4-Bromobenzotrifluorideyog lub pob tshab rau cov kua xim av nrog cov ntxhiab tsw tshwj xeeb me ntsis. Cov mis mos molecular C7H4BrF3, CAS402-43-7. Tsis yooj yim volatile ntawm chav tsev kub thiab siab. Ib qho yooj yim rau yaj hauv dej thiab concentrated poov tshuaj sulfate tov, yuav luag insoluble hauv ethanol. Nws yog ib qho ruaj khov ntawm chav tsev kub thiab siab, thiab tsis muaj tshuaj lom neeg. Nws muaj qee qhov qib ntawm sublimation thiab tuaj yeem sublimate thaum rhuab. Nws muaj crystallinity siab thiab yog ib qho yooj yim los tsim cov muaju. Nws yog ib qho tseem ceeb nruab nrab ntawm cov organic synthesis thiab tuaj yeem siv los ua ke lwm cov organic sib txuas. Los ntawm reacting nrog sib txawv reactants, ib tug series ntawm cov tebchaw nrog ib tug tshwj xeeb cov qauv thiab cov khoom muaj peev xwm raug synthesized, uas yog siv nyob rau hauv teb xws li tshuaj, tshuaj tua kab, dyes, thiab lwm yam. Muaj ntau yam kev siv nyob rau hauv oilfield chemicals, nrog rau cov synthesis ntawm oilfield additives, roj. Cov neeg ua haujlwm rov qab, cov tshuaj kho cov dej-dej, cov khoom siv roj av preservatives, thiab cov kua dej ntxiv ntxiv. Cov tshuaj no ua lub luag haujlwm tseem ceeb hauv oilfield extraction thiab roj av kev lag luam, pab txhim kho cov extraction efficiency, txo nqi, tiv thaiv cov cuab yeej thiab ib puag ncig, thiab lwm yam.
(Cov khoom txuas: https://www.bloomtechz.com/synthetic-chemical/organic-intermediates/4-bromobenzotrifluoride-cas-402-43-7.html)
Txoj kev sulfonation amination yog ib txoj hauv kev siv los ua ke ntawm 4-Bromobenzotrifluoride. Cov hauv qab no yog cov kauj ruam ntxaws ntxaws thiab sib npaug ntawm cov tshuaj sib npaug:
1. Cov tshuaj tiv thaiv bromination
Cov tshuaj tiv thaiv bromination yog ib kauj ruam tseem ceeb hauv kev hloov pauv ntawm 4-iodobenzene rau 4-bromobenzene. Cov kauj ruam no feem ntau yog ua raws li catalysis ntawm anhydrous aluminium chloride lossis hlau hmoov. 4-iodobenzene (C6H5I) reacts nrog bromine (Br2) los tsim 4-bromobenzene (C6H4Br).
Chemical equation: C6H5I+Br2 → C6H4Br+HBr
2. Cov tshuaj tiv thaiv sulfonation
Nyob rau hauv qhov kev txiav txim ntawm cov concentrated sulfuric acid, 4-bromobenzene reacts nrog hydrogen ions nyob rau hauv cov kua qaub tov los tsim 4-nitrobromobenzene (C6H4BrNO2).
Chemical equation: C6H4Br+HNO3+H2SO4 → C6H4BrNO2+H2O
3. Txo cov tshuaj tiv thaiv
Nyob rau hauv qhov kev txiav txim ntawm kev txo cov neeg ua hauj lwm xws li hlau hmoov, hydrazine hydrate, sodium sulfide, thiab lwm yam., 4-nitrobromobenzene txo mus rau 4-aminobromobenzene (C6H4BrNH2).
Chemical equation: C6H4BrNO2+txo tus neeg sawv cev → C6H4BrNH2+ khoom
4. Diazotization cov tshuaj tiv thaiv
Raws li kev ua ntawm sodium nitrite (NaNO2), 4-aminobromobenzene cov ntaub ntawv diazonium ntsev.
Chemical equation: C6H4BrNH2+NaNO2 → diazonium ntsev + NaBr
5. Cov tshuaj tiv thaiv fluorination
Diazo ntsev reacts nrog hydrogen fluoride (HF) los tsim 4-fluorobenzenesulfonic acid (C6H3FSO3H).
Kev sib npaug tshuaj: diazonium ntsev + HF → C6H3FSO3H + N2
6. Amination cov tshuaj tiv thaiv
Raws li kev ua ntawm ammonia (NH3), 4-fluorobenzenesulfonic acid hloov mus rau 4-aminobenzenesulfonamide (C6H5SO2NHNH2). Cov kauj ruam no tseem tuaj yeem hloov cov ammonia nrog lwm cov tshuaj amine, xws li methylamine, ethylamine, thiab lwm yam.
Chemical equation: C6H3FSO3H+NH3 → C6H5SO2NHNH2+H2O
7. Rearrangement cov tshuaj tiv thaiv
Nyob rau hauv cov cua kub cua sov, 4-aminobenzenesulfonamide tau txais cov tshuaj tiv thaiv rov qab los tsim cov khoom lag luam hom phiaj 4-Bromobenzotrifluoride (C6H3BrF3). Cov tshuaj tiv thaiv no tseem hu ua Fischer Tropsch rearrangement.
Chemical equation: C6H5SO2NHNH2 → C6H3BrF3+H2SO3
Los ntawm xya kauj ruam saum toj no, 4-Bromobenzotrifluoride tuaj yeem ua tiav los ntawm txoj kev sulfonation amination. Tag nrho cov txheej txheem suav nrog ntau hom tshuaj tiv thaiv, suav nrog halogenation, sulfonation, txo qis, diazotization, fluorination, thiab rov kho dua. Kev sib xyaw ua ke thiab ua ntu zus ntawm cov tshuaj tiv thaiv no ua haujlwm ua ke kom ua tiav qhov kev sib txuas ntawm cov khoom lag luam. Hauv kev ua haujlwm zoo, nws yog ib qho tsim nyog yuav tsum nruj me ntsis tswj cov kev mob tshwm sim, xws li kub, acidity, lub sij hawm, thiab lwm yam, kom ntseeg tau tias purity thiab tawm los ntawm cov khoom. Lub caij no, rau qee yam tshuaj lom neeg thiab kev ua haujlwm, kev ntsuas kev nyab xeeb yuav tsum tau coj los ua kom muaj kev nyab xeeb ntawm cov neeg ua haujlwm sim.
Bromination yog ib txoj hauv kev uas feem ntau siv rau kev sib txuas ntawm 4-Bromobenzotrifluoride. Cov hauv qab no yog cov kauj ruam ntxaws ntxaws thiab sib npaug ntawm cov tshuaj sib npaug:
1, Cov tshuaj tiv thaiv bromination
Cov tshuaj tiv thaiv bromination yog ib kauj ruam tseem ceeb hauv kev hloov pauv ntawm 4-iodobenzene rau 4-bromobenzene. Cov kauj ruam no feem ntau yog ua raws li catalysis ntawm anhydrous aluminium chloride lossis hlau hmoov. 4-iodobenzene (C6H5I) reacts nrog bromine (Br2) los tsim 4-bromobenzene (C6H4Br).
Chemical equation: C6H5I+Br2 → C6H4Br+HBr
2, Fluorination tshuaj tiv thaiv
Raws li kev ua ntawm hydrogen fluoride, 4-bromobenzene hloov mus rau 4-fluorobenzene.
Chemical equation: C6H4Br+HF → C6H4F+HBr
3, Sulfonation cov tshuaj tiv thaiv
Nyob rau hauv qhov kev txiav txim ntawm concentrated sulfuric acid, 4-fluorobenzene reacts nrog hydrogen ions nyob rau hauv cov kua qaub tov los tsim 4-fluorobenzenesulfonic acid.
Chemical equation: C6H4F+HNO3+H2SO4 → C6H4FSO3H+H2O
4, Nitrification cov tshuaj tiv thaiv
Raws li kev ua ntawm cov concentrated nitric acid, 4-fluorobenzenesulfonic acid hloov mus rau 4-nitrofluorobenzenesulfonic acid.
Chemical equation: C6H4FSO3H+HNO3 → C6H4FSO2NO2+H2O
5, Hydrolysis cov tshuaj tiv thaiv
Raws li kev ua ntawm sodium hydroxide, 4-nitrofluorobenzenesulfonic acid yog hydrolyzed los tsim 4-nitroaniline.
Chemical equation: C6H4FSO2NO2+2NaOH → C6H4NH2SO3Na+NaNO2+NaF+2H2O
6, Diazotization cov tshuaj tiv thaiv
Raws li kev ua ntawm sodium nitrite, 4-nitroaniline hloov mus rau diazonium ntsev.
Chemical equation: C6H4NH2SO3Na+NaNO2 → C6H4NSO2Na+N2
7, Txo cov tshuaj tiv thaiv
Nyob rau hauv qhov kev txiav txim ntawm hydrogen, diazonium ntsev yog txo kom coj cov amino ntsev.
Chemical equation: C6H4NSO2Na+3H2 → C6H4NH3+NaHS+3H2O
8, Salinization tshuaj tiv thaiv
Amino ntsev teb nrog cov kua qaub los tsim cov khoom lag luam. Vim lub fact tias cov amino pawg yog alkaline pab pawg neeg, lawv undergone neutralization cov tshuaj tiv thaiv nrog acids, ua coj cov ntsev thiab dej. Hauv cov txheej txheem no, qee qhov kev kho mob tom ntej xws li decolorization thiab desalination yog xav tau los xyuas kom meej qhov purity thiab zoo ntawm cov khoom.
Chemical equation: C6H4NH3+HX → C6H3 (X) NH2+H2O, qhov twg X sawv cev rau cov kua qaub ions.