Triphenylphosphine, ib qho organic compound nrog cov tshuaj formula c18h15p, yog dawb crystalline hmoov, insoluble nyob rau hauv dej, me ntsis soluble nyob rau hauv ethanol, soluble nyob rau hauv benzene, acetone, carbon tetrachloride, thiab yooj yim soluble nyob rau hauv ether. Nws yog tsuas yog siv nyob rau hauv cov organic synthesis. Nws yog raw khoom ntawm polymerization pib thiab tshuaj tua kab mob clindamycin. Nws kuj yog tus qauv qauv rau cov organic microanalysis thiab kev txiav txim siab ntawm phosphorus.
Nws yuav txhawb nqa tib neeg lub cev nyob rau hauv kev raug mob hnyav. Yog hais tias nws raug rau neurotoxicity ntev, nws yog ib yam khoom txaus ntshai thiab tsis tuaj yeem koom nrog cov oxidizing muaj zog. Lub reactivity ntawm aryl phosphines nrog oxygen yog qis dua li ntawm benzyl thiab alkyl phosphines. Txawm li cas los xij, oxidation ntawm triphenylphosphine los ntawm huab cua yog pom tseeb heev, tsim triphenylphosphine oxide. Triphenylphosphine tsis yooj yim rau ignite thiab tawg, tab sis thaum nws yog rhuab thiab decomposed, nws yuav tsim phosphine lom thiab pox pa luam yeeb. Kev ua haujlwm yuav tsum tau ua nyob rau hauv lub fume hood.
Synthetic triphenylphosphine: cua sov dispersed sodium xuab zeb tov ntawm 55 ~ 6 0 degree C, ntxiv 0.9 g ntawm dibromotriphenylphosphine nyob rau hauv kev tiv thaiv ntawm nitrogen, ces poob 3 ml ntawm 46.7 g ntawm chlorobenzene thiab 19. 0 g ntawm phosphorus trichloride sib tov, sawv ntsug rau 5 feeb, tos kom txog thaum cov xim dub tshwm hauv zos, tswj qhov kub ntawm 35 ± 5 ° C, thiab poob rau qhov sib tov, 1 Ua kom tiav hauv 5 teev. Nce qhov kub ntawm cov tshuaj tiv thaiv rau 55 ntxiv 5 "C, txuas ntxiv cov tshuaj tiv thaiv rau 30 feeb, txias thiab lim, ntxuav cov seem nrog 60ml toluene rau 3 zaug, muab cov tshuaj ntxuav thiab lim, mloog zoo, txias thiab precipitate dawb crystals, tag nrho ntawm 33.5g, qhov tawm los yog 92.4 feem pua (xws li PCB), thiab qhov purity yog ntau dua lossis sib npaug rau 99.0 feem pua (GC txoj kev).
Kev siv triphenylphosphine:
1. Nws yog siv los ua raw khoom rau organic synthesis, polymerization pib, tshuaj tua kab mob clindamycin, thiab tus qauv qauv rau organic microanalysis thiab kev txiav txim ntawm phosphorus.
2. Kev npaj palladium, iridium, rhodium, nickel thiab lwm yam complex catalysts, wfttig reagent, triphenylphosphine dihalide deoxygenation (N-pyridine oxide, nitroso benzene, hydroperoxide), desulfurization thiab debromination reagents. Ua ib-bromonitro compound tsim nitrile. Kev tshwm sim nrog fatty diazo tebchaw los ua ke ib _ Ketone aldehyde Monoketoacid. Beckmann rov kho dua. Dequaternization ntawm pyridinium ntsev. Nws yog siv nyob rau hauv ib co synthesis ua ke nrog bromine iodine, carbon tetrachloride (bromine), n-brominated butadiene imine, thiab lwm yam.
3. Triphenylphosphine yog ib qho kev txo qis heev. Feem ntau, cov tshuaj tiv thaiv yog tsav los ntawm kev tsim ntawm triphenylphosphine oxide (ib qho tshuaj tiv thaiv thermodynamically nyiam). Tsis tas li ntawd, triphenylphosphine yog dav siv raws li ligand rau hlau catalysts.
Deoxidizing tus neeg sawv cev. Photodelaying reagent. Azide reductant: nws tuaj yeem txo cov organic azide rau amine los ntawm kev sib xyaw nrog dej.
RN3plus PH3p plus H2O=RNH2plus PH3PO plus N2
alkynate diene cov tshuaj tiv thaiv catalyst: , - Alkynate yog rov kho dua rau hauv conjugated diene ester (sorbate) nyob rau hauv lub catalysis ntawm triphenylphosphine: phosphorus ylide siv nyob rau hauv lub synthesis ntawm Wittig cov tshuaj tiv thaiv:
H3P plus CH3Br → PH3P-CH3Br - (dry ether, Phli) → PH3P-CH2P
Deoxygenation triphenylphosphine yog siv dav hauv kev txo cov hydrogen peroxide lossis endoperoxide. Cov tshuaj tiv thaiv muaj feem xyuam rau cov substrate thiab tuaj yeem tsim cov cawv, carbonyl compounds lossis epoxides. Lub luag haujlwm tseem ceeb ntawm cov tshuaj tiv thaiv zoo li no yog tias triphenylphosphine tuaj yeem tsim muaj zog p=o daim ntawv cog lus nrog cov nyiaj tsis muaj zog OO (188 ~ 209 kj / mol). Piv txwv li, triphenylphosphine tuaj yeem siv los txo thiab decompose ntxhiab oxides thiab xaiv npaj ketones thiab aldehydes.
Cov tshuaj tiv thaiv nrog azides triphenylphosphine reacts nrog cov organic azides los tsim imino phosphine
Imino phosphine yog ib qho tseem ceeb ntawm nucleophile, uas yooj yim rau hnov mob nrog electrophiles. Piv txwv li, nws reacts nrog aldehydes thiab ketones tsim imines thiab triphenylphosphine oxides. Cov tshuaj tiv thaiv no zoo ib yam li Wittig cov tshuaj tiv thaiv, uas yog hu ua aza Wittig cov tshuaj tiv thaiv. Lub zog tsav ntawm cov tshuaj tiv thaiv no kuj yog vim qhov tsim ntawm triphenylphosphine oxide
Cov tshuaj tiv thaiv nrog cov organic sulfide triphenylphosphine tuaj yeem hloov pauv cov sulfur compounds rau olefins ntawm chav tsev kub
Dehalogenation cov tshuaj tiv thaiv - Brominated ketones teb nrog triphenylphosphine los tsim ketones
Cov tshuaj tiv thaiv nrog cov organic epoxides yog refluxed hauv dej thiab acetone hnyav, thiab triphenylphosphine tuaj yeem hloov epoxy compounds rau hauv cyclomines nrog kev koom tes ntawm sodium azide.
Kev npaj hloov pauv pyrrole aniline thiab furan Dione teb nrog triphenylphosphine los tsim 1-phenyl-2, 5-pyrrolidone
Raws li ib tug ligand ntawm hlau catalyst, nws tsim ib tug hlau catalyst nrog ntau yam kev hloov hlau raws li ib tug ligand. Piv txwv li, Pd (PPh3) 4 yog ib qho tseem ceeb catalyst, uas yog feem ntau siv nyob rau hauv catalytic coupling tshua. Nws yog ib txoj hauv kev tseem ceeb los tsim cov pa roj carbon monoxide. Nws cov yam ntxwv yog tias cov kab mob catalytic yog me me. Piv txwv li, nyob rau hauv kev sib koom ua ke ntawm PD (PPh3) 4 thiab Ag2O, phenylboric acid reacts ncaj qha nrog aromatic halogenated hydrocarbons los tsim biphenyl tebchaw, thiab cov tawm los ntawm cov tshuaj tiv thaiv no mus txog 90 feem pua.
Ntxiv rau phenylboric acid thiab halogenated tebchaw, magnesium reagents, zinc reagents, tin reagents, silicon tebchaw, thiab lwm yam yuav siv tau raws li substrates rau coupling tshua.
4. Nws yog dav siv nyob rau hauv kws tshuaj, petrochemical, txheej, roj hmab thiab lwm yam lag luam ua catalyst, accelerator, nplaim retardant, thiab analytical reagent.
5. Hauv cov tshuaj tua kab, trimethyl phosphite, ib qho nruab nrab ntawm organophosphorus, tuaj yeem ua ke los ntawm transesterification, thiab tom qab ntawd muaj cov tshuaj tua kab organophosphorus xws li dichlorvos, monocrotophos, phosphorylamine. Tsis tas li ntawd, nws tuaj yeem siv los ua tus stabilizer rau hluavtaws roj hmab thiab cob, ib qho antioxidant rau PVC, thiab cov khoom siv raw rau kev sib txuas ntawm alkyd resin thiab polyester resin.