Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm dl-sulforaphane cas 4478-93-7 nyob rau hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo dl-sulforaphane cas 4478-93-7 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
DL -Sulforaphane, CAS 4478-93-7, cov mis mos molecular C6H11NoS2 yog cov kua daj lossis xim tsis muaj xim ntawm chav tsev kub, insoluble hauv dej, yooj yim soluble hauv cov kuab tshuaj organic xws li methanol, dichloromethane, acetonitrile, thiab lwm yam., thiab nquag decomposition nyob rau hauv high-temperature. Nws yog ib qho isothiocyanate ester tau los ntawm hydrolysis ntawm glucosinolates hauv cov nroj tsuag los ntawm myrosinase. Nws yog nplua nuj nyob rau hauv cruciferous nroj tsuag xws li broccoli, kale, thiab radish, thiab yog ib tug ntau yam antioxidant. Nws yog cov tshuaj tiv thaiv kab mob ntau tshaj plaws hauv cov zaub.
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Tshuaj Formula |
C6H11 NOS 2 |
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Exact Mass |
177 |
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Molecular Luj |
177 |
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m/z |
177 (100.0%), 178 (6.5%), 179 (4.5%), 179 (4.5%) |
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Elemental Analysis |
C, 40.65; H, 6.25; N, 7.90; O, 9.02; S, 36.17 |
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DL -Sulforaphane(SFN), tseem hu ua sulforaphane, yog ib qho isothiocyanate compound pom nyob rau hauv cov nroj tsuag cruciferous. Txij li thaum nws nrhiav tau nyob rau hauv lub xyoo pua 20th, nws cov qauv tshuaj tshwj xeeb thiab kev ua haujlwm lom neeg tau maj mam tshwm sim, dhau los ua qhov kev tshawb fawb hotspot nyob rau hauv thaj chaw ntawm cov khoom ntuj chemistry, khoom noj khoom haus, thiab tshuaj. Radish sulforaphane hloov los ntawm nws cov precursor glucosinolates nyob rau hauv qhov kev txiav txim ntawm myrosinase. Cov N=C=S pab pawg yog nquag rau polarization thiab tau txais ib qho txiaj ntsig zoo, ua kom yooj yim rau cov tshuaj nucleophiles xws li amino pawg, hydroxyl pawg, thiab carboxylic acids. Nws yog tus qauv tseem ceeb rau nws ntau yam kev ua ub no lom neeg.
Anti mob qog noj ntshav: ntau- lub hom phiaj inhibition ntawm qog tshwm sim thiab kev loj hlob
Kev tshawb fawb hauv thaj tsam ntawm kev tiv thaiv - mob qog noj ntshav yog qhov tob tshaj plaws hauv - qhov tob, thiab nws cov txheej txheem ntawm kev ua haujlwm muaj ntau yam xws li kev tswj hwm lub voj voog ntawm tes, apoptosis induction, angiogenesis inhibition, thiab txhim kho kev tiv thaiv kab mob.
1. Qhib Nrf2 txoj hauv kev los txhim kho cellular detoxification peev xwm
Nws yog lub zog ua kom muaj zog ntawm cov khoom siv hluav taws xob nuclear erythroid 2-txog yam 2 (Nrf2). Nrf2, raws li qhov kev hloov pauv, tuaj yeem tswj hwm qhov kev qhia ntawm ntau tshaj 500 cell tiv thaiv cov noob, suav nrog cov tshuaj tua kab mob antioxidant xws li glutathione S-transferase (GST) thiab superoxide dismutase (SOD), nrog rau detoxifying enzymes xws li glutathione synthase. Los ntawm kev ua kom Nrf2, sulforaphane tuaj yeem txhim kho cov hlwb tiv thaiv oxidative kev nyuaj siab thiab tshuaj carcinogens. Piv txwv li, hauv daim siab mob qog noj ntshav, kev kho mob ua ntej tuaj yeem txo cov DNA puas tsuaj los ntawm aflatoxin B1 thiab txo cov qog nqaij hlav.
2. Inducing cancer cell apoptosis thiab inhibiting proliferation
Los ntawm kev tswj cov kev qhia ntawm lub voj voog ntawm tes muaj feem xyuam rau cov proteins xws li Cyclin D1 thiab CDK4, cov qog nqaij hlav cancer raug ntes nyob rau theem G1, thaum ua kom cov proteins caspase tsev neeg los ua rau mitochondrial txoj kev apoptosis. Hauv cov qog nqaij hlav cancer ntawm lub mis, nws tuaj yeem tswj cov kev qhia ntawm cov tshuaj tiv thaiv apoptotic protein Bcl-2, nce qib ntawm pro apoptotic protein Bax, thiab thaum kawg ua rau kev tuag ntawm tes. Tsis tas li ntawd, nws tuaj yeem cuam tshuam cov phosphorylation ntawm epidermal growth factor receptor (EGFR), thaiv cov kev taw qhia hauv qab, thiab yog li inhibit cov qog nqaij hlav cancer.
3. inhibit angiogenesis thiab metastasis
Cov qog loj hlob vam khom rau neovascularization muab khoom noj khoom haus, uas tuaj yeem cuam tshuam cov kab mob angiogenesis los ntawm kev txo qis ntawm vascular endothelial kev loj hlob yam (VEGF).
Hauv cov qauv nas ntawm cov kab mob qog noj ntshav, kev tswj hwm qhov ncauj ntawm sulforaphane tuaj yeem txo cov qog ntim txog li 60% thiab txo qis qhov tshwm sim ntawm lub ntsws metastasis. Cov txheej txheem cuam tshuam nrog inhibiting kev ua haujlwm ntawm matrix metalloproteinases (MMPs), txo cov cellular matrix degradation, thiab yog li cuam tshuam cov kab mob qog noj ntshav thiab metastasis.
4. Txhim khu kev tiv thaiv kev tiv thaiv kev ua haujlwm
Nws tuaj yeem tswj hwm kev ua haujlwm ntawm lub cev tiv thaiv kab mob thiab txhim kho lub cev tiv thaiv kab mob rau cov qog. Piv txwv li, nws tuaj yeem txhawb kev loj hlob ntawm cov hlwb dendritic thiab txhim kho lawv cov peev xwm nthuav tawm antigen; Tib lub sijhawm qhib cov neeg tua neeg (NK) hlwb thiab cytotoxic T lymphocytes (CTL) txhawm rau txhim kho cov nyhuv tua ntawm cov qog nqaij hlav cancer. Hauv cov neeg mob qog noj ntshav, kev sib xyaw ua ke ntawm sulforaphane tshuaj thiab kws khomob tuaj yeem ua rau muaj kev vam meej tsis muaj sia nyob.
Antioxidant thiab tiv thaiv -inflammatory: tiv thaiv cov hlwb los ntawm kev puas tsuaj
Kev ntxhov siab oxidative thiab mob ntev yog cov hauv paus pathological ntawm ntau yam kab mob, thiab lawv tiv thaiv cov teebmeem los ntawm kev siv dual.
1. Ncaj qha tshem tawm cov dawb radicals
N=C=S pawg hauv sulforaphane molecules muaj qhov polarity muaj zog thiab tuaj yeem ua rau cov pa oxygen reactive (ROS) xws li superoxide anions (O ₂⁻) thiab hydroxyl radicals (· OH) los tsim cov adducts ruaj khov, yog li ncaj qha neutralizing dawb radicals. Kev sim hauv vitro tau pom tias sulforaphane muaj qhov kev tshem tawm ntau dua 90% tawm tsam DPPH dawb radicals, thiab nws cov peev xwm antioxidant yog 10 npaug ntawm cov vitamin C.
2. Ua kom cov kab mob antioxidant enzyme
Los ntawm kev ua kom txoj hauv kev Nrf2, kev qhia ntawm cov enzymes antioxidant xws li glutathione peroxidase (GPx) thiab heme oxygenase-1 (HO-1) tuaj yeem raug ntxias, txhim kho lub peev xwm endogenous antioxidant ntawm cov hlwb.
Hauv cov qauv nas ntawm Alzheimer's disease, pretreatment nrog sulforaphane tuaj yeem txo cov ntsiab lus ntawm lipid peroxidation khoom malondialdehyde (MDA) hauv cov ntaub so ntswg, thaum nce SOD kev ua haujlwm thiab txhim kho kev txawj ntse.
3. inhibit inflammatory signaling pathways
DL -Sulforaphanetuaj yeem txo qis kev ua haujlwm ntawm cov khoom siv hluav taws xob nuclear kappa B (NF - κ B) thiab txo qhov kev tso tawm ntawm pro- cov kab mob inflammatory xws li qog necrosis factor alpha (TNF - ) thiab interleukin -6 (IL-6). Hauv cov qauv nas ntawm tus mob rheumatoid mob caj dab, kev txhaj tshuaj hauv zos ntawm sulforaphane tuaj yeem txo qhov o thiab txo cov ntshav C-reactive protein (CRP) qib, nrog rau cov nyhuv piv rau methotrexate.
Cov txheej txheem metabolic: txhim kho kev rog thiab ntshav qab zib
Nrog rau thoob ntiaj teb kev nthuav dav ntawm cov kab mob metabolic, lawv lub luag haujlwm hauv kev tswj hwm qhov hnyav, tswj ntshav qabzib, thiab tswj hwm lipid metabolism tau nyiam heev.
1. Txwv tsis pub muaj roj ntau thiab txhawb kev siv hluav taws xob
Nws tuaj yeem cuam tshuam qhov sib txawv ntawm adipocytes thiab lipid synthesis los ntawm kev ua kom AMP activated protein kinase (AMPK) txoj hauv kev. Nyob rau hauv siab - cov khoom noj rog uas ua rau cov nas rog rog, cov tshuaj sulforaphane tuaj yeem txo qhov hnyav ntawm epididymal rog txog li 30%, thaum nce cov nqaij tawv nqaij tawv nqaij tawv (BAT) thermogenesis thiab kev siv hluav taws xob.
2. Txhim kho cov tshuaj insulin
Nws tuaj yeem txhim kho qhov kev qhia ntawm insulin receptor base-1 (IRS-1) thiab txhim kho cov teeb liab insulin.
Hauv hom 2 mob ntshav qab zib nas, qhov ncauj sulforaphane tuaj yeem txo cov ntshav qabzib sai ntawm 25% thiab txhim kho cov ntshav qabzib siab. Cov txheej txheem tseem cuam tshuam nrog inhibiting cov haujlwm ntawm lub siab tseem ceeb gluconeogenesis enzyme phosphoenolpyruvate carboxykinase (PEPCK).
3. Tswj qhov sib npaug ntawm plab microbiota
Nws tuaj yeem txhawb kev loj hlob ntawm cov kab mob muaj txiaj ntsig xws li Bifidobacterium thiab Lactobacillus, thiab inhibit qhov kev loj hlob ntawm cov kab mob pathogenic xws li Escherichia coli thiab Clostridium. Hauv cov tib neeg rog rog, ntxiv nrog sulforaphane rau 12 lub lis piam sib law liag tuaj yeem ua rau cov ntsiab lus ntawm luv saw fatty acids (SCFAs) hauv cov quav, txo cov plab hnyuv permeability, thiab txhim kho metabolic endotoxemia.
Neuroprotection: ncua kev loj hlob ntawm cov kab mob neurodegenerative
Nws tuaj yeem nkag mus rau hauv cov ntshav- hlwb thaiv thiab tawm dag zog tiv thaiv, tiv thaiv- mob, thiab tiv thaiv apoptotic cuam tshuam hauv cov ntaub so ntswg hauv hlwb, muab cov tswv yim tshiab rau kev kho cov kab mob neurodegenerative xws li Alzheimer's disease thiab Parkinson's disease.
1. Txo qhov tso tawm ntawm - amyloid protein
Nyob rau hauv tus qauv nas ntawm Alzheimer's tus kab mob, nws tuaj yeem inhibit qhov kev ua ntawm - secretase 1 (BACE1) thiab txo qhov tsim ntawm - amyloid protein (A ); Ib txhij txhawb cov phagocytosis ntawm A plaques los ntawm microglia thiab txo cov A load hauv lub hlwb.
2. Tiv thaiv dopaminergic neurons
Lub ntsiab pathological feature ntawm Parkinson tus kab mob yog kev tuag ntawm dopaminergic neurons nyob rau hauv lub substantia nigra ntawm lub midbrain, thaum sulforaphane tuaj yeem qhib txoj hauv kev Nrf2, upregulate glutathione (GSH) qib, thiab txo oxidative kev nyuaj siab puas tsuaj los ntawm 6-hydroxydopamine (6-OHDA). Nyob rau hauv tus qauv ntawm tus kab mob Parkinson, pretreatment nrog sulforaphane tuaj yeem ua rau kom muaj sia nyob ntawm neuronal los ntawm 40%.
3. Txhim kho kev txawj ntse
Muaj peev xwm txhawb nqa hippocampal neurogenesis thiab txhim kho synaptic plasticity. Hauv cov nas laus, kev ntxiv ntxiv ntawm sulforaphane rau 8 lub lis piam tuaj yeem txhim kho qhov muaj peev xwm nco tau, thiab nws cov txiaj ntsig zoo piv rau kev paub txog kev txawj ntse ua tiav.
Clinical Application thiab Product Development
Raws li cov pov thawj scientific saum toj no, nws tau siv dav hauv kev lag luam khoom noj qab haus huv, khoom noj khoom haus, thiab tshuaj.
1. Cov khoom noj qab haus huv thiab khoom noj khoom haus
Nyob rau hauv lub ntiaj teb no kev ua lag luam, sulforaphane tshuaj muaj nyob rau hauv daim ntawv ntawm mos capsules, nyuaj capsules, thiab ntsiav tshuaj, feem ntau yog ua los ntawm broccoli noob extract. Piv txwv li, Nutramax Laboratories 'Avmacol cov khoom ua kom muaj txiaj ntsig ntawm kev hloov pauv ntawm sulforaphane hauv cov hnyuv los ntawm kev ua kom muaj zog myrosinase; Jarrow Formulas 'BroccoMax siv kev txhawb nqa -tso thev naus laus zis los txuas ntxiv lub sijhawm ua haujlwm.
2. Kev loj hlob ntawm cov zaub mov ua haujlwm
Nws tuaj yeem ntxiv rau cov dej haus, yogurt, lub zog tuav thiab lwm yam khoom noj kom tau raws li cov neeg siv khoom xav tau kev noj qab haus huv yuag. Piv txwv li, ib hom ntawm broccoli paj bud thiab yub cov kua txiv hmab txiv ntoo muaj 15mg ntawm sulforaphane ib lub raj mis, uas yog sib npaug rau haus 300g ntawm broccoli tshiab.
3. Kev nce qib hauv kev tshawb fawb thiab kev tsim kho tshuaj
Tam sim no, ntau qhov kev sim tshuaj tsom rau sulforaphane tab tom ua. Piv txwv li, ib theem II sim ua los ntawm Johns Hopkins University tau pom tias cov tshuaj sulforaphane tuaj yeem txhim kho lub ntsws ua haujlwm tau zoo hauv cov neeg mob uas muaj kab mob ntsws ntev (COPD); Hauv cov neeg mob uas tsis yog - haus dej cawv fatty siab kab mob, sulforaphane tuaj yeem txo cov rog hauv siab txog li 20%.
Los ntawm kev tiv thaiv- mob qog noj ntshav mus rau neuroprotection, sulforaphane tau dhau los ua "lub hnub qub molecule" hauv thaj chaw ntawm cov khoom siv tshuaj lom neeg vim nws cov phiaj xwm ntau yam thiab ntau txoj hauv kev lom neeg. Nrog rau kev txhim kho cov cuab yeej siv hluav taws xob hluavtaws, qhov loj - teev ntau lawm thiab cov txheej txheem xa tawm ntawm sulforaphane tau txhim kho tas li, thiab nws qhov kev cia siab rau kev kho mob yuav ua kom dav dua.
Synthesis txoj kev ntawmDL -sulforaphane:
Thioside thiab myrosinase ruaj khov nyob rau hauv cov ntaub so ntswg ntawm cov nroj tsuag thiab vacuoles, feem. Tsuas yog thaum cov ntaub so ntswg puas tsuaj tuaj yeem radish sulfur yuav hydrolyzed. Vim tias cov txheej txheem hydrolysis yuav cuam tshuam los ntawm pH, qhov kub thiab txias, noo noo thiab lwm yam, cov txiaj ntsig ntawm sulforaphane feem ntau txo. Txawm hais tias lub ntuj enzymatic hydrolysis tau yooj yim cuam tshuam los ntawm ib puag ncig sab nraud, qhov chaw enzymatic hydrolysis uas tsim nyog rau kev sib txuas ntawm sulforaphane tuaj yeem tsim raws li cov yam ntxwv ntawm sulforaphane. Piv txwv li, qhov tsim nyog enzymatic hydrolysis pH yog 5 ~ 7, uas yog tsim nyog rau cov synthesis ntawm sulforaphane.
Cov hom thiab genotypes ntawm cov nroj tsuag muaj kev cuam tshuam loj heev rau sulforaphane synthesis hauv lawv lub cev, thiab cov ntsiab lus sulforaphane nyob rau hauv ntau hom zaub yog txawv heev. Kev tshawb fawb qhia tau hais tias cov ntsiab lus ntawm sulforaphane nyob rau hauv Brassica zaub yog siab tshaj nyob rau hauv Brassica, thiab cov ntsiab lus ntawm sulforaphane nyob rau hauv broccoli yog siab heev, mus txog 480 μ g · g-1 DW. Cov ntsiab lus ntawm glucosinolates nyob rau hauv ntau hom ntawm tib cov zaub kuj txawv heev.
P é rez-Balibrea et al. qhia tias cov nroj tsuag genotype thiab nws qhov chaw loj hlob yog qhov tseem ceeb cuam tshuam rau radish sulfur cov ntsiab lus, thiab genotype plays lub luag haujlwm tseem ceeb.
Lub Tsev Kawm Ntawv Qib Siab Kev Ua Liaj Ua Teb thiab Toj roob hauv pes Architecture ntawm Hunan Agricultural University tau ua tiav kev yug me nyuam ntawm siab -radish sulfur broccoli ntau yam tau ntau xyoo, thiab xaiv tshiab siab -radish sulfur broccoli ntau yam Xianglu 2 thiab Xianglu 3, nteg lub hauv paus rau kev yug me nyuam ntawm high{4} radish variegated. Lub gene network ntawm sulforaphane biosynthesis txoj kev yog qhov nyuaj heev, muaj ntau yam tseem ceeb, xws li epithelial sulfur tshwj xeeb protein (ESP), dub mustard enzyme regulatory gene (MY), selenium methyltransferase gene (SMT), thiab lwm yam.
Kev tshawb fawb qhia tau hais tias ESP nyob rau hauv broccoli yog ib tug protein nyob rau hauv lub dub mustard enzyme system. Nws tshaj - qhia tau zoo rau kev tsim cov nitriles thiab inhibits cov synthesis ntawm sulforaphane; MY ncaj qha tswj cov enzymes dub mustard, thiab SMT tuaj yeem tswj cov ntsiab lus sulforaphane nyob rau hauv kev ntxhov siab selenium. Cov txiaj ntsig ntawm kev xeem dhau ntawm MY thiab SMT qhia tau tias ob qho tib si MY thiab SMT tuaj yeem ua rau cov ntsiab lus sulforaphane nce ntxiv. Cov noob no muaj feem xyuam rau cov enzyme tseem ceeb ntawm radish sulfur synthesis - dub mustard enzyme, uas tswj cov kev qhia thiab kev ua haujlwm ntawm dub mustard enzyme. Yog li ntawd, txhim kho cov kev ua ntawm dub mustard enzyme nyob rau hauv radish sulfur synthesis tuaj yeem txhim kho cov ntsiab lus ntawm radish sulfur, thaum SMT noob tuaj yeem txo qis ntawm radish sulfur cov ntsiab lus los ntawm kev sib tw metabolism ntawm leej faj thiab selenium.
(1) Lub teeb zoo:
Lub teeb zoo sib txawv muaj qee yam cuam tshuam rau cov ntsiab lus ntawm leej faj hauv cov nroj tsuag radish. Cov ntsiab lus ntawm glucosinolates nyob rau hauv broccoli seedlings nyob rau hauv lub ntuj lub teeb yog ho ntau dua li nyob rau hauv qhov tsaus ntuj nti. Lub teeb tseem tuaj yeem ua rau cov ntsiab lus ntawm radish sulfur hauv radish callus, thiab cov nyhuv ntawm lub teeb liab thiab xiav yog qhov tseem ceeb. Lub teeb xiav luv yog pab tau kom cov ntsiab lus ntawm sulforaphane hauv broccoli ua ntej sau. Yog li ntawd, lub teeb tuaj yeem nce cov ntsiab lus ntawm radish sulfur hauv cov nroj tsuag. Lub teeb liab thiab xiav tuaj yeem tsim nyog ntxiv kom muaj cov ntsiab lus ntawm radish sulfur hauv kev cog qoob loo sab hauv, thiab thaj chaw uas muaj lub teeb txaus tuaj yeem xaiv rau kev cog qoob loo.
(2) Kub:
Kev sib xyaw ntawm sulforaphane xav tau qhov kub thiab txias kom ua rau cov protein ua haujlwm hauv txoj kev sib txuas mus txog qhov zoo tshaj plaws hauv lub xeev. Cov txiaj ntsig tau pom tias cov ntsiab lus ntawm sulforaphane hauv radish nce ntxiv thiab cov ntsiab lus ntawm sulforaphane hauv radish txo qis tom qab cov noob qoob loo tau kho nrog qhov kub siab (60 degree); Tab sis thaum kub txog 70 degree, cov ntsiab lus ntawm sulforaphane thiab sulforaphane poob. Txawm li cas los xij, muaj qee qhov kev tshawb fawb txog qhov no, thiab tsis muaj pov thawj txaus tias qhov kub thiab txias tuaj yeem tswj hwm sulforaphane synthesis.
DL-Sulforaphane sawv cev rau kev hloov pauv hauv cov khoom siv kho mob, kev sib txuas ntawm cov khoom noj khoom haus thiab chaw muag tshuaj. Nws cov txheej txheem ntau yam -xws li los ntawm Nrf2 ua kom muaj kev hloov pauv hloov pauv hloov pauv hloov pauv- txhawb nqa nws cov txiaj ntsig thoob plaws ntau yam kab mob. Thaum noj zaub mov noj muab cov txiaj ntsig zoo, SFN ntxiv muaj peev xwm kho tau. Kev tshawb fawb tsis tu ncua thiab kev tsim kho tshiab tau cog lus tias yuav nthuav dav nws cov ntawv kho mob, ua kom SFN lub luag haujlwm ua lub hauv paus ntawm cov tshuaj sib xyaw. Raws li peb nthuav tawm nws qhov nyuaj, SFN sawv ua pov thawj rau lub zog ntawm bioactive compounds muab los ntawm xwm.
DL-Sulforaphane yog ib hom kev sib xyaw ntawm ntuj sulforaphane (R-form). Nws qhov kev tshawb pom thiab kev tshawb fawb tau nyob ze rau ntawm kev ua haujlwm tiv thaiv kab mob ntawm cov nroj tsuag cruciferous.
Los ntawm xyoo 1970 mus txog rau xyoo 1980, kev tshawb fawb txog kev kis mob tau pom tias kev noj cov zaub cruciferous tau cuam tshuam nrog kev txo qis ntawm kev mob qog noj ntshav, tsav lub zej zog kev tshawb fawb los tshawb nrhiav cov tshuaj nquag. Thaum xyoo 1980s lig, Prochaska pab neeg tau tsim qhov kev tshuaj ntsuam xyuas rau theem II detoxification enzyme-inducing kev ua si thiab pom tias broccoli extract tau nthuav tawm cov haujlwm muaj zog tshaj plaws. Hauv xyoo 1992, pab pawg coj los ntawm Paul Talalay ntawm Johns Hopkins University cais thiab txheeb xyuas R-sulforaphane los ntawm broccoli, lees paub tias nws yog lub zog theem II enzyme inducer, uas tau pib tshawb fawb boom hauv sulforaphane.
Raws li kev tshawb fawb tau nce zuj zus, tshuaj synthesis tau dav siv los ua kom tau raws li qhov xav tau ntawm kev npaj loj thiab kev tshawb fawb txog kev ua haujlwm. Kev sib xyaw ntawm R- thiab S-enantiomers tsim thaum lub sijhawm sib txuas, uas yog DL-sulforaphane, maj mam dhau los ua ib qho kev tshawb fawb tseem ceeb. Cov kev tshawb fawb tom qab tau lees paub tias DL-sulforaphane tseem muaj cov haujlwm lom neeg xws li ua kom Nrf2 txoj hauv kev, tiv thaiv oxidation, thiab tiv thaiv kab mob. Txawm hais tias nws txoj haujlwm monomeric qis dua me ntsis ntawm lub ntuj R-daim ntawv, nws tau siv dav hauv cov khoom noj khoom haus thiab kev tsim tshuaj vim nws yooj yim synthesis thiab cov nqi tswj tau.
FAQ
Leej twg yuav tsum tsis txhob noj sulforaphane?
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Sulforaphane, uas muaj nyob rau hauv cov zaub cruciferous xws li broccoli, feem ntau muaj kev nyab xeeb nyob rau hauv cov zaub mov, tab sis cov concentrated tshuaj yuav tsum tau zam los yog siv nrog ceev faj los ntawm cov poj niam cev xeeb tub / pub niam mis, cov neeg uas muaj iodine deficiency hnyav, cov thyroid kab mob (hypothyroidism), los yog cov neeg noj tej yam tshuaj.
sulforaphane ua dab tsi rau koj lub cev?
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Sulforaphane yog ib qho muaj zog antioxidant thiab tiv thaiv - cov kab mob inflammatory muaj nyob rau hauv cov zaub cruciferous (broccoli, sprouts) uas neutralizes co toxins, tiv thaiv DNA, thiab txo kev pheej hmoo ntawm mob qog noj ntshav. Nws txhawb nqa kev noj qab haus huv hauv lub plawv, txhim kho kev nkag siab ntawm insulin, muab kev tiv thaiv neuroprotection, thiab pab lub siab detoxification los ntawm kev ua kom txoj hauv kev Nrf2.
Puas yog sulforaphane nyuaj rau daim siab?
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Tsis ntev los no, ntau cov kev tshawb fawb tau tshaj tawm tias SFN tuaj yeem ua rau mob siab rau lub siab thiab tiv thaiv kev loj hlob ntawm daim siab rog, txhim kho cov tshuaj insulin, txo qis oxidative puas thiab mob siab, ua rau apoptosis, thiab inhibit qhov kev loj hlob ntawm hepatoma hlwb los ntawm ntau lub teeb liab ...
Cov zaub mov twg siab tshaj hauv sulforaphane?
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Broccoli sprouts yog qhov siab tshaj plaws ntawm sulforaphane, muab txog li 100 npaug ntawm cov precursor glucoraphanin dua li broccoli paub tab. Lwm qhov chaw saum toj kawg nkaus suav nrog cov zaub nyoos los yog maj mam steamed cruciferous zaub xws li broccoli, Brussels sprouts, kale, cabbage, cauliflower, thiab watercress. Siv lawv nyoos los yog chopped yog qhov zoo tshaj plaws rau cov txiaj ntsig siab tshaj plaws.
Cim npe nrov: dl-sulforaphane cas 4478-93-7, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom