Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab cov chaw muag khoom ntawm 5-amino-1-naphthalenesulfonic acid CAS 84-89-9 nyob rau Suav teb. Txais tos rau kev lag luam wholesale ntau qhov zoo 5-amino-1-naphthalenesulfonic acid CAS 84-89-9 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
5-amino-1-naphthalenesulfonic acid(5 {{-}} ans), tseem hu ua Laurent cov kua qaub lossis 1-naphthylamine-5-naphthylas acid nrog cov molecular formats thiab lub cev hnyav ntawm 223.25 g / mol. Cov compound no, txheeb xyuas los ntawm tus lej lej 84-89-9, tau nce siab rau kev tshawb fawb thiab muaj cov tshuaj lom neeg vim nws cov tshuaj thiab ntau yam kev pheej hmoo. Los ntawm nws lub luag haujlwm yog kev sojntsuam fluorescent hauv Biochemistry rau nws cov nqi hluav taws xob ua cov kev sib tshuam ntawm cov kev sib tshuam ntawm cov khoom siv hluav taws xob thiab siv chemistry.
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Tshuaj Cov Qauv |
C10h9No3S |
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Muaj pes tsawg leej |
223 |
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Molecular hnyav |
223 |
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m/z |
223 (100.0%), 224 (10.8%), 225 (4.5%) |
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Kev Ntsuam Xyuas |
C, 53.80; H, 4.06; N, 6.27; O, 21.50; S, 14.36 |
Cov txheej txheem synthesis ntawm5-amino-1-naphthalenesulfonic acidfeem ntau koom nrog ntau cov kauj ruam. Cov hauv qab no yog cov txheej txheem hluavtaws:
Kauj ruam 1: Sulfonation ntawm Naphthalene
C10H 8+ h2so4 → C10H8so3H + H2O
Sulfation kev tawm tsam ntawm Naphhalene (C10H8) nrog concentrated sulfuric acid (h2so4) ntawm qhov kub tsawg. Qhov kev tawm tsam no feem ntau tau nqa tawm hauv qab txias mob los tiv thaiv qhov tshwm sim ntawm cov kev tsis txaus siab uas tau tshwm sim los ntawm kev kub siab ntau. Cov tshuaj tiv thaiv ntau tshaj plaws naphhalene sulfonic acid (C10H8so3h) thiab dej (H2O).
Kauj ruam 2: Nitrification
C10H8So3H + hno3 → C10H7NO2SO3H + H2O
Nitration cov kev tshuaj tiv thaiv ntawm naphthalene sulfonic acid (C10H8so3h) nrog nitric acid (hno3) ntawm qhov kub tsawg. Qhov tshuaj tiv thaiv no yuav tsum tswj kev pom zoo thiab cov tshuaj tiv thaiv kub ntawm nitric acid kom ntseeg tau tias nitrification tshwm sim ntawm cov chaw tshwj xeeb. Cov tshuaj tiv thaiv ua rau muaj 5-nitro-1-naphystalene sulfonic acid (C10H7NO2SOs3H) thiab dej).
Kauj ruam 3: nruab nrab ntawm thiab kev sib cais
C10H7NO2SO2 → C10H8N (mg) Yog li ntawd3+ co {}} h2o
Nitralization needralization ntawm 5-nitro-1-naphthalene sulfonic acid (C10H7NO2SOs3h) siv cov pa roj magbonate (mgco3). Thaum lub sijhawm no, magnesium carbonate reacts nrog sulfigle magnesium ntsev (c10h8n (mg) so3), thiab tso tawm cov pa roj carbon dioxide (CO2). Tom qab, cov ntsev magnesium tau sib cais los ntawm kev daws los ntawm kev lim lossis lwm txoj hauv kev.
Kauj ruam 4: Restore
C10H8N (mg) Yog li ntawd3+ Fe2Ho4 → + mgso4 {} {} h2o
Ua cov kev tawm tsam txo ntawm qhov sib cais 1 {{{{}} naphthylamine-8-sulfonate magnesium ntsev (mg) so3) thiab sulfuric acid (h25o4). Cov hmoov hlau yog siv los ua tus neeg sawv cev txo qis los txo Nitro Group (NO2) rau cov pab pawg amino (NH2), ua kom muaj zog 1-naphthylamine-5-sulfonic acid (c10h9no3s). Lub caij no, cov ntsev nyeem ntawv magnesium (MGSO4) thiab ferrous sulfate (FESO4) yog tsim los ntawm cov khoom lag luam.
Kauj ruam 5: acidification
C10h9No3S + H2So4 → C10h9No3sh2sho4
Acidify txo5-amino-1-naphthalenesulfonic acid(C10h9No3s) nrog sulfuric acid (h25o4) kom tshem tawm cov kev ua kom muaj kev cuam tshuam. Cov kauj ruam no feem ntau tsis tas yuav tsum muaj kev sib txig sib luag, tab sis ua tiav los ntawm kev sib xyaw yooj yim thiab nplawm.
Vim li cas thiaj xaiv peb
Nyob rau hauv lub ntiaj teb loj heev ntawm cov tshuaj lom neeg, peb lub tuam txhab tseem ceeb lub hom phiaj yog los muab cov neeg siv khoom tshiab, tau ua tau zoo thiab high {1}- kev ua haujlwm tshuaj. Peb paub zoo tias yog ua lag luam ua lag luam hauv kev lag luam tshuaj, peb lub luag haujlwm tseem ceeb thiab lub luag haujlwm. Peb tsis tsuas yog yuav tsum tau teeb tsa lub cim hauv kev ua lag luam, tab sis kuj tseem txhawb kev thev naus laus zis kev kawm thiab cov khoom lag luam kom zoo nkauj hauv kev lag luam.
Txhim kho cov khoom lag luam zoo thiab tsim cov khoom zoo tau zoo
Peb lub tuam txhab lub tuam txhab tau ib txwm hloov ib puag ncig lub hom phiaj tseem ceeb ntawm kev txhim kho cov khoom lag luam zoo. Peb ntseeg tias tsuas yog txhim kho cov khoom lag luam tsis tu ncua peb tuaj yeem yeej txoj kev ntseeg siab ntawm cov neeg siv khoom thiab paub ua lag luam. Txog rau qhov kawg no, peb tau coj kev ntsuas kom ntseeg tau tias cov khoom zoo tshaj plaws.
Peb tsom rau kev xaiv cov ntaub ntawv raw thiab kev tswj hwm zoo. Peb tau tsim tau ntev- kev sib koom tes thiab ruaj khov sib koom tes nrog cov ntaub ntawv uas tau ua raws li cov qauv kev yuav khoom thiab cov qauv kev lag luam. Nyob rau tib lub sijhawm, peb tau tsim txoj kev tshuaj xyuas cov khoom siv ceev, ua kev kuaj nruj thiab tshuaj ntsuam xyuas ntawm txhua lub hnab nyiaj nyoos los xyuas kom meej thiab txhim khu kev qha zoo.
Peb tsom mus rau kev tswj hwm thiab kev tswj hwm ntawm cov txheej txheem ntau lawm. Peb tau qhia cov cuab yeej siv siab tsim khoom thiab cov txheej txheem thev naus laus zis, tsim cov txheej txheem kev tswj hwm zoo, thiab ua kom txhua kauj ruam ntawm cov txheej txheem tsim khoom thiab cov tseev kom muaj. Peb kuj tseem muaj zog cob qhia cov neeg ua haujlwm thiab kev kawm, txhim kho lawv cov kev paub zoo thiab kev ua haujlwm zoo, thiab ua kom muaj kev ruaj khov thiab ua haujlwm ntawm cov txheej txheem ntau lawm.
Peb tsom rau kev kuaj cov khoom thiab ntsuas. Peb tau teeb tsa qhov chaw kuaj thiab kev tshuaj ntsuam xyuas zoo rau txhua qhov kev ntsuas thiab kev tshuaj ntsuam xyuas ntawm txhua cov khoom ruaj khov, ua kom muaj kev ruaj ntseg thiab kev ntseeg tau ntawm cov khoom lag luam zoo. Nyob rau tib lub sijhawm, peb nquag sib txuas lus nrog cov neeg siv khoom, nkag siab lawv cov kev xav tau thiab cov lus qhia, ua kom tau zoo txuas ntxiv cov khoom lag luam thiab kev ua tau zoo txuas ntxiv.
Cov Ntawv Thov
► Dyestuff Intermediate
Ib qho ntawm thawj kev lag luam kev siv ntawm 5 {{{}}! {{5-naphthalenesulfonic acid yog qhov nruab nrab hauv kev ua si ntawm azo dyes. Cov amino pab pawg reacts nrog cov ntsev diazonium los ua AZO sib txuas (-n= n-), tus qauv tseem ceeb hauv ntau cov hluavtes dyes. Cov dyes no tau ua haujlwm dav hauv textiles, ntawv, thiab tawv lag luam vim lawv cov xim muaj zog thiab ruaj khov. Cov pab pawg sulfonic acid pab tau cov xim zas dej solubility, saib xyuas nws daim ntawv thov hauv cov txheej txheem dowest.
► Fluorescent Probes hauv Biochemistry Fluence
Hauv kev tshawb fawb, 5 -}}}} ion tau tshwm sim raws li qhov muaj txiaj ntsig fluorescent sojntsuam thiab protein {5} lashtand kev sib cuam tshuam. Nws lub peev xwm los ua kom ruaj khov nrog cov hlau ions, xws li Cu (II), ua rau nws muaj txiaj ntsig hauv kev tshawb nrhiav enzymatic thiab hlau atorostasis hauv biological. Piv txwv li, 5-ards derivatives zoo li n- (2,4-diphosphoyl) -1 nm, ua kom cov roj ntsha kom pom tseeb ntawm cov hlau thiab lwm yam biomolecules.
► PROUNCUM NTXIV DERIVULLATIZENTION NEEG
5-ans kuj tseem ua haujlwm hauv cov txuj ci tseem ceeb rau kev txheeb xyuas chairal phenoxy acids penoxy acids. Los ntawm reacting nrog cov tebchaw no, 5-ans cov ntaub ntawv uas yooj yim cais thiab ntes siv chromatographic txoj kev. Daim ntawv thov no yog tshwj xeeb rau cov kev ua tshuaj tua kab ib puag ncig, qhov kev tshuaj ntsuam ntawm cov tshuaj ntsuab thiab lwm yam kuab paug chiral yog qhov tseem ceeb.
Eps enzyme kinetics thiab protein kawm
Cov khoom sib xyaw ua ke fluorescent muaj txoj kev tshawb fawb kinetics kinyme kinetics los soj ntsuam cov kev tawm tsam raug. Los ntawm kev khi rau cov hlau ions hauv enzymes, 5 -}}}} MSs tuaj yeem taug qab kev ua txhaum thiab catalytic kev ua haujlwm hauv lub sijhawm tiag tiag. Ib qho ntxiv, nws lub luag haujlwm hauv kev kawm txog cov protein-ligrand kev pom zoo rau hauv cov txheej txheem molecular lees paub, kev tshawb fawb tshuaj thiab cov txheej txheem kev tshawb fawb.
Kev Kawm Txog
► AZO Ze Ze Ntau Lawm
Ib qho ntawm cov khoom tseem ceeb tshaj plaws ntawm 5-Ans yog ib nrab nyob rau hauv synthesis ntawm Azo Dyes, uas tau siv dav hauv Textiles, ntawv, thiab cov tawv lag luam.
1) Cov Txheej Txheem Txheej txheem cej luam
Sulfonation & Nafhatalene yog thawj zaug sulfonated nrog concentrated sulfuric acid los ua ib pawg nitrated los qhia rau pawg Nitro (-NO₂).
Txo rau cov amino pab pawg: pawg Nitro yog txo rau cov amino pab pawg ({}} nh₂) siv cov neeg sawv cev catalytic lossis tshuaj lom neeg cov neeg sawv cev, yielding 5-elsing 5-eding 5-elsing 5-elsing 5-elsing 5-elsing 5-elsing 5-elsing 5-elsing 5-elsing 5-elsing 5-elsing 5-elsing 5-yield..
Couplings Cov Lus Qhia: 5 {{4 4}}}}} Cov ntsev tsis zoo nrog cov kua txiv kab ntxwv (piv txwv li}
2) Tiag {- Ntiaj Teb Kev Cuam Tshuam
Lub chaw tsim khoom lag luam loj loj hauv Is Nrias teb tau tshaj tawm txog 30% nce hauv cov txheej txheem 5 {}} tus nqi hluav taws xob, txo cov nqi hluavtaws thiab cov nqi ntau lawm. Txawm li cas los xij, cov kev sib tw nyob rau hauv kev tswj hwm txoj kev xeb ntawm sulfuric acid thiab ua kom cov neeg ua haujlwm kev nyab xeeb thaum kev tiv thaiv kub.
3) Kev txiav txim siab ib puag ncig
Kev lag luam zas xim cov ntsej muag tau los txo cov dej qias neeg los ntawm sulponic acid byproducts. Cov kws tshawb nrhiav tab tom txhim kho kaw qhov kev kaw tau ...}
► Tyrosinase inhibition
5-ANS tau tshawb los ua cov peev txheej tiv thaiv tyrosinase, ib qho enzyme koom nrog cov synthein (cuam tshuam rau daim tawv nqaij pigmentation thiab khoom noj xim av).
Kev sim nrhiav
Kev kawm 2019 xyoo 2019Bioorganic anecistryKuaj 5-ans thiab nws cov derivatives tiv thaiv mus taus tyrosinase. Cov txiaj ntsig tau pom:
5-ans inhibited tyrosinase kev ua si los ntawm 65% ntawm 100 μm.
Ib qho sulfonic Acid -}} hloov cov khoom plig ua haujlwm 82%
Kev siv tshuaj
Thaum 5 {{{-}}}} an elf yog tsis yog cov neeg sib tw tshuaj, nws tus kheej kuj tuaj yeem txhawb kev kho yeeb yaj kiab tshiab los yog ntuj txuag rau cov zaub mov.
Kev txhawj xeeb txog kev nyab xeeb
CyTotoxicity: Kev nce qib siab ntawm 5-Ans yuav ua rau cov hlwb puas.
Kev daws teeb meem solubility: tsis zoo lipophilicity txwv membrane permeability.
Kev xav yav tom ntej
► Chemistry cov thawj kauj ruam
The demand for sustainable chemical processes is driving research into greener synthesis methods for 5-ANS. Kev sib tw biocatalytic, siv cov enzymes los qhia cov pab pawg ua haujlwm, yuav txo tau cov pab pawg ua haujlwm ntawm cov neeg tawm tsam hnyav thiab txo cov khib nyiab. Ib qho ntxiv, cov kev tiv thaiv-dawb cov kev tshuaj tiv thaiv thiab lub zog hluav taws xob txuas ntxiv mus ntxiv ib puag ncig kev hneev ntawm 5-ands ntau lawm.
► Cov ntawv thov Adevoptor Advanced
Tshawb cov khoom fluorescent tau raug tshawb nrhiav hauv cov ntaub ntawv txuj ci rau kev tsim cov sensors thiab cov khoom siv kho tshiab. Piv txwv li, 5 {- -} Raws polymers tuaj yeem tshawb xyuas cov hlau hlau tuaj yeem tshawb xyuas cov kev soj ntsuam thiab kev kuaj mob ib puag ncig thiab kho mob.
Peev Muaj Peev Xwm
Thaum 5-Ans feem ntau siv hauv Dyestuff thiab kev tshawb fawb, nws cov kev sib thooj sib thooj rau cov molecules qhia tias muaj peev xwm kev txhim kho. Kev hloov kho rau Naphthalene cov tub ntxhais lossis cov pab pawg sulfonic acid tuaj yeem ua rau cov kev kho mob, tshwj xeeb hauv cov cheeb tsam zoo li cov tshuaj tiv thaiv antimricrobial lossis enzyme inibitors.
5 {{3} amino-1-naphthalenesulfoniclo acid exemplifies lub synergy ntawm chemistry thiab kev lag luam. Los ntawm zas kev tsim tawm mus rau fluorescent probes, nws versatility stems los ntawm ib tug zoo-txhais qauv txheej txheem ua rau muaj kev cuam tshuam ntau yam. Raws li Science nce qib, nws cov ntawv thov hauv Green Chemistry, Nanotechnology, thiab cov chaw khaws cia rau lub zog. Txawm li cas los xij, txoj kev tuav tswj hwm lub luag haujlwm thiab ib puag ncig kev saib xyuas kev sib tw nyob hauv txoj kev ua kom muaj kev nyab xeeb.
Los ntawm bridging kev lag luam thiab txiav - ntug kev tshawb nrhiav, illuminating txoj kev tshiab, illuminating txoj kev tshiab, illillating txoj hauv kev ua rau lub neej yav tom ntej ntau dua.
Cim npe nrov: 5-amino-1-naphthalenesulfonic acid CAS 84-89-9, chaw tsim khoom, chaw tsim khoom, chaw tsim khoom, yuav khoom, rau muag