DL-Adrenaline Hydrochloride, tseem hu uaEpinephrine Hydrochloride, yog cov tshuaj neuroadrenaline nrog cov qauv molecular ntawm C9H13NO3·HCl thiab molecular hnyav ntawm 219.67g / mol. Nws yog dawb crystalline hmoov, yooj yim soluble hauv dej, nrog zoo nqus thiab bioavailability. Nws tau siv dav hauv kev lag luam tshuaj, kev tshawb fawb txog lub neej thiab kev ua kis las, thiab nws lub luag haujlwm tseem ceeb yog txhawm rau txhawb lub paj hlwb thiab adrenergic receptors, yog li hloov pauv lub cev lub cev thiab cov lus teb metabolic. Cov khoom no yog cov khoom siv sim, thiab nws yog txwv tsis pub siv rau lwm txoj hauv kev.
DL-Adrenaline Hydrochloride Cov hauv qab no yog cov kev siv tseem ceeb ntawm DL-Adrenaline Hydrochloride:
1. Kev kho mob hawb pob thiab bronchospasm: DL-Adrenaline Hydrochloride yog ib qho zoo bronchodilator thiab ua pa stimulant, uas yuav siv tau rau kev kho mob ntawm mob hawb pob, mob ntsws obstructive pulmonary kab mob thiab lwm yam kab mob ua pa.
2. Kev kho cov tshuaj tsis haum: Txij li thaum DL-Adrenaline Hydrochloride tuaj yeem txhawb kev ua kom lub siab zoo ntawm lub paj hlwb thiab kev tso tawm ntawm cov tshuaj soluble, nws tuaj yeem siv los txo lossis tiv thaiv kev tsis xis nyob thiab cov tsos mob tshwm sim los ntawm kev tsis haum tshuaj.
3. Kev kho mob plawv thaum muaj xwm txheej ceev: DL-Adrenaline Hydrochloride yog cov khoom siv vasoactive zoo, uas tuaj yeem siv rau kev kho mob plawv thaum muaj xwm txheej ceev xws li mob plawv nres thiab poob siab. Nws tuaj yeem ua rau lub plawv tso zis, systolic ntshav siab thiab lub plawv dhia, yog li txhim kho cov ntaub so ntswg oxygen; Nyob rau tib lub sijhawm, nws tuaj yeem nqaim cov hlab ntsha, txhim kho cov ntaub so ntswg perfusion siab thiab lub raum cov ntshav khiav.
4. Cov tshuaj loog hauv zos: DL-Adrenaline Hydrochloride tuaj yeem ntxiv dag zog rau cov nyhuv ntawm cov tshuaj loog hauv zos, ua rau cov hlab ntsha hauv thaj tsam tshuaj loog, yog li ncua lub sij hawm tshuaj loog, txo cov tshuaj loog thiab qhov tsis zoo.
5. Txhim kho kev ua kis las: DL-Adrenaline Hydrochloride tuaj yeem ua rau lub cev muaj zog, txhim kho kev ua siab ntev thiab cov tshuaj tiv thaiv ceev, yog li nws tau siv dav hauv kev ua kis las.
6. Kev tshawb fawb txog kev tshawb fawb: Raws li ib qho tseem ceeb tshuaj lom neeg thiab physiologically active tshuaj, DL-Adrenaline Hydrochloride yog dav siv nyob rau hauv kev sim kev tshawb fawb nyob rau hauv lub teb ntawm lub neej science, tshuaj thiab pharmacology, yog li txhawb txoj kev loj hlob thiab kev loj hlob ntawm lwm yam kev qhuab qhia.
Feem ntau, DL-Adrenaline Hydrochloride yog ib qho tseem ceeb heev neuroadrenaline tshuaj nrog ntau yam kev siv. Ntawm chav kawm, kev siv cov tshuaj no kuj yuav tsum tau them sai sai rau qhov tsim nyog npaum li cas, kev siv tshuaj thiab kev ceev faj kom tsis txhob muaj kev phiv thiab kev phiv.
Epinephrine Hydrochloride, tseem hu ua epinephrine hydrochloride, yog ib qho tshuaj tseem ceeb nrog ntau yam kev siv. Cov tshuaj tiv thaiv ntawm Epinephrine Hydrochloride yuav tau piav qhia hauv qab no, suav nrog nws cov khoom siv lub cev, cov khoom siv tshuaj, cov khoom siv hluav taws xob thiab cov khoom siv roj ntsha.
Chemical Properties:
1. Cov tshuaj tiv thaiv oxidation:
Epinephrine Hydrochloride tuaj yeem raug oxidation cov tshuaj tiv thaiv nrog oxygen, hydrogen peroxide thiab lwm yam oxidants los tsim cov tshuaj tiv thaiv oxidation, feem ntau yog homogeneous oxidation cov tshuaj tiv thaiv.
2. Txo cov tshuaj tiv thaiv:
Epinephrine Hydrochloride tuaj yeem raug txo qis cov tshuaj tiv thaiv nrog txo cov neeg ua haujlwm xws li sodium thiosulfate, hydrogen, thiab lwm yam los tsim cov tshuaj tiv thaiv txo qis.
3. Acid-base neutralization cov tshuaj tiv thaiv:
Epinephrine Hydrochloride yog ib hom hydrochloride, uas tuaj yeem ua rau cov tshuaj tiv thaiv tsis zoo nrog alkali los tsim dej thiab ntsev. Piv txwv li, thaum Epinephrine Hydrochloride reacts nrog sodium hydroxide, epinephrine, sodium chloride thiab dej yog generated.
