Yog tias koj tab tom txiav txim siab nojlinaclotide rau koj cov teeb meem plab hnyuv, tej zaum koj yuav xav txog ib puag ncig muaj feem cuam tshuam, suav qhov hnyav nce.
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nkag siab liancoltide: nws yog dab tsi thiab nws ua haujlwm li cas?
Linaclotide, muag hauv qab cov npe xws li Linzess thiab Constella, yog cov tshuaj siv los kho cov kev cuam tshuam tsis tu ncua thiab tsis zoo rau lub plab zom mov nrog kev tsis txaus siab (IBS-C). Nws ua haujlwm los ntawm kev nthuav tawm cov kua dej tawm hauv lub cev thiab ua kom lub plab zom mov sai, muab kev txo qis rau cov kev tawm tsam nrog cov xwm txheej no.
Kev kho kom zoo nyob rau hauv linaclotide yog ib qho 14-amino corrosive peptide uas ua rau cov guanylate cyclase-C receptor nyob rau ntawm qhov chaw luminal ntawm txoj hnyuv epithelium. Qhov kev cai lij choj no ua rau nthuav tawm cov kua hauv plab hnyuv thiab nrawm mus ncig, uas ua rau muaj qhov sib txawv txo cov tsos mob nres.
Linaclotide feem ntau noj ib zaug ib hnub rau ntawm lub plab huv si, ntawm me ntsis 30 feeb qee lub sij hawm tsis ntev los no pib noj hmo ntawm ib hnub. Nws yog ib qho tseem ceeb uas yuav tau ua tib zoo saib xyuas koj tus kws kho mob cov ntaub ntawv thaum noj cov tshuaj no.
linaclotide thiab qhov hnyav: lsolating qhov tseeb los ntawm cov ntawv tseeb
Tam sim no, cia peb hais qhov chaw nyob tseem ceeb: puaslinaclotideua rau hnyav nqa? Cov lus teb luv luv yog tsis yog, linaclotide tsis yog feem ntau cuam tshuam nrog qhov hnyav nce. Nyob rau hauv qhov tseeb, qhov hnyav nce tsis tau sau tseg raws li ib qho kev cuam tshuam ntawm cov tshuaj no hauv kev sim tshuaj lossis kev tshaj tawm tom qab kev lag luam.
Nov yog ob peb lub ntsiab lus tseem ceeb los txiav txim siab kwv yees li linaclotide thiab qhov hnyav:
Tsis muaj kev sib koom tes sib txuas kom hnyav nqa
Kev txiav txim siab kho mob tsis tau tshwm sim muaj kev sib raug zoo ntawm linaclotide siv thiab hnyav tuaj. Qhov tseeb tiag, ob peb tus neeg mob tuaj yeem koom nrog qhov hnyav me ntsis vim kev nthuav dav hauv plab hnyuv.
Muaj peev xwm rau luv luv qhov sib txawv
Raws li linaclotide cuam tshuam cov kua emissions nyob rau hauv sab hauv, koj yuav tau nco ntsoov me me qhov hnyav vacillations vim muaj kev hloov hauv cov kua hloov. Ua li ntawd, cov no feem ntau hloov pauv thiab tsis yog yam ntxwv ntawm qhov hnyav nce.
Txhim kho plab ntsig txog kev noj qab haus huv
Los ntawm lightening clogging, linaclotide tuaj yeem muab kev pab txo qis plab thiab plab tsis yooj yim, uas tej zaum yuav ua rau lub plab qhuas thiab pom qhov hnyav hnyav hauv ob peb tus neeg.
Nws tsim nyog pom tias qhov twg linaclotide nws tus kheej tsis ua rau qhov hnyav nce, lwm yam cuam tshuam rau koj lub plab ntsig txog kev noj qab haus huv lossis kev hloov pauv ntawm lub neej zoo li cuam tshuam koj qhov hnyav. Txuas ntxiv nrog koj tus kws kho mob tham yog tias koj muaj kev txhawj xeeb yuav luag hloov pauv thaum noj tshuaj.
Cov kev mob tshwm sim feem ntau thiab xav txog thaum noj linaclotide
Thaum qhov hnyav nce tsis yog ib qho kev txhawj xeeb nroglinaclotide, Nws yog ib qho tseem ceeb kom paub txog lwm yam kev mob tshwm sim thiab kev txiav txim siab:
Cov teebmeem tshwm sim
Feem ntau cov kev mob tshwm sim ntawm linaclotide muaj xws li:
Mob plab
Mob plab
Flatulence (gas)
plab hnyuv
Mob taub hau
Cov kev mob tshwm sim no feem ntau yog me me mus rau nruab nrab thiab feem ntau txhim kho thaum koj lub cev hloov kho rau cov tshuaj. Txawm li cas los xij, yog tias koj muaj kev mob tshwm sim hnyav los yog tsis tu ncua, nws tseem ceeb heev kom tiv tauj koj tus kws kho mob.
Kev txiav txim siab tshwj xeeb
Thaum noj linaclotide, nco ntsoov cov hauv qab no:
Kev pheej hmoo ntawm lub cev qhuav dej: Vim muaj cov kua dej ntau ntxiv hauv cov hnyuv, muaj peev xwm ua rau lub cev qhuav dej, tshwj xeeb tshaj yog tias koj muaj raws plab. Xyuas kom koj haus dej ntau thaum noj linaclotide.
Kev cuam tshuam nrog lwm cov tshuaj: Thaum linaclotide muaj qee qhov kev sib cuam tshuam ntawm cov tshuaj, nws yog ib qho tseem ceeb kom qhia rau koj tus kws kho mob txog txhua yam tshuaj, tshuaj, thiab tshuaj ntsuab uas koj noj.
Cev xeeb tub thiab pub niam mis: Kev nyab xeeb ntawm linaclotide thaum cev xeeb tub thiab pub niam mis tsis tau tsim. Nrog koj tus kws kho mob tham yog tias koj cev xeeb tub, npaj yuav cev xeeb tub, lossis pub niam mis.
Siv rau cov menyuam yaus: Linaclotide tsis pom zoo siv rau cov menyuam yaus hnub nyoog qis dua 18 xyoo vim muaj kev txhawj xeeb txog kev nyab xeeb.
Saib xyuas Koj Kev Noj Qab Haus Huv Thaum nyob ntawm Linaclotide
Thaum noj linaclotide, nws tseem ceeb heev rau:
Ua raws li koj cov tsos mob thiab txhua yam kev mob tshwm sim uas koj tau ntsib
Saib xyuas kev kuaj mob tsis tu ncua nrog koj tus kws kho mob
Qhia txog kev hloov pauv tseem ceeb hauv koj qhov kev noj qab haus huv lossis qhov hnyav
Ua raws li kev noj zaub mov kom zoo thiab nyob twj ywm hydrated
Koom nrog kev ua si lub cev tsis tu ncua raws li koj tus kws kho mob pom zoo
Nco ntsoov, txhua tus neeg lub cev ua haujlwm txawv rau cov tshuaj. Dab tsi ua haujlwm zoo rau ib tus neeg yuav tsis zoo rau lwm tus. Nws yog ib qho tseem ceeb uas yuav tau ua hauj lwm nrog koj tus kws kho mob kom nrhiav tau txoj kev kho mob zoo tshaj plaws rau koj tus kheej xav tau.
xaus
Hauv kev xaus, thaum lo lus nug "Puas linaclotide ua rau hnyav nce?" yog ib qho kev txhawj xeeb uas siv tau, cov pov thawj tam sim no qhia tias qhov hnyav nce tsis yog qhov tshwm sim ntawm cov tshuaj no. Linaclotide feem ntau tsom rau kev txhim kho digestive noj qab haus huv los ntawm alleviating constipation thiab IBS-C cov tsos mob.
Yog tias koj raug tshuaj linaclotide, tsom ntsoov rau nws cov txiaj ntsig zoo rau koj txoj kev noj qab haus huv es tsis txhob txhawj txog qhov hnyav. Txawm li cas los xij, ib yam li txhua yam tshuaj, nws yog ib qho tseem ceeb los saib xyuas koj txoj kev noj qab haus huv tag nrho, suav nrog koj qhov hnyav, thiab sib txuas lus nrog koj tus kws kho mob.
Nco ntsoov, kev tswj hwm txoj kev noj qab haus huv nrog kev noj zaub mov zoo thiab kev tawm dag zog tsis tu ncua tuaj yeem ua rau muaj txiaj ntsig zoo rau koj txoj kev noj qab haus huv tag nrho, suav nrog kev noj qab haus huv hauv plab. Linaclotide, thaum siv raws li qhia, tuaj yeem yog ib qho cuab yeej zoo hauv kev tswj hwm cem quav thiab IBS-C, uas tuaj yeem txhim kho koj lub neej zoo.
Yog koj muaj lus nug txoglinaclotidelossis lwm yam kev kho mob rau kev zom zaub mov, tsis txhob yig hu mus rau koj tus kws kho mob. Lawv tuaj yeem muab cov lus qhia tus kheej raws li koj tus kheej xav tau kev noj qab haus huv thiab kev txhawj xeeb.
Yog xav paub ntxiv, koj tuaj yeem hu rau lawv ntawmSales@bloomtechz.com.
cov ntaub ntawv
Chey, WD, Lembo, AJ, & Lavins, BJ (2012). Linaclotide rau Irritable bowel Syndrome nrog cem quav: A 26-Lub lim tiam, Randomized, Ob qhov muag tsis pom kev, Kev sim tshuaj placebo los ntsuas kev ua tau zoo thiab kev nyab xeeb. American Journal of Gastroenterology, 107(11), 1702-1712.
Lacy, BE, Levenick, JM, & Crowell, MD (2012). Linaclotide: Ib qho Kev Xaiv Tshiab rau Kev Kho Mob Ntawm Cov Kab Mob Hlwb Kab Mob nrog cem quav thiab cem quav idiopathic rau cov neeg laus. Gastroenterology & Hepatology, 8(9), 624-627.
US Food and Drug Administration. (2012). Linzess (linaclotide) capsules, rau kev siv qhov ncauj. Tau txais los ntawm https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202811lbl.pdf
Rao, S., Lembo, AJ, Shiff, SJ, Lavins, BJ, Currie, MG, Jia, XD, ... & Johnston, JM (2012). Ib 12-lub lim tiam, randomized, tswj kev sim nrog rau 4-lub lim tiam randomized tshem tawm lub sij hawm los soj ntsuam kev ua tau zoo thiab kev nyab xeeb ntawm linaclotide nyob rau hauv chim siab plob tsis so tswj syndrome nrog cem quav. American Journal of Gastroenterology, 107(11), 1714-1724.
Videlock, EJ, Cheng, V., & Cremonini, F. (2013). Cov teebmeem ntawm Linaclotide hauv cov neeg mob uas mob plab hnyuv plab nrog cem quav lossis cem quav ntev: Kev tshuaj xyuas Meta. Clinical Gastroenterology thiab Hepatology, 11(9), 1084-1092.