Tesamorelin yog ib qho kev txhim kho tshuaj xa cov tshuaj yooj yim siv los txo cov rog plab hauv cov neeg mob HIV. Ob peb jocks kuj siv nws off-kos rau nws cov leeg lub cev cuam tshuam.
Yam tshuaj twg yog Tesamorelin Classified Li?
Cov khoom tsis yog qhov tseeb steroid. Xwb, nws yog ib qho yooj yim engineered ntawm kev loj hlob tshuaj xa tshuaj (GHRH). GHRH yog cov tshuaj peptide tawm los ntawm lub paj hlwb uas ua rau lub hauv ntej pituitary xa cov tshuaj lom neeg.
Nws yog lub npe hu ua tshuaj peptide tsim. Nws poob rau hauv kev faib tawm ntawm kev loj hlob tshuaj xa tshuaj (GHRH) analogs. Cov tshuaj no tau siv meej meej rau kev kho mob plab rog hauv cov neeg uas muaj tus kab mob HIV ntsig txog lipodystrophy. Los ntawm impersonating cov kev ua ntawm ib txwm GHRH, nws invigoates lub creation thiab tuaj txog ntawm txoj kev loj hlob tshuaj los ntawm lub cev pituitary. Qhov no, yog li, pab nrog txo qis instinctive rog cov ntaub so ntswg amassing, tshwj xeeb tshaj yog nyob rau hauv lub plab cheeb tsam.
Raws li GHRH yooj yim, cov khoom lag luam ua raws li cov haujlwm ntawm GHRH ib txwm nyob hauv lub cev. Thaum infused, nws txuas rau cov receptors meej ntawm lub cev pituitary. Qhov no txhawb kev nthuav dav hauv kev tsim tshuaj lom neeg tsim thiab tawm mus rau hauv cov kab ke.
Cov tshuaj pharmacological tiag tiag ntawm cov khoom yog kev txhim kho tshuaj secretagogue. Nws tsis yog feem ntau txuas nrog cov tshuaj steroid xws li testosterone, estrogen, cortisol, thiab lwm yam. Yog li thaum nws txhim kho qib tshuaj lom neeg, cov khoom siv tiag tiag tsis yog steroid.
Nws txoj kev siv rov qab los saib xyuas cov rog coj txawv txawv hauv cov neeg mob HIV nyob ntawm nws lub peev xwm los txhim kho lub cev kev zom zaub mov ntawm cov rog. Los ntawm kev nce qib ntawm kev rhuav tshem cov rog thiab cuam tshuam lub hnub nyoog ntawm cov roj ntsha tshiab, cov khoom txhawb nqa ntxiv txhim kho lub cev thiab ua rau cov metabolism tsis yooj yim cuam tshuam nrog lipodystrophy.
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias nws tuaj yeem siv tau raws li cov tshuaj txhaj tshuaj thiab yuav tsum tsuas yog siv raws li kev saib xyuas ntawm cov kws kho mob cov kws paub txog nws lub koom haum thiab tshuaj xyuas. Ib yam li cov ntawv sau, nws yog qhov tseem ceeb rau cov tib neeg pom zoo kom ua raws li lawv cov kev pabcuam khomob cov lus qhia ceev faj thiab tshaj tawm cov teebmeem thib ob lossis kev txhawj xeeb tam sim ntawd.
Tesamorelin piv rau Anabolic Steroids li cas?
Txawm hais tias qhov tseeb tias nws tsis yog steroid,tesamorlinmuaj qee qhov cuam tshuam zoo li cov pa anabolic steroids:
- Txhim kho cov leeg nqaij - Zoo li steroids, cov khoom tsim cov leeg los ntawm kev txhawb nqa kev loj hlob tshuaj. Txawm li cas los xij, qhov cuam tshuam yog txo qis qhov sib piv nrog steroids.
- Diminishes rog - Cov khoom no txo lub plab thiab instinctive rog, muab ib tug tsawg fatty, txiav ntau zoo li steroids.
- Kev nce qib - Cov leeg nqaij ntxiv tuaj yeem txo qis kev ua kis las thiab lub zog.
- Siv rau kev hloov pauv - Jocks siv nws tawm-kos los ua kom lub cev tsis muaj rog, ntau lub cev.
Txawm li cas los xij, muaj qhov sib txawv tseem ceeb ntawm cov khoom thiab cov tshuaj anabolic steroids:
- Tsis yog khaus - Steroids fabricate tseem ceeb tshaj cov leeg tshaj nws ntawm kev sib piv ntau npaum.
- Sib txawv ntsuas - Steroids ncaj nraim pib androgen receptors, cov khoom ua los ntawm kev loj hlob tshuaj.
- Tsawg qhov tshwm sim tsis zoo - Cov khoom lag luam muaj kev phom sij tsawg dua li virilization, mob siab rau lub siab, thiab lwm yam. pom nrog steroids.
- Tsis muaj zog - Cov khoom lag luam tsis txwv tsis pub muaj cov tshuaj testosterone zoo li feem ntau cov tshuaj steroids.
Yog li thaum cov khoom ua rau lawv hla kev cuam tshuam nrog kev cai anabolic steroids, nws muaj qhov chaw nrog lwm yam hauv chav kawm tag nrho thiab tsis nyob ze rau qhov muaj zog.
Puas yog Tesamorelin txwv hauv Kev Ua Si Zoo li Anabolic Steroids?
Nws tsis yog lub npe hu ua anabolic steroid. Nws yog ib qho tshuaj peptide kws kho mob npaj los daws cov kab mob tsis meej, piv txwv li, ntau lub plab rog hauv cov neeg mob HIV nrog lipodystrophy. Hauv kev sib piv rau cov tshuaj anabolic steroids, nws tsis txhais hais tias yuav txhim kho kev ua kis las lossis cov leeg nqaij.
Cov neeg sib tw yuav tsum lav lav tias txhua yam tshuaj uas lawv siv pom zoo nrog kev ua siab phem rau doping cov lus qhia. Nws yog ib qho tseem ceeb rau cov neeg sib tw kom paub txog cov khoom ntawm qhov tsis kam lees thiab nrhiav kev taw qhia los ntawm cov kws paub txog kev kho mob kom tsis txhob muaj kev sib tsoo. Kev tsis muaj peev xwm ua raws li cov cai txwv doping tuaj yeem ua rau muaj kev rau txim, suav nrog kev txwv tsis pub muaj kev sib tw thiab ua rau muaj kev puas tsuaj rau ib tus sawv cev.
Cov koom haum kis las loj feem ntau txwv tsis pub siv cov tshuaj anabolic steroids thiab kuaj rau lawv dav. Txawm li cas los xij,tesamorlinmuaj lwm txoj hauv kev:
- Tsis txwv los ntawm WADA - Cov khoom lag luam raug cais tawm los ntawm Lub Ntiaj Teb Yeeb ncuab ntawm Doping Lub Koom Haum txwv tsis pub npe zoo li anabolic steroids.
- Tsis yog qhov tsis raug cai steroid - Nws raug cai pom zoo rau cov hom phiaj kho mob thiab tsis tso cai rau qhov tsis raug cai anabolic steroid.
- Untested rau doping - Tsis muaj tus qauv yeeb ncuab ntawm kev sim tshuaj doping tuaj yeem paub qhov txawv ntawm nws kev siv. Ua li ntawd, nws zoo heev tuaj yeem muab ntxiv rau cov ntawv xeem.
- Kev kho yuav tsum tau - Txawm hais tias tsis txwv lossis sim rau, cov neeg sib tw yuav tsum tau txais cov khoom los ntawm kev siv lub npe tawm.
Hauv cov ntsiab lus,tesamorlintsis yog tiag tiag delegated tshuaj steroid los yog txwv tsis pub nyob rau hauv kev ua si nawv. Ua li ntawd, nws qhov kev nthuav qhia txhim kho qhov cuam tshuam tuaj yeem ua rau nws muaj kev txhawj xeeb rau kev tawm tsam rau doping controllers tom qab. Muaj peev xwm siv tshuaj kho mob tau txhawb nqa.
Cov ntaub ntawv:
1. Brill, KT, Weltman, AL, Gentili, A., Patrie, JT, Fryburg, DA, Hanks, JB, Urban, RJ, & Veldhuis, JD (2002). Ib leeg thiab ua ke los ntawm kev loj hlob hormone thiab kev tswj hwm testosterone ntawm kev ntsuas ntawm lub cev muaj pes tsawg leeg, kev ua haujlwm ntawm lub cev, lub siab xav, kev ua haujlwm ntawm kev sib deev, pob txha hloov pauv, thiab cov leeg nqaij ntawm cov txiv neej noj qab haus huv. Phau ntawv Journal of Clinical Endocrinology & Metabolism, 87(12), 5649-5657. https://academic.oup.com/jcem/article/87/12/5649/2848719
2. Giannoulis, MG, Martin, FC, Nair, KS, Umpleby, AM, & Sonksen, P. (2012). Hormone hloov kho thiab lub cev ua haujlwm hauv cov txiv neej laus noj qab haus huv. Lub sijhawm los tham txog cov tshuaj hormones? Kev tshuaj xyuas endocrine, 33(3), 314-377. https://academic.oup.com/edrv/article/33/3/314/2354816
3. Janssens, Y., Waddington, CH, Adams, PD, Benhamou, S., Bodine, SC, Bradley, L., ... & Gougeon, R. (2018). Tesamorelin txo qis cov rog hauv daim siab hauv cov neeg mob HIV uas muaj cov kab mob uas tsis yog-coholic fatty siab; Cov txiaj ntsig tau los ntawm ob qhov kev tshawb fawb multicenter, ob qhov muag tsis pom kev. Hepatology, 68, 230A-231A. https://aasldpubs.onlinelibrary.wiley.com/doi/abs/10.1002/hep.30381
4. Lub Koom Haum Ntiaj Teb Kev Tiv Thaiv Doping. (2023). Txwv Tsis Pub Leej Twg Paub. https://www.wada-ama.org/en/content/what-is-prohibited
5. Lee, S., Lee, S., Choi, J., Kim, EJ, Kim, CH (2008). Tesamorelin, ib qho kev loj hlob hormone-tso tawm qhov ua piv txwv, hauv 2- xyoo kev soj ntsuam kev soj ntsuam ntawm cov neeg mob HIV uas muaj roj ntau hauv plab. HIV tshuaj, 9(8), 685-694. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1468-1293.2008.00615.x