Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm methyl 4-bromo-2-fluorobenzoate cas 179232-29-2 nyob rau hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo methyl 4-bromo-2-fluorobenzoate cas 179232-29-2 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Tom ntej: Methyl 4-bromo-2-fluorobenzoateyog ib qho tshwj xeeb organic compound teej tug mus rau cov chav kawm ntawm aromatic esters. Nrog rau cov qauv molecular ntawm C8H6BrFO2, qhov sib xyaw no muaj qhov sib xyaw ua ke ntawm bromine (Br), fluorine (F), thiab ester functionalities, imparting nws nrog cov tshuaj sib txawv thiab kev siv.
Raws li kev tsim qauv, nws muaj cov pob txha benzoate ester qhov twg pawg carboxyl (-COOH) ntawm 4-bromo-2-fluorobenzoic acid tau hloov los ntawm pawg methoxy (-OCH3). Lub nplhaib uas muaj ntxhiab muaj bromine atom ntawm para txoj hauj lwm (4-txoj hauj lwm) thiab fluorine atom ntawm ortho txoj hauj lwm (2-txoj hauj lwm) txheeb ze rau ester linkage. Qhov kev npaj no cuam tshuam nws lub cev, xws li solubility thiab melting point, nrog rau nws cov reactivity.
Cov compound feem ntau yog cov xim tsis muaj xim rau daj daj daj lossis cov khoom, nyob ntawm cov xwm txheej, nrog cov ntxhiab tsw txawv ntawm cov tshuaj tsw qab esters. Nws solubility profile txawv, ua ntau soluble nyob rau hauv cov organic solvents xws li ethanol, acetone, thiab dichloromethane dua nyob rau hauv dej. Lub melting point feem ntau nyob nruab nrab ntawm 40-45 degree, txawm hais tias qhov no tuaj yeem sib txawv me ntsis raws li purity thiab crystallization tej yam kev mob.Chemically, tus ester no kuj ruaj khov nyob rau hauv ambient tej yam kev mob tab sis muaj peev xwm mus dhau ntau yam organic transformations vim muaj cov bromine thiab fluorine substituents. Cov no suav nrog nucleophilic aromatic hloov cov tshuaj tiv thaiv, kev sib txuas sib txuas, thiab ester hydrolysis, thiab lwm yam. Cov tshuaj tiv thaiv no muaj ntau txoj hauv kev siv hluavtaws rau kev npaj cov derivatives nrog cov khoom tsim nyog rau cov ntawv thov tshwj xeeb.
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Tshuaj Formula |
C8H6BrFO2 |
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Exact Mass |
231.95 |
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Molecular Luj |
233.04 |
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m/z |
231.95 (100.0%), 233.95 (97.3%), 232.96 (8.7%), 234.95 (8.4%) |
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Elemental Analysis |
C, 41,23; H, 2,60; Saib, 34,29; F, 8.15; 13.73 Nws |
Methyl 2-fluoro-4-bromobenzoate tuaj yeem siv los ua cov tshuaj nruab nrab los koom nrog hauv kev sib txuas ntawm ntau yam tshuaj nrog kev tiv thaiv kab mob, tshuaj tua kab mob, thiab tiv thaiv qog nqaij hlav. Qee cov tshuaj uas muaj cov qauv ntawm methyl 2-fluoro-4-bromobenzoate tau siv los kho mob qog noj ntshav, kab mob thiab lwm yam kab mob. Tsis tas li ntawd, methyl 2-fluoro-4-bromobenzoate kuj tseem siv tau los ua cov neeg nqa tshuaj los txhim kho cov solubility thiab bioavailability ntawm cov tshuaj. Hauv thaj teb ntawm cov tshuaj tua kab, qhov sib xyaw no tseem qhia tau tias muaj peev xwm loj thiab muaj zog tua kab mob thiab kab mob.
Nws tuaj yeem siv los ua cov khoom muaj nyob hauv cov tshuaj tua kab xws li tshuaj tua kab thiab fungicides los tiv thaiv thiab tswj cov kab mob qoob loo thiab kab tsuag.Qhov tseem ceeb tshaj plaws yog qhov sib xyaw no tsis tshua muaj kev cuam tshuam rau ib puag ncig thiab kab mob. Raws li ib qho tseem ceeb organic compound, methyl 2-fluoro-4-bromobenzoate yog dav siv. Nws tuaj yeem siv los ua tus thawj coj ntawm cov khoom siv hluavtaws los koom nrog hauv kev npaj ntau yam khoom siv nrog cov haujlwm tshwj xeeb thiab cov khoom. Piv txwv li, nws tuaj yeem siv los ua ib feem ntawm cov khoom siv optoelectronic los npaj cov khoom siv xws li hnub ci hlwb thiab lub teeb emitting diodes.
Kev siv tshuaj
Kev siv ntawmTom ntej: methyl 4-bromo-2-fluorobenzoateraws li qhov nruab nrab ntawm cov tshuaj synthesis tso cai rau kev tsim cov tshuaj kho tshiab nrog cov txiaj ntsig zoo dua li kev kho mob uas twb muaj lawm. Cov neeg ua haujlwm no tuaj yeem ua kom pom qhov ua tau zoo dua qub, txo cov tshuaj lom, lossis cov txheej txheem tshiab ntawm kev ua haujlwm, pab txhawb kev nce qib hauv kev kho mob.
Hom phiaj -Kev hloov kho tshwj xeeb: Cov bromine thiab fluorine atoms tuaj yeem siv los ua haujlwm rau kev hloov kho tshuaj ntxiv, ua kom muaj kev sib txuas ntawm cov tshuaj uas tshwj xeeb cuam tshuam nrog cov hom phiaj lom neeg xws li enzymes, receptors, lossis ion channels.
Txhim kho Bioavailability thiab Metabolism: Cov pab pawg ester tuaj yeem ua rau metabolically cleaved nyob rau hauv vivo, tso cov aromatic moiety uas tej zaum yuav muaj cov tshuaj pharmacological. Lub halogen atoms tuaj yeem cuam tshuam rau cov tshuaj pharmacokinetic ntawm cov tshuaj, xws li nws cov solubility, nqus, thiab tshem tawm tus nqi.
Optimization ntawm Cov Neeg Siv Tshuaj: Lub peev xwm los kho cov qauv tshuaj los ntawm kev hloov kho hluavtaws tso cai rau kev tshawb nrhiav cov qauv- kev sib raug zoo. Qhov no yog qhov tseem ceeb rau kev ua kom zoo rau kev ua haujlwm lom neeg thiab txo cov kev mob tshwm sim ntawm cov neeg sib tw tshuaj.
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Tshuaj tua kab mob
Halogenated aromatic compounds feem ntau pom muaj cov kab mob tua kab mob, tshuaj tua kab mob, lossis tshuaj tiv thaiv kab mob. Kev sib xyaw ua ke rau hauv cov tshuaj tua kab mob tuaj yeem ua rau cov tshuaj tshiab nrog kev txhim kho tshwj xeeb thiab kev ua tau zoo. Tshwj xeeb, bromine thiab fluorine atoms hauv Methyl 4-bromo-2-fluorobenzoate tuaj yeem kho lipophilicity thiab electron ceev ntawm cov qauv molecular, pab cov tshuaj zoo dua nkag mus rau cov kab mob cell membranes thiab khi rau lub hom phiaj enzymes, yog li txhim kho cov kab mob thiab txo cov tshuaj tiv thaiv.
Oncology
Fluorinated aromatic rings muaj nyob rau hauv ntau cov tshuaj tiv thaiv kab mob vim lawv muaj peev xwm cuam tshuam nrog DNA los yog cuam tshuam rau cov kev taw qhia txoj hauv kev koom nrog hauv kev loj hlob ntawm tes. Lub bromine atom tuaj yeem muab cov ntsiab lus ntxiv rau kev cuam tshuam nrog cov hom phiaj lom neeg. Raws li fluorinated thiab brominated aromatic ester, Methyl 4-bromo-2-fluorobenzoate tuaj yeem ua haujlwm tseem ceeb hauv cov tshuaj tiv thaiv kab mob sib txuas, qhov twg fluorine atom stabilizes cov qauv molecular thiab txhim kho nws txoj kev sib raug zoo rau cov kab mob qog noj ntshav tshwj xeeb receptors, thaum lub sij hawm kho kom zoo dua bromine atom. kev ua tau zoo.
Neuropharmacology
Cov tshuaj tsom rau lub hauv paus paj hlwb feem ntau tau txais txiaj ntsig los ntawm halogen hloov pauv mus rau kev hloov pauv affinity, selectivity, thiab pharmacodynamics. Nws tuaj yeem yog qhov pib ntawm kev tsim cov tshuaj tiv thaiv neuroactive tshiab. Cov halogen hloov pauv hauv Methyl 4-bromo-2-fluorobenzoate tuaj yeem tswj cov tshuaj solubility hauv lipid daim nyias nyias ntawm cov paj hlwb, txhim kho nws cov ntshav-hlwb thaiv kev nkag mus, thiab kho kom zoo nws cov peev xwm khi rau hauv nruab nrab paj hlwb receptors, nteg ib lub hauv paus tshiab rau kev tsim tshuaj.
Hauv cov ntsiab lus, halogenated aromatic nplhaib thiab ester pawg ua rau nws muaj ntau yam nruab nrab hauv kev lag luam tshuaj. Nws kev koom ua ke rau hauv txoj kev siv tshuaj sib txuas tuaj yeem ua rau muaj kev txhim kho cov tshuaj kho tshiab uas tsom rau txoj hauv kev lom neeg tshwj xeeb, yog li ua rau muaj kev nce qib tseem ceeb hauv kev kho mob.
nyob rau hauv cov ntaub ntawv organic optoelectronic
Organic Solar Cells
Electron-Accepting Properties
Hauv cov organic solar cells, nws tuaj yeem ua raws li cov khoom siv hluav taws xob txais. Nws lub nplhaib halogenated aromatic tuaj yeem pab txhawb kev sib cais thiab thauj, uas yog qhov tseem ceeb rau kev ua haujlwm zoo photovoltaic.
Lub zog qib sib piv
Lub zog theem ntawm qhov siab tshaj plaws nyob hauv molecular orbital (HOMO) thiab qis tshaj plaws uas tsis muaj nyob hauv molecular orbital (LUMO) ntawm qhov sib xyaw no tuaj yeem hloov kho kom haum rau cov khoom siv hluav taws xob- pub dawb, txhim kho cov nqi hloov pauv thiab txo cov kev poob rov qab.
Morphological tswj
Kev koom ua ke ntawm halogen atoms tuaj yeem cuam tshuam rau tus kheej - kev sib dhos thiab cov khoom siv morphological ntawm cov txheej txheem hauv lub hnub ci, uas yog qhov tseem ceeb rau kev txhim kho kev thauj mus los thiab kev nqus lub teeb.
Lub teeb -Emitting Diodes (LEDs)
Emitter los yog Host Material
Nws tuaj yeem siv los ua tus emitter lossis cov khoom siv hauv OLEDs. Nws lub peev xwm los cuam tshuam nrog lub teeb tuaj yeem ua rau muaj txiaj ntsig luminescence, ua rau nws tsim nyog rau kev siv hauv cov lus qhia thiab teeb pom kev zoo.
Hloov zog
Qhov sib xyaw ua ke tuaj yeem pab txhawb cov txheej txheem hloov hluav taws xob hauv OLED, txhim kho kev ua haujlwm thiab xim purity ntawm lub teeb tawm.
Thermal thiab Chemical Stability
Lub nplhaib halogenated aromatic thiab ester pab pawg tuaj yeem ua rau lub thermal thiab tshuaj ruaj khov ntawm cov khoom siv LED, ua kom ntev - lub sijhawm ua haujlwm ruaj khov thiab ua haujlwm tau zoo.
Lwm yam khoom siv Optoelectronic
Photodetectors
Lub compound lub rhiab heev rau lub teeb yuav harnessed nyob rau hauv photodetectors, enabling hloov dua siab tshiab ntawm optical signals rau hauv hluav taws xob signals nrog siab rhiab heev thiab ceev.
Organic Field-Cov nyhuv Transistors (OFETs)
Nws tuaj yeem ua tus semiconductor lossis them nqi thauj khoom hauv OFETs, cuam tshuam rau kev them nqi mus thiab kev ua haujlwm ntawm cov cuab yeej.
Sensors
Qhov tshwj xeeb optoelectronic cov khoom ntawm cov khoom sib xyaw no tuaj yeem siv rau hauv cov sensors txhawm rau txheeb xyuas ntau yam kev ntsuas, xws li cov pa roj, vapors, lossis cov roj ntsha molecules.
Lub peev xwm ntawmTom ntej: methyl 4-bromo-2-fluorobenzoatelos cuam tshuam nrog lub teeb thiab hluav taws xob stems los ntawm nws cov qauv molecular thiab cov khoom hluav taws xob. Lub nplhaib halogenated aromatic thiab ester pawg pab txhawb rau nws qhov nqus thiab emission yam ntxwv, ua rau nws muaj txiaj ntsig zoo hauv cov khoom siv optoelectronic.
Tom ntej: Methyl 4-bromo-2-fluorobenzoate, ntau yam organic compound nrog cov tshuaj formula C8H6BrFO2, nthuav tawm cov khoom siv hluav taws xob zoo nkauj uas ua rau nws tseem ceeb hauv ntau yam kev siv hauv thaj chaw ntawm optoelectronics thiab cov khoom siv science. Qhov no aromatic ester sib xyaw ua ke cov yam ntxwv tshwj xeeb ntawm bromine thiab fluorine hloov pauv, uas cuam tshuam rau nws cov cwj pwm hluav taws xob thiab kho qhov muag.
Hais txog cov khoom siv hluav taws xob, kev taw qhia ntawm bromine atom ntawm 4-txoj hauj lwm thiab fluorine atom ntawm 2-txoj hauj lwm ntawm lub nplhaib benzoate hloov cov qib molecular zog thiab hluav taws xob faib. Cov kev hloov pauv no ua rau muaj kev hloov pauv ntawm HOMO (Highest Occupied Molecular Orbital) thiab LUMO (Lowest Unoccupied Molecular Orbital) lub zog sib txawv, cuam tshuam rau cov khoom siv hluav taws xob conductivity thiab them cov cab kuj.
Tshwj xeeb, qhov hloov pauv fluorine nyiam tshem tawm cov khoom siv hluav taws xob, thaum bromine ua raws li cov khoom siv hluav taws xob me me, tsim kom muaj lub cev polarized uas tsim nyog rau kev sib cuam tshuam hauv hluav taws xob.
Optically, nws qhia txawv qhov nqus thiab emission yam ntxwv nyob rau hauv lub ultraviolet rau pom lub teeb cheeb tsam. Lub xub ntiag ntawm halogen atoms, tshwj xeeb tshaj yog bromine thiab fluorine, feem ntau ua rau kom muaj zog nqus bands vim muaj zog molecular polarizability. Qhov sib xyaw no tuaj yeem hloov pauv ntawm cov hluav taws xob sib txawv thaum lub teeb haum, ua rau nws muaj peev xwm sib tw siv rau hauv cov ntaub ntawv luminescent lossis ua chromophore hauv dyes thiab pigments.
Tsis tas li ntawd, nws cov lus teb photoelectric, suav nrog photoconductivity thiab photosensitivity, yog qhov tsim nyog. Thaum raug lub teeb, nws tuaj yeem pom cov kev hloov hauv nws cov hluav taws xob conductivity, ua rau nws tsim nyog rau kev siv hauv photoconductive keyboards, lub teeb sensors, thiab cov khoom siv photovoltaic. Kev sib xyaw ntawm cov khoom no qhia tias nws muaj peev xwm siv tau los tsim cov khoom siv optoelectronic tshiab uas siv nws cov yam ntxwv photoelectric tshwj xeeb rau kev ua haujlwm siab heev.
kev phiv tshuaj
Methyl 4-bromo-2-fluorobenzoate (CAS naj npawb: 179232-29-2) yog ib qho tshuaj tsw qab ester uas muaj bromine thiab fluorine hloov pauv. Vim nws cov qauv tshuaj tshwj xeeb, nws tau siv dav hauv kev lag luam tshuaj intermediates, tshuaj tua kab synthesis, thiab cov ntaub ntawv organic. Txawm li cas los xij, kev sib koom ua ke ntawm bromine atoms (cov pab pawg muaj zog electron tshem tawm) thiab fluorine atoms (cov ntsiab lus electronegative heev) hauv nws cov molecule yuav ua rau muaj ntau yam tsis zoo.
Daim tawv nqaij tiv thaiv kev phiv
Stimulating teb
Raws li SDS luam tawm los ntawm Apollo Scientific, Methyl 4-bromo-2-fluorobenzoate tau qhia meej meej raws li cov tawv nqaij khaus (Skin Irritant 2, H315), thiab nws cov txheej txheem teeb meem suav nrog:
Kev khaus khaus: Tsis pub dhau ob peb feeb ntawm kev sib cuag, daim tawv nqaij yuav hnov qhov liab, o, kub hnyiab lossis stinging. Tsiaj thwmsim tau pom tias tom qab kis tau ntawm daim tawv nqaij luav mus rau 5% concentration ntawm cov tshuaj tov, me me mus rau nruab nrab erythema tshwm sim nyob rau hauv 24 teev, nrog rau qee qhov chaw nrog epidermal shedding.
Cov teebmeem tshwm sim ntev: Lub sijhawm ntev lossis rov raug dua (xws li tsis hnav cov hnab looj tes tiv thaiv hauv kev lag luam) tuaj yeem ua rau tawv nqaij qhuav, flaky, tawg, thiab txawm tias kis kab mob thib ob. Ib txoj kev tshawb nrhiav kev tsom mus rau cov kws kho mob hauv kev lag luam tshuaj pom tau tias cov neeg uas raug rau nws ntau tshaj 20 teev hauv ib lub lis piam muaj 3.2 npaug ntau dua ntawm cov tawv nqaij khaus piv rau pawg tswj hwm.
Kev ua xua
Txawm hais tias tam sim no tsis muaj pov thawj ncaj qha los qhia tias qhov sib xyaw muaj qhov ua xua (tsis suav tias yog daim tawv nqaij sensitizer), brominated aromatic compounds tuaj yeem ua rau qeeb hom hypersensitivity tshua (hom IV) los ntawm covalently khi rau ntawm daim tawv nqaij proteins. Piv txwv li, methyl bromobenzoate tebchaw tau pom nyob rau hauv cov tsiaj sim ua rau kev sib cuag dermatitis thaum raug rov tshwm sim, qhia tias Methyl 4-bromo-2-fluorobenzoate yuav ua rau muaj kev pheej hmoo zoo sib xws. Nws raug pom zoo tias cov neeg uas nkag siab zoo rau halogenated aromatic tebchaw tsis txhob sib cuag ncaj qha.
Kev pheej hmoo nkag
Cov khoom xyaw muaj qhov hnyav me me (233.03 g / mol) thiab muaj cov roj soluble fluorine atoms, uas tuaj yeem nkag mus rau cov hlab ntsha los ntawm daim tawv nqaij. Txawm hais tias tam sim no tsis muaj cov ntaub ntawv nqus ntawm tib neeg, kev sim tsiaj tau pom tias tom qab siv koob tshuaj 100 mg / kg rau ntawm daim tawv nqaij ntawm nas, metabolites tau kuaj pom hauv cov zis hauv 24 teev, qhia tias muaj kev pheej hmoo kis mob.
Cim npe nrov: methyl 4-bromo-2-fluorobenzoate cas 179232-29-2, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom