luam tam sim no. Cov kev xaiv no yuav tau dhau los ntawm kev sim ntau thiab siv tau, nrog rau kev ua tau zoo dua lossis qis dua.
Muaj nuj nqi analogues
Raws li qhov yuav tsum tau ua ntawm 1-CBZ-4-methylpiperidine hauv cov ntawv thov tshwj xeeb, tshawb nrhiav cov tebchaw uas muaj cov haujlwm zoo sib xws li kev hloov pauv.
Piv txwv li, yog tias 1-CBZ-4-methylpiperidine siv los ua pab pawg tiv thaiv hauv kev siv tshuaj, lwm cov tshuaj nrog cov pab pawg tiv thaiv tuaj yeem nrhiav lwm txoj hauv kev.
Biobased lossis cov khoom siv txuas ntxiv dua tshiab
Nrog rau kev paub txog kev tiv thaiv ib puag ncig thiab kev ua kom nrov ntawm cov tswv yim kev txhim kho kom ruaj khov, ntau thiab ntau tus kws tshawb fawb tau saib xyuas biobased lossis cov khoom siv txuas ntxiv dua tshiab los ua lwm yam tshuaj. Yog tias ua tau, cov ntaub ntawv nyoos no tuaj yeem siv los ua cov sib xyaw ua ke nrog cov haujlwm zoo ib yam lossis zoo ib yam li lwm txoj hauv kev rau 1-CBZ-4-methylenopiperidine.
Kev mob tshwm sim ntawm kev hloov pauv rau qhov sib xyaw no
Hloov nrog cov qauv tshuaj zoo sib xws-Yog tias cov qauv tshuaj hloov pauv zoo ib yam li cov khoom sib xyaw, lawv yuav muaj cov tshuaj pharmacological zoo sib xws thiab cov kev mob tshwm sim. Cov kev mob tshwm sim no tuaj yeem suav nrog:
- Neurological teebmeem: xws li kiv taub hau, mob taub hau, tsaug zog, ncua kev xav, thiab lwm yam.
- Cov teebmeem ntawm digestive: xws li xeev siab, ntuav, mob plab, raws plab, thiab lwm yam.
- Cov teebmeem hauv plawv: xws li palpitations, hauv siab nruj, ntshav siab hloov pauv, thiab lwm yam.
- Kev tsis haum tshuaj: xws li pob khaus, khaus, ua pa nyuaj, thiab lwm yam.
Tsis yog tshuaj lom neeg cov qauv hloov pauv zoo sib xws-Yog tias cov qauv tshuaj ntawm cov khoom hloov pauv txawv txawv ntawm Benzyl 4-methylene-1-piperidinecarboxylate, tab sis lawv muaj cov tshuaj pharmacological zoo sib xws lossis kev ua haujlwm, lawv cov kev mob tshwm sim yuav txawv.
- Cov kev mob tshwm sim tshwj xeeb: Cov kev mob tshwm sim los ntawm cov tshuaj lom neeg tshwj xeeb lossis cov txheej txheem ntawm kev txiav txim ntawm qhov hloov nws tus kheej, xws li qee yam kev hloov pauv uas yuav ua rau lub siab tsis ua haujlwm, lub raum puas, thiab lwm yam.
- Cov kev mob tshwm sim ntev ntev: Qee qhov kev hloov pauv yuav ua rau muaj kev vam khom, tshuaj tiv thaiv, lossis lwm yam kev mob tshwm sim ntev - thaum siv rau lub sijhawm ntev. Kev sib cuam tshuam ntawm cov tshuaj: Cov tshuaj hloov pauv tuaj yeem cuam tshuam nrog lwm cov tshuaj, ua rau muaj txiaj ntsig zoo dua lossis txo qis, thiab txawm tias cov kev mob tshwm sim tshiab.
Cov khoom siv hluav taws xob los yog cov khoom fermentation ua cov khoom hloov pauv -Yog tias lwm txoj hauv kev rau Benzyl 4-methylene-1-piperidinecarboxylate yog cov khoom siv biosynthetic lossis fermented, ces cov kev xaiv no yuav muaj cov tshuaj toxicity qis dua thiab zoo dua biocompatibility. Txawm li cas los xij, lawv tseem yuav muaj qee qhov kev mob tshwm sim, xws li:
- Kev tiv thaiv kab mob: Qee yam khoom siv biosynthetic lossis fermented tuaj yeem ua rau muaj kev tiv thaiv kab mob, xws li ua npaws, ua pob, thiab lwm yam.
- Kev tsis xis nyob hauv plab: Qee yam khoom siv roj ntsha tuaj yeem ua rau lub plab tsis zoo xws li xeev siab, ntuav, thiab lwm yam thaum noj qhov ncauj.
Kev ceev faj-Txoj kev sib txawv ntawm tus kheej: Cov tib neeg sib txawv tuaj yeem muaj qhov sib txawv ntawm cov tshuaj, yog li thaum siv lwm txoj hauv kev rau Benzyl 4-methylene-1-piperidinecarboxylate, yuav tsum tau ua tib zoo saib xyuas tus kheej qhov sib txawv thiab cov lus teb ntawm cov neeg mob.
Kev tshuaj xyuas tshuaj:
- Thaum siv lwm txoj hauv kev, yuav tsum tau soj ntsuam cov tshuaj tsis tu ncua los ntsuas qhov ua tau zoo thiab kev nyab xeeb ntawm cov tshuaj.
- Kev sab laj kev tshaj lij: Ua ntej siv lwm txoj hauv kev rau Benzyl 4-methylene-1-piperidinecarboxylate, nws raug nquahu kom sab laj nrog kws kho mob lossis kws muag tshuaj rau cov lus qhia raug thiab txhim khu kev qha.
FAQ
Nws yog ib qho tseem ceeb nitrogen-muaj heterocyclic organic intermediate, teej tug mus rau qhov hloov pauv piperidine derivative. Nws cov qauv molecular muaj lub nplhaib piperidine, Cbz (benzyloxycarbonyl) tiv thaiv pab pawg ntawm nitrogen atom, thiab methylene ob daim ntawv cog lus ntawm 4-txoj hauj lwm ntawm lub nplhaib piperidine. Lub compound muaj cov pob txha pob txha ruaj khov thiab cov kev ua haujlwm nruab nrab, thiab yog ib qho kev siv ntau lub tsev thaiv hauv cov organic synthesis thiab kev tshawb fawb tshuaj.
Cov molecule muaj qhov hloov pauv tau yooj yim 4-methylene ob daim ntawv cog lus thiab N-terminal Cbz tiv thaiv pab pawg uas tuaj yeem xaiv tau tshem tawm raws li kev tiv thaiv tshwj xeeb. Qhov ob daim ntawv cog lus ntawm 4-site tuaj yeem dhau mus ntxiv, cyclization thiab coupling kev cuam tshuam, ua rau muaj kev hloov pauv ntau yam thiab molecular derivation. Lub caij no, pawg Cbz tuaj yeem tiv thaiv cov qauv amine ntawm piperidine, tsis txhob muaj kev cuam tshuam sab hauv cov txheej txheem synthesis thiab txhim kho cov kev xaiv thiab kev ua haujlwm ntawm cov tshuaj tiv thaiv.
Muab kaw, qhuav thiab qis- qhov kub thiab txias cia, deb ntawm lub teeb thiab noo noo, kom tsis txhob deterioration thiab impurity nce.Mainly siv los ua lub tsev tseem ceeb thaiv rau cov synthesis ntawm piperidine-raws li tshuaj, bioactive molecules thiab zoo tshuaj intermediates.
Cim npe nrov: 1-cbz-4-methylene-piperidine cas 138163-12-9, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom