Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm feem kev paub manufacturers thiab lwm tus neeg ntawm th (4-10) nyob rau hauv Suav teb. Txais tos rau cov lag luam wholesale bulk siab zoo acth (4-10) muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
ACTH (4-10)yog lub ntsiab active heptapeptide fragment ntawm N-terminus ntawm tib neeg adrenocorticotropic hormone (ACTH 1-39), muaj li ntawm xya amino acids xws li methionine thiab glutamic acid. Kuj hu ua adrenocorticotropic hormone active heptapeptide, nws muaj CAS naj npawb ntawm 17988-37-5. Qhov txawv ntawm nws cov qauv compact thiab kev ua haujlwm zoo, nws txawv ntawm qhov ntev ACTH nyob rau hauv nws txoj kev tswj dav dav thiab es tsis txhob tsom mus rau cov teebmeem tshwj xeeb.
Peb cov khoom Form
ACTH (4-10) COA
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| Certificate of Analysis | ||
| Compound npe | ACTH (4-10) | |
| Qib | Pharmaceutical qib | |
| CAS Nr. | 4037-01-8 | |
| Ntau | 46g | |
| Ntim txheem | PE hnab + Al foil hnab | |
| Chaw tsim tshuaj paus | Shaanxi BLOOM TECH Co., Ltd | |
| Ntau No. | 202601090056 | |
| MFG | Peb 9, 2026 | |
| EXP | Peb 8, 2029 | |
| Qauv |
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| Yam khoom | Enterprise txheem | Kev txheeb xyuas qhov tshwm sim |
| Qhov tshwm sim | Dawb los yog yuav luag dawb hmoov | Ua raws |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 5.0% | 0.96% |
| Poob rau ziab | Tsawg dua lossis sib npaug li 1.0% | 0.32% |
| Hnyav Hlau | Pb Tsawg dua lossis sib npaug li 0.5ppm | N.D. |
| Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Hg Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Cd Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Purity (HPLC) | Ntau dua lossis sib npaug li 99.0% | 99.90% |
| Ib leeg impurity | <0.8% | 0.42% |
| Tag nrho microbial suav | Tsawg dua lossis sib npaug li 750cfu / g | 105 |
| E. Coli | Tsawg dua lossis sib npaug li 2MPN / g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (los ntawm GC) | Tsawg dua lossis sib npaug li 5000ppm | 5 16 ppm |
| Cia | Khaws rau hauv qhov chaw kaw, tsaus, thiab qhuav hauv qab -20 degree | |
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| Tshuaj Formula | C44H59N13O10S | |
| Exact Mass | 961.42 | |
| Molecular Luj | 962.10 | |
| m/z | 961.42(100.0%), 962.43(47.6%), 963.43(11.1%), 962.42(4.8%), 963.42(4.5%), 963.42(2.3%), 964.42(2.2%), 963.43(2.1%) | |
| Elemental Analysis | C,54.93; H,6.18; N,18.93; O,16.63; S,3.33 | |
Cov ntawv thov hauv Kev Tshawb Fawb Txog Kev Tshawb Fawb
Hauv kev tshawb fawb hauv paus, ACTH (4-10) tau dhau los ua cov cuab yeej tseem ceeb peptide rau kev tshawb xyuas neurophysiology, kev tswj hwm endocrine, thiab cov txheej txheem tiv thaiv kab mob vim nws cov qauv zoo, kev ua haujlwm tshwj xeeb, thiab yooj yim ntawm kev sib txuas. Nws yog dav siv hauv kev sim ntawm tes, kev tshawb fawb tsiaj txhu, thiab kev tshawb nrhiav molecular mechanism, muab kev txhawb nqa tseem ceeb rau kev tshawb fawb txog kab mob ntsig txog kab mob.
(1) Basic Neuroscience Research
ACTH (4-10) tuaj yeem hla cov ntshav-hlwb teeb meem thiab tshwj xeeb khi rau MC3R thiab MC4R hauv lub hauv paus paj hlwb, ua rau nws yog ib qho tseem ceeb rau kev kawm neuroprotection, neural plasticity, thiab neurotransmitter tswj. Nws cov ntawv thov tseem ceeb tsom mus rau kev tswj hwm kev ua haujlwm neuronal thiab kev tshawb nrhiav cov txheej txheem pathological ntawm cov kab mob neurodegenerative.
Hauv kev tshawb fawb txog kev ua haujlwm neuronal, ACTH (4-10) feem ntau siv hauvhauv vitroKev sim ntawm tes los tshuaj xyuas nws cov teebmeem ntawm neuronal ciaj sia, kev loj hlob, sib txawv, thiab synaptic plasticity. Cov kev tshawb fawb tau pom tias peptide no txhawb nqa cov phosphorylation ntawm qhov kev hloov pauv CREB los ntawm kev ua kom lub adenylate cyclase (AC)-cyclic adenosine monophosphate (cAMP)-protein kinase A (PKA) taw qhia txoj hauv kev, yog li txhawb kev qhia ntawm lub hlwb-derived neurotrophic factor (BDNF). Raws li ib qho tseem ceeb neurotrophic yam, BDNF ho txhawb nqa neuronal ciaj sia taus, synaptic kev loj hlob, thiab txij nkawm ntawm plasticity, muab cov pov thawj tseem ceeb sim rau nws cov neuroprotective mechanism.
Piv txwv li, hauvhauv vitroCov qauv kev raug mob neuronal raug ntxias los ntawm oxygen-glucose deprivation (OGD), kev kho mob nrog ACTH (4-10) cuam tshuam neuronal apoptosis, txhawb kev qhia ntawm cov tshuaj tiv thaiv apoptotic Bcl-2, txo qis cov protein apoptotic Bax, thiab txo qis kev puas tsuaj neuronal, nteg lub hauv paus rau kev tshawb fawb tom qab.
Hauv kev tshawb nrhiav cov txheej txheem pathological ntawm cov kab mob neurodegenerative, ACTH (4-10) tau siv dav hauv cov qauv tsiaj ntawm Alzheimer's kab mob, Parkinson's disease, thiab lwm yam kab mob. Nyob rau hauv nas dementia qauv induced los ntawm amyloid- (A), intraperitoneal txhaj ntawm ACTH (4-10) rau 4 lub lis piam sib law liag txo A deposition thiab tau hyperphosphorylation nyob rau hauv nas hlwb thiab upregulates synaptophysin qhia. Morris dej tshawb nrhiav kev kuaj pom tseeb tias qhov kev khiav tawm latency ntawm pab pawg kho tau luv luv los ntawm 35%, thiab lub sijhawm siv nyob rau hauv lub hom phiaj quadrant yog ob npaug, qhia meej meej tias nws txoj kev txawj ntse-txhim kho cov teebmeem thiab cuam tshuam txog cov txheej txheem pathological.
Tsis tas li ntawd, nyob rau hauv nas qauv ntawm tus kab mob Parkinson, peptide no tiv thaiv dopaminergic neurons nyob rau hauv substantia nigra thiab alleviates lub cev muaj zog dysfunction, muab ib tug tseem ceeb cov cuab yeej rau kev soj ntsuam cov pathogenesis thiab kev cuam tshuam lub hom phiaj ntawm Parkinson tus kab mob.
(2) Endocrine thiab Stress Response Research
Raws li ib feem ntawm ACTH, ACTH (4-10) tsis muaj lub luag haujlwm tseem ceeb ntawm ACTH nyob rau hauv stimulating cortisol secretion, tab sis nws muaj peev xwm tswj tsis tau cov hypothalamic-pituitary-adrenal (HPA) axis. Yog li ntawd, nws yog dav siv nyob rau hauv cov kev tshawb fawb ntawm HPA axis kev tswj thiab kev ntxhov siab teb. HPA axis yog lub cev tseem ceeb ntawm endocrine axis rau kev ntxhov siab; Nws overactivation ua rau muaj qhov txawv txav cortisol ntau ntau, uas ua rau hippocampal neurons puas tsuaj thiab ua rau lub hlwb tsis zoo, kev xav tsis zoo, thiab lwm yam teeb meem.
Hauv kev tshawb fawb, ACTH (4-10) feem ntau yog siv los tsim cov qauv tsiaj txhu ntsig txog kev ntxhov siab thiab tshawb nrhiav nws cov kev tswj xyuas thiab cov txheej txheem ntawm HPA axis. Cov kev sim paub meej tias cov peptide no txo qis ACTH ntau dhau los ntawm pituitary los ntawm inhibiting hypothalamic corticotropin-releasing hormone (CRH) tso tawm, yog li txo qis adrenal cortisol tso zis thiab tiv thaiv kev mob hypercortisolism-induced puas rau cov ntaub so ntswg thiab kabmob. Cov cuab yeej no ua rau nws muaj txiaj ntsig zoo rau kev kawm txog cov kab mob endocrine thiab kev puas siab puas ntsws los ntawm kev ntxhov siab ntev. Tsis tas li ntawd, cov kev tshawb fawb tau pom tias ACTH (4-10) tuaj yeem tswj hwm qhov sib npaug ntawm cov neurotransmitter hauv kev ntxhov siab, txhawb kev tso tawm ntawm excitatory neurotransmitters xws li dopamine thiab acetylcholine, txo qis cov teebmeem inhibitory ntau dhau ntawm -aminobutyric acid (GABA), thiab txhim kho cov teeb liab kis tau zoo hauv neural circuits, muab cov tswv yim tshiab ntawm kev ntxhov siab.
(3) Kev tshawb fawb txog kev tiv thaiv kab mob thiab kab mob
ACTH (4-10) tuaj yeem tswj hwm lub cev tiv thaiv kab mob ua haujlwm thiab cov lus teb inflammatory los ntawm kev khi rau MC1R, MC3R, thiab MC5R ntawm lub cev tiv thaiv kab mob, ua rau nws siv dav hauv kev tshawb fawb txog kev tiv thaiv kab mob thiab kab mob. Nws cov txheej txheem tseem ceeb suav nrog inhibiting pro-inflammatory factor tso tawm thiab tswj kev tiv thaiv kab mob sib txawv.
Hauv kev tshawb fawb txog kev mob inflammatory, ACTH (4-10) feem ntau siv rau hauv kev tsim thiab kev cuam tshuam ntawm ntau yam kab mob. Piv txwv li, nyob rau hauv cov tsiaj qauv ntawm tus txha caj qaum raug mob (SCI), kev kho mob nrog ACTH (4-10) txo qhov kev qhia ntawm pro-inflammatory yam xws li IL-6 thiab IL-8 ntawm qhov chaw raug mob. Qhov tseem ceeb, hauv SCI qauv hnyav, IL-6 thiab IL-8 qib hauv pawg kho mob 3-teev qis dua li cov hauv 6-teev pab pawg, lees paub tias nws txo qis kev puas tsuaj tom qab txha caj qaum los ntawm kev tiv thaiv kev mob thiab muab pov thawj tseem ceeb rau kev tshawb nrhiav cov txheej txheem inflammatory thiab cov tswv yim cuam tshuam rau SCI.
Hauvhauv vitroKev sim tshuaj tiv thaiv kab mob hauv lub cev, qhov peptide no inhibits kev ua haujlwm ntau dhau ntawm macrophages thiab T hlwb, txo qis kev tso tawm ntawm pro-inflammatory yam xws li qog necrosis factor- (TNF-) thiab IL-6, txhawb kev qhia ntawm cov tshuaj tiv thaiv kab mob xws li IL-10, tswj T-cell sib txawv, thiab inhibits Th17 cell overactivation cov cuab yeej siv tshuaj tiv thaiv kab mob.
Cov ntawv thov hauv Kev Txhim Kho Tshuaj
Raws li cov txheej txheem compact active peptide, ACTH (4-10) nthuav tawm cov kev ua haujlwm lom neeg muaj zog, tsis muaj tshuaj lom thiab cov kev mob tshwm sim, thiab cov ntshav-hlwb tsis zoo permeability. Nws cov ntsiab lus tseem ceeb (His-Phe-Arg-Trp) tau koom nrog lwm cov melanocortin peptides xws li -melanocyte-stimulating hormone (-MSH), ua kom muaj kev khi rau ntau yam melanocortin receptors. Yog li nws tau dhau los ua cov khoom lag luam zoo tshaj plaws rau kev txhim kho tshuaj peptide, tam sim no tsom mus rau neuroprotective, cognition-enhancing, anti-inflammatory / immunomodulatory, thiab tshuaj tiv thaiv kev ntxhov siab, nrog ntau yam kev ua tiav hauv tsev kho mob.
(1) Kev Txhim Kho Cov Tshuaj Neuroprotective
Neuroprotection sawv cev rau txoj kev loj hlob tshuaj zoo tshaj plaws rau ACTH (4-10), tsom rau cov hlab ntsha raug mob xws li ischemic stroke, mob hlwb raug mob, thiab txha caj qaum, nrog rau cov kab mob neurodegenerative nrog rau Alzheimer's disease thiab Parkinson's disease. Nws txo qis kev tsis taus thiab ncua kev kis kab mob los ntawm inhibiting neuronal apoptosis, alleviating o, thiab txhawb kev puas hlwb kho.
Hauv kev txhim kho cov tshuaj raug mob rau cov hlab ntsha, ACTH (4-10) muaj qhov zoo ntawm cov ntshav-hlwb thaiv kev nkag mus sai, kev txiav txim ncaj qha rau cov neeg raug mob neurons, thiab tsawg kawg toxicity.
Piv txwv li, nyob rau hauv nas nruab nrab cerebral hlab ntsha occlusion (MCAO) qauv, intracerebroventricular txhaj ntawm ACTH (4-10) ua rau cov qhab nia qis dua neurological deficit ntawm 72 teev tom qab reperfusion, kwv yees li 40% txo qis hauv cerebral infarct ntim, txo apoptosis hauv cheeb tsam hippocampal, 1 pawg tswj hwm CA. lees paub tias nws muaj zog tiv thaiv kev raug mob ntawm lub paj hlwb ischemic thiab muab cov kev sim ua kom muaj zog rau kev txhim kho tshuaj tom ntej.
Rau kev raug mob ntawm tus txha caj qaum, ACTH (4-10) txhawb kev ua haujlwm rov qab los ntawm kev tiv thaiv kev mob thiab txo cov neuronal apoptosis; nws cov derivatives tau nkag mus rau kev kuaj tshuaj toxicity preclinical, uas qhia tau hais tias muaj peev xwm txhais tau zoo.
Hauv kev txhim kho kab mob neurodegenerative tshuaj, ACTH (4-10) ncua kev kis kab mob los ntawm ntau lub hom phiaj. Rau Alzheimer's kab mob, nws txo A deposition, inhibits tau hyperphosphorylation, txhawb neurotrophic yam qhia, thiab txhim kho kev txawj ntse muaj nuj nqi. Rau Parkinson tus kab mob, nws tiv thaiv dopaminergic neurons nyob rau hauv substantia nigra thiab alleviates lub cev muaj zog dysfunction. Preclinical kev tshawb fawb ntawm lwm yam derivatives tau ua tiav theem kev nce qib, nrog qee qhov hloov kho peptides qhia txog cov teebmeem neuroprotective hauv cov qauv tsiaj.
(2) Kev Txhim Kho Kev Paub-Kev Txhim Kho Tshuaj
Raws li nws cov kev tswj xyuas cov teebmeem ntawm lub hauv nruab nrab lub paj hlwb, ACTH (4-10) muaj txiaj ntsig zoo hauv kev paub txog kev txhim kho tshuaj, tsom rau Alzheimer's kab mob, vascular dementia, me me kev txawj ntse, thiab lwm yam mob. Nws txhim kho kev kawm, kev nco, thiab kev paub txog kev ua haujlwm los ntawm kev txhim kho kev sib kis ntawm synaptic, txhawb kev qhia txog neurotrophic, thiab ntsuas cov tshuaj neurotransmitters.
Cov kev tshawb fawb hauv tsev kho mob qhia tau tias ACTH (4-10) txhim kho lub sijhawm ntev (LTP) hauv hippocampus thiab txhawb nqa synaptic plasticity. Txij li thaum lub hippocampus yog lub hauv paus ntawm lub paj hlwb rau kev kawm thiab kev nco, txhim kho synaptic plasticity ho txhim kho kev txawj ntse.
Tsis tas li ntawd, cov peptide no tswj hwm qhov sib npaug ntawm cov paj hlwb hauv nruab nrab, txhawb kev tso tawm ntawm excitatory neurotransmitters xws li dopamine thiab acetylcholine, txhim kho neural circuit signaling, thiab alleviates kev txawj ntse poob. Hauv kev sim tib neeg, cov kev kawm tau txais ACTH (4-10) tau pom tias muaj kev txhim kho ntau dua hauv cov tshuaj tiv thaiv lub sijhawm ua haujlwm tsis tu ncua piv nrog cov placebo pab pawg, lees paub nws lub peev xwm los txo kev ntxhov siab ntawm lub hlwb thiab txhim kho kev mloog thiab teb ceev, muab pov thawj kev kho mob rau kev paub txog kev txhim kho tshuaj. Tam sim no, cov kws tshawb fawb tau hloov kho ACTH (4-10) txhawm rau txhim kho kev ruaj ntseg thiab ntshav-hlwb thaiv permeability; cov kev paub-txhim kho cov teebmeem ntawm cov derivatives uas muaj feem xyuam tau raug lees paub hauv cov qauv tsiaj dementia, uas qhia tau tias muaj kev cia siab rau kev kho mob txhais lus.
(3) Kev Txhim Kho Cov Tshuaj Tiv Thaiv Kab Mob thiab Immunomodulatory
Raws li nws cov tshuaj tiv thaiv kab mob thiab kev tiv thaiv kab mob, ACTH (4-10) muaj kev cia siab dav hauv kev tsim tshuaj rau cov kab mob autoimmune thiab inflammatory kab mob, xws li mob caj dab rheumatoid, ntau yam sclerosis, inflammatory plob tsis so tswj kab mob, thiab lwm yam mob tom qab tus txha caj qaum raug mob. Nws alleviates cov tsos mob thiab slows kab mob kev loj hlob los ntawm suppressing o thiab restore lub cev muaj zog tshuav nyiaj li cas.
Hauv kev tsim cov tshuaj tiv thaiv kab mob autoimmune, ACTH (4-10) txo qis autoimmune-mediated cov ntaub so ntswg puas los ntawm kev tswj T-cell sib txawv thiab inhibiting pro-inflammatory factor tso tawm.
Rau ntau yam sclerosis, nws inhibits lub cev tiv thaiv kab mob ntawm myelin sheaths, txo neuroinflammation, thiab khaws cia muaj nuj nqi neural; Cov kev tshawb fawb preclinical paub meej tias nws qhov ua tau zoo hauv kev txo cov tsos mob hauv cov qauv tsiaj, tso lub hauv paus rau kev sim tshuaj tom ntej. Nyob rau hauv cov kab mob inflammatory plob tsis so tswj, nws suppresses plab hnyuv mucosal o, txo pro-inflammatory yam tso tawm, thiab txhawb kev kho mucosal, thiab tam sim no nyob rau hauv cov tsiaj validation. Rau qhov mob thib ob tom qab raug mob qaum qaum, ACTH (4-10) txo cov neuron puas tsuaj los ntawm kev txo qis IL-6, IL-8, thiab lwm yam pro-inflammatory, muab cov tshuaj tshiab tsim kho rau SCI.
(4) Peptide Modification thiab Delivery System Optimization
Haiv neeg ACTH (4-10) raug kev txom nyem los ntawm enzymatic degradation, luv luv hauv vivo ib nrab-lub neej (kwv yees li 0.5 teev), thiab tsis muaj bioavailability, uas txwv tsis pub siv tshuaj kho mob. Yog li ntawd, kev hloov pauv peptide thiab kev xa khoom kom zoo tau dhau los ua cov lus qhia tseem ceeb hauv nws txoj kev tsim tshuaj. Tam sim no, cov kws tshawb fawb feem ntau siv tshuaj hloov kho thiab xa cov khoom thauj los txhim kho kev ruaj ntseg, txuas ntxiv ib nrab lub neej, thiab txhim kho lub hom phiaj.
Rau kev hloov kho tshuaj, cov tswv yim muaj xws li amino acid residue methylation, PEGylation, thiab lipidation. Piv txwv li, methylation ntawm N-terminal methionine thiab C-terminal palmitoylation ntawm ACTH (4-10) txuas ntxiv nws hauv vivo ib nrab-lub neej mus rau 3 teev hauv cov tsiaj sim, nce ntshav-hlwb barrier nkag mus rau 65%, thiab ua rau muaj kev cuam tshuam zoo rau kev xav hauv cov qauv kev nyuaj siab ntev yam tsis muaj kev phom sij.
Tsis tas li ntawd, kev hloov kho ntawm cov kab ke nquag tuaj yeem txhim kho lub hom phiaj rau cov melanocortin receptors tshwj xeeb, txo cov teebmeem ntawm lub hom phiaj, thiab txhim kho kev kho mob.
Rau kev xa khoom kom zoo, kev tswj xyuas qhov ntswg thiab kev xa khoom nanocarrier yog kev tshawb fawb hotspots. Kev tswj qhov ntswg tiv thaiv kab mob siab ua ntej-pass metabolism thiab yooj yim rau kev tswj tus kheej. Nrog rau kev nqus tau zoo xws li dimethyl--cyclodextrin, qhov ntswg bioavailability ntawm ACTH (4-10) derivatives tuaj yeem nce ntxiv los ntawm ntau dua 5-fold, txhim kho kev nqus ntawm lub cev. Nanocarrier tus me nyuam tiv thaiv peptide los ntawm enzymatic degradation, ua rau lub hom phiaj xa khoom, ua rau kom muaj zog hauv zos ntawm qhov chaw mob, thiab txo cov kev mob tshwm sim. Cov txheej txheem xa khoom cuam tshuam tau nkag mus rau qhov kev lees paub ua ntej, muab kev txhawb nqa tseem ceeb rau kev kho mob txhais lus ntawm ACTH (4-10)-raws li tshuaj.
Raws li ib feem tseem ceeb ntawm ACTH, ACTH (4-10) qhia tau hais tias dav siv rau hauv kev tshawb fawb, kev tsim tshuaj, thiab kev pab kho mob vim nws cov qauv kev cog lus, kev ua kom muaj roj ntsha ntshiab, thiab tsis muaj tshuaj lom. Nrog rau kev nce qib hauv peptide hloov kho thiab xa cov thev naus laus zis, nws hauv vivo ruaj khov, bioavailability, thiab lub hom phiaj yuav raug txhim kho ntxiv, muaj peev xwm ua kom nrawm dua kev kho mob txhais lus thiab muab cov tswv yim kho tshiab rau neurodegenerative, autoimmune, thiab inflammatory kab mob.
Lub caij no, feem ntau cov ntawv thov tam sim no ntawm ACTH (4-10) tseem nyob ntawm qhov kev tshawb fawb theem pib lossis qib preclinical. Kev nyab xeeb mus sij hawm ntev thiab kev ua tau zoo ntawm tib neeg xav tau kev kuaj xyuas dav dav. Tsis tas li ntawd, cov teeb meem xws li enzymatic degradation thiab luv luv ib nrab-lub neej ntawm haiv neeg ACTH (4-10) yuav tsum tau hais txog, nrog kev hloov pauv peptide thiab kev xa khoom kom zoo raws li cov lus qhia tseem ceeb rau yav tom ntej. Tsis tas li ntawd, ACTH (4-10) yog siv rau kev tshawb fawb nkaus xwb thiab tsis yog rau tib neeg kev siv. Tag nrho cov txheej txheem kev sim thiab kev txhim kho tshuaj yuav tsum ua raws li cov kev cai cuam tshuam kom muaj kev nyab xeeb thiab kev tshawb fawb nruj.
Hauv cov ntsiab lus, raws li ntau lub luag haujlwm peptide tawg, ACTH (4-10) tau nthuav dav nws daim ntawv thov thiab kev tshawb fawb tob. Nws xav kom ua tiav kev siv dav hauv biomedicine, kev tu tawv nqaij, thiab lwm yam kev lag luam yav tom ntej, muab kev txhawb nqa tseem ceeb rau tib neeg kev noj qab haus huv thiab kev txhim kho kev lag luam.
FAQ
ACTH theem twg yog hais txog?
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Rau cov qauv thaum sawv ntxov, cov kws paub txog kev noj qab haus huv xav txog 10–60 picograms ib milliliter (pg/mL), lossis 1.3–16.7 picomoles ib liter (pmol/L), raws li ib txwm muaj. Cov txiaj ntsig no yuav txawv me ntsis nyob ntawm chav kuaj. Cov qib siab ntawm ACTH yuav qhia tau tias ib tus neeg muaj tus kab mob Cushing lossis Addison tus kab mob.
Puas yog ACTH qis li qub?
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Tsawg los yog ib txwm ACTH thiab qis cortisol yog ib qho cim ntawm hypopituitarism. Qhov no txhais tau hais tias cov qog pituitary lossis kev puas tsuaj rau koj lub caj pas pituitary yuav tiv thaiv nws los ntawm kev ua kom txaus ACTH. Yog tias tsis muaj ACTH txaus, koj cov qog adrenal tsis tau txhawb kom muaj cortisol txaus. Nyob rau tib lub sijhawm, lawv tuaj yeem txo qis.
Cim npe nrov: Acth (4-10), lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom