Ib qho tshuaj uas paub zoo uas tsis yog tshuaj tiv thaiv kab mob (NSAID) nrog rau cov tshuaj tua kab mob thiab tshuaj tiv thaiv kab mob yogCov tshuaj phenylbutazone, tseem hu ua "bute." Txawm hais tias qhov tseeb tias nws yog thawj zaug tsim rau tib neeg siv, nws txoj kev muaj peev xwm txo qis kev ntxhov siab thiab khaus khaus tam sim ntawd kis mus rau veterinary tshuaj. Ponies feem ntau tau txais "bute" los ua kom pom kev tsis txaus ntseeg thiab cov leeg nqaij sab nraud cuam tshuam txog kev tsim txom. Txawm hais tias nws siv dav, nws muaj peev xwm tshwm sim, xws li teeb meem nrog lub plab zom mov thiab lub raum puas tsuaj, yuav tsum tau ceev faj txog kev noj tshuaj. Nws siv rau tib neeg tau txo qis txawm tias muaj kev nyab xeeb dua; Txawm li cas los xij, vim nws cov txiaj ntsig kho tau zoo, nws tseem yog ib qho tseem ceeb hauv cov tshuaj equine.
Cov xwm txheej twg tuaj yeem kho Phenylbutazone?
Nws tau raug sau tseg rau ntau yam kev mob nkeeg hauv tib neeg thiab tsiaj txhu, ua tsaug rau nws cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob. Cia peb tshawb txog ntau yam ntawm cov xwm txheej uas nws nquag siv.
Mob thiab mob
Cov khoom no feem ntau yog siv los kho mob thiab mob los ntawm cov kab mob musculoskeletal xws li mob caj dab, tendonitis, thiab bursitis. Los ntawm kev tawm tsam kev tsim cov prostaglandins,Cov tshuaj phenylbutazonetxo qhov khaus thiab txo kev tsim txom, ua rau nws muaj zog rau kev saib xyuas kev sib koom ua ke tsis tu ncua thiab firmness.
Lameness nyob rau hauv Nees
Tej zaum nws yog qhov nrov tshaj plaws rau nws siv hauv ponies los kho qhov tsis muaj zog thiab cov leeg nqaij sab nraud. Nees ua rau raug mob thiab tej yam mob xws li laminitis thiab navicular syndrome, tshwj xeeb tshaj yog thaum koom nrog cov kev ua ub no xws li kev sib tw lossis dhia. Phenylbutazone txo qhov mob thiab mob hauv cov nees, tso cai rau lawv rov zoo thiab rov ua haujlwm li qub.
Fever txo
Cov khoom lag luam tsis tsuas yog muaj cov tshuaj tua kab mob thiab tiv thaiv kab mob, tab sis nws kuj muaj cov tshuaj tua kab mob, uas txhais tau hais tias nws tuaj yeem txo tus neeg kub taub hau. Vim li no, nws tuaj yeem siv los kho tib neeg thiab tsiaj febrile tej yam kev mob, xws li kab mob los yog inflammatory kab mob nrog kub taub hau.
Phenylbutazone ua haujlwm li cas?
Cov khoom no ua haujlwm los ntawm kev thaiv kev tsim cov prostaglandins, uas yog lipid compounds koom nrog kev mob, mob, thiab kub taub hau, los ntawm inhibiting enzyme cyclooxygenase (COX). Los ntawm kev txo qis ntawm cov qib ntawm prostaglandins, nws txo qis kev tsim txom, txo qis kev ua kom hnyav, thiab ua npaws qis, muab kev pab cuam rau cov xwm txheej sib txawv.
Inhibition ntawm Prostaglandin Synthesis
Prostaglandins yog chij atoms uas suav tias yog qhov tseem ceeb hauv kev kho kev khaus khaus, kev tsim txom kev xav, thiab kev kub taub hau. Lawv raug tsim nyob rau hauv lub teeb ntawm cov ntaub so ntswg raug mob los yog khaus thiab ua nyob rau hauv lub zos mus rau vasodilation, increment vascular penetrability, thiab sharpen torment receptors. Cov khoom no txo qhov mob, mob, thiab kub taub hau los ntawm inhibiting prostaglandin synthesis los ntawm inhibiting COX enzymes.
Cov teebmeem analgesic
Lub hauv paus paj hlwb lub peev xwm los hloov kho qhov mob nkag siab thiab inhibit prostaglandin synthesis yog lub hauv paus ntawm nws cov teebmeem analgesic. Los ntawm kev txo qis ntawm kev tsim cov prostaglandins ntawm qhov chaw ntawm aggravation, cov khoom pab txo qis sharpening ntawm torment receptors, nqa txog kev pab los ntawm tsis xis nyob. Tsis tas li ntawd, nws tuaj yeem siv cov txiaj ntsig ncaj qha rau txoj hauv kev tsim txom hauv lub siab thiab tus txha caj qaum, ntxiv txhim kho nws cov txiaj ntsig kho mob.
Anti-inflammatory teebmeem
Irritation yog ib tug complex physiological cov tshuaj tiv thaiv rau cov ntaub so ntswg raug mob los yog kis kab mob, portrayed los ntawm liab, nthuav, siv, thiab tsim txom. Los ntawm kev txhawb nqa vasodilation thiab nce vascular permeability, prostaglandins ua lub luag haujlwm tseem ceeb hauv cov txheej txheem inflammatory thiab nyiam cov kab mob hauv lub cev mus rau qhov chaw raug mob. Los ntawm kev cuam tshuam prostaglandin sib xyaw, cov khoom lag luam hoses cov tshuaj tiv thaiv incendiary, txo qhov loj thiab tsim txom cuam tshuam nrog cov xwm txheej provocative.
Dab tsi yog qhov txaus ntshai thiab kev mob tshwm sim ntawm Phenylbutazone?
Thaum nws tuaj yeem ua tiav rau kev saib xyuas kev mob hnyav thiab hnyav, nws tsis yog yam tsis muaj kev twv txiaj, tshwj xeeb tshaj yog nrog kev siv ntev los yog siv ntau. Nkag siab txog cov txiaj ntsig xav tau thiab contraindications ntawm nws yog qhov tseem ceeb rau kev tiv thaiv thiab siv tau.
Gastrointestinal Side Effects
Phenylbutazone, zoo li lwm cov tshuaj uas tsis yog tshuaj steroidal anti-inflammatory (NSAIDs), tuaj yeem ua rau mob plab hnyuv xws li gastritis, rwj, thiab los ntshav. Kev siv cov khoom lag luam qeeb tuaj yeem cuam tshuam qhov npog ntawm lub plab thiab plab zom mov, ua rau kev txhim kho ntawm cov kab mob lossis kev puas tsuaj. Cov khoom yuav tsum tau noj nrog cov zaub mov los yog tshuaj antacids thiab ntawm qhov tsawg kawg nkaus koob tshuaj kom tsawg li sai tau kom txo tau qhov kev pheej hmoo ntawm kev mob plab hnyuv.
Cov teebmeem rau lub raum
Cov khoom lag luam thiab lwm yam tshuaj uas tsis yog tshuaj tiv thaiv kab mob (NSAIDs) tuaj yeem ua rau lub raum tsis ua haujlwm, tshwj xeeb tshaj yog rau cov neeg uas lub cev qhuav dej lossis twb muaj kab mob raum. Nws tuaj yeem txo cov zis tso zis thiab tej zaum yuav ua rau mob raum raug mob los ntawm kev txo cov ntshav hauv lub raum thiab ua rau sodium thiab dej tuav. Cov neeg mob yuav tsum tau kuaj xyuas kom pom tseeb ntawm lub raum tawg, piv txwv li, kev hloov pauv hauv cov txiaj ntsig ntawm kev tso zis lossis kev kuaj lub raum, thaum siv nws.
Hematological teebmeem
Nws tau cuam tshuam nrog cov teebmeem hematological theem nrab, suav nrog cov pob txha pob txha zais thiab cov ntshav dyscrasia, piv txwv li, aplastic hlau deficiency, leukopenia, thiab thrombocytopenia. Txawm hais tias lawv tsis tshua muaj tshwm sim, cov teebmeem no tuaj yeem ua rau hnyav thiab tuag taus. Thaum noj cov khoom, cov neeg mob yuav tsum tau qhia kom nrhiav kev kho mob yog tias lawv muaj cov tsos mob xws li qaug zog, los ntshav, lossis nqaij tawv tsis muaj laj thawj.
Vim tias muaj peev xwm ua rau muaj kev cuam tshuam loj heev, nws yog ib qho tseem ceeb rau ob tus neeg mob thiab cov chaw kho mob kom ceev faj. Qee qhov xwm txheej, cov ntshav suav yuav tsum tau kuaj xyuas tsis tu ncua txhawm rau txhawm rau txhawm rau txhawm rau txhawm rau pom cov tsos mob ntawm hematological txawv txav. Kev tso tseg cov tshuaj sai li sai tau yuav tsum tau txiav txim siab thaum muaj kev hloov pauv tseem ceeb hauv cov ntshav tsis tau.
Cov khoom yog ib tug muaj zog anti-inflammatory thiab mob reliever, tab sis nws siv yuav tsum tau ua tib zoo txiav txim siab nyob rau hauv lub teeb ntawm muaj peev xwm ntawm tsis zoo hematological tshwm sim. Cov kev phom sij no yuav tsum tau piav qhia tag nrho rau cov neeg mob, thiab lawv yuav tsum tau qhia seb cov tsos mob dab tsi los nrhiav. Qhov no guarantees yooj yim kho mob intercession, raws li txo qhov tshwm sim ntawm loj intricacies. Hauv kev xaus, txawm tias nws tuaj yeem ua tau zoo heev, nws yog ib qho tseem ceeb kom paub txog nws thiab ua tib zoo saib xyuas kom tsis txhob muaj kev phiv loj heev.
Xaus
Phenylbutazoneyog ib qho NSAID khaus uas muaj qhov mob nyem, txo qis, thiab tshuaj tua kab mob. Nws nquag siv los kho ntau yam mob 'ua npaws, o, thiab mob. Nyob rau hauv cov tshuaj kho tsiaj, nws tau pom tau hais tias muaj kev vam meej hauv kev kho cov leeg nqaij sab nrauv thiab faltering nyob rau hauv ponies, tig mus rau hauv lub staple nyob rau hauv lub teb. Txawm li cas los xij, kev txhawj xeeb txog kev nyab xeeb thiab muaj cov NSAIDs tshiab nrog kev txhim kho kev nyab xeeb tau txo nws txoj kev siv hauv tib neeg cov tshuaj.
Cov khoom tuaj yeem pab tau ntau, tab sis nws los nrog qee qhov kev pheej hmoo, tshwj xeeb tshaj yog tias siv rau lub sijhawm ntev lossis ntau npaum li cas. Kev tsis haum tshuaj, ntshav tsis txaus, muaj teeb meem hauv plab hnyuv xws li rwj thiab los ntshav, thiab teeb meem raum yog tag nrho cov kev mob tshwm sim. Nws yuav tsum tau siv nrog ceev faj thiab nyob rau hauv kev saib xyuas ntawm ib tug kws kho mob kom paub tseeb tias nws muaj kev nyab xeeb thiab siv tau zoo.
Txawm hais tias tib neeg siv tau tsawg dua, nws tseem yog ib qho tseem ceeb hauv cov tshuaj kho tsiaj, qhov uas nws txaus los saib xyuas kev mob thiab tsis muaj zog hauv ponies tseem raug pom. Nws cov txiaj ntsig zoo thiab cov txiaj ntsig ua rau nws muaj txiaj ntsig zoo hauv kev kho tsiaj, txawm tias nws qhov chaw tsis zoo rau tib neeg kev kho mob.
Cov ntaub ntawv
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