nkag siab qhov txawv
Atropine thiab atropine sulfateyog siv tsis tu ncua pauv pauv, tab sis lawv tsis zoo ib yam. Atropine yog qhov tshwm sim tiag tiag tropane alkaloid extricated los ntawm kev txaus ntshai nightshade (Atropa belladonna) thiab lwm yam nroj tsuag ntawm tsev neeg Solanaceae. Ntawm qhov tod tes, atropine sulfate yog sulfate ntsev thav duab ntawm atropine, feem ntau siv hauv cov tshuaj vim nws qhov ruaj khov thiab solubility.
pharmacology thiab kev kho mob siv
Atropine, nyob rau hauv txhua rooj plaub ntawm nws cov ncej, ua raws li ib tug kev sib tw nrog sib tw ntawm acetylcholine ntawm muscarinic receptors nyob rau hauv lub parasympathetic apprehensive moj khaum. Qhov kev ua no los txog hauv kev cuam tshuam ntawm lub cev tsis siv neeg lub cev muaj peev xwm qhia los ntawm parasympathetic moj khaum, xws li abating ntawm lub plawv dhia thiab unwinding ntawm cov leeg du.
Hauv tshuaj,atropine thiab atropine sulfatenrhiav kev sib txawv. Lawv feem ntau siv los nthuav cov understudies rau kev kuaj qhov muag, kho bradycardia (mob plawv dhia), kom txo qis salivation thiab ua pa tawm thaum phais, thiab xyuas cov kev cuam tshuam ntawm paj hlwb neeg ua hauj lwm. Atropine sulfate yog siv dhau rau hauv ophthalmology los kho qee qhov muag qhov muag.
antropine yog ib qho tshuaj uas muaj ob peb yam txiaj ntsig
Kev kho mob ntawm bradycardia
Atropine tuaj yeem nce lub plawv dhia los ntawm kev thaiv cov haujlwm ntawm acetylcholine, ib qho neurotransmitter uas ua rau lub plawv dhia.
01
Kev tswj ntawm arrhythmias
Atropine tuaj yeem muab kev pabcuam los tswj cov mem tes tsis sib xws los ntawm kev tswj cov hluav taws xob hauv lub plawv.
02
Txo cov kev mob hawb pob
Atropine tuaj yeem ua rau cov nqaij ntshiv ntawm txoj kev aviation, ua rau nws yooj yim ua pa rau cov tib neeg uas muaj mob hawb pob lossis lwm yam mob ua pa.
03
Diminishment ntawm kev tso tawm
Atropine tuaj yeem txo qhov tsim ntawm ntuav, tawm hws, thiab bronchial tawm, uas tuaj yeem ua tau zoo rau cov neeg mob uas muaj qhov tsis zoo los yog tawm ntawm kev phais.
04
Kev kho mob
Atropine tuaj yeem siv los ua kev kho mob rau qee yam kev puas tsuaj, xws li tshuaj tua kab organophosphate lossis cov paj hlwb raug.
05
Siv hauv tshuaj loog
Atropine nquag siv thaum phais kom qhuav cov pa tawm thiab cia siab tias bradycardia tshwm sim los ntawm cov tshuaj loog.
06
Kev tswj ntawm kev txav kev nyuaj siab
Atropine tuaj yeem muab kev pabcuam los txo cov kev mob tshwm sim ntawm kev txav mus los, xws li kev tsis sib haum xeeb thiab xeev siab.
07
qhov sib txawv ntawm kev txhais thiab kev tswj hwm
Ib qho ntawm qhov sib txawv tseem ceeb ntawmatropine thiab atropine sulfateyog lawv nthuav dav thiab koom haum. Atropine sulfate, ua ntsev, yog dej-soluble ntau dua li atropine, uas cuam tshuam nws cov tshuaj pharmacokinetics thiab yooj yim ntawm kev siv hauv kev kho mob. Atropine sulfate feem ntau nkag mus rau hauv cov duab txhaj tshuaj rau cov hlab ntsha, intramuscular, lossis subcutaneous lub koom haum, nrog rau hauv kev kho mob rau lub qhov muag.
sab cuam tshuam thiab ceev faj
Ob qho tib si atropine thiab atropine sulfate tuaj yeem ua rau muaj kev cuam tshuam, tshwj xeeb tshaj yog thaum siv hauv kev ntsuas siab lossis rau lub sijhawm qeeb. Cov kev mob tshwm sim no tuaj yeem suav nrog lub qhov ncauj qhuav, qhov muag tsis pom, nthuav lub plawv dhia, tu tso zis, thiab txhaws. Cov neeg mob uas muaj qee yam kev kho mob, xws li glaucoma, hyperthyroidism, lossis kab mob plawv, tej zaum yuav muaj feem ntau dua ntawm kev cuam tshuam los ntawm atropine lossis atropine sulfate.
cov ntsiab lus subtle tseem ceeb ntawm kev hwm rau nws cov ntawv thov
Bradycardia
Atropine yog siv los ua kom lub plawv dhia hauv cov xwm txheej uas lub plawv dhia zoo li maj mam, xws li ntawm bradycardia lossis qee yam ntawm lub plawv. Nws ua haujlwm los ntawm kev thaiv cov muscarinic receptors uas yuav ua rau lub plawv tsis zoo los ntawm txoj hlab ntsha vagus.
01
Arrhythmias
Hauv qee hom arrhythmias, atropine tuaj yeem pab ua kom lub plawv dhia tsis tu ncua, tshwj xeeb tshaj yog thaum lub plawv dhia tsis zoo vim muaj kev cuam tshuam ntawm lub plawv.
02
Mob hawb pob
Atropine tuaj yeem muab kev pab rau cov neeg uas muaj mob hawb pob lossis lwm yam mob ua pa los ntawm kev so cov leeg nqaij ib ncig ntawm txoj hlab pas, txo qis spasm, thiab ua pa yooj yim dua.
03
Ntxim qab heev
Atropine txo qis qis xws li qaub ncaug thiab bronchial mucus los ntawm inhibiting qhov kev txiav txim ntawm acetylcholine ntawm muscarinic receptors hauv qog.
04
Poisoning Antidote
Atropine yog ib qho tshuaj tua kab mob rau qee yam tshuaj lom, tshwj xeeb tshaj yog cov tshuaj tua kab organophosphate thiab cov paj hlwb raug, uas ua rau muaj kev ua haujlwm ntawm acetylcholine los ntawm inhibiting acetylcholinesterase.
05
Tshuaj loog
Thaum lub sij hawm phais, atropine yuav siv tau los ua kom qhuav cov secretions thiab tiv thaiv bradycardia vim los ntawm cov tshuaj loog los yog vagal stimulation.
06
Motion Sickness
Atropine tuaj yeem siv prophylactically los txo cov tsos mob ntawm kev mob kev ua haujlwm, nrog rau kiv taub hau thiab xeev siab, los ntawm kev txo qis cov hlab ntsha hauv vestibular.
07
Cov txheej txheem gastrointestinal
Atropine tuaj yeem siv ua ntej cov txheej txheem hauv plab hnyuv kom txo qis kev txav mus los thiab zais cia, ua kom yooj yim rau kev kuaj mob xws li endoscopy.
08
Tshuaj kho mob ua ntej
Atropine tuaj yeem muab ua ntej kev phais kom txo qis qhov ncauj thiab pharyngeal secretions, yog li txo qhov kev pheej hmoo ntawm kev mob ntsws.
09
Cov menyuam kawm ntawv Dilation
Rau kev kuaj mob lub hom phiaj, atropine tuaj yeem siv los nthuav tawm cov menyuam kawm ntawv thaum kuaj qhov muag, txawm hais tias nws tsis yog thawj tus neeg sawv cev rau qhov kev qhia no vim nws cov kev mob tshwm sim.
10
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias kev siv atropine yuav tsum tau ua tib zoo tswj hwm los ntawm cov kws kho mob vim tias nws tuaj yeem muaj cov kev mob tshwm sim tseem ceeb, suav nrog qhov ncauj qhuav, qhov muag tsis pom kev, tso zis nyuaj, thiab ntau npaum li cas, delirium thiab hnov lus. Tsis tas li ntawd, atropine yuav tsum tau siv ceev faj rau cov neeg mob uas muaj qee yam mob xws li glaucoma, prostate o, lossis kab mob plawv. Raws li nrog rau txhua yam tshuaj, koob tshuaj thiab kev tswj hwm yuav tsum ua raws li cov lus qhia kev tshaj lij thiab coj mus rau hauv tus account tus neeg mob tus yam ntxwv thiab contraindications.
xaus
Hauv kev xaus, thaum atropine thiab atropine sulfate muaj feem xyuam nrog cov tshuaj zoo sib xws, lawv tsis zoo ib yam. Atropine sulfate yog ib daim ntawv ntsev ntawm atropine, feem ntau siv rau hauv cov tshuaj rau nws cov stability thiab solubility. Kev nkag siab qhov sib txawv ntawm ob hom no yog qhov tseem ceeb rau lawv txoj kev nyab xeeb thiab siv tau zoo hauv kev kho mob.
Yog xav paub ntxiv txogatropine sulfatethiab nws cov kev siv kho mob, thov hu rau Sales@bloomtechz.com.
cov ntaub ntawv
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007927/
https://pubmed.ncbi.nlm.nih.gov/25029935/
https://www.sciencedirect.com/science/article/abs/pii/S2214718116302099