Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm 5-sulfoisophthalic acid monosodium ntsev cas 6362-79-4 nyob Suav teb. Txais tos rau cov lag luam wholesale zoo 5-sulfoisophthalic acid monosodium ntsev cas 6362-79-4 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
5-Sulfoisophthalic acid monosodium ntsev, molecular mis C8H7NaO7S, CAS 6362-79-4, yog cov hmoov dawb ruaj khov nyob rau hauv qhov kub thiab txias. Nws dissolves nyob rau hauv dej, muaj irritant thiab corrosive zog, thiab muaj ib co teeb meem rau cov dej lub cev. Nrog nws cov khoom tshwj xeeb ionic thiab cov qauv siv ntau yam, nws tau dhau los ua cov khoom siv tseem ceeb hauv kev hloov kho cov khoom siv polymer, tshuaj synthesis, thiab cov txheej txheem ib puag ncig. Nws cov txiaj ntsig thev naus laus zis (tus nqi qis, zoo ib puag ncig tus phooj ywg) thiab kev ua tau zoo (siab hardness, muaj zog tiv thaiv huab cua) tau sib koom ua ke txhawb nqa nws daim ntawv thov sib sib zog nqus hauv cov teb ib txwm muaj thiab nthuav dav hauv thaj chaw tshiab. Nrog rau kev sib sib zog nqus ntawm ntsuab chemistry thiab cov ntsiab lus kev txhim kho kom ruaj khov, 5-SSIPA xav tias yuav dhau los ua ib qho ntawm cov ntaub ntawv tseem ceeb rau kev hloov pauv thiab kev txhim kho kev lag luam tshuaj lom neeg yav tom ntej.
|
Tshuaj Formula |
C8H5NaO7S |
|
Exact Mass |
268 |
|
Molecular Luj |
268 |
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m/z |
268 (100.0%), 269 (8.7%), 270 (4.5%), 270 (1.4%) |
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Elemental Analysis |
C, 35,83; H, 1,88; yog 8,57;. 41,76; ib. Ib., 11.96 |
5-Sulfoisophthalic acid monosodium ntsev(5-SSIPA, molecular formula C ₈ H ₅ NaO ₇ S) yog ib qho tshuaj tsw qab dicarboxylic acid derivative nrog sodium sulfonate pawg ua nws cov haujlwm tseem ceeb. Nws cov qauv molecular tshwj xeeb endows nws nrog ionic zog, ua rau nws irreplaceable nyob rau hauv teb xws li dyes, pharmaceuticals, polymer cov ntaub ntawv, thiab environmentally friendly coatings.
1. Polyester dyeing hloov kho: tawg los ntawm cov kev txwv ntawm cov tsoos dyes
Sodium isophthalice-5-sulfonate, ua tus thib peb monomer ntawm polyester fibers, qhia cov pab pawg sodium sulfonate los ntawm copolymerization los tsim cov chaw tsis zoo nyob rau hauv fiber ntau. Cov yam ntxwv no ua rau nws muaj peev xwm adsorption rau cationic dyes (xws li Disperse Red thiab Disperse Blue) los ntawm 3-5 zaug, ua kom cov dyeing qhov tob ntawm 20% -30%, thiab muaj qhov zoo dua ntxuav ceev (Ntau dua lossis sib npaug rau 4 qib) thiab lub teeb nrawm (Ntau dua lossis sib npaug li 6 qib) dua li cov pa polyester.
Piv txwv li, lub caij ntuj no khaub ncaws fabrics ua los ntawm 5-SSIPA hloov polyester muaj peev xwm ua tau siab saturation dyeing ntawm cov xim tsaus nti (xws li navy xiav thiab tsaus ntsuab), thiab tom qab 50 ntxuav, xim txawv Δ E yog tsawg dua los yog sib npaug rau 1.5, ua tau raws li cov kev cai nruj durability ntawm lub high-end khaub ncaws khw.
2. Synthesis ntawm waterborne polyester resin: lub hauv paus pob zeb ntawm environmentally friendly coatings
Cov tsoos polyester resins cia siab rau cov kuab tshuaj organic xws li toluene thiab xylene rau kev sib cais, thaum 5-SSIPA tuaj yeem ncaj qha tsim cov kab ke ruaj khov nrog dej los ntawm cov khoom ionic ntawm sodium sulfonate pawg. Cov txheej txheem synthesis tau muab faib ua ob theem:
Kev npaj cov kua qaub muaj txiaj ntsig zoo: Siv 5-SSIPA, PTA, thiab ethylene glycol (EG) ua cov khoom siv raw, condensation yog nqa tawm ntawm 220-240℃kom tau cov dej-soluble polyester resin nrog acid tus nqi (AV) ntawm 60-80 mgKOH / g;
Amine neutralization cov tshuaj tiv thaiv: triethylamine (TEA) los yog ammonia dej yog ntxiv los hloov cov pawg carboxyl rau hauv ammonium ntsev los ua nanometer lotion nrog particle loj tsawg dua 50nm. Tom qab cov tshuaj pleev xim yog coated rau ntawm cov hlau substrate, lub hardness ntawm txheej txheej tuaj yeem ncav cuag 3H (xum hardness), gloss (60℃kaum sab xis) Ntau dua lossis sib npaug li 90, thiab VOC (volatile organic compounds) cov ntsiab lus tsawg dua 50g / L, uas ua raws li European Union REACH cov cai thiab US EPA cov qauv.
3. Dej raws li polyurethane dispersion: ib tug breakthrough nyob rau hauv high hardness txheej
5-SSIPA, raws li ib tug hydrophilic saw extender, tuaj yeem hloov cov tsoos DMPA thiab txhim kho kev ruaj ntseg ntawm polyurethane dispersions. Nws mechanism ntawm kev txiav txim yog raws li nram no:
Molecular tsim optimization: Cov pab pawg sodium sulfonate nyob nruab nrab ntawm benzene rings, nrog tsawg steric hindrance thiab siab reactivity nrog isocyanates (NCO). Tus nqi tshuaj tiv thaiv yog ob zaug ntawm DMPA;
Particle loj tswj: Los ntawm kev kho qhov ntau npaum li cas ntawm 5-SSIPA (3% -8% ntawm polyol pawg), qhov loj me ntawm cov dispersion tuaj yeem tswj tau nyob rau hauv thaj tsam ntawm 80-120nm, tsim lub pob tshab lossis semi pob tshab;
Kev txhim kho kev ua tau zoo: Cov txheej txheej hardness tuaj yeem ncav cuag 4H, thiab nws qhov cuam tshuam tsis kam (50kg · cm) thiab tshuaj tiv thaiv (tiv taus rau soaking hauv 5% hydrochloric acid thiab 10% sodium hydroxide tov rau 24 teev yam tsis muaj kev hloov pauv) yog qhov zoo dua li cov kuab tshuaj raws li polyurethane.
Pharmaceutical and Pesticide Intermediates: Ib Lub Platform Synthesis rau Bioactive Molecules
1. Drug delivery system (DDS) carrier
Cov pab pawg sodium sulfonate ntawm 5-SSIPA tuaj yeem tsim cov nanocomposites nrog biomolecules xws li cov proteins thiab peptides los ntawm kev sib cuam tshuam electrostatic, ua tiav cov tshuaj xa mus. Piv txwv li:
Antitumor tshuaj cab kuj: 5-SSIPA tau copolymerized nrog chitosan los npaj nanoparticles nrog particle loj<200nm. After loading doxorubicin (DOX), the inhibition rate on breast cancer cells (MCF-7) increased by 40% compared with free drugs;
Gene therapy vector: Los ntawm kev khi cov pab pawg sodium sulfonate rau phosphate qaum ntawm DNA, ib tug ruaj khov core- plhaub qauv yog tsim, thiab transfection efficiency yog 2-3 npaug ntau dua li cov tshuaj polyethyleneimine (PEI) vectors.
2. Synthesis ntawm bioactive molecules
Lub nplhaib benzene ntawm 5-SSIPA tuaj yeem siv los ua cov khoom siv hluavtaws los qhia halogens xws li fluorine thiab chlorine los ntawm kev hloov pauv ntawm sulfonic acid pawg, lossis txuas rau cov saw ntev alkyl pawg los ntawm cov tshuaj tiv thaiv esterification los npaj cov tebchaw nrog cov dej num tshwj xeeb. Piv txwv li:
Antibacterial agent: 5-SSIPA reacted nrog cetylammonium bromide (CTAB) los npaj cov tshuaj tua kab mob surfactant, nrog qhov tsawg kawg nkaus inhibitory concentration (MIC) ntawm 16 μ g / mL tiv thaiv Staphylococcus aureus (ATCC 6538);
Cov tshuaj tiv thaiv kab mob: 5-mercapto-isophthalic acid yog npaj los ntawm kev txo cov tshuaj tiv thaiv ntawm sulfonic acid pawg, thiab thiazolidinone los tiv thaiv- cov tshuaj tiv thaiv kab mob yog txuas ntxiv ua ke. Nws cov tshuaj tiv thaiv kab mob (IC ₅₀=0.5 μ M) zoo dua rau dexamethasone (IC ₅₀=1.2 μ M).
Environmentally friendly Coatings and Food Packaging: Practitioners of Green Chemistry
1. Amine dawb dej-raws li txheej: hloov cov tshuaj hnyav raws li txheej txheem
Cov dej ib txwm siv-raws li polyester resins yuav tsum tau siv cov organic amines (xws li triethylamine) los ua kom tsis muaj carboxyl pawg, uas ua rau cov amine seem nyob rau hauv txheej thiab tso tawm cov ntxhiab tsw.5-Sulfoisophthalic acid monosodium ntsevua tiav "amination dawb" synthesis los ntawm kev ncaj qha ionization ntawm sodium sulfonate pawg:
Txheej txheem yooj yim: Omitting amine neutralization kauj ruam, txo cov tshuaj tiv thaiv lub sij hawm los ntawm 30% thiab zog noj los ntawm 20%;
Kev ua kom zoo dua qub: Cov txheej txheej dej tsis kam (tsis muaj npuas tom qab 24 teev ntawm kev tso dej) thiab huab cua tsis kam (tsis muaj hmoov tom qab 500 teev ntawm QUV nrawm nrawm) tau txhim kho zoo;
Daim ntawv thov nthuav dav: Nws tau siv dav hauv tsheb OEM xim, lub tsev sab nrauv phab ntsa txheej, thiab kev lag luam los tiv thaiv- coatings coatings, thiab nws txoj kev lag luam tau nce xyoo los ntawm xyoo.
2. Khoom noj khoom haus nplaum nplaum: FDA tau ntawv pov thawj kev nyab xeeb
Polyester resin synthesized los ntawm 5-SSIPA tau ntawv pov thawj los ntawm FDA 21 CFR 175.300 thiab tuaj yeem siv rau cov khoom ntim khoom uas tuaj yeem cuam tshuam ncaj qha rau cov zaub mov, xws li cov ntawv lo rau lub raj mis dej haus thiab cov khoom noj ceev ceev adhesives. Nws txoj kev ruaj ntseg yog los ntawm:
Tsis tshua muaj kev txav mus los: Cov pab pawg sodium sulfonate yog covalently bonded rau polyester lub ntsiab saw, thiab nyob rau hauv 40℃thiab 100% av noo tej yam kev mob, tus nqi tsiv teb tsaws yog tsawg dua 0.1mg / dm ²;
Kev kub siab tiv thaiv: iav hloov kub (Tg) ntawm 80-100 degree, muaj peev xwm tiv taus pasteurization (65 degree, 30min) thiab kub filling (85 degree) txheej txheem;
Tsis muaj tshuaj lom los ntawm - cov khoom: Tsis muaj cov khoom siv hlau hnyav (xws li cov tin compounds) yuav tsum tau ua thaum lub sij hawm tsim cov txheej txheem kom tsis txhob muaj kev pheej hmoo ntawm cov hlau hnyav.
1. Sib nqus daim kab xev nplaum: siab -cov ntaub ntawv khaws cia nruab nrab
Cov nplaum uas npaj los ntawm copolymerization ntawm 5-SSIPA thiab acrylic ester tuaj yeem siv los kho cov hmoov sib nqus ntawm cov nplaum nplaum (xws li cov ntaub ntawv thaub qab daim kab xev thiab lub suab tapes). Nws qhov zoo muaj xws li:
High bonding zog: Lub tev lub zog (180 degree) ncav cuag 5N / 25mm, uas yog 30% siab dua li cov tshuaj polyurethane nplaum;
Hnav tsis kam: Tom qab 500 lub voj voog ntawm kev sib txhuam kev sib txhuam, qhov sib nqus hmoov detachment tus nqi tsawg dua 0.5%;
Qhov kub thiab txias: tuaj yeem siv tau ntev hauv thaj tsam ntawm -40℃txog 80 degree, haum rau huab cua ib puag ncig kev xav tau.
2. Ink additives: txhim kho kev luam ntawv zoo
5-SSIPA, raws li ib tug dispersant thiab stabilizer, tuaj yeem txhim kho cov khoom rheological thiab luam ntawv hloov pauv ntawm tus number case:
Particle loj tswj: Disperse pigment hais rau<1 μ m to improve ink transparency and color saturation;
Kev tiv thaiv kev daws teeb meem: Tom qab 6 lub hlis ntawm cov kua mem cia, cov xim xim xim yog tsawg dua 5% kom tsis txhob txhaws thaum luam ntawv;
Kev ziab sai sai: Los ntawm kev siv cov dej nqus ntawm cov pab pawg sodium sulfonate, nws ua rau kom qhuav ntawm number case rau saum npoo ntawm substrate, uas ua rau 20% nce hauv kev luam ntawv ceev.
5-Sulfoisophthalic acid monosodium ntsevTxoj kev Synthesis:
Txoj Kev 1:
Cov tshuaj tiv thaiv ntawm sodium terephthalate thiab 5-nitroisobenzene (los yog 5-nitroisophthalic acid):
Txoj kev no yog ib qho ntawm ntau yam ntau yam rau kev sib txuas ntawm cov khoom. Ua ntej, sodium terephthalate yog yaj hauv dej thiab tom qab ntawd hloov mus rau nws daim ntawv acid siv 10% sulfuric acid ua catalyst. Tom ntej no, 1.2 qhov sib npaug ntawm sodium nitrite tau siv rau nitration cov tshuaj tiv thaiv los npaj 5-nitroisophthalic acid. Thaum kawg, purification thiab neutralization kho kom tau nws.
Txoj Kev 2:
Synthesis ntawm p-toluenesulfonic acid thiab carbene:
Txoj kev yog tau los ntawm tosylation ntawm terephthalic acid. Ua ntej, terephthalic acid yog yaj nyob rau hauv anhydrous methanol thiab reacted nrog toluenesulfonic acid los ua ib tug intermediate (C6H4 (CO2CH3) 2CH2SO3H2). Qhov nruab nrab yog tom qab ntawd hloov mus rau cov khoom los ntawm kev ntxiv lub hauv paus xws li sodium hydroxide lossis sodium carbonate. Thaum lub sij hawm neutralization txheej txheem, vim acidity generated, tus nqi ntawm alkali siv yog me ntsis ntau tshaj qhov theoretical tus nqi.
Txoj Kev 3:
Cov tshuaj tiv thaiv carboxylation ntawm isobutyl terephthalate:
Sib txawv ntawm Txoj Kev 1, Txoj Kev 3 yog raws li kev sib txuas ntawm terephthalic acid ester pawg es tsis yog pawg acid. Ua ntej, isobutyl terephthalate reacts nrog bromoacetic acid los tsim 123-trimethyl-1,4-dibromobenzene diacetate. Tshaj acrylic acid thiab hydroxypropanesulfonic acid tom qab ntawd rov kho dua los ntawm Reißert kom hloov mus rau nws.
Txoj Kev 4:
Cov tshuaj tiv thaiv ntawm terephthalamide thiab 2,3-dichlorobenzenesulfonic acid:
Txoj kev siv terephthalamide thiab 2,3-dichlorobenzenesulfonic acid kom hnov mob nrog ethanol kiag li ua kuab tshuaj. Cov intermediates uas tsim los ntawm cov tshuaj tiv thaiv yog raug rau huab cua los ua hlau carbonyl complexes los ntawm autoxidation. Thaum kawg, lub complex raug txo los ntawm dropwise ntxiv ntawm methylene xiav tov thiab neutralized kom cov carboxylic acid moiety yielded khoom.
Txoj Kev 5:
Cov tshuaj tiv thaiv ntawm terephthalate thiab benzoxanesulfonyl chloride:
Txoj kev no yog esterified rau tert-butyl sulfate thiab tom qab ntawd tshwm sim nrog benzoxanesulfonyl chloride hauv dichloromethane. Cov tshuaj tiv thaiv ua rau siab molecular hnyav benzoxane sulfate. Thaum kawg, los ntawm neutralization,5-Sulfoisophthalic acid monosodium ntsevyog generated.
Cim npe nrov: 5-sulfoisophthalic acid monosodium ntsev cas 6362-79-4, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom