Zoo tshaj Phenibut Hmoov CAS 1078-21-3

Cov khoom noj benzaldehyde tau ntxiv rau ethanol, nplawm nyob rau hauv cov zaub ncuav mog qab zib} Tom qab ntawd cov ephanol filtrate yog feeb kom muaj zog rau 1/4 ntawm thawj lub ntim {}} Cov kev daws teeb meem zoo yog txias tshuaj ntsuam xyuas, lim thiab dej cawv kom tau txais cov khoom ua ntej tau ua ke tom qab tau ua ke ob zaug {}}

Ntxiv thawj zaug hauv nruab nrab rau cov sodium hydroxide tov, do cov tshuaj tsw qab zib, muab cov lim dej, sib xyaw nrog cov khoom qab zib, muab cov lim dej ntxiv, ua kom tiav nrog cov khoom qab zib thib ob {}}

Kev daws teeb meem ntawm ob qho tib si ua tiav, precipitated . Cov khoom siv precipitated tau lim, ntxuav thiab qhuav kom tau txais cov khoom thib peb intermediate.

Yaj thib peb hauv nruab nrab hauv sodium hydrocide tov, thiab tom qab ntawd nws rov qab txias, thiab tom qab ntawd ntxiv cov tshuaj tiv thaiv hyprod, txias dua {1} filibuster, Kuv {. e. 4- amino {4 4}}}}}.

Cov Khoom Siv Raw: Phenol, Dosethyl sulfate, sodium hydroxide
Cov kev mob tshwm sim: Alkaline ib puag ncig, feem ntau yog siv sodium hydroxide tov raws li catalyst
C6h5oh + Ch3oso2och3 Naoh → C6h55och3 + naho4 +}}}}}
Nyob rau hauv cov kauj ruam no, phenol undergoent cov tshuaj tiv thaiv nrog sorium hydroxide los tsim p-methoxyphenol (animium

Cov Khoom Siv Raw: P-methoxyphenol, Aniline, Hydrochloric Acid
Cov mob tshwm sim: ib puag ncig acidic, feem ntau siv hydrochloric acid li catalyst thiab cov kuab tshuaj
C6h5Soc 3 + C6h5Nh}2 + hch5nhc6h4Ot {10} h2o
Nyob rau hauv acidic tej yam kev mob, P-methoxyphenol Undergoes Electrophes Uldophoes (devination) nrog Anilary los ua N-phenyl-p-mexyaniline thiab dej {{}

Nco ntsoov tias txoj kev ncaj qha los ntawm n-phenyl-p-methoxyaniline rau tsim ua tiav cov txheej txheem, thiab thaum kawg chloration)} Tab sis nyob rau hauv tiag tiag synthesis, kiag li kev sib txawv yuav siv .

Piv txwv li (tsis ncaj qha, tsuas yog ua piv txwv):
(1) aldehydes oxidized rau acids
RCHO Oxidant → rcooh
Ntawm lawv, r sawv cev rau cov pab pawg ua haujlwm tsis haum .
(2) acid chlorination rau acyl chloride
RCOOH + PRCL3 Pyridine → rcocl + pocl 3 + hcl
Los yog siv lwm cov tshuaj xhlorination xws li oxalyl chloride .
Txawm li cas los xij, thov nco ntsoov tias txoj kev saum toj no tsuas yog ua piv txwv, thiab nws tsis zoo li pib npaj benzoyl chloride {}}