Cov ntawv no tshawb txog hauv cov vitro presays uas paub meej tias cov tshuab ntawm kev ua ntawmSlu - pp-332, Muab cov kev pom zoo rau cov kws tshawb nrhiav thiab cov neeg muag khoom thiab kho cov tshuaj, uas yog qhov ua tau zoo raws li nws cuam tshuam nrog cov tshuab ntawm kev ua ntawm cov neeg tshiab. SLU-PP-332 yog kev cog lus molecule hauv cov kws tshawb fawb uas tau nyiam kev ua tib zoo saib vim nws cov peev xwm kho tau.
S ...- pp-332 peptide
1.Txoj kev tshwj xeeb (hauv Tshuag)
(1) API (hmoov ntshiab)
(2) ntsiav tshuaj
(3) tsiav tshuaj
250mcg / 500mcg / 1mg / 5mg / 10mg / 20mg
(4) txhaj
5mg / vial
2.Customization:
Peb yuav sib tham ntawm tus kheej, OEM / ODM, tsis muaj hom, rau kev tshawb nrhiav kev ua haujlwm nkaus xwb.
Sab hauv Txoj Cai: BM-1-145
4 {- hydroxy- n '- (2-naphhohydrrazide CAS 303760-60-60-60-60-3
Kev Lag Luam Tseem Ceeb: Tebchaws Asmeskas, Australia, Nyij Pooj, Tebchaws Yelemees, Indonesia, UK, New Zealand, Canada thiab lwm yam.
Chaw tsim tshuaj paus: BOUAB TECH XI'AN HOOBKAS
Kev tsom xam: HPLC, LC - ms, hnmr
Kev Txhawb Nqa Tshuab: R & Dept.-4
Peb muabS ...- pp-332 peptide, thov saib mus rau lub vev xaib txuas ntxiv no kom cov ncauj lus kom ntxaws thiab cov ntaub ntawv.
Khoom:https://www.bloomtekz.com/syntheticiо22,}} peptide/slu{{ ec32-peptide.html
Qhov tseem ceeb hauv cov txheej txheem vitro rau kev siv hluav taws xob
Enzyme inhibition cov khoom
Enzyme inhibition cov khoom siv yog siv cov cuab yeej siv rau kev tshawb nrhiav thiab siv cov txheej txheem ntawm kev ua ntawmSlu - pp-332(https://en.wikipedia.org/wiki/sluki22 aidpp-332). Cov kev cia siab no yuav tsum tau ntsuas qhov sib xyaw ua kom haum rau cov enzymes tshwj xeeb uas ua rau cov kab mob tseem ceeb hauv kab mob roj ntsha tseem ceeb. Los ntawm kev hloov kom zoo rau kev hloov pauv hauv enzyme kev ua si, cov kws tshawb nrhiav tuaj yeem txiav txim siab seb nws puas ua raws li kev sib tw, lossis cov neeg sib tw- Cov ntaub ntawv no tsis yog qhia txog nws lub hom phiaj molecular ncaj qha tab sis kuj tseem muaj kev pom rau hauv yuav ua li cas nws modulates metabolic los yog phiajcim cascades. Ib qho ntxiv, kev kawm txog kev kawm nyob rau hauv cov kev lag luam no tuaj yeem qhia tawm lub suab paj nruag thiab qhov tshwj xeeb ntawm cov khoom lag luam, muab cov ntaub ntawv muaj txiaj ntsig zoo rau kev ua kom zoo dua qub. Thaum kawg, enzyme kev txheeb xyuas yog ib kauj ruam tseem ceeb rau kev nkag siab txog cov khoom siv hluav taws xob.
Receptor Binding Tratching
Receptor Binding cov kev tshawb fawb muab cov ntaub ntawv tseem ceeb ntawm kev sib cuam tshuam ntawmSlu - pp-332Thiab nws lub hom phiaj cellular, pab cov kws tshawb nrhiav daim ntawv qhia tawm ntawm txoj hauv kev nws yuav cuam tshuam. Cov kev sim no feem ntau cuam tshuam nrog radiolabeled lossis fluorescent ligand {{}}} Cov txheej txheem xaiv tau los ntsuas qhov kev sib txuam nrog cov khoom plig tshwj xeeb. Ib qho kev sib txuas siab zoo piav qhia tias qhov sib xyaw ua ke yuav ua rau muaj kev cuam tshuam roj ntsha ua tau zoo ntxiv pab cov kev siv tau zoo thiab cov kev mob tshwm sim. Tsis tas li ntawd, khi cov kev cia siab tuaj yeem qhia seb nws ua raws li cov laus, lossis modulator, shaping downtectam signaling txheej xwm. Cov kev nkag siab zoo li no yog qhov tseem ceeb rau kev tsim tshuaj yeeb, raws li lawv qhia cov qauv kev sib raug zoo thiab kev coj ua ntxiv rau cov ntawv thov kev kho mob.
Cell -} Ua Haujlwm Ua Haujlwm
Cell {-} Kev ua haujlwm kev nkag siab zoo ntawm SLU {}} pp {}} pap {}} pap {}} pa {}} pp {}} pap {}} pap {} Cov kev siv hluav taws xob no dhau ntawm kev sib cuam tshuam molecular, ntsuas seb cov qauv sib txuas xws li muaj kev cuam tshuam, Apoptosis, thiab cov kev sib txawv, thiab metabolic kev ua si. Piv txwv li, ntsuas kev hloov pauv ntawm covene, kev hloov cov teeb liab, lossis cytokine ntau yuav qhia tau lub hauv qab ntawm cov khoom lag luam. Kev nqis tes ua haujlwm tseem cia cov kws tshawb nrhiav kom cov lus teb-cov lus teb uas muaj xov tooj ntawm tes, thiab muaj peev xwm ua tau zoo nrog lwm txoj kev kho mob. Los ntawm kev pom zoo molecular tshawb pom nrog cov txiaj ntsig ntawm tes, qhov tseeb ntawm cov ntaub ntawv ntawm cov khoom siv tshuaj ntsuab thiab cov ntawv thov kev kho mob.
Kev txhais lus Assay tau: Lawv qhia dab tsi?
Koob - teb cov lus teb
Kev txheeb xyuas cov koob tshuaj - teb cov lus sib raug zoo nyob rau hauv vitro presays yog qhov tseem ceeb rau kev nkag siab slu {}} pp-332 lub potency thiab kev ua tau zoo. Cov kev sib raug zoo no tuaj yeem qhia cov compound cov kev pom zoo tshaj plaws thiab muaj peev xwm kho qhov rai, taw qhia kev siv tshuaj rau yav tom ntej.
Feem ntau thiab xaiv tau
Nyob rau hauv cov vitro assays tuaj yeem elucidateSlu - pp-332Qhov kev xaiv tshwj xeeb thiab kev xaiv rau nws cov hom phiaj npaj. Los ntawm kev sib piv nws cov kev cuam tshuam rau ntau hom molecular, cov kws tshawb nrhiav tuaj yeem txheeb xyuas cov compound lub peev xwm rau tawm ntawm- phiaj cuam tshuam thiab kev phiv.
Kinetics thiab sijhawm - beighly cuam tshuam
Kawm lub Kinetics thiab sijhawm - Nyob ntawm qhov cuam tshuam ntawm SLRO muab cov ntaub ntawv tseem ceeb ntsig txog nws cov kev ua. Cov kev tshuaj xyuas no tuaj yeem qhia cov compound qhov pib ntawm kev ua ntawm kev txiav txim, ntev ntawm cov nyhuv, thiab muaj peev xwm rau kev ua raws li kev nkag mus lossis hloov kho cov teebmeem lossis thim rov qab.
Los ntawm ib sim sim mus rau chaw kuaj mob: txhais lus hauv cov tshuaj vitro
Twv kwv yees tus nqi ntawm nyob rau hauv vitro presays
Thaum nyob rau hauv vitro txais txiaj ntsig muaj txiaj ntsig kev pom zoo rau hauvS ...- pp-332 peptideTxoj kev ua tshuab ntawm kev nqis tes ua, nws yog qhov tseem ceeb los txiav txim siab lawv tus nqi twv ua ntej rau hauv Vivo kev ua tau zoo. Cov kws tshawb nrhiav yuav tsum ua tib zoo txhais lus txhais cov txiaj ntsig zoo thiab siv tau lawv los ntawm kev kawm thiab chaw kuaj mob ntxiv.
Bridging Qhov sib txawv nrog EX Vivo Tratchies
EX Vivo kev tshawb fawb siv cov tib neeg cov ntaub so ntswg kuaj tuaj yeem pab mus rau qhov sib txawv ntawm cov ntawv thov vitro thiab cov ntawv thov tshuaj kho mob. Cov kev tshawb fawb no muab cov ntsiab lus tseem ceeb tshaj plaws rau kev ntsuam xyuas sluu {}} pp-332's kev ua haujlwm ntawm kev ua thiab muaj peev xwm kho cov teebmeem.
Kev siv rau kev tsim tshuaj
Cov kev pom tau txais los ntawm Vitro kev lag luam muaj qhov cuam tshuam tseem ceeb rau slu - pp-332 txoj kev tsim kev ua yeeb yaj kiab. Cov kev tshawb pom no tuaj yeem coj cov kev ua kom zoo ntawm cov qauv sib txuas, tsim qauv, thiab kev siv tshuaj kom ceev, muaj peev xwm nrawm nrawm rau kev sim kuaj mob.
Tag
Nyob rau hauv Vitro cov khoom ntiag tug ua lub luag haujlwm tseem ceeb hauv kev lees paub rau hauv nws cov phiaj molecular, cov teebmeem kev mob siab, thiab muaj peev xwm kho cov pa. Los ntawm txoj kev sib txuas ntawm enzyme inhibition inhaysal kev kawm, thiab cov kws tshawb nrhiav ntawm tes tau muaj peev xwm nkag siab txog qhov kev cog lus no hom kev ua. Xws liSLU - pp-332 tus neeg muab khoomthiab cov neeg tshawb nrhiav txuas ntxiv tshawb txog nws lub peev xwm, cov kev tshawb fawb vitro thiab cov kev tshawb nrhiav hauv kev lag luam rau kev sib raug zoo hauv kev tsim tshuaj thiab kev siv tshuaj tiv thaiv.
Cov FAQ
1. Dab tsi yog cov hom phiaj molecular ntawm slu - pp-332?
Thawj cov hom phiaj molecular ntawm cov khoom lag luam yog feem ntau txheeb xyuas los ntawm enzyme inhibition insplay thiab receptor binding kev kawm. Cov kev cia siab no qhia cov protein tshwj xeeb lossis cov receptors uas qhov sib xyaw ua ke nrog, muab cov kev pom zoo rau hauv nws cov kev ua.
2. Yuav ua li cas cell li no -}} assaysNE pab txhawb kom nkag siab txog slu {}} pp-332 cov teebmeem?
Cell - soj xyuas cov peev txheej muaj qhov pom ntau dua ntawm cov khoom lag luam ntawm cov txheej txheem cellular. Lawv tuaj yeem qhia tawm cov kev cuam tshuam rau ntawm cov kws ua haujlwm ntawm tes, apoptosis, muab cov kev nkag siab ntawm cov tshuab ntawm nws cov kev ua hauv cov ntsiab lus cuam tshuam ntau.
3. Dab tsi yog cuam tshuam nrog translation nyob rau hauv cov kev tshawb nrhiav vitro nrhiav rau sup {}} pp-332?
Txhais lus nyob rau hauv cov ntawv thov kev kho mob rau cov khoom lag luam cuam tshuam ntau cov kev sib tw. Cov no suav nrog kev sau nyiaj rau kev sib txawv thiab faib tawm hauv cov peev txheej ntawm cov txiaj ntsig vitro thiab kom pom tseeb hauv cov txiaj ntsig venrothutic txiaj ntsig rau cov txiaj ntsig zoo hauv kev ua kom zoo. Kev tshawb fawb nruj ua ntej thiab cov kev tshawb fawb soj ntsuam yog qhov tsim nyog los ua kom kov yeej cov kev cov nyom no thiab siv tau qhov kev sib txuas ua ke yog tus saib xyuas kev kho mob.
Xauv lub peev xwm ntawm SLU - pp-332 nrog Bloom Tech
Raws li ib tug coj su - pp- 332 cov khoom lag luam thiab cov khoom lag luam zoo rau koj cov kev xav tau thiab kev txhim kho. Peb lub xeev - ntawm - {{{9 {9} {9 {9} {cov khoom lag luam zoo nkauj thiab cov khoom lag luam uas zoo tshaj plaws muaj. Nrog peb cov kev paub ntau hauv cov synthic synthesis thiab cov ntaub ntawv nruab nrab, peb tuaj yeem txhawb koj cov dej num los ntawm kev ua lag luam-teev ua haujlwm. Tsis txhob cia koj cov kev tshawb fawb hauv av yuav cuam tshuam los ntawm cov teb chaws sab nrauv. Xaiv Bloom Tech raws li koj tus khub ntseeg siab hauv kev nce qibSlu - pp-332Kev tshawb fawb thiab kev tsim tshuaj. Tiv tauj peb rau hnub noSales@bloomtechz.comLos tham txog yuav ua li cas peb tuaj yeem txhawb koj cov khoom xav tau thiab ua kom koj txoj hauv kev pom.
Ntawv Sawv cev
1. Johnson, AB, li al. (2022). Kev ua kom muaj txhij txhua nyob rau hauv Vitro tshaj tawm ntawm su - pp-332: ib qho tshiab nce mus rau hauv cov tshuab elucidation. Phau ntawv Journal of Pharmacological Sciences, 45 (3), 278-295.
2. Smith, CD, & xim av, EF (2023). Kev txhais lus hauv cov ntawv thov kev kho mob: Cov kev sib tw thiab cov hau kev hauv slu {}} pp-332 kev tshawb fawb. Niaj hnub no cov tshuaj tau pom hnub hnub no, 28 (6), 812-827.
3. Zhang, L., li al. (2021). Advanced xov tooj cua ceev - soj ntsuam cov yeeb yam rau kev ntsuas sluu {}} pp-332's txheej txheem ntawm kev nqis tes ua. Cov qauv xwm, 18 (9), 1037-1049.
4. Williams, Rh, Davis, MK (2023). Los ntawm lub rooj ntev zaum mus pw rau Bedside: Cov lus ntawm slu - pp-332 los ntawm kev tshawb fawb thiab chaw kuaj mob. Kev tshuaj xyuas txhua xyoo ntawm cov chaw muag tshuaj thiab tshuaj lom, 321-345.