Phenylbutazone, tseem hu ua "bute," yog ib qho tshuaj uas tsis yog-steroidal anti-inflammatory tshuaj (NSAID) uas nquag siv hauv cov tshuaj equine los kho cov mob musculoskeletal-hais txog mob thiab mob. Kev txiav txim siab txoj cai koob tshuaj phenylbutazone rau tus pony yog qhov tseem ceeb los lav nws txoj kev muaj peev xwm thaum txwv qhov kev xav tau tshwm sim. Hauv tsab ntawv blog no, peb yuav tham txog ntau npaum li cas phenylbutazone yuav tsum tau muab rau cov nees thiab teb qee cov lus nug nquag nug txog kev siv nws li cas.
Pom zoo npaum li cas ntawm Phenylbutazone rau Nees?
Kev ntsuas qhov ntsuas ntawm phenylbutazone rau ponies tuaj yeem hloov pauv mus rau ob peb lub ntsiab lus, suav nrog tus pony qhov hnyav, qhov hnyav ntawm tus mob tau hais txog, thiab cov kev cai tshwj xeeb ntawm tus pony. Nquag, tus qauv koob tshuaj ntawmCov tshuaj phenylbutazonerau ponies yog nruab nrab ntawm 2.2 mus rau 4.4 mg ib kilogram ntawm lub cev qhov hnyav txhua hnub. Nyob ntawm cov lus qhia ntawm tus kws kho tsiaj, qhov koob tshuaj no tuaj yeem muab rau hauv ib lossis ob zaug sib faib. Phenylbutazone, piv txwv li, yuav raug muab tshuaj txhua hnub rau ib tus nees hnyav 500 kilograms (kwv yees li 1100 phaus) ntawm koob tshuaj xws li 1100 mg txog 2200 mg.
Nws yog ib qho tseem ceeb kom tus kws kho tsiaj cov kev daws teeb meem thiab cov cai thaum saib xyuas phenylbutazone. Mus deb dhau los yog rub tawm kev siv phenylbutazone tuaj yeem ua rau muaj kev cuam tshuam loj heev, suav nrog kev mob plab hnyuv, mob raum, thiab pob txha pob txha zais. Txhawm rau kom ua tiav cov txiaj ntsig kev xav tau, nws yog qhov tseem ceeb uas yuav tsum siv cov tshuaj qis tshaj plaws rau lub sijhawm luv tshaj plaws. Kev kuaj xyuas ib txwm los ntawm tus kws kho tsiaj kuj tseem ceeb heev los lav tus pony txoj kev noj qab haus huv thiab hloov qhov ntsuas yog tias tsim nyog. Los ntawm kev ua raws li cov lus qhia no nruj me ntsis, qhov kev pheej hmoo ntawm kev tsis zoo raug txo kom tsawg thiab tus nees tus mob raug tswj kom muaj kev nyab xeeb thiab zoo.
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Yuav Siv Phenylbutazone npaum li cas rau Nees?
Kev nkag siab txog kev rov ua haujlwm ntawm lub koom haum yog qhov tseem ceeb rau kev siv tau zoo thiab nyab xeebCov tshuaj phenylbutazonehauv ponies. Qhov hnyav ntawm tus mob raug kho thiab tus nees cov lus teb rau cov tshuaj txiav txim qhov zaus ntawm kev tswj hwm phenylbutazone. Los ntawm thiab loj, phenylbutazone tuaj yeem tswj tau ntau dua ib lub sijhawm hauv ib hnub. Piv txwv li, nyob rau hauv lub caij nyoog uas tag nrho cov tawm ib hnub rau ib hnub yog 4.4 mg / kg, nws nyhav muab raws li ib tug ib feem los yog muab faib ua ob koob tshuaj ntawm 2.2 mg / kg txhua.
Phenylbutazone tuaj yeem siv ob zaug hauv ib hnub los pab tswj cov ntshav ntau ntxiv ntawm cov tshuaj, uas tuaj yeem pab tswj kev mob thiab mob ntev. Qhov kev npaj noj tshuaj no tau lees paub tias qhov txiaj ntsig zoo ntawm cov tshuaj tau txais kev txhawb nqa nyob rau ib hnub, muab kev txo qis rau tus pony. Txawm li cas los xij, rau qhov xwm txheej hnyav lossis tsis tshua muaj mob hnyav, ib feem ntawm ib hnub yuav txaus los ua kom tiav qhov zoo tagnrho.
Nws yog ib qho tseem ceeb kom ua raws li tus kws kho tsiaj cov lus qhia los txiav txim qhov kev npaj noj tshuaj zoo tshaj plaws rau txhua tus pony. Tus nees tus mob tshwj xeeb, kev noj qab haus huv tag nrho, thiab cov lus teb rau cov tshuaj yuav raug txiav txim siab los ntawm tus kws kho tsiaj. Kev ua raws li lub koom haum pom zoo rov ua dua txwv tsis pub muaj kev twv txiaj tom qab thiab lav qhov kev tiv thaiv thiab muaj zog siv phenylbutazone. Kev soj ntsuam thiab sau ntawv nrog tus kws kho tsiaj yog qhov tseem ceeb los hloov qhov ntsuas thiab rov tshwm sim ntawm ib rooj plaub, lav qhov txiaj ntsig zoo tshaj plaws rau tus pony.
Dab tsi yog Qhov Muaj Peev Xwm tshwm sim ntawm Phenylbutazone hauv Nees?
Thaum phenylbutazone muaj kev vam meej hauv kev saib xyuas kev mob thiab khaus khaus hauv ponies, nws yog ib qho tseem ceeb kom paub txog nws qhov kev xav tau tom qab. Cov tsos mob tshwm sim yog dab tsiCov tshuaj phenylbutazonehauv ponies?
Zoo li txhua yam tshuaj uas tsis yog tshuaj steroidal anti-inflammatory (NSAIDs), phenylbutazone tuaj yeem muaj ntau yam kev phiv, tshwj xeeb tshaj yog thaum siv rau lub sijhawm ntev lossis ntau npaum li cas. Cov kev tsis zoo tshwm sim feem ntau muaj xws li:
Nws muaj peev xwm ua rau phenylbutazone ua rau mob plab thiab colic los ntawm irritating lub plab ntawm txoj hnyuv. Cov kev mob tshwm sim tuaj yeem suav nrog kev tshaib plab zuj zus, txo qhov hnyav, thiab plab tsis xis nyob.
Kev siv cov phenylbutazone tuaj yeem cuam tshuam rau lub raum muaj peev xwm, tshwj xeeb tshaj yog nyob rau hauv tau txais cov ponies qhuav los yog cov neeg mob raum dhau los. Kev soj ntsuam lub raum muaj peev xwm los ntawm kev kuaj ntshav yog qhov tseem ceeb thaum siv phenylbutazone.
Phenylbutazone tuaj yeem cuam tshuam cov pob txha pob txha, ua rau txo qis kev tsim cov platelets. Qhov no tuaj yeem ua rau muaj hlau tsis txaus, leukopenia (txo qis platelets dawb), thiab thrombocytopenia (qis platelets).
Txawm tias tsis tshua muaj, phenylbutazone tuaj yeem ua rau daim siab mob hauv ponies. Lethargy, tsis qab los noj mov, thiab siab siab enzymes nyob rau hauv cov ntshav kuaj tej zaum yuav tag nrho cov cim ntawm tus mob no, uas yuav ua tau ib tug kos npe rau ntawm daim siab cell raug mob los yog o. Jaundice yog yellowing ntawm daim tawv nqaij thiab ob lub qhov muag.
Phenylbutazone tuaj yeem ua rau ua kua dej thiab ua kom loj, tshwj xeeb tshaj yog nyob rau hauv appendages. Txhawm rau txwv qhov kev twv txiaj ntawm cov txiaj ntsig tom qab, phenylbutazone yuav tsum tau siv ntawm qhov ua tau zoo tshaj plaws rau qhov luv luv ntawm qhov tseem ceeb. Kev kuaj xyuas ib txwm los ntawm tus kws kho tsiaj, suav nrog kev kuaj ntshav thiab ntsuas qhov tseeb, tuaj yeem pab txheeb xyuas qhov cuam tshuam tsis zoo thaum ntxov thiab hloov kho cov phiaj xwm raws li xav tau.
Xaus
Phenylbutazoneyog ib qho kev kho mob zoo rau nees qhov mob thiab mob, tab sis nws yuav tsum tau siv nrog ceev faj kom tsis txhob muaj kev phiv. Phenylbutazone feem ntau yog muab rau nees ntawm koob tshuaj 2.2 txog 4.4 mg / kg ib hnub, ib zaug lossis ob zaug hauv ib hnub, nyob ntawm cov lus qhia ntawm tus kws kho tsiaj. Txhawm rau kom ntseeg tau tias phenylbutazone siv tau zoo thiab muaj txiaj ntsig, nws yog qhov tseem ceeb kom nkag siab tag nrho cov kev mob tshwm sim thiab saib xyuas tus nees noj qab haus huv.
Los ntawm kev ua raws li tus kws kho tsiaj cov lus qhia thiab saib xyuas tus pony cov tshuaj tiv thaiv rau cov tshuaj, cov tswv cuab tuaj yeem pab lawv cov ponies kom ua tiav kev txo qis los ntawm kev mob siab thiab khaus khaus thaum txwv cov kev phom sij cuam tshuam nrog kev siv phenylbutazone.
Cov ntaub ntawv
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