Taw qhia
Nyob rau hauv lub ntiaj teb no ntawm kev kho mob antiviral,TIAB SA 441524tau tshwm sim los ua ib qho tseem ceeb, tshwj xeeb tshaj yog rau nws lub peev xwm los kho qee yam kab mob hauv miv, suav nrog feline infectious peritonitis (FIP). Qhov blog no lub hom phiaj los muab cov lus qhia dav dav rauGS441524 hmoov, suav nrog nws cov khoom, yuav ua li cas kom tau nws, thiab nws cov ntawv thov. Peb yuav tshawb nrhiav cov kauj ruam tsim nyog kom tau txais GS 441524, delve rau hauv nws cov kev siv, thiab muab cov ntaub ntawv tseem ceeb rau cov kws tshawb fawb thiab kws kho tsiaj. Cia peb dhia dej!
GS 441524 yog dab tsi?
Txheej txheem cej luam ntawm GS 441524
GS 441524 yog ib qho nucleoside analog, zoo ib yam li cov tshuaj tiv thaiv kab mob uas muaj npe nrov remdesivir. Nws tau pom tias muaj txiaj ntsig zoo hauv kev kho mob kis kab mob, tshwj xeeb tshaj yog feline infectious peritonitis (FIP), kab mob tuag taus hauv miv los ntawm qee hom kab mob feline coronavirus.
Lub npe tshuaj: 4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2- yl]-1H-pyrrolo[2,{13}}f][1,2,4]triazin-5-ib
Cov roj formula: C12H13N5O4
Molecular Luj: 291.26 g / mol
Properties thiab Mechanism of Action
GS 441524 ua haujlwm los ntawm inhibiting replication ntawm tus kab mob RNA, yog li txo cov kab mob hauv cov kab mob. Nws cuam tshuam nrog tus kab mob RNA-dependent RNA polymerase, ib qho enzyme tseem ceeb rau kev rov ua dua ntawm cov kab mob RNA.
Kev Tiv Thaiv Kab Mob: Siv tau rau ntau yam kabmob coronaviruses, suav nrog cov uas ua rau FIP hauv miv.
Kev Nyab Xeeb Profile: Feem ntau ua tau zoo nyob rau hauv cov tsiaj, muaj kev phiv tsawg dua piv rau lwm cov tshuaj tiv thaiv kab mob.
Yuav Ua Li Cas Tau Txais GS 441524
Kev yuav khoom los ntawm Reputable Suppliers
Tau txais GS 441524 suav nrog kev yuav khoom los ntawm cov chaw muag khoom muaj npe uas tshwj xeeb hauv kev muab cov tshuaj zoo tshaj plaws.
Cov neeg muab kev tshawb fawb: txheeb xyuas cov neeg muag khoom nrog lub koob npe zoo thiab cov ntaub ntawv pov thawj hauv kev muab cov tshuaj-qib sib txuas. Nrhiav cov ntawv pov thawj thiab cov neeg siv khoom tshuaj xyuas.
Xyuas kom huv huv: Xyuas kom GS 441524 muaj qib purity siab (feem ntau tshaj 98%) kom ntseeg tau tias muaj txiaj ntsig thiab kev nyab xeeb.
Tshawb xyuas Cov Cai: Nkag siab txog cov cai lij choj hauv koj lub tebchaws hais txog kev yuav khoom thiab siv GS 441524. Qee thaj tsam yuav muaj kev txwv lossis xav tau kev tso cai tshwj xeeb.
Hu rau Shaanxi BLOOM TECH Co., Ltd
Ntawm Shaanxi BLOOM TECH Co., Ltd, peb tshwj xeeb hauv kev muab cov khoom zooGS441524 hmoov. Peb cov khoom yog tsim nyob rau hauv ib tug koom tes GMP ntau lawm site, kom ntseeg tau raws li US, EU, JP, thiab CFDA GMP qauv.
Cov ntaub ntawv tiv tauj: Rau kev nug thiab kev yuav khoom, hu rau peb. Peb pab neeg yuav pab koj nrog cov ntsiab lus ntawm cov khoom, tus nqi, thiab cov ntaub ntawv xa khoom.
Lub hom phiaj ntawm Chain Sprockets
Metric Roller Chain Sprocket tuaj yeem siv tau rau hauv yuav luag txhua hom kab ke. Siv rau hauv cov tshuab conveyor xws li conveyors, nws tuaj yeem thauj khoom noj, dej haus, nplej, thiab lwm yam khoom siv los ntawm ib qho chaw mus rau lwm qhov. Siv nyob rau hauv kev sib kis kab mob, nws hloov lub zog los ntawm ib qho chaw xws li lub cav mus rau ntau yam khoom xws li lub log. Yog li, cov khoom lag luam kuj tau siv dav hauv kev lag luam xws li kev tsim tshuab, khoom siv ua liaj ua teb, tsheb, thiab khoom siv tub rog.
Nkag siab txog kev txiav txim siab txog kev cai lij choj thiab kev ncaj ncees
Ua ntej yuav thiab siv GS 441524, nws yog ib qho tseem ceeb uas yuav tau xav txog qhov cuam tshuam txog kev cai lij choj thiab kev coj ncaj ncees.
Raws li txoj cai: Txheeb xyuas cov xwm txheej raug cai ntawm GS 441524 hauv koj cheeb tsam. Qee qhov chaw yuav muaj kev cai nruj rau nws siv, tshwj xeeb tshaj yog rau kev siv tsiaj.
Ethical Use: Xyuas kom meej tias kev siv GS 441524 yog kev coj ncaj ncees, tshwj xeeb tshaj yog nyob rau hauv cov kws kho tsiaj. Tham nrog kws kho tsiaj thiab ua raws li cov lus pom zoo kom tsis txhob siv tsis raug.
Daim ntawv thov ntawm GS 441524 Powder
Kho Feline Infectious Peritonitis (FIP)
Ib qho ntawm cov kev siv tseem ceeb ntawm GS 441524 yog nyob rau hauv kev kho mob ntawm feline infectious peritonitis (FIP), kab mob phem heev hauv miv.
Nkag siab FIP
FIP yog tshwm sim los ntawm qee hom kab mob feline coronavirus uas hloov pauv thiab dhau los ua kab mob. Nws cuam tshuam rau ntau yam kabmob thiab feem ntau tuag yam tsis tau kho.
Cov tsos mob: Cov tsos mob muaj xws li kub taub hau, qaug zog, poob phaus, thiab cov kua dej hauv plab.
Kev kuaj mob: Kev kuaj mob yog qhov nyuaj thiab suav nrog kev sib xyaw ua ke ntawm kev kuaj mob, kev kuaj sim, thiab kev tshawb fawb pom.
Kev ua tau zoo ntawm GS 441524 hauv Kev Kho FIP
Cov kev tshawb fawb tau qhia tiasGS441524 hmoovmuaj txiaj ntsig zoo hauv kev kho FIP, ua rau muaj kev txhim kho tseem ceeb hauv cov tsos mob thiab kev muaj sia nyob.
Kev sim tshuaj kho mob: Ntau qhov kev sim tshuaj ntsuam xyuas tau pom qhov ua tau zoo ntawm GS 441524 hauv kev txo cov kab mob kis thiab txhim kho kev noj qab haus huv ntawm miv nrog FIP.
Kev Noj Qab Haus Huv thiab Kev Tswj Xyuas: Qhov ntau npaum thiab kev tswj hwm ntawm GS 441524 txawv raws li qhov hnyav ntawm tus kab mob thiab qhov hnyav ntawm tus miv. Nws feem ntau yog siv los ntawm kev txhaj tshuaj subcutaneous.
Kev tshawb fawb thiab kev loj hlob
GS 441524 kuj tseem muaj txiaj ntsig hauv kev tshawb fawb thiab kev tsim kho, tshwj xeeb hauv kev kawm txog kev kho tshuaj tiv thaiv kab mob thiab kev txhim kho tshuaj.
Kawm txog Antiviral Mechanisms
Cov kws tshawb fawb siv GS 441524 los kawm txog cov txheej txheem ntawm kev tiv thaiv kab mob thiab tsim kho tshiab rau kev kis kab mob.
RNA Viruses: GS 441524 yog siv nyob rau hauv kev tshawb fawb ntawm ntau yam kab mob RNA, muab kev nkag siab txog tus kab mob replication thiab inhibition.
Kev Txhim Kho Tshuaj: Cov khoom sib xyaw ua haujlwm ua qauv rau kev tsim cov tshuaj tiv thaiv kab mob tshiab nrog kev txhim kho kev ua tau zoo thiab kev nyab xeeb profile.
Daim ntawv thov hauv Human Medicine
Thaum GS 441524 feem ntau yog siv hauv cov tshuaj kho tsiaj, nws cov qauv zoo sib xws rau remdesivir ua rau nws muaj kev txaus siab rau tib neeg cov tshuaj ib yam nkaus.
Cov ntawv thov muaj peev xwm: Cov kws tshawb fawb tab tom tshawb nrhiav cov ntawv thov muaj peev xwm ntawm GS 441524 hauv kev kho cov kab mob tib neeg, suav nrog tus mob coronaviruses.
Kev Tshawb Fawb Sib Piv: Cov kev tshawb fawb sib piv ntawm GS 441524 thiab remdesivir pab kom nkag siab txog kev ua tau zoo thiab kev nyab xeeb ntawm ob qho tib si.
Kev nyab xeeb thiab tuav ntawm GS 441524 hmoov
Cia thiab tuav
Kev ruaj ntseg thiab kev tuav pov hwm zooGS441524 hmoovyog qhov tseem ceeb los tswj nws txoj kev ruaj ntseg thiab kev ua tau zoo.
Cia Lub Sijhawm: Khaws GS 441524 hauv qhov chaw txias, qhuav, deb ntawm tshav ntuj ncaj qha thiab ya raws. Siv cov thawv airtight los tiv thaiv kev sib kis.
Kev Tiv Thaiv Kev Tiv Thaiv: Hnav cov cuab yeej tiv thaiv tus kheej tsim nyog (PPE) xws li hnab looj tes, tsom iav, thiab cov tsho hauv chaw kuaj mob thaum tuav GS 441524. Tsis txhob hnov qab txog kev nqus ntawm daim tawv nqaij.
Kev Tiv Thaiv Kev Nyab Xeeb
Thaum GS 441524 feem ntau muaj kev nyab xeeb, ua raws li kev ceev faj txog kev nyab xeeb yog qhov tseem ceeb kom txo qis kev pheej hmoo.
Tsis txhob nqus pa: Siv lub fume hood los yog ua haujlwm hauv qhov chaw uas muaj cua zoo kom tsis txhob nqus cov pa GS 441524.
Tiv thaiv tawv nqaij: Hnav cov hnab looj tes tiv thaiv tawv nqaij thiab ntxuav tes kom huv si tom qab tuav.
Pov tseg: Pov tseg GS 441524 pov tseg raws li cov cai hauv zos thiab cov lus qhia. Tsis txhob muab nws tso rau hauv qhov dej los yog muab pov tseg rau hauv cov thoob khib nyiab li niaj zaus.
Xaus
GS441524 hmoovyog ib qho tshuaj tiv thaiv kab mob muaj zog uas muaj peev xwm tseem ceeb hauv kev kho cov kab mob kis, tshwj xeeb tshaj yog feline infectious peritonitis (FIP). Kev nkag siab txog nws cov khoom, yuav ua li cas kom tau nws, thiab nws cov ntawv thov tuaj yeem muab kev nkag siab zoo rau cov kws tshawb fawb, kws kho tsiaj, thiab cov tswv tsiaj. Yog xav paub ntxiv, thov hu rau peb ntawmSales@bloomtechz.com.
Cov ntaub ntawv
Pedersen, NC, et al. (2019). "Kev ua tau zoo thiab kev nyab xeeb ntawm Nucleoside Analog GS-441524 rau kev kho cov miv uas tshwm sim Feline Infectious Peritonitis." Phau ntawv Journal of Feline Medicine and Surgery, vol. 21, nr. 4, pp. 271-281 ib.
Murphy, BG, et al. (2018). "Lub Nucleoside Analog GS-441524 Muaj zog Inhibits Feline Infectious Peritonitis (FIP) Virus nyob rau hauv cov ntaub so ntswg kab lis kev cai thiab kev tshawb fawb miv kab mob." Veterinary Microbiology, Vol. 219 Ib., pp.
"GS-441524." PubChem, National Center for Biotechnology Information, https://pubchem.ncbi.nlm.nih.gov/compound/GS-441524.
Brown, AJ, et al. (2019). "Remdesivir: Broad-Spectrum Antiviral Activity thiab muaj peev xwm siv tau los kho ntau yam kab mob kis." Antiviral Research, vol. 169, 104547 ib.
"Nucleoside Analogs hauv Veterinary Medicine." Phau ntawv Journal of Veterinary Pharmacology thiab Therapeutics, vol. 4 3, nr. Peb Hlis 2, 2020, p. 115-129.