Levamisole Hydrochloride, ib qho cawv molecule nrog cov mis C11H13ClN2S, yog ib qho tshuaj antihelminth dav siv hauv tsiaj thiab tib neeg. Cov compound feem ntau ua haujlwm los ntawm inhibiting lub paj hlwb kev ua haujlwm ntawm cov cab, yog li ua rau cov kab mob tuag. Tsis tas li ntawd, Levamisole Hydrochloride kuj muaj qee yam kev tiv thaiv kab mob tiv thaiv kab mob, uas tuaj yeem txhim kho kev tiv thaiv kab mob hauv lub cev thiab muaj txiaj ntsig zoo rau kev kho mob ntawm qee yam kab mob. Lub melting point yog 227 degree -233 degree, lub boiling point yog 407.7 degree, thiab lub ntiajteb txawj nqus tshwj xeeb yog 1.25. Nws cov khoom siv lub cev thiab cov khoom solubility raug cuam tshuam los ntawm qhov kub thiab txias thiab pH. Nws yog ib qho yooj yim kom nqus dej thiab decompose sai sai hauv qhov chaw ntub dej, thiab poob nws cov txiaj ntsig. Nws yuav tsum tau muab cia rau hauv qhov chaw txias thiab qhuav.
Levamisole Hydrochloride yog cov hmoov dawb crystalline feem ntau siv hauv kev kho tsiaj thiab kev kho mob. Nov yog tag nrho cov kev siv rau Levamisole Hydrochloride:
1. Kev siv Veterinary:
Levamisole Hydrochloride yog ib tug dav-spectrum anti-helminth tshuaj qhia rau kev kho mob ntawm ntau yam kab mob helminth nyob rau hauv cov tsiaj nyeg thiab nqaij qaib. Nws yog tsuas yog siv rau plab hnyuv helminth kab mob ntawm nees, plab hnyuv helminth kab mob ntawm nyuj thiab yaj, tsiaj me xws li dev thiab miv helminth kab mob, thiab nqaij qaib ntsws helminth kab mob. Tus nqi ntawm Levamisole Hydrochloride siv nyob rau hauv veterinary tshuaj yog txiav txim los ntawm qhov hnyav ntawm tus tsiaj thiab tus mob ntawm tus kab mob kab mob.
2. Tib neeg siv kev kho mob:
Levamisole Hydrochloride kuj tseem siv los kho cov kab mob helminth hauv tib neeg, uas feem ntau tshwm sim los ntawm cov kab mob cab. Qee cov kab mob helminth feem ntau muaj xws li kab mob plab hnyuv, mucosal nematodes, hookworms, thiab roundworms. Levamisole Hydrochloride tuaj yeem tiv thaiv kev loj hlob ntawm cov kab mob cab, tab sis kuj ntxiv dag zog rau lub cev tiv thaiv kab mob thiab ua kom lub cev tiv thaiv kab mob.
3. Immunomodulation lub hom phiaj:
Levamisole Hydrochloride kuj tseem siv los txhawb kev tiv thaiv kab mob thiab cob qhia lub cev kom tawm tsam qee yam kab mob thiab kab mob. Nws tau pom tias yuav ua rau muaj cov T cells thiab txhim kho lawv lub peev xwm paub txog thiab tshem tawm cov kab mob thiab cov kab mob. Levamisole Hydrochloride tuaj yeem txhawb nqa kev ua haujlwm ntawm cov qe ntshav dawb, yog li inhibiting cov qog nqaij hlav malignant.
4. Cov nyhuv detoxification:
Levamisole Hydrochloride tuaj yeem ua ke nrog qee cov co toxins kom ua rau muaj kev phom sij rau tib neeg lub cev. Tshwj xeeb, nws txo qis cov teebmeem ntawm cov tshuaj (xws li cocaine, fentanyl, thiab lwm yam), yog li txo qhov mob rau lub cev thiab lub hlwb. Txawm li cas los xij, qhov kev siv no tau ploj zuj zus vim Levamisole Hydrochloride nws tus kheej muaj qee yam kev mob tshwm sim.
5. Lwm yam kev siv:
Levamisole Hydrochloride muaj ntau lwm yam kev siv. Piv txwv li, nws tuaj yeem siv los kho cov kab mob autoimmune xws li angular cheilitis thiab kab mob rheumatoid, thiab nws tau raug pov thawj los txhim kho daim siab cirrhosis. Tsis tas li ntawd, Levamisole Hydrochloride feem ntau siv los kho cov qog nqaij hlav sib txawv.
Reactive zog ntawm Levamisole Hydrochloride:
(1) Cov kua qaub-puag khoom ntawm Levamisole Hydrochloride:
Levamisole Hydrochloride yog ib lub nplhaib heterocyclic nitrogen nrog cov yam ntxwv ntawm kev nqus spectrum. Nws yuav dhau los ua ib feem protonation cov tshuaj tiv thaiv nyob rau hauv acidic tej yam kev mob los tsim ntau soluble ntsev. Piv txwv li, hauv cov kua qaub me me, Levamisole Hydrochloride tuaj yeem hnov mob nrog bicarbonate los tsim cov ntsev carbonate soluble.
(2) Cov tshuaj tiv thaiv thermal decomposition ntawm Levamisole Hydrochloride:
Levamisole Hydrochloride decomposes ntawm qhov kub thiab txias los tsim ib tug sib tov ntawm diethylaminomethane sulfinate thiab flammable gases. Yog li ntawd, koj yuav tsum tau xyuam xim rau kev nyab xeeb thaum lub sij hawm cua sov txheej txheem.
(3) Txo cov tshuaj tiv thaiv ntawm Levamisole Hydrochloride:
Qee cov tshuaj txo qis tuaj yeem txo Levamisole Hydrochloride rau 1,2,3,4-tetrahydroheteroimidazole nrog kev tso tawm ib txhij ntawm hydrogen sulfide, piv txwv li, hlau anions nrog sulfoxide ligands (xws li Pd (OAc) 2 / NaBH4) thiab npib tsib xee (Ni /C), kuj xaiv tau raws li kev sib koom ua ke txo cov tshuaj tiv thaiv.
(4) Chlorination cov tshuaj tiv thaiv ntawm Levamisole Hydrochloride:
Levamisole Hydrochloride tuaj yeem chlorinated nyob rau hauv alkaline tej yam kev mob los ua N-ethyl-2-(2,3-dichloropropyl)-4-methyl-1,2,3,4-tetrazolidinedi Hydrochloride. Cov khoom no tuaj yeem siv los hloov Levamisole Hydrochloride rau qee qhov kev tshawb fawb lom neeg.
(5) Cov tshuaj tiv thaiv oxidation ntawm Levamisole Hydrochloride:
Levamisole Hydrochloride tuaj yeem oxidized los ntawm qee yam oxidizing cov neeg ua haujlwm xws li chlorine thiab hydrogen peroxide los tsim cov khoom oxidation. Raws li kev ua ntawm chlorine, Levamisole Hydrochloride tuaj yeem tsim sulfuric acid diethylaminomethane thiab sulfur chloride diethylaminomethane thiab lwm yam khoom. Nyob rau hauv qhov kev txiav txim ntawm hydrogen peroxide, Levamisole Hydrochloride tuaj yeem dhau los ua cov tshuaj tiv thaiv oxidation los tsim cov amino acids xws li cysteine thiab methylcysteine .
pH thiab Solubility:
Levamisole Hydrochloride yog ib qho organic compound nrog pH ruaj khov, thiab nws cov kua dej yog acidic tsis muaj zog. Thaum reacted nrog hydrochloric acid, Levamisole Hydrochloride tsim ib daim ntawv hydrophilic hydrochloride ntau dua.
Vim tias cov qauv molecular ntawm Levamisole Hydrochloride muaj qee qhov polarity, nws tuaj yeem muaj cov dej solubility zoo dua nrog dej thiab qee cov kuab tshuaj hydrophilic. Nyob rau hauv chav tsev kub, cov dej solubility ntawm Levamisole Hydrochloride yog 5.47 g / 100 mL, solubility yuav nce nyob rau hauv acidic tej yam kev mob, thiab solubility yuav txo nyob rau hauv alkaline tej yam kev mob.
Optical zog:
Cov qauv molecular ntawm Levamisole Hydrochloride muaj ib lub chaw chiral thiab muaj cov khoom siv kho qhov muag, thiab cov txiaj ntsig ntawm kev sib hloov kho qhov muag ntawm qhov sib cais ob enantiomers yog qhov sib txawv. Nyob rau hauv siab purity tej yam kev mob, Levamisole Hydrochloride tuaj yeem muab cais ua nws cov enantiomers.
Redox:
Levamisole Hydrochloride muaj qee yam redox zog, thiab nws tuaj yeem koom nrog hauv cov tshuaj oxidation thiab txo qis. Levamisole Hydrochloride yuav raug oxidized thaum raug huab cua los yog sib cuag nrog oxygen, thiab nws yuav hnov mob nrog qee cov oxidants (xws li peroxide, poov tshuaj permanganate, thiab lwm yam) kom tso tawm electrons thiab tsim cov khoom oxidation.
tshuaj tiv thaiv:
Levamisole Hydrochloride tuaj yeem cuam tshuam nrog qee pawg ua haujlwm, xws li esterification, hloov pauv thiab ntxiv cov tshuaj tiv thaiv. Hauv qee qhov xwm txheej, nws tuaj yeem oxidized rau cov khoom sib txuas hauv kev tswj hwm. Tib lub sijhawm, Levamisole Hydrochloride tuaj yeem tsim cov complexes nrog qee cov hlau ions.
Nyob rau hauv luv luv, Levamisole Hydrochloride yog ib tug organic compound nrog kuj zoo pH thiab solubility zoo, thiab nws kuj muaj optical kev ua si, redox thiab tej yam tshuaj reactivity. Cov khoom siv tshuaj no muab qee lub hauv paus rau kev siv Levamisole Hydrochloride hauv cov tshuaj, kev ua liaj ua teb thiab chemistry.