Pure Vitamin B12 Powder CAS 68-19-9

Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm ntshiab vitamin b12 hmoov cas 68-19-9 nyob rau hauv Suav teb. Txais tos rau cov lag luam wholesale zoo siab ntshiab vitamin b12 hmoov cas 68-19-9 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.

Ntshiab vitamin B12 hmoov, raws li ib tug sib sib zog nqus liab, heev hygroscopic crystalline tshuaj, tau txais nws cov xim los ntawm nws core qauv - divalent cobalt ion ua hauj lwm nyob rau hauv nruab nrab ntawm lub cobalt 啉 nplhaib. Cov yam ntxwv no ua rau nws yog ib qho ntawm ob peb cov vitamins nrog cov xim txawv. Los ntawm qhov kev xav ntawm bioinorganic chemistry, nws yog qhov loj tshaj plaws thiab feem ntau cov vitamin molecule nyob rau hauv cov xwm, thiab tsuas yog paub cov organic organic hlau compound. Nws cov khoom lag luam yuav luag tag nrho nyob ntawm microbial fermentation (tsuas yog siv cov kab mob xws li Corynebacterium pseudoadriani), es tsis yog tshuaj synthesis. Cov txheej txheem no ingeniously circumvents qhov kev sib tw daunting ntawm tag nrho cov synthesis, ua rau nws ib yam khoom ruaj khov heev. Nyob rau hauv nws daim ntawv ntshiab, nws ruaj khov heev nyob ntawm ib puag ncig: nws yog rhiab heev rau lub teeb, oxygen, thiab pH qhov tseem ceeb. Tshwj xeeb tshaj yog nyob rau hauv cov tshuaj aqueous, oxidation -txo lub xeev ntawm cobalt ion hloov sai, ua rau poob ntawm lom lom. Yog li ntawd, kev khaws cia ntawm nws daim ntawv hmoov yog ib qho kev tshawb fawb me me, yuav tsum tau nruj anaerobic, lub teeb- pov thawj, thiab qis- qhov kub thiab txias, uas yog deb tshaj li cov khoom siv vitamin. Qhov no qhia txog qhov tsis muaj zog thiab tshuaj lom neeg tshwj xeeb ntawm qhov no raws li qhov tshwj xeeb "hlau coenzyme".

Kev kho mob yam:

 

① Siv los kho thiab tiv thaiv tsis muaj vitamin B12.
② Siv rau kev tiv thaiv ntawm anemia tshwm sim los ntawm vitamin B12 deficiency nyob rau hauv cov neeg mob nrog gastric resection los yog malabsorption syndrome.
③ Siv los ntxiv qhov kev thov ntau ntxiv rau vitamin B12 los ntawm kev noj cov kab mob, hyperthyroidism, cev xeeb tub, pub niam mis, thiab lwm yam.
④ Khoom noj khoom haus thiab cev xeeb tub anemia.

 

⑤ Anemia tshwm sim los ntawm Taenia solium.
⑥ Cov kab mob siab ua haujlwm tsis zoo.
⑦ Radiation induced leukopenia.
⑧ Mob paj hlwb, mob leeg, mob pob qij txha.
⑨ Peripheral neuritis, peripheral paj hlwb tuag tes tuag taw.
⑩ Tus txha caj qaum o, txha caj qaum degeneration.

Pub additives:

Pure vitamin b12 hmoovyog ib qho tseem ceeb micronutrients rau kev loj hlob ntawm lub cev. Cov nroj tsuag tsiaj feem ntau-raws li pub tsis muaj vitamin B12, uas yog tsim los ntawm cov kab mob hauv plab hnyuv thiab ntxiv rau sab nraud. Txhawm rau kom ua tau raws li cov kev xav tau ntawm cov vitamins tsiaj, nws yog ib qho tsim nyog yuav tsum tau ntxiv cov vitamin additives.
Qhov tshwm sim tseem ceeb ntawm vitamin B12 tsis txaus nyob rau hauv cov tsiaj tsis ruminant xws li npua thiab qaib yog kev loj hlob thiab kev loj hlob raug ntes, thiab ob peb tus npua kuj tuaj yeem ua rau mob ntshav liab ntshav liab. Tsis tas li ntawd, nws tseem tuaj yeem txo qhov hatching tus nqi ntawm qaib thiab tus menyuam yug ntawm npua. Cov tsos mob ntawm kev tsis txaus muaj xws li tsis qab los noj mov, kev loj hlob raug ntes, yooj yim anemia, thiab thaum mob hnyav, cov tsos mob ntawm lub paj hlwb.
Pub vitamin B12 tuaj yeem txhawb kev loj hlob thiab kev loj hlob ntawm cov nqaij qaib, tshwj xeeb tshaj yog cov nqaij qaib thiab cov tsiaj nyeg.

Yuav siv tau rau:

① Kev loj hlob thiab ntshav ntshav los ntawm qhov tsis muaj vitamin B12 hauv npua thiab qaib;
② Localized emaciation nyob rau hauv nyuj thiab yaj nyob rau hauv qhov chaw tsis muaj cobalt;
③ Tsis yog kev kho mob tshwj xeeb ntawm neuritis, neuralgia, thiab lwm yam;
④ Txhim kho qhov kev siv ntawm cov protein pub;
⑤ Kev yug tsiaj ntawm tsiaj nyeg;
⑥ Kev kho cov qe ntses los yog kib nrog B12 tov tuaj yeem txhim kho lawv txoj kev kam rau cov tshuaj lom xws li benzene thiab cov hlau hnyav hauv dej.

Lwm yam:

① Khoom noj khoom haus additives
② Siv tau los ua zaub mov xim: xws li nqaij npua, hnyuv ntxwm, ice cream, ntses ntses.
③ Siv rau cov tshuaj pleev ib ce, xab npum, tshuaj txhuam hniav, thiab lwm yam., nws kuj tseem siv tau rau kev tiv thaiv tsw hauv chav dej, tub yees, qhov ncauj kab noj hniav, thiab lwm yam, kom tshem tawm cov ntxhiab ntawm sulfides thiab aldehydes.

Detoxification ntawm huab cua pollutants:

Cov kws tshawb fawb los ntawm University of Manchester, UK, tau ua qhov tseem ceeb hauv kev tshawb fawb 15 xyoo. Lawv cia siab tias qhov txiaj ntsig no yuav txhawb kev tshawb fawb thiab txhim kho txoj hauv kev zoo los tshem tawm cov pa phem phem, xws li polychlorinated biphenyls (PCBs) thiab dioxins. Txoj kev tshawb no, luam tawm nyob rau hauv phau ntawv journal Nature, qhia meej tias qee yam kab mob txo cov co toxins ntawm cov pa phem.
Pab pawg tshawb fawb los ntawm Biotechnology Research Institute ntawm University of Manchester tau tshawb xyuas tias qee yam kab mob hauv lub cev txo qis cov tshuaj lom thiab ua rau lub neej luv ntawm cov pa phem loj.

Xib fwb David Reese piav qhia tias, "Peb twb paub lawm tias qee cov pa phem tshaj plaws muaj halogen atoms, thiab feem ntau cov kab mob lom tsis paub yuav ua li cas cov molecules no. Txawm li cas los xij, qee cov kab mob tuaj yeem siv cov vitamin B12 tshem tawm cov halogen atoms.

Nws paub tiasntshiab vitamin b12 hmoovyog ib coenzyme ntawm ntau mutases, xws li methyl aspartic acid mutase uas catalyzes hloov dua siab tshiab ntawm Glu rau methyl Asp, thiab methyl malonyl CoA mutase uas catalyzes hloov dua siab tshiab ntawm methyl malonyl CoA rau succinyl CoA. B12 coenzyme kuj koom nrog kev hloov pauv ntawm cov tshuaj methyl thiab lwm cov pa roj carbon monoxide.
B12 feem ntau pom muaj nyob hauv cov nqaij, thiab taum pauv thiab qee cov tshuaj ntsuab hauv cov nroj tsuag kuj muaj B12. Cov kab mob hauv plab tuaj yeem tsim cov B12, yog li nws feem ntau tsis muaj. Txawm li cas los xij, B12 yog ib qho vitamin uas yooj yim tsis muaj rau cov neeg uas muaj kab mob plab thiab ib qho tseem ceeb rau kev tsim cov qe ntshav liab. Yog tias tsis muaj mob hnyav, nws tuaj yeem ua rau mob ntshav qab zib.

Vitamin B12 yog dav nyob rau hauv cov zaub mov tsiaj. Thiab nws daim ntawv tsis tuaj yeem nqus los ntawm tib neeg lub cev. Tsis tas li ntawd, vitamin B12 tseem yog cov vitamin nkaus xwb uas muaj cov zaub mov tseem ceeb, tshwm liab vim nws cov ntsiab lus cobalt, tseem hu ua liab vitamin, thiab yog ib qho ntawm ob peb xim vitamin. Txawm hais tias vitamin B12 belongs rau pawg B ntawm cov vitamins, nws tuaj yeem khaws cia rau hauv daim siab. Tom qab tso nws lub peev xwm cia, nws yuav siv sijhawm ntau tshaj rau lub hlis kom pom cov tsos mob ntawm qhov tsis txaus. Tib neeg lub cev xav tau cov vitamin B12 tsawg heev, thiab ntev npaum li kev noj haus zoo li qub, yuav tsis muaj qhov tsis txaus. Ib tug me me ntawm cov neeg uas muaj kev nqus tsis zoo yuav tsum tau saib xyuas tshwj xeeb.

Kev nqus metabolism:

 

Vitamin B12 hauv cov zaub mov khi nrog cov protein thiab nkag mus rau tib neeg lub plab zom mov. Raws li kev ua ntawm gastric acid, pepsin, thiab trypsin, vitamin B12 raug tso tawm thiab khi rau glycoprotein intrinsic factor (IF) secreted los ntawm lub plab phab ntsa hlwb. Cov vitamin B12 IF complex yog absorbed nyob rau hauv lub ileum. Qhov khaws cia ntawm cov vitamin B12 tsawg heev, txog 2-3mg hauv daim siab. Feem ntau yog tawm los ntawm cov zis, nrog rau qee qhov tso tawm los ntawm cov kua tsib.

Feem ntau muaj ob:

 

① Raws li ib tug cofactor ntawm methyltransferase, nws koom nyob rau hauv lub synthesis ntawm methionine, thymine, thiab lwm yam, xws li converting methyltetrahydrofolate rau tetrahydrofolate thiab hloov cov methyl pawg mus rau methyl receptor (xws li homocysteine), ua rau methyl receptor ivydine los yog methyl asder. methylhomocysteine ​​). Cov tshuaj tiv thaiv yog qhia nyob rau hauv daim duab. Yog li, vitamin B12 tuaj yeem txhawb nqa cov protein biosynthesis thiab cuam tshuam rau kev loj hlob thiab kev loj hlob ntawm cov menyuam mos thiab menyuam yaus thaum tsis muaj.

 

② Tiv thaiv kev hloov pauv thiab khaws cov folate hauv cov hlwb. Thaum cov vitamin B12 tsis txaus, cov ntsiab lus folate hauv tib neeg cov qe ntshav liab tsawg, thiab cov folate khaws cia hauv daim siab txo. Qhov no tej zaum yuav muaj feem xyuam rau vitamin B12 tsis txaus, uas ua rau nyuaj rau kev hloov methyl pawg los ntawm homocysteine ​​mus rau methionine. Cov pab pawg methyl sib sau ua ke hauv cov hlwb, ua rau cov khoom khaws cia ntawm tetrahydrofolate hauv cov hlwb vim tias tetrahydrofolate nyiam khi nrog cov methyl pawg los tsim cov methyltetrahydrofolate, uas yog synthesizes polyglutamic acid.

Pure vitamin b12 hmoovthiab folate deficiency ua rau txo qis hauv thymidine nucleotides, qeeb DNA synthesis, thiab nce intracellular uridine deoxyribonucleotide (dUMP) thiab deoxytriphosphate uridine (dUTP). Qhov txo qis ntawm thymidine deoxyribonucleoside triphosphate (dTTP) ua rau muaj kev sib koom ua ke ntawm uracil rau hauv DNA, ua rau cov DNA tawg, qeeb DNA rov ua dua, thiab lub sij hawm ntev nuclear faib (S thiab G1 theem). Raws li qhov tshwm sim, lub nucleus loj dua li qub, thiab cov chromatin nucleus zoo li xoob dot network, tsis muaj concentration. Txawm li cas los xij, tsis muaj teeb meem tseem ceeb rau RNA thiab protein synthesis hauv cytoplasm. Nrog ncua kev faib tawm nuclear thiab nce kev sib txuas, cov qe ntshav loj tau tsim nrog lub cev loj ntawm tes, asynchronous nuclear cytoplasmic txoj kev loj hlob, xoob nuclear chromatin, thiab kev hloov pauv hauv li ntawd -hu ua "plasma hluas nucleus". Cov kev hloov loj heev yog qhov tseem ceeb tshaj plaws thiab cov yam ntxwv ntawm cov qe ntshav liab tsis paub qab hau, lub npe hu ua cov qe ntshav liab loj heev. Cov kev hloov loj heev hauv cell morphology kuj tuaj yeem pom hauv granulocytes, megakaryocytes, thiab txawm tias qee lub cell proliferating somatic. Cov qe ntshav liab megaloblastic no ua rau muaj kev puas tsuaj hauv cov pob txha pob txha, ua rau cov qe ntshav liab tsis zoo. Thaum kawg, nws ua rau cov ntshav liab tsis txaus suav thiab tshwm sim raws li cov tsos mob ntshav qab zib.

 

Nws yog los txhim kho tus nqi siv ntawm folic acid. Nyob rau hauv tus txheej txheem ntawm synthesizing methionine (synthesized los ntawm homocysteine ​​​​) thiab choline ua ke nrog folic acid los tsim purine thiab pyrimidine, cyanocobalamin methyl precursor tshuaj xws li methylcobalamin thiab coenzyme B12 yog synthesized, uas koom rau hauv cov txheej txheem methylation ntawm ntau lub tebchaw tseem ceeb. Thaum cov vitamin B12 tsis txaus, kev ua haujlwm ntawm kev hloov methyl pawg los ntawm methyltetrahydrofolate txo qis, ua rau folate ua tsis tau thiab ua rau folate deficiency.Nws txhawb kev loj hlob thiab loj hlob ntawm cov qe ntshav liab. Hloov methylmalonyl CoA rau hauv succinyl CoA, uas koom nrog hauv lub voj voog tricarboxylic acid. Succinyl CoA koom nrog hauv kev sib xyaw ntawm heme.

 

Nws yog los tswj cov metabolism thiab ua haujlwm ntawm paj hlwb myelin sheaths. Tsis muaj vitamin B12 tuaj yeem ua rau muaj kev puas tsuaj rau lub paj hlwb, tus txha caj qaum degeneration, thiab cov tsos mob ntawm kev puas siab puas ntsws loj. Vitamin B12 deficiency tuaj yeem ua rau peripheral neuropathy. Qhov tshwm sim thaum ntxov ntawm cov vitamin B12 tsis muaj peev xwm hauv cov menyuam yaus yog qhov txawv txav, kev qhia tsis zoo, tsis tshua muaj tshwm sim, thiab thaum kawg anemia.

Vitamin B12 kuj koom nrog hauv kev sib txuas ntawm deoxyribonucleic acid (DNA). Metabolism ntawm cov rog, carbohydrates, thiab cov protein ua kom cov synthesis ntawm nucleic acids thiab proteins.

1. Cov khoom sib xyaw thiab daim ntawv:
Cov khoom no feem ntau yog hais txog siab -purity methylcobalamin los yog cyanocobalamin hmoov, uas yog daim ntawv ntxiv ntawm vitamin B12.
2. Cov teebmeem tseem ceeb:
Txhawb nqa lub zog metabolism, tswj cov paj hlwb noj qab haus huv, thiab txhawb kev tsim cov qe ntshav liab.
3. Muaj xwm txheej:
Haum rau cov neeg tsis noj nqaij, cov neeg laus, lossis cov tib neeg uas muaj kev zom zaub mov tsis zoo, thiab siv los ntxiv cov B12 uas yuav tsis muaj kev noj haus txhua hnub.

Cim npe nrov: ntshiab vitamin b12 hmoov cas 68-19-9, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom