Paeonol yog dawb los yog daj ci iab acicular crystal, tsis muaj xim acicular siv lead ua (ethanol), melting point 49 degree -51 degree, tshwj xeeb tsw, me ntsis ntsim saj, yooj yim soluble nyob rau hauv ethanol thiab methanol, soluble nyob rau hauv ether, acetone, benzene, chloroform. thiab carbon disulfide, me ntsis soluble hauv dej, soluble hauv dej kub, insoluble hauv dej txias, thiab volatile nrog dej vapor. Nws yog ib qho zoo tivthaiv muab rho tawm los ntawm cov hauv paus hniav qhuav ntawm Ranunculaceae cog peony. Paeonol tuaj yeem distilled nrog dej vapor, thiab muaj zog nqus hauv cheeb tsam ultraviolet. Ntawm lub wavelength ntawm 274nm, e (1 feem pua 1cm) yog 862. Siv cov cuab yeej no, nws tuaj yeem txiav txim siab los ntawm ultraviolet spectrophotometer.
Txoj kev khaws cia ntawm paeonol: thauj raws li cov cai tswj kev siv tshuaj, tsis txhob muaj kev vibration muaj zog thaum thauj, thiab ua tib zoo saib xyuas thaum thauj; Kev ntub dej thiab kev puas tsuaj yuav tsum tiv thaiv. Khaws rau hauv qhov chaw txias, qhuav kom deb ntawm lub teeb.
Cov txheej txheem hluavtaws ntawm paeonol, ib qho zoo ntawm cov tshuaj suav tshuaj, tau kawm Txoj Kev: paeonol tau txais los ntawm resorcinol los ntawm acetylation nrog acetic acid thiab methylation nrog dimethyl sulfate Paeonol tau purified los ntawm chav distillation Cov txiaj ntsig: tag nrho cov txiaj ntsig ntawm paeonol yog 51.5 feem pua. Nws muaj pes tsawg leeg thiab cov qauv raug txiav txim los ntawm UV, IR, ^ 1hnmr, thiab lwm yam. purity yog raws li tus qauv ntawm Suav Pharmacopoeia (2005 tsab) los ntawm HPLC Cov Lus Qhia: paeonol nrog siab purity yog tau los ntawm resorcinol los ntawm chav distillation. Txoj kev no yog qhov yooj yim, pheej yig thiab yooj yim kom tau, thiab tsim nyog rau kev tsim khoom lag luam.
Paeonol muaj tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob thiab tshuaj tua kab mob. Nws muaj cov nyhuv analgesic pom tseeb ntawm qhov mob tshwm sim los ntawm lub cev lossis tshuaj lom neeg xws li tail pressing thiab acetic acid. Nws tuaj yeem cuam tshuam qhov kev mob tshwm sim los ntawm carrageenan, qe dawb, formaldehyde, histamine, 5-hydroxytryptamine, bradykinin, xylene thiab endotoxin. Nws muaj cov nyhuv antipyretic rau qhov nce ntawm lub cev kub los ntawm cov tshuaj tiv thaiv kab mob typhoid thiab tshuaj tiv thaiv triple. Nws tuaj yeem tiv thaiv hom II, III thiab IV kev ua xua.
Pharmacological teebmeem ntawm paeonol: nws muaj sedative, hypnotic, antibacterial, anti-inflammatory, anti-oxidation, ntshav siab thiab lwm yam teebmeem. Nyob rau hauv cov nqe lus ntawm chemistry txhua hnub, paeonol tuaj yeem cuam tshuam kev tsim cov O2 dawb radicals hauv cov hlwb, ua kom tawv nqaij dawb, txo thiab ploj cov xim tso rau hauv daim tawv nqaij, tshem tawm siltation thiab me ntsis, txo qis qhov mob, detumescence thiab mob, tiv thaiv kev tsis haum, tiv thaiv kab mob. thiab lwm yam teebmeem. Nws muaj kev kho mob zoo thiab kev saib xyuas kev noj qab haus huv ntawm cov pob qij txha, mob nqaij, khaus tawv nqaij, psoriasis, pob khaus khaus thiab eczema. Tsis tas li ntawd, nws muaj cov txiaj ntsig zoo ntawm cov tshuaj txhuam hniav, gargle, cov hmoov txhuam hniav thiab cov dej txhuam hniav.
(1) Ntxiv 0.25 feem pua rau cov qab zib zoo nkauj tuaj yeem txhawb cov ntshav ncig ntawm lub ntsej muag ntawm daim tawv nqaij, ua kom cov laus epidermal hlwb, tshem tawm wrinkles, tshem tawm pob, moisturize thiab zoo nkauj ntawm daim tawv nqaij.
(2) Ntxiv rau 0.3 feem pua tsuaj zawv plaub hau, nws tuaj yeem tshem tawm dandruff, txo qhov khaus, tswj cov plaub hau, moisturize, mos, ci, thiab txhawb cov plaub hau kev loj hlob.
(3) Ntxiv 0.25 feem pua ntawm lub ntsej muag lub ntsej muag kua tuaj yeem ua rau cov tawv nqaij dawb thiab mos, tiv thaiv kev laus, thiab muaj txiaj ntsig zoo rau pob txuv.
(4) Ntxiv 0.3 feem pua rau hauv cov kua da dej thiab xab npum tuaj yeem txhawb cov tawv nqaij metabolism, txhim kho cov xim ntawm daim tawv nqaij thiab tshem tawm pob txuv.
(5) Ntxiv 0.3 feem pua rau cov tshuaj txhuam hniav thiab gargle tuaj yeem txo qhov o thiab mob, tiv thaiv cov hniav caries, npog halitosis, thiab ntxuav lub qhov ncauj.
Paeonol muaj qee yam muaj txiaj ntsig zoo hauv kev txhim kho thiab kev siv cov khoom noj qab haus huv, tab sis tseem tsis muaj cov ntaub ntawv soj ntsuam txog kev nyab xeeb ntawm kev nyab xeeb thiab qhov tob. Txoj kev tshawb no tau tshawb pom qhov mob toxicity ntawm paeonol rau nematodes thiab cov teebmeem ntawm kev tawm dag zog, kev coj tus cwj pwm noj thiab kev muaj peev xwm ntawm kev yug me nyuam, thiaj li muab cov ntaub ntawv tshuaj ntsuam xyuas kev nyab xeeb rau kev txhim kho thiab kev siv paeonol ntsig txog cov khoom noj qab haus huv. Tus cwj pwm txav ntawm nematode yog qhov ntsuas qhia txog kev ua haujlwm ntawm nws lub cev. Nws yog ib qho yooj yim rau kev khiav lag luam, siab rhiab heev, yooj yim rau kev soj ntsuam, tus nqi qis thiab lub voj voog luv. Lub taub hau viav vias zaus thiab lub cev dabtsi yog khoov zaus ntawm nematode feem ntau yog siv los ua qhov ntsuas los ntsuas nws tus cwj pwm txav; Kev coj tus cwj pwm tuaj yeem cuam tshuam txog seb qhov kev pub mis ntawm nematodes puas cuam tshuam los ntawm cov tshuaj exogenous, thiab kev hloov pauv ntawm kev muaj peev xwm ua rau muaj peev xwm cuam tshuam txog cov tshuaj exogenous ntawm kev ua me nyuam thiab biochemical kev ua haujlwm ntawm nematodes. Qhov kev sim tau pom tias paeonol nrog cov concentrations ntawm 100 thiab 200mg / l tsis muaj tshuaj lom neeg mob rau nematodes tom qab 24 teev kho; Paeonol tuaj yeem txhim kho lub peev xwm txav ntawm nematode lub taub hau viav vias thiab lub cev khoov, thiab txhim kho kev ua haujlwm ntawm lub cev. 100mg / l paeonol muaj cov nyhuv zoo tshaj plaws. Paeonol tsis muaj kev cuam tshuam rau lub zog noj ntawm nematode, uas tuaj yeem txiav txim siab tias paeonol cuam tshuam rau kev ua haujlwm ntawm lub cev los ntawm kev txo qis nqos zaus ntawm nematode thiab tom qab ntawd txo qis zog txwv kev noj zaub mov. Paeonol tsis muaj kev cuam tshuam rau kev muaj peev xwm ua me nyuam, qhia tias nematode tseem nyob hauv lub xeev noj qab haus huv thaum nws ua. Paeonol tsis muaj tshuaj lom rau nematodes, thiab tuaj yeem txhim kho lub peev xwm ntawm nematodes. Nws muaj qee qhov peev xwm siv tau tus nqi hauv kev txhim kho thiab kev siv cov khoom siv kho mob.