Qhov zoo tshaj plaws phenibut hmoov, ib qho tshuaj hu ua 3-amino-4-phenyl butyric acid, yog cov hmoov dawb, uas yog hu ua - Cov tshuaj ntawm aminobutyric acid zoo ib yam . 3-amino-4-phenyl butyric acid hydrochloride yog cov feem ntau siv. Nws muaj kev cia siab ua lag luam zoo hauv Canada, United Kingdom, Tebchaws Meskas, New Zealand thiab lwm thaj chaw. Nws yog thawj zaug tsim rau cov neeg nyob hauv lub qub Soviet Union kom txo lawv txoj kev ntxhov siab yam tsis ua rau qaug zog. Nws yog feem ntau siv los npaj cov tshuaj tiv thaiv kev nyuaj siab. Nws yog ib qho tseem ceeb heev kws tshuaj intermediate, uas yuav siv tau nyob rau hauv kev soj ntsuam kev tshawb fawb thiab kev loj hlob txheej txheem thiab cov tshuaj-pharmaceutical ntau lawm txheej txheem.
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Melting point 252.5℃C (kwv yees ntxhib), Boiling point 311.75℃C (nrawm kwv yees), ceev 1.1248 (nrhiav kwv yees), Refractive index 1.5710 (kwv yees), Acidity coefficient (PKA) 4.10 ± 0.10 (predicted), Dangerous goods Classic to Xis. HMN: 5 mg/kg: CNS bexban 57,52,64
Phenibut COA
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Qhov zoo tshaj plaws phenibut hmoov, tseem hu ua 4-amino-3-phenylbutyrate hydrochloride, yog ib yam tshuaj uas muaj cov qauv zoo ib yam li gamma aminobutyric acid (GABA) hauv lub hlwb. Fenibat muaj qee yam kev siv hauv kev lag luam tshuaj, khoom noj qab haus huv, thiab kev tshawb fawb tshawb fawb, tab sis nws cov txiaj ntsig tshwj xeeb thiab kev nyab xeeb sib txawv hauv cov kev tshawb fawb sib txawv, thiab qee qhov kev thov tsis muaj pov thawj kev tshawb fawb los txhawb nws txoj kev siv.
1. Txo kev ntxhov siab thiab ntshai
Finibat ntseeg tau tias muaj kev txo qis ntawm kev ntxhov siab thiab kev ntshai, uas yuav cuam tshuam rau nws cov khoom raws li GABA analogue. GABA yog ib qho neurotransmitter uas ua lub luag haujlwm inhibitory hauv lub hlwb, pab tswj kev xav thiab txo qhov nro. Fenibat tuaj yeem ua tiav cov txiaj ntsig zoo sib xws los ntawm kev ua haujlwm ntawm GABA hauv lub hlwb. Txawm li cas los xij, qhov ua tau zoo ntawm qhov kev siv no tsis tau siv dav hauv kev kho mob.
2. Txhim kho kev pw tsaug zog
Fenibat yog siv los ntawm qee cov neeg ua ib qho ntxiv los txhim kho kev pw tsaug zog. Nws tau hais tias nws tuaj yeem pab tswj cov qauv kev pw tsaug zog thiab txawm tias nce lub sijhawm ntawm qhov muag nrawm nrawm (REM), uas yog qhov kev thaj yeeb nyab xeeb tshaj plaws thiab kev noj qab haus huv txhawb nqa theem ntawm kev pw tsaug zog. Txawm li cas los xij, kev tshawb fawb ntxiv yog xav tau kom paub meej txog cov txheej txheem tshwj xeeb thiab cuam tshuam ntawm nws txoj kev txhim kho ntawm kev pw tsaug zog.
3. Txo kev ntxhov siab thiab kev ntxhov siab
Zoo ib yam li kev txo cov kev ntxhov siab thiab kev ntshai, Fenibat kuj ntseeg tias yuav pab txo kev ntxhov siab thiab ntxhov siab. Qhov no tej zaum yuav yog vim nws tuaj yeem cuam tshuam qhov sib npaug ntawm cov neurotransmitters hauv lub hlwb, yog li txo qis excitation ntau dhau thiab tua cov neurons sai. Txawm li cas los xij, qhov kev siv no tseem tsis muaj pov thawj kev tshawb fawb txaus los txhawb nws.
4. Adjuvant therapy for post-Taumatic stress disorder (PTSD)
Txawm hais tias muaj cov ntawv ceeb toom qhia tias Fenibat tuaj yeem pab txo cov tsos mob PTSD, feem ntau ntawm cov ntawv ceeb toom no los ntawm cov kev tsis raug cai lossis cov xwm txheej ntawm tus kheej thiab tsis tau raug kuaj xyuas nruj hauv kev sim tshuaj. Yog li, nws cov txiaj ntsig zoo li PTSD cov tshuaj kho mob xav tau kev tshawb fawb ntxiv.
5. Txhim kho kev hais lus tsis zoo
Tam sim no tsis muaj pov thawj kev tshawb fawb pom tseeb txog qhov kev thov tias Fenibat txhim kho kev hais lus. Stuttering yog ib qho teeb meem hais lus nyuaj uas yuav tsum tau xav txog ntau yam, nrog rau kev puas siab puas ntsws thiab kev kho lus.
6. Antidepressant nyhuv
Qee qhov sib cav tias Fenibat tuaj yeem muaj qee yam tshuaj tiv thaiv kev nyuaj siab, tab sis qhov no kuj tsis muaj kev txhawb nqa los ntawm cov ntaub ntawv loj - cov ntaub ntawv soj ntsuam kuaj mob. Kev nyuaj siab yog ib qho kev puas siab puas ntsws loj, thiab nws txoj kev kho mob yuav tsum ua raws li kev qhia ntawm tus kws kho mob. Nws yuav tsum tsis txhob tso siab rau cov tshuaj uas tsis muaj pov thawj lossis tshuaj noj.
7. Tswj lub plawv dhia
Finibat tau hais nyob rau hauv qee qhov kev tshawb fawb rau nws lub luag haujlwm hauv kev tswj lub plawv dhia, tab sis cov ntaub ntawv ntawm qhov no muaj tsawg heev thiab tsis tau lees paub dav dav hauv zej zog kev kho mob tseem ceeb. Rau kev kho mob ntawm arrhythmia, ib tug yuav tsum ua raws li tus kws kho mob cov lus qhia thiab cov tshuaj kws kho mob.
8. Pab kom txhob haus cawv
Muaj cov ntawv ceeb toom qhia tias Fenibat tuaj yeem pab txo qis kev haus cawv thiab tsis xis nyob thaum haus cawv. Txawm li cas los xij, kev ua tau zoo thiab kev nyab xeeb ntawm kev siv no tseem xav tau kev tshawb fawb ntxiv thiab pov thawj. Kev txiav cawv yog txheej txheem nyuaj uas yuav tsum tau xav txog txhua yam xwm txheej thiab kev txhim kho cov phiaj xwm kho tus kheej.
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Peb yog cov chaw tsim khoom ntawm lubzoo tshaj Phenibut Powder.
Lus Cim: BLOOM TECH (Txij li xyoo 2008), ACHIEVE CHEM-TECH yog peb lub koom haum ntawm peb.
Txoj Kev 1:
Synthetic filibuster tuaj yeem muab faib ua cov kauj ruam hauv qab no:
Benzaldehyde thiab ethyl acetoacetate yog ntxiv rau ethanol, nplawm thiab hnov mob nyob rau hauv lub catalysis ntawm cov organic puag, thiab ces lim nrog lim ncuav mog qab zib. Tom qab ntawd, lim ncuav mog qab zib yog rinsed nrog ethanol, thiab lim ncuav mog qab zib yog qhuav kom tau cov khoom. Tom qab ntawd cov ethanol filtrate yog concentrated rau 1/4 ntawm thawj ntim. Cov tshuaj concentrated yog txias tsom xam, lim thiab cawv ntxuav kom tau cov khoom. Thawj qhov nruab nrab yog khoom tom qab ua ke ob zaug.
Ntxiv thawj qhov nruab nrab rau hauv cov tshuaj sodium hydroxide, do cov tshuaj tiv thaiv, lim nrog lim ncuav mog qab zib, ntxuav lub ncuav mog qab zib nrog dej tom qab pom, muab cov filtrate thiab txias nws, do thiab txias cov filtrate, ntxiv HCl los kho thaum stirring, lim, ntxuav nrog dej thiab qhuav tom qab stirring kom tau cov khoom thib ob intermediate.
Qhov thib ob nruab nrab yog yaj nyob rau hauv ntshiab acetic anhydride tov thiab refluxed. Tom qab ua tiav, acetic anhydride yog concentrated thiab tshem tawm thiab yaj hauv toluene. Tom qab dissolution, ammonia ntxiv. Tom qab cov tshuaj tiv thaiv tiav lawm, H2SO4 ntxiv dropwise nyob rau hauv ib da dej dej khov rau kev tswj, thiab ces cov khoom yog precipitated. Cov khoom precipitated yog lim, ntxuav thiab qhuav kom tau cov khoom thib peb nruab nrab.
Dissolve qhov nruab nrab thib peb hauv sodium hydroxide tov, maj mam ntxiv sodium hypochlorite tom qab txias, thiab tom qab ntawd ua cov dej khov da dej hauv lem. Tom qab cov tshuaj tiv thaiv tiav, txias nws dua. Tom qab txias, ntxiv hydrochloric acid los kho pH hauv dej khov da dej, do hauv chav sov rau decolourization, lim, thiab tom qab ntawd ntxiv hydrogen thiab oxygen hauv dej khov dej kom lim dua kom tau txais filibuster, piv txwv li . 4-amino-3-phenyl butyric acid.
Txoj Kev 2:
Cov kauj ruam ntxaws thiab tshuaj sib npaug rau kev sib txuas ntawmQhov zoo tshaj plaws phenibut hmoov
Cov khoom siv raw: phenol, dimethyl sulfate, sodium hydroxide
Cov kev mob tshwm sim: Alkaline ib puag ncig, feem ntau yog siv cov tshuaj sodium hydroxide ua catalyst
C6H5OH + CH3OSO2OCH3 NaOH → C6H5OCH3 + NaHSO4 + CH3OH
Hauv cov kauj ruam no, phenol tau txais cov tshuaj tiv thaiv methylation nrog dimethyl sulfate catalyzed los ntawm sodium hydroxide los tsim p-methoxyphenol (anisole) thiab los ntawm - khoom sodium bisulfate thiab methanol.
Raw khoom: p-methoxyphenol, aniline, hydrochloric acid
Cov kev mob tshwm sim: acidic ib puag ncig, feem ntau siv hydrochloric acid ua catalyst thiab hnyav
C6H5OCH3 + C6H5NH2 + HCl → C6H5NHC6H4OCH3 + H2O
Nyob rau hauv acidic tej yam kev mob, p-methoxyphenol dhau electrophilic hloov cov tshuaj tiv thaiv (amination) nrog aniline los tsim N-phenyl-p-methoxyaniline thiab dej.
Nco ntsoov tias txoj kev ncaj nraim los ntawm N-phenyl-p-methoxyaniline mus rau benzoyl chloride tsis raug. Txhawm rau tsim cov txheej txheem tiav, peb xav tias benzoyl chloride tau txais los ntawm qee qhov kev hloov pauv (xws li oxidation rau aldehyde, tom qab ntawd hloov mus rau acid, thiab thaum kawg chlorination). Tab sis nyob rau hauv qhov tseeb industrial synthesis, txoj kev sib txawv kiag li yuav siv tau.
Piv txwv li txoj kev (tsis ncaj qha, tsuas yog rau kev piav qhia):
(1) Aldehydes oxidized rau acids
RCHO Oxidant → RCOOH
Ntawm lawv, R sawv cev rau pawg ua haujlwm sib raug zoo.
(2) Acid chlorination rau acyl chloride
RCOOH + PCl3 Pyridine → RCOCl + POCl 3 + HCl
Los yog siv lwm cov tshuaj chlorination reagents xws li oxalyl chloride.
Txawm li cas los xij, thov nco ntsoov tias txoj hauv kev saum toj no tsuas yog ua piv txwv xwb, thiab nws tsis zoo li qhov kev sib txuas ntawm phenibut hauv kev tsim khoom tiag tiag yuav pib ncaj qha los ntawm N-phenyl-p-methoxyaniline los npaj benzoyl chloride.
Qhov cuam tshuam rau lub cev
Muaj peev xwm txaus ntshai thiab cuam tshuam tsis zoo rau lub cev
Neurological teebmeem
Kev siv sijhawm ntev ntawm Phenibut tuaj yeem ua rau lub cev thiab lub hlwb dependence. Thaum txiav tawm, tshem tawm cov tsos mob xws li kev ntxhov siab, insomnia, tshee, xeev siab, ntuav, thiab lwm yam. Cov tsos mob tshem tawm no tuaj yeem cuam tshuam rau lub neej zoo ntawm cov neeg mob thiab txawm tias ua rau muaj kev puas siab puas ntsws. Piv txwv li, qee cov neeg mob uas tau siv Phenibut ntev ntev tuaj yeem ntsib kev ntxhov siab thiab kev nyuaj siab hnyav tom qab txiav cov tshuaj, uas yuav tsum tau muaj kev kho mob kom txo tau. Txawm hais tias kev tshawb fawb txog cov neurotoxicity ntawm Phenibut tam sim no tsis txaus, ntev -lub sij hawm los yog siv ntau dhau yuav ua rau muaj kev puas tsuaj rau lub paj hlwb. Nws tuaj yeem cuam tshuam nrog kev sib npaug ntawm cov neurotransmitters, cuam tshuam rau kev ua haujlwm ntawm cov neurons, thiab ua rau kev paub tsis meej, nco tsis tau, thiab lwm yam teeb meem. Rau cov menyuam yaus thiab cov tub ntxhais hluas, lub paj hlwb tseem tsis tau tsim tag nrho, thiab siv Phenibut yuav muaj kev cuam tshuam tsis zoo rau lawv txoj kev loj hlob ntawm lub paj hlwb.
Cov teebmeem ntawm cov hlab plawv
Phenibut tuaj yeem cuam tshuam rau kev tswj ntshav siab, ua rau kom nce lossis txo cov ntshav siab. Kev hloov pauv hauv cov ntshav siab tuaj yeem ua rau muaj kev pheej hmoo ntawm cov kab mob plawv, xws li kab mob plawv, mob stroke, thiab lwm yam. Tshwj xeeb tshaj yog rau cov neeg uas twb muaj kab mob plawv, siv Phenibut tuaj yeem ua rau mob hnyav dua. Muaj cov lus ceeb toom tias tej zaum yuav muaj arrhythmia tom qab siv Phenibut. Arrhythmia tuaj yeem cuam tshuam rau kev ua haujlwm ntawm lub plawv, ua rau cov tsos mob xws li palpitations, hauv siab nruj, thiab kiv taub hau. Kev mob arrhythmia hnyav tuaj yeem ua rau lub neej- hem.
Psychological thiab puas siab puas ntsws cuam tshuam
Siv Phenibut tej zaum yuav ua rau lub siab hloov pauv xws li mus ob peb vas, chim siab, ntxhov siab vim, thiab lwm yam. Cov kev xav no yuav cuam tshuam rau tus neeg mob lub neej txhua hnub thiab kev sib raug zoo ntawm tus kheej. Piv txwv li, qee cov neeg mob tau ntsib kev ntxhov siab thiab kev tsis sib haum xeeb nrog tsev neeg thiab phooj ywg tom qab siv Phenibut. Lub sij hawm ntev lossis siv tsis raug ntawm Phenibut tuaj yeem ua rau muaj kev pheej hmoo ntawm kev mob hlwb xws li kev nyuaj siab, kev ntxhov siab, schizophrenia, thiab lwm yam. Cov mob hlwb no tuaj yeem muaj kev cuam tshuam loj rau lub cev thiab kev puas siab puas ntsws ntawm cov neeg mob, xav tau ntev -kev kho mob thiab kev rov zoo.
Lwm yam kev pheej hmoo
Phenibut tuaj yeem cuam tshuam nrog lwm yam tshuaj, cuam tshuam rau lawv cov txiaj ntsig thiab kev nyab xeeb. Piv txwv li, thaum siv nrog cov tshuaj tsaug zog, tshuaj loog, tshuaj tiv thaiv kab mob, thiab lwm yam tshuaj, nws tuaj yeem txhim kho cov teebmeem ntawm cov tshuaj no, ua rau muaj qhov tshwm sim tsis zoo. Yog li ntawd, thaum siv Phenibut, nws yog ib qho tsim nyog yuav tsum tau ceeb toom rau tus kws kho mob ntawm lwm cov tshuaj siv kom tsis txhob muaj kev cuam tshuam tshuaj. Txawm hais tias tam sim no muaj kev tshawb fawb tsis txaus txog kev puas tsuaj ntawm Phenibut rau lub siab thiab ob lub raum, ntev - siv sijhawm ntev lossis siv ntau dhau yuav ua rau muaj kev cuam tshuam rau cov kabmob no, ua rau muaj teeb meem xws li lub siab ua haujlwm tsis zoo thiab lub raum puas. Lub siab thiab ob lub raum yog ib qho tseem ceeb hauv metabolic thiab excretory kab mob nyob rau hauv tib neeg lub cev, thiab ib zaug puas lawm, lawv yuav cuam tshuam rau lub cev ua hauj lwm ntawm lub cev.
FAQ
1. Puas yog "qhov zoo tshaj" hmoov tsuas yog kev lag luam gimmick?
Yog lawm. Txhua daim ntawv lo uas piav txog cov khoom siv raw li "zoo tshaj" lossis "zoo tshaj" tsis muaj cov qauv kev cai lij choj. Qhov tseem ceeb tiag tiag nyob rau hauv thib peb -cov ntaub ntawv qhia txog kev coj dawb huv thiab cov hlau hnyav (CoA) rau txhua pawg, tsis yog kev lag luam. High purity tsis lav kev nyab xeeb.
2. Dab tsi yog qhov tsis sib xws hauv cov txheej txheem ntawm nws qhov kev txiav txim?
Ntawm cov koob tshuaj tsawg, nws tsuas yog ua rau GABA-B receptor los tsim kev tiv thaiv-txoj kev ntxhov siab; tab sis ntawm cov koob tshuaj ntau dua, nws tseem cuam tshuam rau GABA-A receptor thiab dopamine system, uas ua rau muaj kev sib txuam, koob tshuaj - nyob ntawm cov nyhuv spectrum xws li kev so mus rau sedation, mus rau euphoria (kev nkag siab zoo- ua) thiab muaj kev pheej hmoo siab heev ntawm kev vam khom.
3. Dab tsi yog qhov txaus ntshai uas raug lees paub tsawg kawg nkaus?
Mob nrawm siab ntev thiab tshwj xeeb ncua kev tshem tawm. Kev kam rau siab tuaj yeem tshwm sim tom qab tsuas yog ob peb hnub ntawm kev siv tas li, thiab qhov ntau npaum li cas yuav tsum tau nce ntxiv; thaum cov tsos mob tshem tawm (kev ntxhov siab hnyav, insomnia, palpitations) tom qab txiav tawm tuaj yeem nce siab tshaj 24-72 teev tom qab tso tseg cov tshuaj, thiab kav ntev, uas yooj yim misjudged thiab overlooked.
4. Puas muaj "kev nyab xeeb" txoj kev tau txais thiab siv nws?
Nws tsis muaj nyob. Nyob rau hauv ntau lub teb chaws, nws yog nruj me ntsis tswj raws li ib tug kws tshuaj los yog ib yam khoom uas tsis pom zoo. Ib qho kev nkag mus tsis raug cai yog txhaum cai thiab txaus ntshai. Txawm hais tias yog siv rau kev kho mob, vim nws qhov siab - qhov kev pheej hmoo ntawm kev vam khom, nws tsuas yog siv ceev faj thiab siv sijhawm luv luv los ntawm cov kws kho mob tshwj xeeb hauv ntau lub tebchaws. Kev pheej hmoo rau kev siv tus kheej yog qhov siab heev.
Cim npe nrov: Phenibut hmoov CAS 1078-21-3, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom