Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab cov khoom lag luam ntawm phenacetin hmoov li 62-44-2 hauv Suav teb. Txais tos rau kev lag luam wholesale loj zoo phenacetin hmoov cas 62-44-2 Kev muag khoom ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Zaj tshaj tawm
Cov tshuaj no txwv tsis pub muag, thiab peb lub vev xaib tsuas saib tau cov ntaub ntawv yooj yim. Peb tsis muag tshuaj ntawm no!
Lub Kaum Hlis 28, 2025
Phenacetin hmoov,Zoo li cov hmoov dawb huv, cov hmoov dawb huv lossis dawb, cov lus qhia tsis meej pem, muaju cem. Nws cov qauv crystalline muab nws lub teeb ci tshwj xeeb thiab kev ntxhib los mos. Nws yog tsis zoo soluble hauv dej, nrog solubility ntawm kwv yees li 0.076 g ib 100 ml dej. Txawm li cas los xij, nws yog me ntsis soluble hauv dej npau. Ib qho ntxiv, nws yog micro - soluble hauv diethyl ether tab sis soluble hauv ethanol thiab chloroform. Phenacetin tsis sib xws nrog oxidizing oxidizing cov neeg sawv cev thiab muaj zog acids. Nws nrog cov tshuaj no yuav ua rau cov tshuaj lom neeg thiab muaj peev xwm kev nyab xeeb kev nyab xeeb. Nws tau cais raws li Carcinogen los ntawm lub koom haum thoob ntiaj teb rau kev tshawb fawb txog mob qog noj ntshav (iarc). Ntev {- lub sij hawm los yog siab- Kev siv tshuaj phenacetin yuav ua rau muaj kev pheej hmoo mob cancer.
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Tshuaj Cov Qauv |
C10H13no2 |
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Muaj pes tsawg leej |
179 |
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Molecular hnyav |
179 |
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m/z |
179 (100.0%), 180 (10.8%) |
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Kev Ntsuam Xyuas |
C, 67.02; H, 7.31; N, 7.82; O, 17.85 |
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Cov hau hluav taws xob
Phenol acetic acid txoj kev yog ib qho ntawm cov txheej txheem synthesis ntawmPhenacetin HmoovCov. Nws pib nrog kev npaj phenacetin los ntawm para acetyl angsic acid acid (paa). Cov hauv qab no yog cov kauj ruam tshwj xeeb:
- Kauj Ruam 1: n {- acetylation actures: acetoacetic acid tuaj yeem npaj los ntawm kev ntxiv cov tshuaj tiv thaiv cov kua qaub rau cov acidet acid rau n- acetylation.
Paa + ch3Co las2H + C2H5Naj2Ch3Tus conhc2H5+ Ch3Co las2H + H2O
- Kauj Ruam 2: Cov tshuaj eserification: Tom ntej no, nyob rau hauv muaj cov sulfuric acid, acetylated Ethetificate cov tshuaj tiv thaiv hauv Carbonhloride los tsim cov phenacetin.
Ch3Tus conhc2H5 + C6H5Oh → c6H5OCONESC2H5 + H2O
C6H5OCONESC2H5 + H2Yog li4 → C6H
Vim tias cov txheej txheem npaj ua ke ntawm Paa, lub phenylacetic acid txoj kev tau maj mam dhau los ua lub ntsiab rau synthesizing phenacetin. Hom no yog npaj siv phenylacetic acid raws li cov khoom siv raw. Cov hauv qab no yog cov kauj ruam tshwj xeeb:
- Kauj Ruam 1: Cov tshuaj tiv thaiv hws ntawm phenylacetic acid thiab n {} Daim qauv siv roj ntsha
C6H5Ch2Cooh + C6H5Nh (co) ch3 → C6H5Ch2Nhcoch2C6H5 + H2O
- Step 2: Acetylation reaction of N - (phenylacetyl) - N '- methylaniline: N - (phenylacetyl) - N' - methylaniline undergoes acetylation reaction in acetic acid to produce N - (phenylacetyl) - n '{}}}} metylaniline acetate.
C6h5ch2nhoch 3 + ch3Co las2H → C6H5Ch2Nhcoch2C6H5Ch3Co las2H
- Kauj ruam 3: N - (phenylacetyl)}}}}}}}}} eceol mus sab esterification cov tshuaj tiv thaiv hauv carbon Tetrachloride los ua kom muaj phenacetin.
C6H5Ch2Nhcoch2C6H5Ch3Co las2H + C6H5Oh → c6H5OCONESC2H5 + C6H5Ch2Nhcoch2C6H5Ch3Co las2H
C6H5OCONESC2H5+ Ch3Co las2Kev nyuaj siab4H → C6H5Oc2H5+ Ch3Co las2H2Yog li4
Lub Tshawb Nrhiav Kev Tshawb Fawb ntawm Phenacetin
Xyoo 1873, cov kws tshawb fawb thawj zaug phenacetin los ntawm kev tawm tsam ntawm p} nitrophenol thiab glacial acetic acid catalyzed los ntawm tin. Txawm li cas los xij, cov khoom no tsis tau txais ntau lub sijhawm thaum lub sijhawm ntawd.
Ntau xyoo tom qab, xyoo 1887, muaj lub npe hu ua Acetophenetidin, tau qhia raws li kev noj tshuaj txo qis thiab mob nyem. Nws yog thawj qhov hluavtaws piv rau cov tshuaj thiab antipyretic tshuaj nyob hauv khw. Nws cov tshuab kev ua tau ntseeg tias muaj feem cuam tshuam nrog nws lub peev xwm los txo lub cev kub thiab txias hauv lub hlwb thiab tsim cov kev cuam tshuam loj.
Hmoov tsis zoo, phenacetin sai tau pom muaj cov kev mob tshwm sim tseem ceeb. Kev siv lub phenacetin ntev los yog ntau dhau ntawm phenacetin yuav ua rau muaj ntau yam teeb meem kev noj qab haus huv, suav nrog mob ntshav qab zib, hypeboxia, thiab mob cancer. Tshwj xeeb, kev siv phenacetin tau txuas rau ib qho kev nce qib loj hauv lub raum hauv xyoo 1950, coj mus rau nws qhov xwm txheej hauv ntau lub tebchaws.
Txawm hais tias nws cov drawbacks, qhov kev tshawb pom ntawm phenacetin yog qhov tseem ceeb hauv kev txhim kho ntawm cov chaw muag tshuaj niaj hnub. Cov kws tshawb nrhiav sai sai tias phenacetin tau yog metabolized nyob rau hauv lub cev los ua paracetamol (acetaminophen), uas muaj cov tshuaj zoo sib xws tab sis muaj tsawg dua kev phiv. Qhov no coj mus rau kev txhim kho thiab kev siv thoob plaws ntawm paracetamol yog kev nyab xeeb rau lwm txoj kev xav rau phenacetin.
Hauv cov ntsiab lus, thaum kev tshawb pom qhov kev tshawb pom qhov tseem ceeb hauv keeb kwm ntawm chaw muag tshuaj, nws cov kev mob tshwm sim tseem ceeb heev coj mus rau txoj kev hloov chaw zoo li cov kab mob Paracetamol. Zaj dab neeg ntawm phenacetin ua hauj lwm tam sim no ntawm qhov tseem ceeb ntawm kev sim nruj thiab txuas ntxiv tshawb fawb hauv kev tsim tshuaj.
Phenacetin, txawm hais tias tsis siv dav vim nws cov kev mob tshwm sim tsis zoo, ua lub luag haujlwm tseem ceeb hauv kev ua haujlwm ntawm cov tshuaj thiab antipyretics. Nws cov ntawv thov tau tsom rau kev ua kom mob thiab ua rau kev sib tw.
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Kev ntsuas kev nyab xeeb thiab cov cai tswj hwm nws ntau lawm, tuav, thiab pov tseg. Hauv cov ntawv thov khomob, cov phenacetin siv tau txwv vim nws lub zog carcinogenic. Keeb kwm, nws tau ua haujlwm ua analgesic thiab antipyretic, tab sis niaj hnub cov tshuaj tau hloov nws nrog kev hloov chaw nyab xeeb.
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Kev ua hauj lwm txeem rau phenacetin yuav tsum muaj tsawg, thiab cov neeg ua haujlwm tuav nws yuav tsum hnav hnab looj tes tsim nyog, suav nrog looj hnab looj tes, thiab ua pa lub ntsej muag. Cov chaw nyob qhov twg phenacetin yog ua tiav lossis khaws cia yuav tsum yog zoo- pa hluav taws xob los tiv thaiv cov kev phom sij lossis hmoov av.
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Pov tseg ntawm phenacetin khib nyiab yuav tsum muaj cov txheej txheem tshwj xeeb kom tsis txhob muaj kev sib kis ib puag ncig. Nws yuav tsum tau tswj hwm raws li hauv zos thiab thoob ntiaj teb tsim kev phom sij lossis pov tseg hauv cov av uas muaj kev phom sij tsim kev puas tsuaj.
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Kev tshawb fawb mus rau phenacetin tseem mus soj ntsuam cov peev xwm siv tau muaj feem cuam tshuam nrog kev saib xyuas kev nyab xeeb nyab xeeb kom ntseeg tau tias cov kev noj qab haus huv ntawm cov neeg koom thiab cov neeg tshawb fawb.
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Ntxiv mus, kev kawm txuj ci thiab kev cob qhia kev kawm yog qhov tseem ceeb rau kev pheej hmoo cuam tshuam nrog phenacetin nrog cov kws kho mob hauv kev kho mob, cov kws tshawb nrhiav, thiab cov neeg ua haujlwm. Kev Saib Xyuas Nruam thiab hloov kho tshiab ntawm kev nyab xeeb raws li kev pom tseeb tshaj plaws yog qhov tseem ceeb kom txo qis kev pheej hmoo ua kom muaj kev noj qab haus huv.
05
Hauv cov ntsiab lus, phenacetin, txawm hais tias nws tshwj xeeb cov khoom siv kho mob thiab keeb kwm kev kho mob, tam sim no feem ntau lees paub rau nws lub peev xwm carcinogenic. Kev ntsuas kev tiv thaiv kev nyab xeeb, suav nrog kev tswj hwm kev tswj hwm, thiab pov tseg, yog qhov tseem ceeb los tiv thaiv tib neeg kev noj qab haus huv thiab ib puag ncig los ntawm nws cov kev phom sij.
Phenacetin tau zoo nyob rau hauv kev tshem tawm ntau yam kev mob, los ntawm mob me me mus rau nruab nrab. Nws yog feem ntau siv los kho mob taub hau, mob hniav, coj khaub ncaws coj khaub ncaws, mob leeg, thiab lwm yam mob hnyav. Cov khoom analgesic ntawm phenacetin tau ntaus nqi mus rau nws lub peev xwm los inhibit prostaglandin synthesis, yog li txo qhov o thiab mob.
Ua npau taws
Ntxiv rau nws cov khoom analgesic,PhenacetinKuj tseem ua rau muaj kev kub taub hau. Nws txo qis lub cev kub teeb -}}}} Tshaj tawm hauv lub hlwb, cia lub cev kom txias nws tus kheej. Qhov no ua rau nws muaj cov tshuaj muaj txiaj ntsig rau kev kho rau cov kab ke ntau febrile.
Txawm li cas los xij, nws yog ib qho tseem ceeb kom nco ntsoov tias Phenacetin txoj kev siv tau ua rau muaj kev puas tsuaj loj xws li kev puas tsuaj loj xws li mob qog nqaij hlav. Raws li qhov tshwm sim, kev nyab xeeb dua zoo li Paracetamol (acetaminophen) tau tsim thiab tam sim no dav siv rau kev mob kom ua rau mob thiab ua kom haum.
Tshawb nrhiav ntawm phenacetin hmoov nyob rau hauv aqueous tau tsom rau nws tus cwj pwm, teebmeem, thiab kev kho mob hauv aqueous.
1. Kev coj cwj pwm ntawm phenacetin hauv thaj chaw aqueous
Raws li ib tus organic paug, phenacetin yuav cuam tshuam los ntawm ntau yam hauv cov aqueous thaj chaw, suav nrog solubility, thiab kev thauj khoom ruaj khov. Cov kev tshawb fawb tau pom tias phenacetin muaj lub solubility siab nyob rau hauv dej, uas txhais tau hais tias nws tuaj yeem nkag mus rau hauv lub cev ua paug. Ib qho ntxiv, phenacetin yuav yog degraded lossis hloov hauv cov dej lub cev los ntawm lub teeb, microbial kev ua haujlwm thiab lwm yam.
2. Cov teebmeem ntawm phenacetin rau ntawm cov khoom siv dej
Lub xub ntiag ntawm phenacetin nyob rau hauv ib puag ncig ib puag ncig tej zaum yuav ua rau muaj kev hem thawj rau cov tsiaj muaj sia thiab tib neeg kev noj qab haus huv. Tshwj xeeb, phenacetin tej zaum yuav muaj cov tshuaj lom neeg lom ntawm cov tsiaj muaj sia, cuam tshuam rau lawv txoj kev loj hlob, luam thiab muaj sia nyob. Nyob rau tib lub sijhawm, Phenacetin kuj tseem yuav dhau los ntawm cov khoom noj khoom noj thiab ua rau tsis ncaj ncees rau tib neeg kev noj qab haus huv. Tsis tas li ntawd, cov khoom ua tsis raws cai ntawm phenacetin kuj tseem tuaj yeem lom thiab xav tau kev saib xyuas.
3. Kev kho kev cuam tshuam ntawm phenacetin nyob rau hauv aqueous systems
Txhawm rau daws cov phenacetin hauv cov dej, cov kws tshawb nrhiav tau nqa tawm cov kev tshawb fawb ntawm ntau yam kev kho mob.
Advanced Oxidation Technology:
Advanced oxidation technology yog ib txoj kev zoo los ua kom degrade organic paug nyob rau hauv dej. Los ntawm kev tsim tawm oxidizing dawb radicals (piv txwv li, phenchoth radicals), lub phenacetin molecule tuaj yeem tawm tsam thiab degraded. Ntawm lawv, UV / chlorine system yog ib feem siv siv Advanced oxidation nrawm, tsis -} ecadation efficiency.
Biodegradation txoj kev:
Biodegradation yog ib txoj kev uas siv cov metabolic kev txiav txim ntawm cov kab mob me ntawm cov kab mob uas muaj teeb meem rau cov khoom siv tsis zoo. Rau qhov kev cuam tshuam ntawm phenacetin, qee cov kab mob me yuav muaj peev xwm ua rau nws. Txawm li cas los xij, kev ua tau zoo ntawm cov biodarration txoj hauv kev yuav cuam tshuam los ntawm ntau yam kev tuav dag zog, kub thiab sludge rov qab piv. Yog li, kev ua kom zoo dua ntawm kev ua kom muaj kev cuam tshuam cov kev mob yuav tsum tau txhawm rau txhim kho kev ua kom muaj kev txuag hluav taws xob.
Adsorption txoj kev:
Adsorption yog ib txoj kev uas siv cov adsorption ntawm adsorbents (piv txwv li, actins actab, resins, thiab lwm yam) kom tshem tawm cov etoric teeb meem los ntawm dej. Txawm hais tias tus qauv adsorption feem ntau tsuas yog tsim nyog rau kev kho cov kev ua kom zoo ntawm phenacetin effluent, nws tuaj yeem siv los ua pretrice kev ua haujlwm hauv qee kis.
Membrane Sib Cais Qauv:
Membrane sib cais yog ib txoj kev uas siv cov kev xaiv permeability ntawm ib semi- permricane los cais cov organic los ntawm dej. Txawm li cas los xij, txoj kev sib cais membrane yuav xav tau kev ua haujlwm siab thiab tu cov nyiaj txiag, yog li nws cov nyiaj txiag thiab kev ua tau xav tau los ntawm kev siv tau.
Hauv cov ntsiab lus, cov kev tshawb fawb ntawm Phenacetin hmoov hauv cov dej system yog cov ntsiab lus tseem ceeb thiab tseem ceeb. Los ntawm -} qhov tob nrhiav kev coj tus cwj pwm, nws tuaj yeem muab kev pab kho kom muaj zog rau kev tiv thaiv ntawm cov dej ib puag ncig thiab tib neeg kev noj qab haus huv.
Dab tsi yog qhov kev ceev faj rau kev siv cov compound no?
- Ua raws li cov lus qhia kho mob: Thaum siv cov tshuaj siv, nws yog qhov tsim nyog kom ua raws li cov kws kho mob cov lus qhia thiab siv tshuaj raws li kev pom zoo thiab txoj kev siv kev siv. Tsis txhob nce ntau npaum li cas lossis hloov cov txheej txheem siv ntawm koj tus kheej kom tsis txhob muaj kev pheej hmoo ntawm cov kev mob tshwm sim.
- Them sai sai rau cov tshuaj sib cuam tshuam: cov tshuaj no yuav cuam tshuam nrog lwm cov tshuaj thaum siv hauv kev sib xyaw ua ke, cuam tshuam rau kev ua tau tshuaj noj, cov kev ua tau zoo me, thiab cov txheej txheem excretion. Yog li ntawd, thaum siv, nws yog ib qho tsim nyog los them sai sai rau kev sib cuam tshuam nrog lwm cov tshuaj. Zam kev siv tshuaj uas yuav ua rau muaj tshuaj cuam tshuam, xws li tshuaj antipyricity thiab cov tshuaj yuav tsum tau siv ntau cov tshuaj yuav tsum tau siv ib qho tshuaj kho mob lossis kws muag tshuaj rau cov lus qhia.
- Saib xyuas cov kev cai lij choj: thaum siv, qhov tshwm sim ntawm kev cuam tshuam tsis zoo yuav tsum muaj kev soj ntsuam. Thaum tsis pom cov tsos mob tshwm sim, cov tshuaj yuav tsum nres tam sim ntawd thiab kho mob saib xyuas. Nyob rau tib lub sijhawm, daim siab tsis tu ncua thiab lub raum ua haujlwm yuav tsum tau ua kom pom kom sai thiab daws teeb meem lub raum thiab lub siab puas.
- Tsis txhob muaj ntev - lub sij hawm los yog siab {1} {} {{{{{-} Kev siv tau siv. Yog tias muaj ntev -}}}}}}}}}}}}}} Kev siv tshuaj yeeb thiab analgesic tshuaj yuav tsum muaj, lwm yam kev nyab xeeb thiab lwm txoj kev xaiv tau zoo yuav tsum tau txiav txim siab.
- Ua tib zoo saib cov tshuaj hauv chaw noj tshuaj: Cov hmoov no yuav tsum tau muab cia rau hauv qhov chaw qhuav, txias, muaj qhov cua zoo, kom deb ntawm lub hnub ci ncaj qha thiab kub. Nyob rau tib lub sijhawm, nws yuav tsum tau kom paub tseeb tias cov ntim tshuaj yog lawm thiab pub dawb los ntawm noo noo, paug, lossis piam sij.
- Nkag siab cov ntaub ntawv siv tshuaj: ua ntej siv, ua tib zoo nyeem cov lus qhia tshuaj kom nkag siab cov khoom xyaw, kev qhia, thiab cov kev cuam tshuam, thiab lwm yam ntaub ntawv ntawm cov tshuaj. Yog tias koj muaj lus nug, thov sab laj nrog kws kho mob lossis kws muag tshuaj rau cov lus qhia.
- Ua raws cov lus qhia noj tshuaj: Thaum siv, cov lus qhia hauv kev noj tshuaj, tsis txhob raug muab rau cov kws kho mob los kho cov phiaj xwm kho.
Cim npe nrov: Phenacetin hmoov uas 62-44-2, cov neeg muab khoom, chaw tsim khoom, Hoobkas, lag luam Wholesale, yuav, nqe, loj, loj, rau muag