Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom lag luam zoo tshaj plaws thiab cov neeg muag khoom ntawm Adenosine hmoov li 58-61-7 nyob hauv Suav teb. Txais tos rau kev lag luam wholesale loj zoo adenosine hmoov li 58-61-7 rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Adenosine HmoovPuas yog cov hmoov hmoov uas muaj adenosine, molecular cov kab mis c10h13n5o4, CAS 58 {}}}}}}}}}}}} Txiaj "ntawm lub zog hauv cov hlwb. Adenosine yog lub nucleoside, ib qho sib xyaw ua ke los ntawm cov c10h13n5o4, thiab nws cov tshuaj phosphate ester yog Adenosine. Adenosine ua lub luag haujlwm tseem ceeb hauv Biochemistry, suav nrog kev hloov pauv ntawm adenosine triphosphate (adp) lossis adp) lossis adp) lossis ua kom tiav adenosine Monophosphate (Cyclic Adenosine Monophosphate). D-Adenosine (Nucleosid) yog chav kawm ntawm glycoschemicalBookine molecules muaj ntawm nucleic acid pk, lub hauv paus yog purine thiab pyrimidine. Cov hauv paus suav nrog cov leeg huv (pyrimidine (pyrimidine (pyrimidine), pyrimidine), thyrimidine, paj ntaub, ribose thiab nucleic acid hauv paus yog tsim ntawm -n glycosidic bonds.
 |
|
| Tshuaj Cov Qauv | C10H13N5O4 |
| Molecular hnyav | 267.24 |
| Muaj pes tsawg leej | 267.1 |
| m/z | 267.10 (100.0%), 268.10 (10.8%), 268.09 (1.8%) |
| Kev Ntsuam Xyuas | C, 44.94; H, 4.90; N, 26.21; O, 23.95 |
| Melting taw tes | 234-236 Qib (Lit.) |
| Kub taw tes | 410.43 Qib (Kwv yees nko) |
| Ceev | 1.3382 (ntxhib kwv yees) |
| Kev Cia | 2-8 degree |
| So | Soluble me ntsis hauv dej, soluble hauv dej kub, kev ua insoluble hauv ethanol (96 ib xees) thiab hauv methylene chloride. Nws yaj nyob rau hauv dilute ntxhia ntxhia acids. |
| Puab | Crystalline hmoov |
| Xim | Xim dawb |
| Acidity Coefficient (PKA) | 3.6, 12.4 (ntawm 25 degree) |
| Refronction Index | 1.7610 (kwv yees) |
| Dej solubility | Soluble hauv dej, ammonium hydroxide thiab dimethyl sulfoxide. Insoluble hauv ethanol. |
| Rotooiness (kho qhov muag) | [] 20 / d 70 ± 3 degree, c=2% hauv 5% naoh |
| Ruaj khov | Ruaj khov. Tsis sib haum nrog cov neeg sawv cev oxidizing muaj zog. |
|
|
|
Adenosine Hmoov, raws li kev ua kom kawg purine nucleoside, yog tsim los ntawm - n9 glycosidic sib khi ntawm Adenine thiab Ribose, thiab yog dav tam sim no hauv tib neeg cov hlwb. Nws tsis yog tsuas yog cov khoom txiav txim siab ntawm ATP (Adenosine Triphosphate), tab sis kuj tseem yog tus tseem ceeb molecule rau cellular lub zog metabolism, thiab kev hloov pauv ntawm lub cev. Nrog rau hauv - qhov tob qhia ntawm cov tshuab kev ua ntawm adenosine, nws daim ntawv thov kev lag luam tau nthuav dav los ntawm kev kho zaub mov, ua kev lag luam, kev lag luam thov kev lag luam thiab ntau yam.
1. Mob plawv kev kho mob
Adenosine ua lub luag haujlwm nruab nrab hauv kev kho cov kab mob plawv los ntawm kev ua kom lub ntsej muag ua kom lub ntsej muag (A1, A2A subtypes)
Antiarrhythmic: Adenosine tuaj yeem Inhibit atriovristentricularular node lub plawv dhia ntawm cov neeg mob paroxysmal sharavlitrtricular Tachycardia (PSVT). Nws siv sij hawm cuam tshuam sai (hauv vib nas this) thiab muaj ib nrab- lub neej ntawm tsuas yog ob peb feeb, xav tau kev txhaj tshuaj sai sai. Cov ntaub ntawv kuaj mob qhia tau hais tias ib qho kev txhaj tshuaj ntawm 6MG Adenosine tuaj yeem txhim kho lub ntswg sib dhos hauv 90% ntawm PSVT cov neeg mob tsis pub dhau 1 feeb. Ib qho ntxiv, Adenosine tseem siv tau los kho supraventricular arhythmias xws li atrial fibrillation thiab atrial flutter.
Txhim kho myocardial ntshav muab cov ntshav: adenosine tuaj yeem ntsuas cov ntshav kev ntxhov siab nucardial nucardial nucardial thiab qhov hnyav ntawm myocardial ischemia. Kev tshawb fawb tau pom tias Adenosine kev ntxhov siab muaj tus mob siab thiab muaj feem ntau ntawm cov neeg mob plawv, ua rau nws tsis taus ua kom muaj kev tawm dag zog.
Anti poob siab thiab hypotension: Adenosine tuaj yeem txo cov ntshav siab los ntawm kev tswj ntshav siab, thiab siv rau cov ntshav siab los yog kev phais ntshav. Nws cov nyhuv antihyperensive yog qhov me me, zam reflex lub plawv dhia ceev nrawm, tshwj xeeb yog tsim nyog rau cov neeg mob siab rau tus mob plawv concomitant.
2. Kev tiv thaiv ntawm lub paj hlwb
Adenosine ua raws li neurotransmitter lossis modulator hauv nruab nrab lub paj hlwb, inhibiting neuronal overexcitement thiab exerting neuroprotrotecting los ntawm kev ua kom a1 receptors
Cerebral Kev Tiv Thaiv Ischemia: Adenosine tuaj yeem txo cov - Reapfusion raug mob thiab txo tus nqi ntawm cell poptoptosis. Cov kev sim tau qhia tias Adenosine Pretricate tuaj yeem txo cov qhab nia neurological Deficit tau los ntawm 40% thiab cov nas nrog Cerebral Ischemia qauv
Sawv daws mob thiab pw cov kev cai: Adenosine koom nrog kev cuam tshuam ntawm kev cuam tshuam thiab tswj cov pw tsaug zog tsim los ntawm kev ua kom A2A cov khoom plig.
Lub refreshing nyhuv ntawm caffeine yog tiav los ntawm thaiv adenosine recepors. Kev tshawb fawb tau pom tias kev nce qib theem yog txuam nrog kev ua kom tsaug zog ntau ntxiv, xws li caffeine) tuaj yeem tsim hluav taws xob ntxiv.
Neurodegenerererererare cuam tshuam: adenosine tej zaum yuav muaj cov kab mob muaj peev xwm kho tau ntawm cov kab mob neuroinelon los ntawm kev siv tus kab mob ntawm Alzheamflation, kev ntxhov siab oxidative, thiab lwm txoj hauv kev. Cov kev sim tsiaj tau qhia tias Adenosine A2A receptor antagersist tuaj yeem txhim kho kev ua haujlwm hauv Alzheimer tus qauv tus qauv nas.
3. Txhaj tshuaj thiab anti -} cov kev cai tswj
Adenosine HmoovUa kom A2A cov receptors, inhibits tso tawm ntawm cov neeg sib tham nrog tnf - thiab ip-6, thiab txo cov lus teb tsis txaus
Ntev ntev cov kab mob: Adenosine tuaj yeem siv rau kev kho mob ntawm cov mob mob ntev xws li mob ntsws rheumatoid, txo cov kab mob kab mob. Cov kev tshawb fawb soj ntsuam tau pom tias Adenosine analogs tuaj yeem txhim kho o thiab lub siab ua haujlwm hauv cov neeg mob mob rheumatoid.
Antiviral nyhuv: Adenosine tuaj yeem inhibit qhov kev ua si ntawm tus kab mob siab, thiab lwm yam hauv cov kab mob viratitis, thiab txo tus kab mob siab dua, thiab txo tus kab mob siab B
Kev tiv thaiv kab mob: Adenosine tuaj yeem txhawb t lymphocyte muaj kev sib txawv, thiab txhim kho lub cev tiv thaiv kev tiv thaiv. Adenosine tuaj yeem txhim kho cov tsos mob Alimia los ntawm kev loj hlob ntawm cov hlwb pob txha hematopoietic qia hauv cov kab mob ntshav xws li cov quav dev.
4. Kev tswj cov ntshav
Adenosine ua kom muaj cov platelet om2a receptors, inhibits platelet kev sib sau ua ke, thiab txo qhov kev pheej hmoo ntawm thrombosis
Kev tiv thaiv cov hlab plawv thiab cerebrovases thiab cov tshuaj tiv thaiv kab mob: Adenosine tuaj yeem siv rau kev tiv thaiv theem nrab ntawm myocardial infarction thiab mob stroke, txo qhov kev rov ua dua. Cov kev tshawb fawb soj ntsuam tau pom tias Adenosine analogs tuaj yeem txo qhov kev pheej hmoo ntawm kev pheej hmoo ntawm cov neeg mob myocardial rov muaj dua los ntawm 25% nyob rau hauv ib xyoos hauv myocardial infarction.
AnticoMulant nyhuv: adenosine tuaj yeem inhibit thrombin induced platelet ua hauj lwm thiab prolong trotting sijhawm. Adenosine tuaj yeem siv tau rau hauv kev phais mob ncig los txhawm rau txo cov kab mob thromomosis thiab txo qis kev sib txawv.
Kev saib xyuas kev noj qab haus huv: kev txhawb nqa kev txhawb nqa hauv cov khoom noj thiab kev ua haujlwm dej haus
1. Daim ntawv thov hauv kev lag luam khoom noj khoom haus
Cov tsw yeeb tshuaj: Adenosine koom rau hauv cov tshuaj tiv thaiv tshuaj thaum lub sij hawm fermentation lossis guanium acid thiab guanol acid thiab cov khoom siv rau kev npaj ntawm cov condiments thiab essence. Piv txwv li, hauv kua ntses brewing, adenosine tuaj yeem txhim kho Umami siv thiab txhim kho saj.
Cov khoom noj muaj txiaj ntsig: Adenosine, raws li lub nucleoside cov khoom, muab lub zog metabolism txhawb hauv kev haus dej haus hauv kev ua haujlwm lossis tshuaj noj qab haus huv. Piv txwv li, tus nqi pom zoo rau cov mis mos nyob hauv European thiab Asmeskas lub teb chaws yog 72mg / l (kwv yees li 111cal), thiab Adenosine tuaj yeem hloov kho raws tus qauv no. Tsis tas li ntawd, Adenosine tseem siv tau los ua cov kev ua si ncaws pob ntxiv los txhim kho kev ua kom muaj kev tawm dag zog.
2. Kev Ua Haujlwm Hauv Kev Noj Qab Haus Huv thiab Cov Khoom Noj Qab Haus Huv
Kev Txhawb Zog Kev Txhawb: Adenosine koom nrog ATP synthesis, muab lub zog rau cov hlwb tom qab kev tawm dag zog lossis hauv lub xeev nkees. Adenosine feem ntau ntxiv rau cov dej qab zib hauv khw hauv kev ua lag luam kom txhim kho lawv cov nyhuv kom rov zoo. Piv txwv li, qee hom kev haus dej haus uas muaj 50mg / fwj ntawm adenosine tuaj yeem txhim kho cov leeg nqaij glycogen rov qab tom qab tawm dag zog.
Kev tiv thaiv kab mob: Adenosine tau txhim kho lub cev tiv thaiv los ntawm kev sib txawv ntawm kev tiv thaiv kab mob thiab muaj kev tiv thaiv kab mob, ua rau cov neeg uas tsis muaj zog tiv thaiv cov neeg. Cov kev tshawb fawb soj ntsuam tau pom tias kev txhawb nqa txhua hnub ntawm 200mg adenosine rau 3 lub hlis tuaj yeem txhim kho cov neeg laus hauv cov neeg laus.
Anti Latasge nyhuv: Adenosine tuaj yeem txhim kho lub cev muaj peev xwm tiv taus kev ntxhov siab thiab kev tawm dag zog lossis ua haujlwm. Cov kev sim tsiaj tau qhia tias Adenosine tuaj yeem ua kom lub sijhawm ua luam dej lub sijhawm ntawm nas thiab txo cov ntshav lactate.
1. Kev Siv Khoom Siv
Cov kuab tshuaj thiab kev txhawb nqa catalyst:Adenosine Hmoovtuaj yeem ua haujlwm raws li kev pab kom pab yaj thiab tawg lwm cov tshuaj, lossis ua kev txhawb nqa catalyst los txhim kho kev tawm tsam efficiency. Piv txwv li, hauv cov synthic synthesis, tus nqi ntawm Adenosine ntxiv ntxiv rau 1% (cov nyiaj uas xav tau raws li cov khoom lag luam.
Polymer Cov Khoom Siv Ntxiv: Adenosine tuaj yeem siv los txhim kho cov khoom siv lub cev xws li yoog raws li cov khoom siv polymer. Piv txwv li, hauv kev ua yas ua, ntxiv 0.5% -2% Adenosine tuaj yeem txhim kho cov khoom siv thiab txo cov brittleness kub.
Cov khoom siv biochemical reagent: Adenosine yog cov khoom siv tseem ceeb rau cov khoom siv biochemical xws li cyclic adenosine monophosphate (chaw pw hav zoov). Hauv ATP synthesis, tus qauv hniav nyiaj ntawm Adenosine rau Triphosphate pawg yog 1: 3, thiab cov kev tiv thaiv lub sijhawm yuav tsum tau tswj tsis pub dhau 2 teev.
2. Textile Kev Lag Luam
Zas penetrisrant: Adenosine, raws li cov neeg sawv cev ntawm tus neeg sawv cev rau tusyees thiab txhim kho Dob ntawm kev sib dhos. Nws cov kev xav tau yog 0.5% -2% (rau ntaub zoo). Piv txwv li, hauv paj ntaub ntaub nplawm, ntxiv 1% adenosine tuaj yeem ua kom cov xim nrawm los ntawm ib theem.
Fiber hloov hloov kho: Adenosine tuaj yeem hloov cov khoom saum npoo ntawm cov fibers los ntawm cov fibers los ntawm cov tshuaj lom neeg mob siab nrog lawv, xws li txhim kho anti {{} cov khoom siv thiab kev muag khoom. Piv txwv li, hauv tus ncej -}}}} Cov ntaub ntawv anti {} thiab txo cov kev sib txhuam voltage los ntawm 50%.
Cov tshuaj pleev ib ce: Ntau cov khoom xyaw ua haujlwm rau anti -}} kev laus thiab tawv nqaij txias
1. Anti Laus effect
Daim tawv nqaij txuag: Adenosine, raws li anti - Tus neeg sawv cev ntawm lub zog, txhawb nqa daim tawv nqaij cell metabism, thiab tiv thaiv kev tiv thaiv daim tawv nqaij so. Cov chaw sim kho mob tau pom tias tom qab 8 lub lis piam ntawm kev txuas ntxiv ntawm cov tawv nqaij tawv
Daim tawv rov qab kho tawv: Adenosine tuaj yeem rov kho cov qauv tawv nqaij thiab rov ua daim tawv nqaij elasticity los ntawm zawm thiab shrinking pores. Adenosine tau hais meej meej raws li kev tawm tsam wrinkle muaj cov khoom xyaw ua tshuaj pleev li Kauslim cov tshuaj pleev ib ce ACTMETS ACT.
2. Moisturizing thiab antioxidant thaj chaw
Cov neeg muaj dej num muaj zog: Adenosine tuaj yeem nqus thiab xauv rau hauv noo noo, ua kom tawv nqaij noo noo cov ntsiab lus. Cov kev sim qhia tau pom tias lub ntsej muag cream muaj 1% adenosine tuaj yeem nce cov nqaij cov dej los ntawm 25%, thiab cov nyhuv noo nyob ntev dua 8 teev.
Antioxidants: Adenosine tuaj yeem Screemenge Dawb radicals thiab zam oxidative oxidative puas los ntawm ultraviolet hluav taws xob. Adenosine tuaj yeem syergine nrog lwm cov antioxidant Cheebtsam hauv cov khoom tiv thaiv tsom rau cov teebmeem kev tiv thaiv. Nyob rau hauv cov kev sim vito tau qhia tias Adenosine muaj 60% kev coj ua tus nqi ntawm superoxide anion radicals.
3. Anti mob qog thiab tshuaj tua kabmob
Anti inflammatory effect: Adenosine tuaj yeem inhibit tawm ntawm cov neeg kho mob uas ua rau cov nqaij liab, thiab khaus, thiab haum rau kev saib xyuas cov tawv nqaij rhiab. Cov kev tshawb fawb soj ntsuam tau qhia tias cov khoom lag luam me nyuam yaus tuaj yeem txo cov qhab nia tshwm sim los ntawm 40% hauv cov neeg mob uas rhiab.
Cov nyhuv tiv thaiv kab mob: Adenosine tuaj yeem cuam tshuam nrog tus tsov ntxhuav acid synthesis thiab muaj pob txig ua rau cov kab mob, ua kom haum rau siv hauv pob txuv. Hauv cov kev sim vitro pom tias qhov tsawg tshaj plaws inhibitions cov adenosine tiv thaiv propionibacterium acnes yog 0.5mg / ml.
Cov synthesis ntawmAdenosine HmoovFeem ntau cuam tshuam nrog ntau cov kauj ruam, suav nrog de Novo synthesis ntawm nucleotides thiab khaws cia txoj hauv kev. Txawm li cas los xij, cov txheej txheem hluav taws xob tshwj xeeb yuav sib txawv ntawm kev lag luam nyob ntawm kev tsim khoom.
Nyob rau hauv dav dav, adenosine synthesis cuam tshuam nrog txuas ntawm ribose, phosphate thiab adenine bases.
(1) phosphorherlation ntawm ribose
Ua ntej, Ribose (feem ntau d - pibose) yog phosphorylated rau daim ntawv ribose rau hauv lub xub ntiag ntawm Kinase.
(2) Txuas ntawm cov hauv paus los txhawm rau qhwv
Adenine Bases yog txuas rau ribose ntsev los ntawm cov enzymes tshwj xeeb (piv txwv li adenyylate synthe) los ua adenylate (amp).
(3) Ntxiv rau phosphorylation
Adenosine Monophosphate (AMP) tuaj yeem txuas ntxiv rau Adenosine diphosphate (ADP) los ntawm kev ntsuas ntxiv nyob rau hauv lub xub ntiag ntawm adenylate kinase.
Txawm li cas los xij, qhov no yog qhov kev qhia yooj yim heev thiab cov txheej txheem hluavtaws tseeb yuav suav nrog cov kauj ruam nruab nrab ntau ntxiv thiab cov enzymes.
Raws li rau cov tshuaj tiv thaiv tshuaj tshwj xeeb cov tshuaj lom neeg, nws yog qhov nyuaj los qhia ib qho tshuaj tiv thaiv ib zaug vim muaj cov txheej txheem saftthesis yog cov kauj ruam. Tsis tas li ntawd, cov qauv hluavtaws siv hauv kev lag luam yuav sib txawv nyob ntawm cov khoom lag luam thiab cov khoom lag luam.
Cim npe nrov: Adenosine Hmoov Lis 58-61-7, Tus neeg muab khoom, chaw tsim khoom, Hoobkas, lag luam Wholesale, yuav, nqe, loj, rau muag