Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab lwm tus neeg ntawm 2,3-difluorophenol CAS 6418-38-8 nyob rau hauv Suav teb. Txais tos rau kev lag luam wholesale ntau qhov zoo 2,3-difluorophenol CAS 6418-38-8-8 Kev muag khoom ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
2,3-difluorophenolyog cov organic compound nrog cov tshuaj noj tshuaj c6h4f2o. Nws zwm rau pawg ntawm cov duab uas muaj ntxhiab, cov phenols tshwj xeeb hloov nrog ob cov tshuaj fluorine atoms. Cov Taw Qhia Txog Fluorine atoms rau hauv phenol qauv kev hloov pauv nws cov tshuaj lom neeg thiab lub cev lub cev. Fluorine yog cov khoom hluav taws xob feem ntau, uas ua kom muaj kev sib txuam ntawm cov molecuent thiab cuam tshuam nws cov kev sib txuas lus sib xyaw. Yog li ntawd, nws qhia hloov solubility, melting point, thiab boiling point piv rau unsubstituteduteuteduteuteduteduteduteuteduteuteduteduteduteutected phenol.
Qhov no compound nrhiav cov ntawv thov hauv ntau thaj teb vim nws cov yam ntxwv tshwj xeeb. Hauv kev lag luam kws tshuaj, nws ua haujlwm ua cov tshuaj nruab nrab hauv kev sib xyaw ua ke tuaj yeem hloov kho cov tshuaj lom neeg thiab cov khoom siv tshuaj ntawm cov khoom lag luam ntawm cov khoom kawg. Tsis tas li ntawd, nws tau siv nyob rau hauv kev tsim cov agochemicals, polymers, thiab dyes, tau txiaj ntsig los ntawm nws cov kev ua kom zoo thiab ruaj khov.
Ntxiv mus, cov kws tshawb nrhiav feem ntau ntiav nws ua lub tsev ua hluav taws xob hauv cov organic synthesis, siv kom zoo dua ntawm cov tshuaj tiv thaiv fluoricated ntau zaus. Nws lub luag haujlwm hauv kev txhim kho cov ntaub ntawv tshiab thiab ua haujlwm molecules underscores nws qhov tseem ceeb hauv kev tshawb fawb.
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Tshuaj Cov Qauv |
C6H4F2O |
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Muaj pes tsawg leej |
130.02 |
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Molecular hnyav |
130.09 |
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m/z |
130.02 (100.0%), 131.03 (6.5%) |
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Kev Ntsuam Xyuas |
C, 55.40; H, 3.10; F, 29.21; O, 12.30 |
Tshuaj Txha
Hauv kev siv tshuaj chemistry,2,3-difluorophenolMuaj nuj nqis heev raws li nws pabcuam ua qhov tseem ceeb nyob rau hauv cov synthesis ntawm ntau tus kws tshuaj. Cov Taw Qhia Txog Fluorine atoms rau hauv cov rings, xws li hauv Philol Derivatives, tuaj yeem cuam tshuam rau lub cev, tshuaj lom neeg ntawm cov khoom muaj xyoob ntoo.
Qhov muaj kev sib txuam ntawm cov tshuaj fluorine atoms tuaj yeem cuam tshuam rau Liplophilicity, thiab kev ua haujlwm ntawm roj ntsha, ua rau lub tsev tseem ceeb hauv cov tshuaj chemistry.
Cov tshuaj fluorine hloov pauv yuav ua kom cov lipophilicity (rog - kev hlub ntawm cov xwm txheej) ntawm cov tebchaw. Qhov no yog qhov tshwj xeeb ntawm cov tshuaj tsim raws li nws tuaj yeem txhim kho kev nqus cov tshuaj tsim, kev faib tawm, cov metabolism, excepeties ntawm cov neeg sib tw noj tshuaj. Txhim kho Lipophilicity feem ntau ua rau pom zoo dua Membrane permeability thiab yog li txhim kho bioavailability.
Fluorine atoms tuaj yeem ruaj khov lub nplhaib muaj ntxhiab tiv thaiv metabolic tsis saib xyuas. Qhov no tuaj yeem ua rau muaj kev sib txuas lus ntev dua ib nrab - Nyob hauv vivo cov neeg sawv cev uas yuav tsum tau muaj cov kev ua tau zoo hauv lub cev ncua sij hawm.
Muaj cov tshuaj fluorine kuj tseem tuaj yeem hloov cov roj ntsha kev ua haujlwm ntawm ib qho kev sib txuas. Fluorinated derivatives feem ntau ua rau muaj kev lom zem txhim kho ib qho kev sib kho ntawm cov phiaj xwm roj ntsha xws li cov enzymes, receptors, thiab ion raws. Qhov no tuaj yeem ua rau muaj zog thiab cov tshuaj xaiv nrog txo qis- phiaj xwm.
Cov tshuaj fluorine hloov tuaj yeem qhia cov tsis sib haum. Qhov kev txwv tsis pub muaj txiaj ntsig muaj txiaj ntsig zoo hauv kev ruaj khov ntawm cov kev sib tw tshwj xeeb, yog li txhim kho txoj kev ua tau zoo thiab xaiv cov tshuaj.
Cov tshuaj fluorine tuaj yeem ua tus biocostere rau hydrogen, hydroxyl, lossis lwm pab pawg. Qhov no txhais tau tias fluorinated tebchaw tuaj yeem ua rau cov kev ua haujlwm ntawm kev tsis yog {{}} Cov tshuaj fluorinated thaum muab cov khoom lag luam txhim kho.
Hauv cov ntsiab lus, cov tshuaj fluorine - hloov cov qauv phenol muab cov tshuaj pleev xim rau cov tshuaj nrog cov tshuaj nrog cov khoom siv. Nws lub peev xwm los hloov cov lipophilicity, thiab kev ua haujlwm roj ntsha ua rau nws lub tsev tsis tseem ceeb hauv kev siv tshuaj chemical. Cov kws tshawb fawb qeverage cov khoom tsim no rau tsim thiab tsim cov kev tsim tawm cov kev xav tau zoo, thaum kawg pab txhawb rau kev nce qib hauv kev kho mob hauv kev kho mob.
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Cov Qauv Tshuaj Tua Tshuaj
Qhov no sib xyaw pom cov ntawv thov ntawm cov tshuaj tua kab vim nws cov tshuaj fluorine hloov cov roj ntsha thiab ib puag ncig kev nyab xeeb ntawm cov tshuaj tua kab. Nws tuaj yeem siv tau los synthesize tshuaj tua kab nrog kev txhim kho kev ua tau zoo thiab txo qis kev cuam tshuam ib puag ncig.
Fluorine hloov chaw tuaj yeem hloov kho hluav taws xob thiab cov teeb meem ntawm cov molecule, uas tuaj yeem ua rau kev txhim kho kev sib tw ntawm kev muaj peev xwm ntawm cov kab mob biological. Qhov no tuaj yeem ua rau cov tshuaj tua kab nrog lub zog loj dua thiab xaiv tau, lub ntsiab lus lawv ua rau muaj kev phom sij tsawg thaum tsis muaj peev xwm tsawg heev rau qhov tsis {
Cov lus qhia txog cov tshuaj fluorine tuaj yeem siv tshuaj tua kab mob molecules tawm tsam kev ua haujlwm rau ib puag ncig xws li hnub ci, ya raws, thiab microbial, thiab microbial kev ua si. Qhov no ua tau ruaj khov ruaj khov tuaj yeem txhais rau hauv kev tiv thaiv kev tiv thaiv ntev npaum li cas nrog kev tswj hwm ntau yam zaus.
Tshuaj tua kab hluavtaws siv hluav taws xob siv nws tuaj yeem nthuav tawm txhim kho kev ua tau zoo vim lawv lub cev ua kom zoo thiab tshuaj lom neeg. Qhov no tuaj yeem ua rau cov tswv yim tua hluav taws muaj txiaj ntsig ntxiv, txo qis kev muaj nuj nqis ntau yam kom muaj tshuaj tua kab mob ib puag ncig.
Txawm hais tias lawv tau tshuaj tua kab mob fluably, fluorinated tshuaj tua kab uas tau tsim los siv nws tseem tuaj yeem tsim qauv los ua rau muaj kev yooj yim nyob hauv ib puag ncig ib puag ncig. Qhov sib npaug no ntawm kev ruaj khov thiab kev tsis tu ncua yog qhov tseem ceeb rau kev tsim cov tshuaj tua kab nrog kev txo cov kev cuam tshuam ib puag ncig. Ib qho ntxiv, qhov ntau dua potency ntawm cov tshuaj tua kab no tuaj yeem txhais tau tias tus nqi thov dua tshiab, ntxiv kev taug ko taw hauv ecological.
Hauv cov ntsiab lus, nws ua haujlwm ua qhov muaj txiaj ntsig zoo nyob rau hauv cov hluavtaws ntawm kev tua tshuaj tua kab nrog kev txhim kho kev ua tau zoo thiab txo cov kev cuam tshuam ib puag ncig. Nws cov tshuaj fluorine hloov cov kev cuam tshuam nrog kev ua haujlwm ntawm roj ntsha thiab ib puag ncig kev ruaj khov, ua rau nws cov cuab yeej tseem ceeb hauv kev txhim kho kev daws teeb meem kev nyab xeeb ntau. Los ntawm kev siv cov khoom siv no, cov kws tshawb nrhiav tuaj yeem tsim cov tshuaj tua kab uas muaj txiaj ntsig zoo thiab ua rau muaj kev phooj ywg zoo dua qub.
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Ua Kua Ua Si Crystal Ntaub Ntawv
Raws li kev tivthaiv hauv cov ntaub ntawv ua kua crystal, nws pab txhawb rau kev txhim kho cov txheej txheem thev naus laus zis tshaj lij. Nws cov khoom lag luam tshwj xeeb ua rau nws tsim nyog rau siv hauv cov kua siv lead ua kua, qhov uas nws pab txhim kho cov zaub ua haujlwm thiab kev ruaj khov.
Cov roj fluorine atom hloov cov molecule cov khoom siv hluav taws xob thiab lub cev, muab cov qauv tshwj xeeb hauv cov kua muaj kua roj crystal. Cov tshuaj fluorine no tuaj yeem cuam tshuam nrog cov molecular ntim, kev sib cuam tshuam, thiab kev cuam tshuam hauv cov kua crystal theem, ua rau kom ua tau zoo.
Los ntawm kev sib txuam nws rau cov ntaub ntawv ua kua, cov tuam ntxhab tuaj yeem ua tiav kev txhim kho cov zaub ua yeeb yam. Qhov no suav nrog:
- Siab dua sib piv: Cov tshuaj fluorine atoms yuav txhim kho cov khoom kho qhov muag ntawm cov kua muaj kua, ua rau muaj ntau dua qhov xim thiab ntau dua cov xim.
- Cov Sijhawm Teb: Cov qauv hloov kho molecular tuaj yeem ua rau hloov nrawm dua, uas yog qhov tseem ceeb rau kev txo cov lus qhia plooj plooj thiab txhim kho tag nrho cov kev teb ntawm cov zaub.
- Txhim kho qhov saib cov ces kaum: Kev sib txuam muaj peev xwm pab tau kom nthuav dav cov ces kaum, ua rau cov zaub pom tau ntau dua los ntawm cov kev xav sib txawv.
Ua kua Crystal qhia txog qhov uas nws tuaj yeem nthuav tawm ruaj khov nyob rau hauv ntau qhov chaw ib puag ncig. Fluorine atoms pab txhawb rau Molecule qhov tsis kam mus rau kev cuam tshuam rau kev ua phem, kom meej cov kua siv lead ua cov khoom siv tau tswj hwm nws lub sijhawm ntev dua. Qhov kev ruaj khov no yog qhov tseem ceeb rau kev tswj cov kev ua tau zoo sib xws dhau lub neej ntawm lub cuab yeej.
Cov tshuaj tiv thaiv tsis zoo
2,3-difluorophenol yog cov tshuaj lom fluoricated nrog cov tshuaj lom neeg c ₆ h ₄ f ₂ o thiab txoj kev molecular hnyav ntawm 130.09. Raws li nrab hauv daim duab tshuaj, tshuaj tua kab, thiab cov ntaub ntawv siv ua kua, nws cov ntawv thov koom nrog cov khoom siv ntau lawm thiab kev lag luam tsim kev lag luam thiab kev lag luam tsim kev lom zem. Vim tias cov lus qhia ntawm cov tshuaj fluorine atoms hauv cov qauv molecular, cov hluav taws xob hluav taws xob thiab kev faib tawm ntawm Phenol yog hloov. Thaum lub sijhawm no muaj cov tshuaj lom neeg tshwj xeeb, nws kuj yog cov kev pheej hmoo txaus ntshai.
Kev tiv thaiv kab mob kom zoo
Qhov ncauj toxicity
Kev sim cov ntaub ntawv qhia tau hais tias qhov ncauj LD50 (nruab nrab yog koob tshuaj (nruab nrab Thaum cov tsiaj noj cov koob tshuaj uas qee yam, nws yuav ua rau cov ntshav plab zom mov xws li kev qaug zog thiab raws plab, tsaug zog, ua rau tsis muaj mob. Piv txwv li, qhov ncauj koob tshuaj ntawm LD ₅₀ hauv nas yog kwv yees li 500mg / kg, ntsuas kev coj noj coj ua uas tsis tshua muaj neeg tuaj yeem ua rau neeg mob ntuav thiab lub plab zom mov.
Inhalation Toxicity
Thaum kev tsim khoom lossis siv, yog tias qhov cua tsis zoo ua rau muaj kev kub ntxhov ntau dhau ntawm cov aerosols lossis vapors, nqus pa tuaj yeem ua rau muaj mob huam. Cov tsos mob muaj xws li kev ua pa tawm hauv plab (hnoos, kev ua pa luv luv), taub hau taub hau, kiv taub hau kev pom zoo. Qhov kev sim ua kom pom tias lub nqus pa ntawm LC ₅₀ (ib nrab ntawm kev ua kom tuag taus) los ntawm cov nas tau hais tias nqus tau kev nqus tau muaj txoj kev pheej hmoo ua kom muaj kev pheej hmoo.
Daim tawv nqaij tiv toj toxicity
Sib cuag ncaj qha rau cov siab ntau ntawm 2,3-difluorophenol yuav ua rau cov tshuaj tiv thaiv tawv nqaij. Cov ntaub ntawv qhia tau tias thaum cov neeg ua haujlwm kov cov ntaub ntawv cov hnab looj tes uas tsis hnav cov tsos mob hauv zos, nrog rau cov tsos mob ntawm cov txheej txheem xws li kev kub ntxhov thiab nkees. Qhov no qhia tau tias thaum daim tawv nqaij tsis muaj xwm yeem cuam tshuam rau cov hlab ntshav thiab ua rau cov kev tawm tsam.
Daim tawv nqaij thiab qhov muag tsis zoo
Daim tawv nqaij voos
Cov nyhuv irritant ntawm 2,3-diamles Cov kev sim tsiaj pom tias tom qab thov 0.1ML ntawm thawj cov lus daws rau cov luav tawv nqaij rau 4 teev, uas tau tsim los rau edema (irritation index 2.0) Tom qab 24 teev. Hauv cov tib neeg mob, tus neeg teb xov tooj tsis ua haujlwm hnav cov khaub ncaws tiv thaiv tsis pub dhau 28 teev tom qab, taw qhia kev ncua sij hawm txhawb nqa.
Qhov muag
Kev ncaj qha qhov muag yog qhov siab tshaj plaws - kev pheej hmoo hom ntawm kev sib cuag. Cov kev sim tsiaj tau qhia tias tom qab 0.05ml ntawm cov kev daws teeb meem tau nqis mus rau hauv lub qhov muag luav, qhab nia 2.0) thiab cov kis tau tsis pub dhau 1 feeb. Hauv kev sib tsoo tib neeg, yog tias kev ntsuas cov neeg ua haujlwm txaws lawv lub qhov muag thiab yaug yaug qhov muag, lawv yuav tsum tau nrhiav kev kho mob thiab siv tshuaj tiv thaiv kev kho mob. Qhov no qhia tau tias nws cov nyhuv stimulating yuav ua rau kev puas tsuaj rau cov epithelium thiab ua rau pom kev ua ib ntus ib ntus.
Cim npe nrov: 2,3-difluorophenol CAS 6418-38-8-8, Cov chaw tsim khoom, chaw tsim khoom, chaw tsim khoom, yuav khoom, nqe, loj, rau muag