Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab cov chaw muag khoom ntawm Fenbendazole Ivermectin hauv Suav teb. Txais tos rau kev lag luam wholesale loj zoo fenbendazole Ivermectin Kev Muag Khoom ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Cov khoom no yog ib qho tseem ceeb ntawmfenbendazole IvermectinThiab belongs rau qeb ntawm qhov ncauj semthetic broad -} spectrum antiparasitic tshuaj. Cov khoom no muaj cov nyhuv rau feem ntau nematodes (tab sis tsis yog txhua nematodes) hauv ntau lub neej lub neej; Ua tau rau cov microfilaments ntawm cov qauv tw FICARIAL HLAU, tab sis tsis muaj txiaj ntsig rau cov neeg laus cua nab; Nws tseem ua tau zoo rau kev quav tshuaj ntsuab uas tsuas yog nyob hauv txoj hnyuv. Cov khoom no muaj cov txiaj ntsig kev xaiv tsis tau los ntawm kev sib tw nrog cov kab mob cell mernels thiab cov leeg nqaij hlwb, thiab ua rau cov leeg tuag tes tuag taw, thiab tuag rau hauv cab tuag tes tuag taw lossis kev tuag.
Cov khoom no tseem tuaj yeem sib cuam tshuam nrog chloride ion raws raws ntawm lwm cov roj silandransmitter gamma aminobutyric acid (gaba). Kev xaiv ntawm cov khoom lag luam no yog vim qhov tsis muaj ntawm glutamate chloride ion raws cov tshuaj hiav txwv ntawm ionmalian rau cov tsiaj txhu rau cov tsiaj txhu rau cov tsiaj hiav txwv rau cov tsiaj hiav txwv rau cov tsiaj Cov khoom no tsis tuaj yeem nkag mus rau tib neeg cov ntshav -} biolrier. Onchociais thiab alpauv zoo li tus kab mob, nrog rau cov kab mob tshwm sim los ntawm hookworms, cov rauv taws, thiab cov cab.
Nyob rau tib lub sijhawm, peb lub tuam txhab tsis tsuas yog muab cov ntsiav tshuaj pab pawg neeg Ivermectin cov ntsiav tshuaj, tab sis kuj cream, muab tshuaj txhuam thiab hmoov. Yog tias xav tau, thov koj xav tiv tauj peb txhua lub sijhawm.
Peb Cov Khoom
| Khoom npe | Ivermectin Stromectol hmoov | Ntsiav tshuaj ivermectin stroomectol ntsiav tshuaj |
| Khoom Yam | Hmoov | Ntsiav tshuaj |
| Khoom Siv Purity | HPLC ntau dua los yog sib npaug rau 99.0% | Ntau dua los yog sib npaug rau 99% |
| Cov Khoom Qhia Khoom Khoom | 100g / 1kg / thiab lwm yam. | 360mg / ntsiav tshuaj |
| Khoom Pob | PE / AL NTAWV NYIAJ LUB HNAB / PAPTER BOX rau hmoov ntshiab |
100 ntsiav tshuaj / lub raj mis 80 lub hwj / thawv |
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Ivermectin Stromectol +. coa
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Daim Ntawv Pov Thawj Kev Ntsuam Xyuas |
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Compound npe |
Ivermectin | |
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Cas Tsis tau. |
70288-86-7 | |
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Teem nqi |
Qib kawm yog Veterinary |
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Qho ntau |
339.3kg |
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Ntim txheem ntim |
25Kg / nruas |
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| Tus tsim | Shaanxi Bloom Tech Co., Ltd. | |
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Lauj tsis tau. |
20250109001 |
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Mfg |
Jan 9th 2025 |
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Tus txeeb |
Jan 8th 2028 |
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Lub tsev |
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| Kuaj Tus Qauv | GB / T24768-2009 kev lag luam. Stnndard | |
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Yam |
Kev Lag Luam Kev Lag Luam |
Kev tsom xam tau |
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Kev tshwm sim |
Dawb lossis yuav luag dawb hmoov |
Hloov |
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Dej Cov Ntsiab Lus |
Tsawg dua los yog sib npaug rau 5.0% |
0.31% |
| Poob rau ziab |
Tsawg dua los yog sib npaug rau 1.0% |
0.15% |
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Cov hlau hnyav |
PB tsawg dua lossis sib npaug rau 0.5ppm |
N.D. |
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Tsawg tsawg dua li lossis sib npaug rau 0.5ppm |
N.D. | |
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Hg tsawg dua lossis sib npaug rau 0.5ppm |
N.D. | |
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CD tsawg dua lossis sib npaug rau 0.5ppm |
N.D. | |
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Purity (hplc) |
Ntau dua los yog sib npaug rau 99.0% |
99.4% |
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Ib Leeg Cav |
<0.8% |
0.48% |
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Residue ntawm ignition |
<0.20% |
0.064% |
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TAG NRHO LICBIAL COUNT |
Tsawg dua li lossis sib npaug rau 750cfu / g |
80 |
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E. coli |
Tsawg dua los yog sib npaug rau 2mpn / g |
N.D. |
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Tus ntses siav |
N.D. | N.D. |
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Ethanol (los ntawm gc) |
Tsawg dua los yog sib npaug rau 5000ppm |
400ppm |
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Chaw ntim khoom |
Khaws rau hauv ib qho chaw sib khi, qhov chaw tsaus thiab qhuav ntawm-20 degrees |
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Kev tsom xam ntawm cov tshuab thiab cov xwm txheej ntawm kev siv ua ke ntawm Fenbendazole thiab Ivermectin
Koom Tes Me Me Hlau: Qib Molecular Qib Sib Koom Tes
1. Lub tshuab ua haujlwm ntawm kev ua ntawm Fenbendazole
Fenbendazole yog qhov dav -} spectrum antiparasitic tshuaj siv rau benzimidagidazole chav kawm ntawm cov tebchaw. Nws cov tshuab ntawm kev nqis tes ua yog:
Tubulin inhibition:
Fenbendazole khi rau microlotubules hauv parasite hlwb, inhibiting lawv polymerization thiab cuam tshuam tus cab lub microlotuic system. Microlotuic System Plays lub luag haujlwm tseem ceeb hauv kev faib xov cell, cov khoom thauj, thiab tswj xyuas corportology. Nws cov kev cuam tshuam rau kev faib tawm ntawm tes thiab qhov txawv txav hluav taws xob hauv cab, thaum kawg kev loj hlob ntawm lawv txoj kev loj hlob thiab kev tu cig.
Kev cuam tshuam cov kua roj metabolic:
Fenbendazole tseem tuaj yeem txwv cov cab ntawm cov piam thaj, ua rau glycogen depetion thiab lub zog metabolism Thaiv, ntxiv nrawm paresite tuag.
Physiological qauv cuam tshuam kev cuam tshuam:
Rau qee lub parasites, xws li tooworms, fenbendazole tuaj yeem cuam tshuam rau lawv lub cev muaj sia tau txuas nrog phab ntsa plab hnyuv, ua rau lawv tshem tawm cov quav.
2. Lub tshuab ntsuas ntawm kev ua ntawm Ivermectin
Ivermectin yog macrolide tshuaj tua kab mob uas dav -} spectrum antiparasitic kev ua si. Nws cov tshuab ntawm kev nqis tes ua yog:
Neurotransmitter cuam tshuam:
Ivermecte kev tso tawm ntawm inibitory Neurotransransitter Gamma nyob rau hauv cab ( Qhov kev cuam tshuam rau kev cuam tshuam no tuaj yeem ua rau muaj kev ua yeeb yam ntawm tes tuag taw, thiab thaum kawg ua rau muaj kev cog lus, thiab thaum kawg ua rau cov cab no kom txav.
Lub zog metabolism inhibition:
Ivermectin tseem tuaj yeem cuam tshuam nrog lub zog metabolism hauv lub zog ntawm cov cab, los ntawm inhibiting lawv cov dej qab zib, tsis muaj peev xwm txo qis ntawm pawg tuag.
3. Kev sib koom tes ua ke rau kev siv sib koom tes
Thaum Fenbendazole thiab Ivermectin muaj siv ua ke, lawv txuam nrog sib txawv los ntawm kev sib txawv ntawm kev nqis tes ua, sib sau ua ntau {} Lub hom phiaj nres rau Parasites:
Kev nthuav dav ntawm cov khoom lag luam tawm:
Fenbendazole muaj cov nyhuv muaj zog rau ntawm nematodes, tsau thiab flumectin muaj qhov kev tua zoo rau nematodes thiab arthropodes (xws li mites thiab zuam). Kev sib xyaw ntawm ob qho tuaj yeem them yuav luag txhua hom cab hauv tsiaj txhu thiab nqaij qaib, suav nrog Nematodes, cov tshuaj ntsuab, thiab arthropods.
Kev siv tshuab ua tiav:
Fenbendazole feem ntau cuam tshuam nrog microlot barein thiab cov roj teeb cov roj teeb meem, thaum Ivermotin Mas cuam tshuam nrog Neurotransmitters thiab Caws Caws Raws. Kev rho tawm ntawm cov txheej txheem ntawm cov kev ua no tso cai rau kev tawm tsam ntawm kev cuam tshuam ntawm kev ua yeeb yam thiab txo qhov tau ntawm parasite tsis kam.
Kev Tshawb Fawb Hauv Kev Tshawb Xyuas: Tshawb Pom Kev Ua Tau Zoo thiab Kev Nyab Xeeb
1. Tsiaj txiav txim txiav txim siab
Kev noj cov pob txha caj dab uas tau sim ua ntej, tau muab faib rau pawg IvermectinS Monotherapy, Fenbendazle Mouseapy, ua ke kho, thiab tswj ntsug, feem. Cov txiaj ntsig tau pom tias pawg kws kho mob tau zoo dua li cov pab pawg neeg uas tsis zoo, ua rau muaj cov nyhuv tseem ceeb.
Kev kho mob ntawm npua hipsworm tus kab mob: kev kho kev kho ntawm Ivermectin thiab Fenbendazole tau siv los kho npua hwjsworm mob. Tom qab 3 hnub ntawm kev noj tshuaj, cov npua maj mam rov qab noj thiab muaj ntau yam tshuaj lom uas muaj kev kho mob zoo rau ntawm tus npua qhua zoo.
2. Kev tshawb nrhiav tib neeg cov ntawv thov
Anticancer muaj peev xwm: preclinical kev tshawb fawb tau qhia tias kev sib xyaw ntawm Fenbendazole thiab Ivermectis cuam tshuam rau cov kabmob cancer, inhibiting lawv cov khoom muaj peev xwm thiab metastasis. Muaj cov ntaub ntawv qhia tias kev kho kom haum muaj qee qhov kev kho mob qog nqaij hlav cancer thiab cov tshuaj ntsuam xyuas mob plab mog, tab sis ntau cov chaw kuaj mob me me yog xav tau los xyuas.
Kev Tshawb Fawb Txog Kev Tshawb Fawb: Hauv cov kev sim vitro qhia tau tias Fenbendazole thiab Ivermectinole thiab Ivermentin muaj peev xwm tiv thaiv cov protein ntau dua, los ntawm kev ua kom muaj peev xwm nkag mus.
Qhia tau thiab siv cov xwm txheej kev siv
1. Cov lus qhia tseem ceeb hauv thaj chaw ntawm cov kws kho tsiaj
Kev kho kom haum yog tsuas yog siv los tsav tsheb tam sim no cov kab mob, cov kab mob hnoos qeev, cov kab mob flueaus, nyuj, yaj, thiab nqaij qaib. Cov kev qhia tshwj xeeb yog raws li hauv qab no:
Nyuj: Nws muaj lub zog tua hluav taws kub ntawm cov ntshav caj dab Nematodes thiab upside hauv nyuj, thiab mob ntsws kom zoo tua sab nraud parasites xws li zuam thiab ntshauv.
TSIAJ: Nws muaj cov kev kho mob zoo rau cov kab mob parasitic xws li cov roundworms, hookworms, thiab pob ntseg mites hauv dev thiab miv.
Yaj: Nws tuaj yeem tsav tsheb tawm sab hauv parasites xws li moniz tapeworm thiab lober flueworm, nrog rau cov kab mob sab nraud xws li cov kiav txhab mite thiab khaus mite uas tuaj yeem tua cov yaj.
Npua: Nws tuaj yeem tsav tam sim ntawd ntau tus cab xws li cov kab mob npua ua ke, thiab kho cov plaub hau sab nraud xws li tus tsiaj pob liab vog thiab demodex mites.
Nqaij qaib: nws tuaj yeem tua cov hnyuv nematodes xws li cov roundworms thiab nematodes, nrog rau kev tswj hwm thiab tswj cov nqaij qaib sab nraud xws li cov nqaij qaib sab nraud uas muaj ntshauv.
2. Cov kev thov cuam tshuam tshwj xeeb
Kev Kho Mob Sib xyaw: Thaum cov tsiaj muaj kab mob ib txhij nrog ntau cov cab, sib xyaw ua ke tuaj yeem zam cov teeb meem tshuaj lom neeg thiab txhim kho kev kho cov kev kho mob thiab txhim kho kev kho mob.
Teb rau cov yeeb tshuaj - Cov tshuaj tiv thaiv: cab tsis kam mus rau ib qho tshuaj no tuaj yeem ua rau muaj kev sib raug zoo los ntawm kev sib raug zoo thaum siv ua ke.
Cov tsiaj tiv thaiv kab mob: sib xyaw ua ke tuaj yeem tswj kev tiv thaiv kab mob tiv thaiv kab mob thiab txo kev pheej hmoo ntawm cov kab mob thib ob.
Kev sib piv ntawm cov txheej txheem ntawm kev ua thiab synergistic meterism nruab nrab ntawm fenbendazole thiab Ivermectin
Kev koom tes thiab sib txawv hauv kev siv sib koom tes
| Mechanism ntawm Kev Ua: | Fenbendazole | Ivermectin | Synergy taw tes |
| Lub hom phiaj | MicroTovule System | Cov Metabolism Nurotransmitters | Ntau lub hom phiaj nres rau Parasites |
| Drew kev tawm tsam | Taenia thiab Flukes siv tau rau arthropods | Thaum cov roj av / flukes tsis muaj txiaj ntsig | Nthuav cov kev pab them nqi |
| Kev Taw Qhia Kev Taw Qhia Kev Ncaws Pob | Mas metabolized los ntawm lub siab | Feem ntau yog ua los ntawm ob lub raum | Txo kom lub siab thiab raum lub nra overlap |
Cov Mechanism ntawm Kev Ua ntawm Fenbendazole
MicroTuble Inhibition
Fenbendazole interrationation ntawm microlotubule hauv parasite lub cev, thiab thaum kawg ua rau lub cev tsis muaj peev xwm loj hlob thiab muaj peev xwm ua kom muaj peev xwm cog qoob loo thiab muaj peev xwm me me.
Kev tiv thaiv kab tiv thaiv kab mob thiab cov tshuaj tua kab mob antibacterial
Tswj cov lus teb tsis muaj zog, txhim kho kev muaj peev xwm tua cov cab, thiab muaj cov teebmeem hauv qee cov kab mob.
Cov tshuaj pleev cov tshuaj spectrum: nws yog qhov dav -}} wookworms, toochworms, thiab lwm yam orgendazole lub sijhawm ua haujlwm.
Kev cuam tshuam cov roj me me metabolism
Cov tshuaj noj tuaj yeem tiv thaiv cov parasite nce ntawm cov piam thaj, ua rau glycogen depletion, lub zog metabolism raug rhuav tshem, thiab nrawm parasite tuag.
Kev puas tsuaj rau lub cev tus qauv
Fenbendazole tuaj yeem cuam tshuam rau lub cev qauv ntawm kev ua kom zoo nkauj thiab lwm cov cab uas ua raws li phab ntsa plab hnyuv, tso cai rau lawv ua yeeb yaj kiab.
Lub tshuab ntawm kev ua ntawm Ivermectin
Neurotransmitter cuam tshuam
Nce kev tso tawm ntawm Gaba (GAMMA aminobutyric acid) hauv parasite lub cev sib kis, ua rau cab ua si tuag tes tuag taw, cov leeg kom txaus, thiab kev tuag.
Lub zog metabolism inhibition
Cuam tshuam nrog parasite glucose uptake, depleting zog cov peev txheej, thiab ua kom muaj kev tuag sai sai.
Anti Inflammatory thiab Kev Tiv Thaiv Tsis Tau
Inhibit Cov lus teb tsis pub dhau los, tswj cov kev sib npaug cytokine li cas, thiab txhim khu kev tiv thaiv host.
Cov tshuaj pleev cov tshuaj lom zem Spectrum: Zoo heev rau cov txiv kab ntxwv (xws li cov roundworms thiab hookworms) thiab arthropods (tab sis tsis muaj txiaj ntsig tawm tsam kev sib tw thiab flukes.
Cov tshuaj tiv thaiv tsis zoo
Fenbendazole Ivermectintau siv dav ua broad -} spectrum antiparasitic tshuaj nyob rau hauv cov tshuaj uas nyob rau hauv cov tsiaj siv thiab tib neeg tshuaj. Fenbendazole yog tsuas yog siv los kho cov plab zom mov ntawm cov tsiaj thiab cov dev uas muaj cov tsiaj txhu thiab cov kab mob Iventin thiab Scabies vim nws lub zog nematodes thiab arthropod cab cab. Txawm li cas los xij, nrog kev nthuav dav ntawm cov kev txwv ntawm cov tshuaj, ceeb toom ntawm cov kev cuam tshuam loj heev, immunosuppressed cov neeg mob tau muaj kev phom sij tau nyiam mloog.
Koob tshuaj noj
Kev siv dhau los siv yog qhov kev pheej hmoo tseem ceeb rau kev tawm tsam. Cov kev nyab xeeb ntawm Fenbendazole thiab IvermectAns thiab cov neeg coob heev (xws li ntau yam uas muaj kev sib tw), thiab ntau dhau ntawm cov tshuaj lom neeg) yuav ua rau muaj kuab lom. Piv txwv li, cov tshuaj pleev ntawm Ivermectin rau Collie dev yog 50 μ G / Kg, qhov kev pheej hmoo ntawm Neurotoxicity nce ntxiv los ntawm 5% rau 50%.
Cov Thawj Coj Qauv
Kev noj tshuaj nrawm nrawm nrawm nrawm thiab nce hauv zos; Kev noj tshuaj tom qab noj zaub mov txo qhov kev pheej hmoo ntawm kev phiv los ntawm cov zaub mov tsis haum thiab ncua plab. Piv txwv li, noj Fenbendazole 3 teev tom qab noj mov hauv cov dev ua rau 40% txo qis hauv kev ua kom tsis muaj peev xwm piv rau pab pawg ua haujlwm.
Cov tshuaj noj uas txhaj tshuaj tiv thaiv, tshwj xeeb ntawm kev txhaj tshuaj tiv thaiv, tej zaum yuav ua rau muaj kev tsis haum tshuaj rau cov ntshav, los ntawm kev nkag mus ncaj qha rau hauv cov ntshav "Thawj zaug dhau los". Piv txwv li, qhov tshwm sim ntawm kev fab tshuaj xua rau tib neeg Ivermectin Txhaj (3%) yog qhov siab dua li ntawm qhov ncauj tsim qauv (1%).
Ib tug neeg sib txawv
Kev yug menyuam nqa MDR1 Mene Coungations, xws li kev sib tsoo, yog rhiab rau cov neurotoxicity ntawm fenbendazole thiab Ivermectioninole Vim tias nce cov ntshav - barrier painerility, cov tshuaj yog tus luag rau hauv nruab nrab ntawm cov leeg hlwb.
Cov neeg muaj daim siab thiab lub raum tsis sib xws tau qeeb qeeb tshuaj metabolism thiab ua kom tiav, uas tuaj yeem ua rau muaj kev sib tw tau yooj yim. Piv txwv li, cov neeg mob uas muaj cov neeg mob nrog tus neeg mob uas siv Ivermectin uas siv cov ntshav ntau dua 2-3 lub sij hawm siab dua li cov tib neeg noj qab haus huv, thiab kev pheej hmoo ntawm neurotoxicity yog nce ntxiv.
Cov neeg mob immunosuppressive ntawm cov neeg mob (xws li cov kev hloov pauv nruab nrog cev) muaj kev pheej hmoo siab ntawm kev ua xua rau cov tshuaj. Vim tias lub cev tiv thaiv kab mob yog nyob rau hauv lub xeev ntawm high rhiab siab, nws yog ib qho yooj yim rau kev ua kom siab phem.
Cim npe nrov: Fenbendazole Ivermectinole, Cov neeg muab khoom, chaw tsim khoom, Hoobkas, lag luam wholesale, yuav, nqe, loj, loj, rau muag