Lub ntsiab tivthaiv ntawm lidocaine hydrochloride txhaj yoglidocaine hydrochloride, siv raws li nws cov tshuaj loog hauv zos thiab antiarrhythmic tshuaj thiab feem ntau yog siv rau infiltration anesthesia, epidural tshuaj loog, tshuaj loog tshuaj loog thiab paj hlwb conduction thaiv. Lidocaine hydrochloride kuj tseem siv tau rau ventricular premature beats thiab ventricular tachycardia tom qab mob myocardial infarction. Nws kuj tseem tuaj yeem siv rau ventricular arrhythmias tshwm sim los ntawm digitalis lom, phais plawv thiab plawv catheterization. Tab sis feem ntau nws tsis zoo rau supraventricular arrhythmias. Cov lus qhia ntawm kev txhaj tshuaj lidocaine hydrochloride yog tshuaj loog hauv zos thiab antiarrhythmic. Nws yog feem ntau siv tshuaj loog hauv zos hauv kev kho mob. Nws yog tsuas yog siv rau infiltration, epidural, nto, thiab hlab ntsha conduction thaiv. Nws kuj tseem tuaj yeem siv rau ventricular premature beats thiab ventricular tachycardia tom qab mob myocardial infarction. Nws kuj tseem tuaj yeem siv rau ventricular arrhythmias tshwm sim los ntawm digitalis lom, phais plawv thiab plawv catheterization.
Txawm li cas los xij, vim lidocaine hydrochloride txhaj tshuaj feem ntau yog siv rau epidural block thiab sacral block hauv kev kho mob, txoj kev ntawm kev tswj hwm no muaj kev pheej hmoo siab rau tib neeg lub cev. Yog tias cov kua dej tsis yog isotonic, nws yuav ua rau muaj kev pheej hmoo ntawm kev siv tshuaj kho mob.
Cov mob hnyav tuaj yeem ua rau raug mob tsis tuaj yeem thiab txawm tias tus neeg mob tuag. Txawm li cas los xij, tam sim no version ntawm Suav Pharmacopoeia tus qauv rau kev txhaj tshuaj lidocaine hydrochloride tsis xav tau osmotic siab ntawm cov tshuaj, thiab qhov kev pheej hmoo tshwm sim los ntawm cov khoom isotonic tsis tuaj yeem zam. Nyob rau tib lub sijhawm, tus qauv pH ntawm lidocaine hydrochloride txhaj tshuaj nyob rau hauv tam sim no version ntawm Suav Pharmacopoeia yog pH 3.5 txog 5.5. Txawm li cas los xij, cov neeg mob uas muaj pH qis dua feem ntau muaj kev khaus khaus thaum siv tshuaj.Lidocaine hydrochlorideNyob rau hauv cov xwm txheej ntawm tus nqi pH qis Cov tshuaj loog ntawm cov tshuaj tua kab mob tsis pom meej, yog li cov neeg ua haujlwm kho mob feem ntau kho pH ntawm lidocaine hydrochloride txhaj rau 5.0 txog 7.0 ua ntej siv tshuaj kho mob.
Tseem muaj cov ntaub ntawv ua haujlwm qhia tias tom qab pH yog qhov tseem ceeb tshaj 6.0, kev ruaj ntseg ntawm cov tshuaj kuj tsis zoo, thiab cov khoom me me yog precipitated, yog li nws yuav tsum tau siv rau kev npaj kho mob - kev pheej hmoo ntawm tshuaj. Raws li kev soj ntsuam tshuaj nyab xeeb thiab kev ua tau zoo ntawm kev txhaj tshuaj lidocaine hydrochloride, Suav Pharmacopoeia 2015 tsab ntawv rau cov lus tau hloov kho cov qauv zoo ntawmlidocaine hydrochloride,Feem ntau pom nyob rau hauv osmolarity thiab pH ntsuas, Tus nqi pH raug kho rau pH 4.0-6.0, thiab tus qauv osmolarity yog 285-310 mOsm/Kg.