Epinephrine Hydrochloride, feem ntau hu ua epinephrine lossis epinephrine guanidine, yog ib qho catecholamine compound uas yog cov khoom siv ua ntej ntawm epinephrine. Raws li ib qho tseem ceeb neurotransmitter thiab tshuaj, cov tshuaj muaj zog ntawm Epinephrine Hydrochloride tseem ceeb heev.
4. pKa tus nqi:
Tus nqi pKa ntawm Epinephrine Hydrochloride yog 8.96.
5. Kev ruaj ntseg:
Epinephrine Hydrochloride yog qhov ruaj khov ntawm chav tsev kub, tab sis nws yooj yim oxidized nyob rau hauv ib puag ncig oxidizing, degrading los tsim inactive compounds.
6. Scope ntawm daim ntawv thov:
Epinephrine Hydrochloride yog ib qho tshuaj tseem ceeb uas tuaj yeem ua rau cov hlab ntsha, dilate bronchi thiab txhim kho lub plawv contractility, thiab lwm yam. Nws tuaj yeem siv rau kev pabcuam thawj zaug thiab kho cov tshuaj tsis haum, mob hawb pob, mob plawv thiab lwm yam kab mob.
7. Optical zog:
Epinephrine Hydrochloride yog ib qho chiral compound nrog ob lub optically nquag isomers, L-epinephrine thiab D-epinephrine.
8. Toxicology:
Epinephrine Hydrochloride, raws li ib qho tshuaj, muaj qee yam toxicity. Cov koob tshuaj loj tuaj yeem ua rau muaj kev phiv xws li lub plawv dhia ceev thiab ntshav siab. Tsis tas li ntawd, vim hais tias nws tuaj yeem txhawb kev decomposition ntawm daim siab glycogen thiab tso cov suab thaj, kev siv tshuaj ntev ntev kuj tuaj yeem ua rau muaj teeb meem xws li ntshav qab zib thiab mob metabolic.
9. Radiation:
Epinephrine Hydrochloride tsis muaj hluav taws xob pom tseeb.
Hauv cov ntsiab lus, Epinephrine Hydrochloride yog ib qho tseem ceeb catecholamine compound nrog ntau yam kev siv tshuaj kho mob. Nws cov khoom siv tshuaj sib txawv raws li qhov sib txawv ntawm daim ntawv thov, thiab nkag siab txog nws cov khoom siv tshuaj pab kom nkag siab zoo dua nws cov tshuaj pharmacological thiab cov yam ntxwv ntawm daim ntawv thov.
Thermodynamic zog
1. Thaum tshav kub kub muaj peev xwm:
Lub peev xwm kub ntawm Epinephrine Hydrochloride ntawm chav tsev kub yog {{0}}.220 J / g / K, uas yog, nws qhov tshwj xeeb kub muaj peev xwm yog 0.220 J / (g·K).
2. Thermal conductivity:
Lub thermal conductivity ntawm Epinephrine Hydrochloride muaj feem xyuam rau cov concentration hauv nws cov tshuaj. Nyob rau hauv chav tsev kub, qhov thermal conductivity ntawm nws 2 feem pua cov kua yog 0.170 W/(m·K).
3. Cov tshuaj tiv thaiv thermochemical:
Cov tshuaj tiv thaiv thermochemical ntawm Epinephrine Hydrochloride muaj xws li combustion reactions, oxidation reactions, acid-base reactions, and reduction reactions. Hauv cov txheej txheem oxidation, Epinephrine Hydrochloride reacts nrog oxygen los tsim cov khoom oxidation cov tshuaj tiv thaiv; Hauv cov txheej txheem txo qis, Epinephrine Hydrochloride reacts nrog hydrogen los tsim cov khoom txo qis.
Biocompatibility:
Raws li cov neurotransmitter thiab xenobiotic, Epinephrine Hydrochloride muaj ntau yam cuam tshuam rau cov kab mob. Epinephrine Hydrochloride tuaj yeem cuam tshuam rau ntau yam kev ua haujlwm ntawm lub cev xws li lub paj hlwb, lub plawv, cov kab mob metabolic thiab daim siab hauv vivo.
1. Mechanism ntawm kev txiav txim:
Cov txheej txheem ntawm kev ua ntawm Epinephrine Hydrochloride yog tsuas yog los qhib lub paj hlwb los ntawm kev khi rau adrenergic receptors, yog li cuam tshuam rau cov hlab plawv, cov kab mob metabolic thiab lwm yam haujlwm. Nws tuaj yeem txhawb cov synthesis thiab tso tawm ntawm adenosine triphosphate (ATP) hauv lub cev, ua kom myocardial contractility thiab lub plawv dhia, ua kom lub plawv tso zis thiab ntshav siab; Nyob rau tib lub sijhawm, nws tuaj yeem ua rau lub cev tsis muaj roj thiab glycogen, thiab txhawb kev tso tawm thiab siv cov fatty acids thiab qabzib hauv lub cev.
2. Daim ntawv thov:
Epinephrine Hydrochloride muaj ntau yam kev siv hauv kev kho mob. Nws tuaj yeem siv los ua cov tshuaj kho mob plawv thiab cov tshuaj hemostatic rau cov xwm txheej kub ntxhov xws li ntshav poob, poob siab, thiab mob plawv nres hauv kev pab thawj zaug thiab phais. Tsis tas li ntawd, Epinephrine Hydrochloride kuj tseem siv tau rau hauv kev kho mob hawb pob, urticaria, anaphylactic shock thiab lwm yam kab mob.
Hauv kev xaus, Epinephrine Hydrochloride, ua ib qho tshuaj tseem ceeb, muaj cov tshuaj lom neeg nplua nuj thiab kev hloov pauv lom neeg. Nws muaj cov ntawv thov tseem ceeb hauv kev kho mob, muab kev txhawb zog rau kev pab thawj zaug, kev phais thiab kev kho mob.