Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom lag luam zoo tshaj plaws thiab cov chaw muag khoom ntawm cov fluoride tetrahydate CAS 17787-40-5 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale loj zoo tsis zoo tetramethylammonium fluoride CASE 17787-40-5 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Tsis zoo li tsis muaj solubility thiab qhov tsis txaus ntseeg ntawm cov ntsev fluoride hauv cov kuab tshuaj organic,Lub Tetramethylammonium Fluoride Tetrahydatetsim ib qho tshwj xeeb "Nano {{{{{- Nyob Hauv" ionic ib puag ncig "ionic ib puag ncig hauv tsis {1 polar polar kuab tshuaj. Qhov loj tetramethylammonium cation yog zoo li microscopic ", nrog nws cov dej sib xyaw ua ke thiab sib cais" liab qab "acion. Cov cuab yeej no ua rau nws mus dhau lub luag haujlwm ntawm lub fluorinating fluorinating reagent thiab ua ib tug zoo heev "tus qauv tswjfwm thiab cov qauv tswj. Nyob rau hauv synthesis ntawm siab dua hlau {5 5}} ions cov qauv ions los ntawm kev sib txuam me me, yog li kev xaiv ua kom muaj zog ntawm cov khoom siv sib txawv thiab kev ua haujlwm ntawm cov khoom siv. Qhov no "kev tsim kho {{{{{{kev hloov kho" kev ua haujlwm ua rau pom tias nws muaj peev xwm tshwj xeeb hauv cov khoom siv tsim kho kom zoo.
|
|
|
|
Tshuaj Cov Qauv |
C4h20fno4 |
|
Muaj pes tsawg leej |
165.14 |
|
Molecular hnyav |
165.21 |
|
m/z |
165.14 (100.0%), 166.14 (4.3%) |
|
Kev Ntsuam Xyuas |
C, 29.08; H, 12.20; F, 11.50; N, 8.48; O, 38.74 |
Tshuaj lom neeg cov tshuaj fluorinating
TMAF feem ntau yog siv cov tshuaj fluorinating hauv cov synthes synthesis. Nws ua haujlwm ntawm cov ions fluoride, uas tuaj yeem siv los qhia cov tshuaj fluorine atoms rau cov organic molecules. Cov tshuaj fluorine sib txuam feem ntau ua rau lub cev nqaij daim tawv thiab tshuaj lom neeg ntawm cov tebchaw, xws li nce lawv ruaj khov, liplophianity, thiab metabolic kuj.
Fluoride ion qhov chaw: Tmaf cuam tshuam hauv kev daws teeb meem tso fluoride ions, uas ua raws li nucleophiles hauv ntau yam tshuaj lom neeg. Cov tshuaj fluoride no tuaj yeem cuam tshuam lwm cov pab pawg Halogen (ua rau muaj cov pab pawg ntawm cov {}}}} f) b) b) b).
Sn2 Reviews: Fluorination siv Tmaf feem ntau tau ua los ntawm SN2 (bimolecular nucleophism carbon, tsis txhob sib sau cov pab pawg tshiab thiab ua ib daim ntawv cog lus tshiab.
Ruaj khov: Qhov sib txuam ntawm cov tshuaj fluorine atoms rau cov molecules tuaj yeem ua rau lawv cov tshuaj ruaj khov. Cov tshuaj fluorinated feem ntau tiv taus hydrolysis, oxidation, thiab lwm txoj hauv kev tsis zoo.
Lipophilicity: Fluorine atoms tuaj yeem txhim kho cov lipophilicity (rog solubility (uas muaj txiaj ntsig zoo rau kev txhim kho lawv cov xyoob ntoo thiab cov membrane permeability. Cov cuab yeej no yog qhov tshwj xeeb tshaj plaws hauv cov tshuaj tsim tshuaj, qhov twg lipophilic tshuaj tuaj yeem hla tau yooj yim dua cell weepraes mus cuag lawv cov chaw.
Metabolic tsis kam: Cov pa roj fluorinated feem ntau tiv taus cov teeb meem tsis txaus ntseeg los ntawm cov enzymes hauv lub cev. Qhov no tuaj yeem nthuav ib nrab ntawm - lub neej ntawm cov tshuaj, txo qhov zaus ntawm kev noj tshuaj thiab txhim kho tus neeg mob ua raws.
Tshuaj Kho Mob Tshuaj: Tmaf yog siv nyob rau hauv cov synthesis ntawm ntau cov khoom sib xyaw, suav nrog cov tshuaj tua kab mob, tshuaj tua kab mob, thiab anticancer cov neeg sawv cev. Piv txwv li, cov lus qhia txog cov tshuaj fluorine tuaj yeem txhim kho cov tshuaj thiab xaiv cov tshuaj, ua kom txhim kho cov txiaj ntsig zoo.
Prodrug synftesis: Fluorinated Prodrugs tuaj yeem tsim los txhim kho kev xa khoom thiab kev ua tau zoo ntawm cov khoom xyaw ua haujlwm. Cov tshuaj fluoride ion tuaj yeem muab tso rau kev hloov kho cov tshuaj cov tshuaj uas pharmackas.
Fluorinated intermediates: TMAF yog siv los ua hluavtaws cov fluorinated cov bluorinated block, uas yog qhov tseem ceeb rau kev tsim kho ntawm cov qauv molecules. Cov blocks lub tsev no tuaj yeem siv rau hauv synthesis ntawm cov synthesis ntawm cov synthesis ntawm cov polymers, agrochemicals, thiab cov khoom siv nrog cov khoom tshwj xeeb.
Ua hauj lwm pab pawg sib xyaw: Tmaf yog sib haum nrog ntau pab pawg ua haujlwm, tso cai rau kev fluorination ntawm cov nyom ntawm cov khoom siv sab nraud.
Tej Yam Yuav Mob Me: TMAF feem ntau tso cai rau cov tshuaj fluorination tau raug coj tawm hauv cov neeg muaj mob fluorinating rau nws cov tshuaj fluorinating (hf) lossis cov poov tshuaj fluoride (KF). Qhov no txo qis kev pheej hmoo ntawm cov kev phiv tshuaj thiab txhim kho cov txiaj ntsig tag nrho thiab kev coj dawb huv ntawm cov khoom xav tau.
Yooj yim ntawm kev kov: Tmaf yog yooj yim los lis thiab khaws piv rau gaseous lossis corrosive fluorinating cov neeg sawv cev fluorinating. Nws daim ntawv Tetranlyydrate tshwj xeeb yog qhov tshwj xeeb thiab tuaj yeem siv rau ntau yam ntawm cov kuab tshuaj.
6. Kev Kawm Txog Cov Ntaub Ntawv thiab Piv Txwv
Fluorinated tshuaj: Muaj ntau cov tshuaj ua lag luam muaj cov tshuaj fluorine qhia siv tmaf lossis reagents zoo sib xws. Piv txwv li, cov tshuaj anticancer (5-fu) yog cov tshuaj lom neeg fluorinated uracil, uas inhibits qhov hluav taws xob ntawm DNA thiab RNA hauv cov qog nqaij hlav cancer.
Fluorinated agnochemicals: Tmaf yog siv nyob rau hauv synthesis ntawm fluorinated tshuaj tua kab thiab cov tshuaj tua kab, ib puag ncig ruaj ntseg piv rau lawv tsis {{{{}} fluorinated counterparts.
|
|
|
Cag qaug zog
TMAF ua raws li lub hauv paus tsis muaj zog hauv cov organ reactionမ်းကatingດ, nrog rau nucleophilic hloov, thiab ntiv nplhaib {{}} qhib polymerizations.
Sn2 Reviews: Tmaf, raws li ib lub hauv paus ntawm cov tshuaj fluoride, tuaj yeem koom nrog SN2 (bimolecular nucleophilic hloov chaw) kev tawm tsam. Lub fluoride ion, ua ib pawg muaj zog muaj zog, tuaj yeem cuam tshuam lwm cov pab pawg ntawm cov kab mob {}} Cov tsiaj fluorine tshiab.
Cov lus thuam: Tmaf tseem tuaj yeem pab txhawb nucleophilic aromatic hloov (SNAR) cov tshuaj tiv thaiv. Hauv cov kev cuam tshuam no, cov tshuaj fluoride ion tawm tsam cov tsos uas muaj ntxhiab tsw qab, hloov cov pab pawg tawm thiab qhia txog cov tshuaj fluorine atom.
Silyl ether tas li: Tmaf tuaj yeem siv los tshem cov pob zeb tiv thaiv cov pab pawg ntawm cov pab pawg hydroxyl. Qhov no muaj txiaj ntsig zoo tshwj xeeb nyob rau hauv synthesis ntawm cov organic molecules uas cov pab pawg hydroxyl yuav tsum tau ua ib ntus ib pawg thiab tom qab ntawd unmasked ntawm ib theem tom qab.
Lwm Pawg Tiv Thaiv: Tmaf tseem tuaj yeem siv los tshem tawm lwm cov kua qaub - Labile tiv thaiv pab pawg, xws li Esters thiab Acetals, nyob rau hauv cov mob me.
O {- carboxyanhydrides (OCAS): Tmaf tau raug siv los ua catalyst rau lub nplhaib {{}}}}}-} carboxyanhydrides. Cov polymerization no tuaj yeem tsim cov polyestters nrog ntau pawg neeg ua haujlwm, uas yog ib pawg neeg ua haujlwm nyuaj kom tau los ntawm polymerization ntawm lactones.
Lub tshuab: Raws li lub hauv paus tsis muaj zog, TMAF tuaj yeem ua kom lub OCA monomer, pib lub nplhaib {{}}}} qhib polymerization txheej txheem. Qhov kev sib ze sib thooj ntawm cov pab pawg ua haujlwm hauv TMAF cov koom tes muaj cov nyhuv synergetic zoo, tso cai rau kev siv cov pa roj me thiab ua kom tsawg thaum lub zog polymerization.
Cov mob me me: Tmaf tso cai rau kev hloov tshuaj lom neeg yuav tsum tau ua raws li cov neeg muaj zog hauv lub hauv paus piv rau cov hauv paus kom muaj zog dua. Qhov no txo qis kev pheej hmoo ntawm cov kev phiv tshuaj thiab txhim kho cov txiaj ntsig tag nrho thiab kev coj dawb huv ntawm cov khoom xav tau.
Ua hauj lwm pab pawg sib xyaw: Tmaf yog sib xws nrog ntau pab pawg ua haujlwm, ua rau nws haum rau cov synthesis ntawm cov organic molecules tsis muaj qhov ua rau tsis muaj kev xav tsis zoo.
Yooj yim ntawm kev kov: Lub TetranlyYdrate Daim Ntawv ntawm TMAF yog qhov ruaj khov dua thiab yooj yim dua muab piv rau lwm lub hauv paus uas tsis muaj zog, ua rau nws nyiam tshaj plaws hauv ntau cov organic syntherfories.
Kws Tshuaj: Tmaf lub peev xwm los pab txhawb nucleophilic hloov cov pab pawg thiab ua haujlwm pab pawg tsis txaus siab tshwj xeeb hauv cov hluavtaws ntawm cov tshuaj sib xyaw. Piv txwv li, nws tuaj yeem siv los qhia cov tshuaj fluorine atoms rau hauv cov yeeb tshuaj molecules, txhim kho lawv cov potency thiab metabolic ruaj khov.
Agnchemicals: Tmaf kuj tau siv nyob rau hauv cov synthesis ntawm agrochemicals, xws li tshuaj tua kab thiab cov tshuaj tua kab. Nws lub peev xwm tshem tawm cov pab pawg tiv thaiv thiab lub rooj saib xyuas num thiab kub}
Cov ntaub ntawv kawm txuj ci: Hauv cov ntaub ntawv kev tshawb fawb, TMAF tuaj yeem siv los ua hluavtaws cov tshuaj lom fluorinated thiab nanomaterials nrog cov khoom muaj zog, xws li cov tshuaj tsis tshua muaj zog.
Lub Tetramethylammonium Fluoride Tetrahydate(Tmaf · 43o) tau tawm los ua cov txheej txheem tseem ceeb hauv thaj chaw cov organic chemistry, tshwj xeeb hauv cov txheej txheem hluavtaws thiab catalictic. Nws cov keeb kwm kev tshawb fawb keeb kwm tsom kho nws qhov tseem ceeb tshaj plaws thiab versatility.
Tesaf · 4Ch2O yog ib tug Quandary ammonium ntsev uas ua rau lub zog tsis muaj zog thiab cov tshuaj fluoride. Nws yog lub npe hu rau nws tau compatibility nrog ntau pab pawg ua haujlwm, ua rau nws muaj ntau pawg ua haujlwm nyob rau hauv cov khoom siv tshuaj schiset. Kev tshawb fawb thaum ntxov tau hais txog nws txoj kev siv ua lub tshuaj fluorinating hauv cov tshuaj chemistry, qhov uas nws tau ua haujlwm hauv kev npaj cov lag luam tawm cov leeg ua haujlwm thiab cov protein hloov hauv Biochemistry.
Ib qho tseem ceeb hauv kev tshawb fawb hauv kev tshawb fawb ntawm TMAF- scale ntau lawm fluorinated heterocyclic aromatics. Hauv kev kawm ua ke tau tshaj tawm los ntawm Hefei Kws Tshuaj thiab Eli Lilly thiab tuam txhab, cov kws tshawb nrhiav tau tsim ib txoj kev kom tau muaj tsib- cov tshuaj fluorints. Qhov kev sib tsoo no hais txog cov kev txwv ntawm anhydrous tmaf, uas, thaum ua haujlwm zoo, nyuaj kom tau txais hauv cov khoom lag luam.
Qhov kev tshawb fawb pom tias Tocaf {2, tuaj yeem siv tau zoo thiab muaj peev xwm siv tau kev nyab xeeb thiab muaj txiaj ntsig} cov tshuaj tiv thaiv zoo li, xws li kev tsim cov tshuaj lom 4 ntawm cov tshuaj lom neeg. Qhov haujlwm no tsis yog tsuas yog txo cov nqi roj raw tab sis tseem siv cov ntsuas scalability ntawm tmaf · 4H2o rau kev siv cov ntawv thov.
Tsis tas li ntawd xwb, Tmaf · 4 'tau kawm rau nws lub luag haujlwm yog theem hloov catalyst hauv cov synthic synthesis. Nws lub peev xwm los pab txhawb cov kev tawm tsam ntawm cov theem impriscible tau siv hauv ntau cov kev ntsuas catalytic, txhim kho cov tshuaj tiv thaiv thiab qoob loo. Piv txwv li, nws tau siv los txhim kho cov kev ua haujlwm ntawm cov carbon dioxide thiab epoxides, txhawb nqa cov pa roj carbon dioxide rau hauv cov ntaub pua av polymer.
Kev tshawb fawb txuas ntxiv txuas ntxiv mus tshawb cov ntawv thov tshiab thiab cov txheej txheem hluavtaws muaj kev cuam tshuam nrog TMAF · 4HHT2O. Nws cov ruaj khov, yooj yim ntawm kev tuav, thiab kev sib xyaw nrog ntau pawg ua haujlwm ua rau nws muaj kev tshawb fawb txaus nyiam rau kev kawm thiab kev tshawb fawb. Raws li qhov kev thov kom muaj txiaj ntsig zoo thiab muaj kev lom zem hluavtaws loj hlob, TMAF increasing increasing important important important important Ercounds thiab cov ntaub ntawv.
Cim npe nrov: Tetramethilmonium fluoride CASE 17787-40-5, Tuam Tshoj chaw tsim khoom, chaw tsim khoom, yuav khoom, khoom, loj, rau muag