Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab lwm tus neeg ntawm 4-chloro-7-Azaindole CASE 550-28-3 hauv Suav teb. Txais tos rau kev lag luam wholesale ntau yam zoo 4-chloro-7-Azaindole CASE 55052-28-3 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
4-chloro-7-azaindoleyog ib qho tseem ceeb nitrogen - muaj cov ntxhiab heterocclic. Nws cov qauv tuaj yeem suav tias yog cov pa roj carbon atom ntawm Benzene lub nplhaib ntawm lub pob zeb ua haujlwm ntawm lub ntsej muag thiab cov pyrerrole thiab pyrorine thiab cov tshuaj canrorine atom yog txuas nrog txoj haujlwm 4 ntawm lub cev pob txha no. Cov txheej txheem kev hloov pauv no tau xaus rau nws nrog cov khoom siv tsis zoo, thiab cov khoom siv hluav taws xob tsis muaj peev xwm ua rau kev sib koom tes zoo li ob leeg cov khoom noj hydrogen zoo thiab cov hydrogen Daim ntawv lees txais, zoo heev txhim kho cov molecular lees paub thiab tus kheej - sib dhos muaj peev xwm. Yog li ntawd, cov compound no ua si tseem ceeb ntawm cov chaw tshuaj kho yeeb tshuaj, tshwj xeeb yog cov kws tshaj lij lossis cov qauv zoo tshaj plaws rau kev tsim cov tshuaj tiv thaiv tseem ceeb los txhim kho cov tshuaj tshiab; Ntxiv mus, nws tseem yog cov khoom siv hluavtaws tseem ceeb rau kev tsim cov khoom siv {} Cov khoom siv polymers, thiab cov kev tshawb fawb dav dav thiab cov kev tshawb fawb dav dav.
|
|
|
|
C.F |
C7h55Cln2 |
|
E.M |
152 |
|
M.W |
153 |
|
m/z |
152 (100.0%), 154 (32.0%), 153 (7.6%), 155 (2.4%) |
|
E.A |
C, 55.10; H, 3.30; Cl, 23.23; N, 18.36 |
Daim Ntawv Thov nyob rau hauv lub chaw ua tshuaj
4-Chloro-7-Azaindole, nrog cov tshuaj noj tshuaj c7h55cln2, yog ib qho tseem ceeb organic thiab kws tshuaj hauv nruab nrab. Feem ntau nws pom tias yog cov hmoov dawb lossis tawm dawb nrog qee yam tshuaj lom neeg thiab kev ruaj khov stability. Hauv cov txheej txheem tshuaj thiab tshuaj synthesis, feem ntau nws yog feem ntau siv los ua cov khoom siv pib lossis nruab nrab kom koom nrog ntau yam kev sib txuas lus sib txuas.
1. Khoom cua ntawm cov tshuaj tua kab mob
Nws kuj tseem siv tau rau synthesizing antibacterial. Cov tshuaj tua kab yog cov cuab yeej tseem ceeb rau kev kho kab mob ntawm cov kab mob sib kis, thiab ua rau cov kab mob sib kis tau los ntawm kev loj hlob thiab luam ntawm cov kab mob. Cov tshuaj no feem ntau muaj broad- spectrum antibacterial kev ua si thiab tuaj yeem tsom ntau cov kab mob rau cov kab mob sib txawv lossis cov kab mob bacteriostative.
Hauv cov txheej txheem txhim kho ntawm cov tshuaj tsim kho, uas yog ib qho nrab, nws tuaj yeem koom nrog ntau yam kev sib txawv los ua cov tshuaj tua kab mob sib txawv. Los ntawm kev tshuaj xyuas thiab ua kom zoo dua, cov tshuaj tua kab mob tshiab nrog kev ua haujlwm siab, tsis tshua muaj tshuaj lom, thiab dav}} spectrum cov tshuaj tua kab mob tuaj yeem tau txais.
2. Khoom cua ntawm cov tshuaj tiv thaiv kab mob
Ntxiv nrog rau anti - cov qog-} Cov qog thiab cov tshuaj tua kab, nws kuj tseem tuaj yeem siv rau cov tshuaj tua kab mob. Cov kab mob kis tau yog qhov teeb meem kev noj qab haus huv thoob ntiaj teb, thiab cov tshuaj tiv thaiv kab mob yog qhov tseem ceeb ntawm kev kho kab mob kis. Nws cov derivatives tuaj yeem ua tiav lub hom phiaj ntawm kev kho mob kis kab mob los ntawm kev cuam tshuam nrog cov txheej txheem kev sib tw thiab cov txheej txheem kab mob.
Hauv cov txheej txheem txhim kho, raws li cov khoom siv tshuaj tiv thaiv lossis cov khoom nruab nrab, lawv tuaj yeem koom nrog kev ua kom sib xyaw nrog cov tshuaj tiv thaiv kab mob. Cov lus teb no tau pom cov txiaj ntsig tseem ceeb hauv ob qho tib si hauv Vitro thiab Vivo kev sim, thiab yuav tsum tau ua neeg sib tw tseem ceeb rau cov tshuaj antiviral.
Nyob rau hauv biochemical reagents
4-Chloro-7-Azaindole, raws li ib qho tseem ceeb biochemical reagent, muaj kev siv tus nqi dav hauv kev tshawb fawb txog lub neej. Nws cov qauv tshuaj lom neeg thiab cov kev ua haujlwm tseem ceeb rau kev kawm ua cov kab mob ua si, thiab nkag siab cov metabolic txheej txheem ntawm cov muaj sia.
Raws li lub biovaterial rau kev tshawb fawb txog lub neej kev tshawb fawb
Nws tau siv thawj zaug ua ib lub biomaterial nyob hauv thaj teb ntawm biochemistry. Biom me los saib cov ntaub ntawv uas cuam tshuam nrog kev siv hluav taws xob thiab siv rau kev kuaj mob, kev kho mob, lossis kev txhim kho kev siv roj ntsha. Vim nws cov tshuaj tshwj xeeb, nws tuaj yeem simulate lossis cuam tshuam qee yam txiaj ntsig biochemical cov txheej txheem hauv kev kawm cov khoom muaj sia, cov metabolism hauv kev kawm, cov me nyuam kab mob.
Hauv kev tshawb fawb lub neej kev tshawb fawb, feem ntau nws yog feem ntau siv hauv kev sim ntawm tes kab lis kev cai. Cov cell yog cov chav nyob ntawm cov muaj sia nyob, thiab kawm lawv tus cwj pwm thiab cov yam ntxwv tseem ceeb heev rau kev nkag siab ntawm cov kab mob muaj sia. Nws tuaj yeem ua cov kev tswj hwm ntawm cov kws tshaj lij, pab cov kws tshawb fawb ntawm cov txheej txheem ntawm cov txheej txheem ntawm xov tooj ntawm tes, thiab hom ntawm xov tooj ntawm lub hlwb.
Ib qho ntxiv, nws kuj tseem siv tau los kawm cov teeb liab transductions kev hloov pauv ntawm cov muaj sia muaj sia. Kev hloov teeb liab yog ib qho tseem ceeb ntawm kev xa cov ntaub ntawv sib kis ntawm thiab tsis pub dhau cov kab mob muaj sia, uas cuam tshuam nrog ntau yam biomolecules thiab complex biochemical cov tshuaj tiv thaiv. Nws tuaj yeem cuam tshuam cov kev ua si ntawm cov phiaj xwm transdal transduction los yog enzymes hauv lub cev, yog li qhia cov txheej txheem thiab kev tswj hwm ntawm kev hloov teeb liab hauv lub cev.
Tsis tsuas yog nws siv los ua cov khoom siv txheeb rau lub neej science lub neej, tab sis nws kuj tseem tau dhau los ua kev tshawb tshuaj yeeb tshuaj vim nws cov kev ua tshwj xeeb. Kev nrhiav yeeb tshuaj yog ib txoj kev ua yeeb yam thiab cov kev nkag siab ntev uas cuam tshuam nrog kev nkag siab zoo ntawm cov kab mob muaj sia, thiab kev tshuaj ntsuam thiab ua kom zoo rau cov tshuaj sib tw.
Nws tuaj yeem siv los ua qhov muaj txiaj ntsig zoo hauv cov txheej txheem ntawm cov tshuaj pom kev ua yeeb yam los ua ke nrog cov chaw muag tshuaj uas muaj kev sib xyaw. Los ntawm kev hloov kho thiab hloov kho nws cov qauv tshuaj, cov qauv ntawm cov roj ntsha sib txawv tuaj yeem tsim tawm, uas tuaj yeem pom zoo ntxiv thiab ua kom zoo dua li cov tshuaj sib tw.
Piv txwv li, nws tuaj yeem siv los ua ke 7 - Azaindole derivatives, uas ua kom pom kev zoo, tshuaj tiv thaiv thiab lwm yam. Los ntawm kev kawm lawv lub twj siv tshuaj, peb tuaj yeem nkag siab txog kev nkag siab tob ntawm cov peev xwm thiab thov cov kev cia siab ntawm cov kab mob uas muaj feem xyuam.
Ib qho ntxiv, nws tseem tuaj yeem siv rau synthesizing cytokinin analogs. CyTokinins yog cov tshuaj hormones tseem ceeb uas tswj cov kab ke ntawm tes thiab sib txawv hauv kev muaj sia nyob hauv kev tswj hwm kev loj hlob thiab kev loj hlob ib txwm muaj. Los ntawm synthesizing cytokinin analogs, lawv cov haujlwm ntawm kev ua hauv Vivo tuaj yeem kawm tau, muab cov pov thawj tseem ceeb rau kev txhim kho kev tshiab ntawm kev kho cov qauv thiab cov tshuaj.
Nws tseem ua lub luag haujlwm tseem ceeb hauv kev kawm ntawm cov metabolic txheej txheem hauv cov muaj sia muaj sia. Cov metabolism yog cov txheej txheem ntawm kev hloov cov tshuaj thiab lub zog nyob hauv ib qho muaj sia, muaj kev cuam tshuam ntau cov biomolecules thiab cov nyom biochemical. Kawm cov metabolic mechanisms tsis pub muaj cov muaj sia muaj sia muaj txiaj ntsig zoo rau kev nkag siab txog lawv lub cev muaj zog thiab cov txheej txheem ntawm cov kab mob tshwm sim.
Nws tuaj yeem cuam tshuam tus nqi thiab cov khoom lag luam ntawm cov kev tawm tsam metabolic los ntawm kev khi nrog cov roj metabolic enzymes hauv kev muaj sia. Los ntawm kev kawm nws cov txheej txheem metabolic hauv cov muaj sia, kev ua ntawm cov kev ua yeeb yam ntawm cov kab mob metabolic, substrate tshwj xeeb, thiab cov cai ntawm cov kev metabolic pathways tuaj yeem raug qhia tawm. Cov ntaub ntawv no muaj txiaj ntsig zoo rau kev nkag siab cov metabolic txheej txheem tshuaj, thiab kwv yees kev coj ua metabolic tshiab, thiab kwv yees kev coj ua metabolic ntawm cov tshuaj hauv cov tsiaj muaj sia.
Daim ntawv thov nyob rau hauv kev kawm ntawm CARDOGCOMING Transfuction
Kev hloov tes ntawm tes teeb liab yog qhov tseem ceeb ntawm kev xa cov ntaub ntawv sib kis ntawm thiab tsis pub dhau cov kab mob hlwb, cuam tshuam nrog ntau yam biomolecules thiab cov nyom biochemical. Nws tseem muaj cov ntawv thov tseem ceeb hauv kev kawm ntawm tes teeb liab.
4-Chloro-7-Azaindole tuaj yeem cuam tshuam cov kev ua si ntawm kev piav qhia txoj hauv kev los ntawm kev sib khi rau cov kab mob molecules. Los ntawm kev kawm nws cov kev ua hauv kev hloov teeb liab, cov kev cai ntawm cov teeb liab kev hloov chaw hauv kev hloov chaw nyob hauv cov kab mob tuaj yeem raug qhia tawm. Cov ntaub ntawv no yog ntawm cov nqi zoo rau kev nkag siab txog cov teeb meem transduction ib txwm muaj, thiab kwv yees cov teeb liab kev hloov pauv ntawm cov tshuaj hauv cov tsiaj muaj sia.
Hauv Tshuaj Ntsuam Xyuas Tshuaj Lom
4-chloro-7-azaindoleyog cov organic compound nrog ntau yam kev ua si. Vim nws cov qauv tshuaj tshwj xeeb, nws tau siv dav hauv ntau thaj teb.
1. Cov organic chemistry:
Hauv thaj chaw ntawm cov organic chemistry, nws yog dav siv los ua ke ntau yam organic sib sau. Nws ua haujlwm raws li cov hluavtaws thaiv thiab kev sojntsuam rau kev kawm cov tshuaj kho organic, cov qauv molecular, thiab cov khoom siv. Piv txwv li, ntau hom nitrogen heterocclic compounds, thiab nitro tebchaw, thiab nitro compounds tuaj yeem siv tau siv 4-chloro-7 azaindole ua cov khoom siv raw, uas tuaj yeem siv rau kev tshawb fawb ntxiv thiab kev txhim kho.
2. Tshuaj Kev Tsim Tshuaj:
Nws tseem dav siv nyob rau hauv kev txhim kho kev siv tshuaj. Nws pab ua ib qho tseem ceeb hauv nruab nrab lossis cov khoom siv roj hmab rau cov tshuaj siv qog, thiab kev pabcuam tshuaj tiv thaiv thiab kev tshawb fawb ntawm cov tshuaj tshiab. Nyob rau tib lub sijhawm, nws kuj tseem siv tau los kawm cov qauv thiab kev ua haujlwm ntawm cov cuab yeej muaj roj ntsha, muab cov cuab yeej tseem ceeb rau kev nkag siab cov txheej txheem ntawm lub neej thiab kab mob kab mob. Ntau hom tshuaj intermediates thiab tus neeg sib tw tshuaj molecules tuaj yeem ua ke siv 4-chloro-7 azaindole ua cov khoom siv tseem ceeb rau kev tshawb pom thiab kev nthuav dav ntawm cov tshuaj tshiab.
3. Teb ntawm cov ntaub ntawv kev tshawb fawb:
Hauv kev tshawb fawb ntawm cov ntaub ntawv kev tshawb fawb, nws tseem siv rau kev tshawb fawb thiab ua cov ntaub ntawv polymer thiab nanomaterials. Raws li cov khoom siv raw rau cov khoom siv hluav taws xob xws li roj hmab hluavtaws, cov yas, thiab txheej txheem, nws tuaj yeem txhim kho kev ua tau zoo thiab ruaj khov ntawm cov ntaub ntawv no. Nyob rau tib lub sijhawm, nws kuj tseem siv tau los ua ke cov ntaub ntawv fluorescent thiab cov ntaub ntawv tshiab rau kev tshawb fawb hauv cov khoom siv Optoelectronic thiab Optoelectronic hloov dua siab tshiab. Ntau hom khoom siv molecules thiab polymer molecules tuaj yeem ua ke siv 4-chloro-7 azaindole ua cov khoom siv tseem ceeb rau kev kawm cov qauv thiab cov khoom siv.
4. Biochemical teb:
Hauv kev ua teb ntawm biochemistry, nws tseem siv los kawm thiab txheeb xyuas cov qauv thiab kev ua haujlwm ntawm ntau cov lwg roj ntsha molecules. Nws tuaj yeem siv tau los synthesize bioactive me me molecule sib txuas thiab kev ua cov cuab yeej tseem ceeb rau kev kawm cov kev sib cuam tshuam thiab kev tswj hwm ntawm macromolecules. Piv txwv li, ntau hom kev ua haujlwm txheeb xws thiab inhibitor molecules tuaj yeem ua ke siv 4-chloro-7 Azaindole ua cov protein ntau li cov protein, nucleic adduction.
Ib txoj kev rau npaj4-chloro-7-azaindoleHauv chav kuaj:
Firstly, raw cov ntaub ntawv xws li 7-azardole, oxidant, sodium bisulfite, phosphorus oxychloride, thiab sodium hydrocide yuav tsum tau npaj. Ntawm lawv, 7-azaindole tuaj yeem suav los yog rho tawm, thiab cov oxidants yog ib qho khoom noj tshuaj pleev xim rau oxidor
Hauv cov kauj ruam no, cov oxidant undergoes ib qho tshuaj tiv thaiv oxidation nrog 7-azaindole kom tsim 7-azaindole nitrogen oxide. Cov tshuaj tiv thaiv tshwj xeeb tshuaj yog raws li hauv qab no:
C8H5N + hno3 → C8H5Tsis muaj
Nyob rau theem no, sodium bisulfite undergoes undergoes ib qho kev tawm tsam nrog 7} Azaindole-7azaindole-7azaindole-7-sulfonic acid sodium. Cov tshuaj tiv thaiv tshwj xeeb tshuaj yog raws li hauv qab no:
C8H5Tsis • Naho3 → C8H5Tsis muaj3Na
In this step, sodium N-oxide-dihydro-7azaindole-2-sulfonate reacts with phosphorus oxychloride to generate 4-chloro-7azaindole and other byproducts. Cov tshuaj tiv thaiv tshwj xeeb tshuaj yog raws li hauv qab no:
C8H5Tsis muaj3Na + pocl3 → C8H4Cln + x
Nyob rau theem no, lwm yam los ntawm -}}}}}}}}}}} cov tshuaj tiv thaiv tau kho ntxiv los ntawm kev ntxiv sodium hydroxide. Cov tshuaj tiv thaiv tshwj xeeb tshuaj yog raws li hauv qab no:
X + naoh → y + h2O
Hauv cov kauj ruam no, cov txheej txheem organic tsim los ntawm cov tshuaj tiv thaiv tau muab tshem tawm los ntawm cov khoom lag luam evaporator 4-chloro-7azaindole tshuaj hauv caug.
Los ntawm cov kauj ruam saum toj no, siab {{{{{{}} tus nqi, thiab qis} {5-AZOindole cov chaw muag tshuaj tuaj yeem tau txais. Qhov nruab nrab no tuaj yeem siv los ua synthesize ntau cov qog, tshuaj tiv thaiv, thiab cov tshuaj tua kab mob, thiab muaj cov kev thov kev pab. Ib qho ntxiv, txoj kev npaj npaj tau yooj yim ua haujlwm, muaj kev nyab xeeb thiab txhim khu kev qha, thiab tsim nyog rau kev tsim khoom.
Cim npe nrov: 4-Chloro-7-Azaindole CASE 55052-28-3, cov neeg tsim khoom, chaw tsim khoom, Hoobkas, yuav, nqe, loj, rau muag