Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm vasopressin 20 units hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo vasopressin 20 units rau muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Raws li ib qho tseem ceeb ntawm endogenous neuropeptide active tshuaj nyob rau hauv lub cev, vasopressin (CAS: 11000-17-2, molecular mis C₄₆H₆₅N₁₅O₁₂S₂, cyclic nine-amino-acidpeptide daim ntawv cog lus ruaj khov nrog polypeptide dispensable conformation nyob rau hauv physiological aqueous ib puag ncig, thiab kev lag luam muajvasopressin 20 unitsKev txhaj tshuaj yog ib qho kev kho mob tshwj xeeb uas tau npaj los ntawm cov khoom siv peptide refined. Nws physiological kev tswj scope yog deb tshaj ib tug dimension. Nws ib txwm ua lub luag haujlwm tseem ceeb tab sis tseem ceeb hauv kev tswj hwm tus cwj pwm neural thiab kev saib xyuas kev ua haujlwm ntawm lub plab zom mov.
Qhov kev tswj hwm no feem ntau khiav los ntawm ntau qhov sib txuas ntawm kev ua haujlwm ntawm lub cev hauv lub cev, thiab muaj qhov tshwj xeeb thiab kev sib koom ua ke. Cov tshuaj peptide no tso siab rau nws qhov tshwj xeeb cyclic molecular qauv kom ua tiav cov hom phiaj hauv zos mus rau cov ntaub so ntswg tshwj xeeb uas tau muab faib rau ntawm cov hlab ntsha thiab plab hnyuv cov leeg nqaij. Los ntawm kev cuam tshuam hauv ntau qhov tseem ceeb xws li kev sib kis tau zoo ntawm cov teeb liab synaptic, kev tswj hwm ntawm kev sib txawv ntawm tes, thiab kev ua haujlwm ntawm cov leeg nqaij, nws tsim ib tus choj rau kev sib txuas ntawm neural thiab somatic functions, muab kev txhawb zog rau kev sib koom ua ke homeostasis ntawm lub cev neural somatic system.
Cov Khoom Muag Khoom
Vasopressin COA
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| Certificate of Analysis | ||
| Compound npe | Vasopressin | |
| Qib | Pharmaceutical qib | |
| CAS Nr. | 9034-50-8 | |
| Ntau | 38g | |
| Ntim txheem | PE hnab + Al foil hnab | |
| Chaw tsim tshuaj paus | Shaanxi BLOOM TECH Co., Ltd | |
| Ntau No. | 202601090086 | |
| MFG | Peb 9, 2026 | |
| EXP | Peb 8, 2028 | |
| Qauv |
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| Yam khoom | Enterprise txheem | Kev txheeb xyuas qhov tshwm sim |
| Qhov tshwm sim | Dawb los yog yuav luag dawb hmoov | Ua raws |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 5.0% | 0.54% |
| Poob rau ziab | Tsawg dua lossis sib npaug li 1.0% | 0.42% |
| Hnyav Hlau | Pb Tsawg dua lossis sib npaug li 0.5ppm | N.D. |
| Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Hg Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Cd Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Purity (HPLC) | Ntau dua lossis sib npaug li 99.0% | 99.98% |
| Ib leeg impurity | <0.8% | 0.52% |
| Tag nrho microbial suav | Tsawg dua lossis sib npaug li 750cfu / g | 95 |
| E. Coli | Tsawg dua lossis sib npaug li 2MPN / g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (los ntawm GC) | Tsawg dua lossis sib npaug li 5000ppm | 500ppm ua |
| Cia | Khaws rau hauv qhov chaw kaw, tsaus, thiab qhuav hauv qab -20 degree | |
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| Tshuaj Formula | C43H67N15O12S2 | |
| Exact Mass | 1049.45 | |
| Molecular Luj | 1050.22 | |
| m/z | 1049.45 (100.0%), 1050.46 (46.5%), 1051.46 (10.6%), 1051.45 (9.0%), 1050.45 (5.5%), 1052.45 (4.2%), 1051.45 (2.6%), 1051.46 (2.5%), 1050.45 (1.6%), 1052.46 (1.6%), 1052.46 (1.1%) | |
| Elemental Analysis | C, 49.18; H, 6.43; N, 20.01; O, 18.28; S, 6.11 | |
Piv nrog rau ntau hom neuropeptide tebchaw uas ua rau muaj kev hloov pauv sai, ntse ntawm lub cev tom qab khi rau lub hom phiaj receptors, vasopressin nthuav dav me ntsis thiab ntau cov kev tswj hwm zoo hauv cov kab mob lom. Tsis zoo li ceev ceev - ua yeeb yam neuropeptides uas coj cov kev hloov pauv ntawm lub cev tam sim ntawd, vasopressin tsis tshua muaj kev hloov pauv sai, ua haujlwm tsis zoo hauv lub sijhawm luv luv. Hloov chaw, nws pheej koom nrog ntev -lub sij hawm, zoo-granular physiological modulation nyob rau hauv ntau lub cev, tsis tu ncua calibrating ntsig txog cov teeb liab transduction txoj kev los tiv thaiv qhov tsis tu ncua, kom ua tiav ntawm ntau hom kev ua haujlwm ntawm lub cev hauv lub cev.
Cov kev sib tham tom ntej no tsom mus rau ob txoj kev tshawb fawb tseem ceeb xws li kev tswj hwm kev coj tus cwj pwm zoo thiab cov hlab plawv-kev hloov pauv hauv plab hnyuv. Los ntawm kev sib koom ua ke cov hom phiaj receptor tis, downstream molecular cascade cov tshuaj tiv thaiv, cov ntaub ntawv kev sim cellular thiab hauv vivo physiological xeem cov ntsiab lus, tsab xov xwm nthuav dav unpacks vasopressin lub pob zeb kev tswj txoj hauv kev, cov yam ntxwv ua haujlwm thiab cov khoom siv tshuaj hauv lub cev hauv cov qauv physiological.
Neurobehavioral regulatory teebmeem thiab multidimensional mediating txoj kev
Qhov no yog tsim los ntawm thaj tsam hypothalamic thiab tuaj yeem tso ncaj qha rau hauv neural microenvironment ntawm lub hlwb. Nws ua diffusely ntawm ntau qhov ntawm lub hauv paus paj hlwb network kom ua tiav cov kev cai ntawm ntau yam kev coj cwj pwm. Nws txoj hauv kev ua haujlwm yog ntau- kev taw qhia thiab tshwj xeeb, thiab tuaj yeem muab faib ua cov hauv qab no:
01.Kev cuam tshuam thiab kev tswj hwm kev sib tham hauv zej zog
Cov tshuaj peptide no tuaj yeem cuam tshuam rau kev lees paub, kev sib cuam tshuam, thiab kev coj tus cwj pwm ntawm tib neeg los ntawm kev tswj hwm cov teeb liab synaptic hauv thaj chaw xws li limbic system, hippocampus, thiab lub hlwb. Kev tshawb fawb tau pom tias qhov kev hloov pauv hloov pauv hauv nws qhov kev tso tawm tuaj yeem cuam tshuam rau tib neeg txoj kev sib raug zoo lossis kev coj tus cwj pwm zam, thiab koom nrog hauv kev tsim thiab tswj kev sib raug zoo hauv zej zog. Cov kev cai no tsis ncaj qha ua tus coj tus cwj pwm tawm, tab sis ua kom zoo rau kev coj tus cwj pwm zoo los ntawm kev nplua -tuning neural excitability.
02.Lub neural mediated mechanism ntawm kev sib deev tsav.
Vasopressin 20 unitstuaj yeem ua rau cov nuclei ntsig txog kev yug me nyuam hauv nruab nrab lub paj hlwb, cuam tshuam rau kev siv zog ntawm kev sib deev thiab kev pib ntawm kev xeeb tub hauv cov tib neeg los ntawm kev tswj hwm kev tso tawm suab paj nruag ntawm neurotransmitters. Cov kev cai no muaj qhov sib txawv ntawm poj niam txiv neej, thiab txoj hauv kev neural koom nrog nws cov teebmeem sib txawv me ntsis ntawm cov tib neeg sib txawv. Txawm li cas los xij, nws cov txiaj ntsig tseem ceeb yog los tswj cov kev xav ntawm lub cev ib txwm muaj cuam tshuam nrog kev xeeb tub thiab muab kev txhawb nqa neural rau cov pej xeem txuas ntxiv.
03.Qhov kev sib koom ua ke ntawm kev sib txuas ua ke
Thaum lub sijhawm tsim kev sib raug zoo ntawm kev sib raug zoo ntawm cov tib neeg ntawm tib chav kawm, nws tuaj yeem txhim kho synaptic plasticity ntawm cov txheej txheem neural, sib sau ua ke ntawm cov neeg koom nrog kev nco, thiab txo qhov tsis muaj kev sib raug zoo ntawm kev sib raug zoo. Cov txiaj ntsig no tsis yog luv luv - cov txiaj ntsig tam sim ntawd, tab sis yog tus neeg nruab nrab tseem ceeb hauv kev tsim cov kev sib raug zoo ntawm tus kheej los ntawm kev tswj hwm kev sib kis ntawm cov teeb liab neural nyob rau lub sij hawm ntev, ua kom muaj kev ruaj ntseg ntawm kev sib txuas ua ke.
03.Peptide kev cai ntawm niam txiv kev nyuaj siab teb
Thaum cev xeeb tub lig thiab lactation, qib ntawm nws tso tawm los ntawm hypothalamus yuav nce ntxiv. Nws tuaj yeem pab niam hloov mus rau tom qab yug menyuam lub cev thiab kev coj tus cwj pwm los ntawm kev tswj hwm kev ntxhov siab hauv nruab nrab-txoj kev cuam tshuam ntawm neural txoj hauv kev, txo cov kev cuam tshuam ntawm kev ntxhov siab ntawm niam txiv tus cwj pwm, thiab muab kev txhawb nqa neural rau kev loj hlob ntawm leej niam tus cwj pwm xws li kev tiv thaiv tus menyuam thiab pub niam mis, txo qhov cuam tshuam tsis zoo ntawm kev ntxhov siab ntawm kev sib txuas ntawm niam mos.
Sib sau ua ke, lub hauv paus zais cia vasopressin ua rau ntau yam -faceted neuroregulatory functions ntawm lub hom phiaj khi rau cov cheeb tsam ntawm lub paj hlwb thiab txawv neural signaling txoj kev. Nws tsim intraspecies social dynamics los ntawm tuning limbic thiab hippocampal synaptic kev ua ub no los tswj kev sib raug zoo nyiam; modulates poj niam txiv neej-divergent reproductive drive los ntawm kev tswj cov neurotransmitter secretion nyob rau hauv reproductive-sociated hlwb nuclei; stabilizes ntev -lub sij hawm monogamous khub sib cog lus los ntawm boosting synaptic plasticity kom solidify associative social nco; thiab surges thaum lub sij hawm cev xeeb tub lig thiab lactation kom tsis txhob muaj niam txiv hauv nruab nrab kev ntxhov siab, tiv thaiv kev coj tus cwj pwm thiab niam tsis zoo- kev sib raug zoo ntawm tus menyuam mos.
Peptide tswj cov teebmeem ntawm cov hlab plawv thiab plab hnyuv physiological functions
Vasopropressin txoj cai ntawm lub plawv thiab plab hnyuv system feem ntau tsom rau kev tswj hwm cellular homeostasis thiab tswj cov leeg nqaij. Los ntawm lub hom phiaj tshwj xeeb ntawm tes, nws ua tiav cov kev cai ntawm lub plawv plab hnyuv muaj nuj nqi.
Kev tu thiab sib txawv induction ntawm myocardial cell homeostasis
Cov tshuaj peptide no tuaj yeem ua haujlwm tshwj xeeb ntawm cov hlwb ua ntej los ntawm kev ua kom cov txheej txheem kev tswj hwm intracellular, ua rau lawv cov kev qhia sib txawv rau hauv cov hlwb laus, thiab ntxiv rau kev rov ua dua tshiab thiab kho cov hlab plawv. Nyob rau tib lub sijhawm, nws tuaj yeem tswj cov teeb liab hloov pauv hauv cov hlwb myocardial, inhibit qhov txawv txav ntawm apoptosis, tswj cov kev ua haujlwm ntawm lub cev ntawm cov hlwb myocardial, ua kom cov txheej txheem kev ncaj ncees thiab kev ua haujlwm ruaj khov ntawm cov ntaub so ntswg myocardial, thiab zam kev ua haujlwm txawv txav los ntawm myocardial homeostasis imbalance.
Kev txhawb nqa ntawm plab hnyuv du nqaij contraction thiab peristalsis
Vasopressin 20 unitstuaj yeem ua rau cov leeg nqaij du hauv phab ntsa plab hnyuv, los ntawm kev tswj cov kev hloov pauv hauv cov calcium ion concentration hauv intracellular, txhim kho lub zog contraction thiab rhythmicity ntawm cov nqaij ntshiv, thiab yog li txhawb kev nce qib thiab tshem tawm cov ntsiab lus ntawm plab hnyuv. Txoj cai no yog qhov chaw- tshwj xeeb thiab muaj kev txhawb nqa tseem ceeb ntawm cov leeg nqaij leeg hauv txoj hnyuv thiab lwm qhov chaw. Nws tuaj yeem ua kom zoo dua cov kab mob plab hnyuv peristalsis los ntawm kev sib koom ua ke ntawm cov leeg nqaij thiab plab hnyuv phab ntsa hlab ntsha, ua kom muaj kev loj hlob ntawm kev zom zaub mov thiab kev nqus, thiab zam kev zom zaub mov tsis zoo tshwm sim los ntawm qeeb plab hnyuv peristalsis.
Yog li ntawd, ib tug standard chaw kho mob npaum li cas ntawmasopressin 20 unitsua haujlwm raws li qhov tseem ceeb tshaj plaws endogenous signaling mediator bridging central paj hlwb kev ua ub no thiab peripheral somatic metabolism, nyob rau hauv ib tug indispensable tseem ceeb xwm txheej nyob rau hauv hloov maj mam physiological modulation ntawm neurobehavioral kev ua ub no nrog rau kev txhawb nqa homeostasis ntawm plawv plawv thiab gastrointestinal visceral functions. Nws nyob rau hauv -vivo pharmacological modulation yeej tsis nyob ntawm kev sib cais ib qho kev taw qhia cascade. Hloov chaw, vasopressin ua kom muaj kev cuam tshuam txog kev lom neeg ntawm ntau yam - phiaj.
Ntau - txoj hauv kev sib koom ua ke uas npog ntau qhov sib txawv ntawm cov neurobehavioral domains: xws li los ntawm kev hloov pauv kev sib raug zoo ntawm ib tus neeg nyiam thiab tswj kev sib kis ntawm neurochemical hauv qab ntawm kev sib deev arousal, pab txhawb kev sib koom ua ke ntawm kev sib koom ua ke ntawm lub cim xeeb circuits, kom txo tau ntau dhau ntawm lub cev hloov pauv ntawm lub hlwb ua rau muaj kev ntxhov siab. Parallel rau cov teebmeem neuroregulatory, no polypeptide hormone concurrently koom nyob rau hauv myocardial cell sib txawv induction thiab ntev -lub sij hawm cardiomyocyte homeostasis preservation.Tsis tas li ntawd, vasopressin khi rau tej vasopressin receptor subtypes faib rau gastrointestinal smooth nqaij cell daim nyias nyias los modulate contractile.
Kho cov leeg nro thiab calibrate lub suab nrov zaus ntawm plab hnyuv peristalsis, yog li txhim kho lub plab zom mov tsis sib haum xeeb thiab ua kom lub plab zom mov ib txwm muaj.By synchronizing multi- phiaj xwm lom cuam tshuam thoob plaws hauv nruab nrab lub paj hlwb, cov ntaub so ntswg plawv thiab cov plab hnyuv siab raum los ntawm cov kab mob sib txawv ntawm cov kab mob hauv cov kab mob hauv cov kab mob sib txawv - cov kab mob sib txawv ntawm cov kab mob hauv cov hlab ntsha, cov kab mob hauv cov hlab ntsha thiab cov kab mob digestive. systematic multi-organ synergistic regulation. Cov txheej txheem txheej txheem txheej txheem no ua rau cov tshuaj hormones ua tiav kev tswj hwm thiab ua kom zoo tshaj plaws uas npog ntau lub cev ntawm lub cev: kev ua haujlwm zoo ntawm lub cev, ntev -lub sij hawm cardiomyocyte tus qauv thiab kev ua haujlwm ruaj khov, nrog rau kev ua haujlwm ruaj khov ntawm plab hnyuv peristalsis.
Cov ntaub ntawv
Interplay of Angiotensin Peptides, Vasopressin, thiab Insulin hauv plawv: Kev sim thiab cov ntaub ntawv pov thawj ntawm kev hloov pauv hauv kev rog rog thiab ntshav qab zib mellitus, Int J Mol Sci, 2024, 25: 1310
Oxytocin thiab vasopressin neural networks: cuam tshuam rau kev coj tus cwj pwm sib txawv thiab kev txhais lus neuroscience, Neurosci Biobehav Rev, 2017, 76(pt A): 87-98
Vasopressin txhaj, DailyMed, 2025
Kev Tshawb Fawb Txog Kev Tshawb Fawb: Vasopressin thiab cov hlab plawv ntu 2 - kev kho mob physiology (https://pmc.ncbi.nlm.nih.gov/articles/PMC420051/)
Cov teebmeem ntawm trifluoperazine ntawm kev ua haujlwm thiab cov qauv ntawm cov zis tso zis tso zis. Lub luag haujlwm ntawm calmodulin vasopressin- txhawb nqa dej permeability.(https://pmc.ncbi.nlm.nih.gov/articles/PMC370615/)
FAQ
- Kev txhaj tshuaj vesopressin siv rau dab tsi?
Kev txhaj tshuaj Vasopressin yog ib qho tseem ceeb vasoactive kev npaj npaj rau ntshav siab cawm nyob rau hauv cov neeg laus uas kuaj tau vasodilatory shock, npog cov kev kho mob subtypes xws li postoperative hypotension tom qab phais plawv thiab sepsis -induced distributive shock. Cov neeg mob no feem ntau tsis ua tiav cov ntshav siab ruaj khov rov qab los tom qab cov txheej txheem kev cuam tshuam nrog suav nrog kev kho cov kua dej txaus hauv cov hlab ntsha thiab kev niaj hnub ua ntej - cov tshuaj vasopressor, yog li xav tau vasopressin ntxiv rau kev txhawb nqa hemodynamic. Endogenously, vasopressin yog ib qho tseem ceeb polypeptide hormone lawm synthesized nyob rau hauv lub hypothalamus thiab tom qab khaws cia thiab tso tawm los ntawm lub posterior pituitary caj pas nyob rau hauv tib neeg lub cev. Ib qho ntawm nws txoj haujlwm canonical physiological lub hom phiaj rau lub raum tubular epithelial hlwb: los ntawm kev khi rau tshwj xeeb V2 receptors ntawm nephron tubules, nws txhim kho cov reabsorption ntawm cov dej dawb los ntawm thawj cov zis rov qab mus rau hauv lub cev, txo qis zis tso zis thiab ua kom lub cev muaj zog tshuav nyiaj li cas hauv lub cev lossis kev ntxhov siab.
- Dab tsi yog vesopressin siv rau hauv ICU?
Concomitant infusion ntawm vesopressin tuaj yeem siv rau hauv cov xwm txheej ntawm refractory septic shock kom ncav cuag lossis tswj lub hom phiaj ntawm cov hlab ntsha siab thiab / lossis txo qis catecholamine cov cai, uas tuaj yeem ua pov thawj tshwj xeeb rau cov neeg mob uas muaj mob arrhythmias lossis nce myocardial thov cuam tshuam nrog siab.
- Vim li cas vesopressin tsis siv lawm?
Kev tshem tawm ntawm vasopressin los ntawm kev kho mob algorithm yog tsim los ntawm cov kev tshawb fawb soj ntsuam zoo thiab cov ntaub ntawv txheeb cais. Cov kev tshawb fawb ntsig txog tau lees paub tias kev sib koom ua ke ntawm kev tswj hwm ntawm epinephrine ntxiv rau vasopressin tsis tuaj yeem xa cov txiaj ntsig kho mob ntxiv hauv cov txiaj ntsig kev kho mob thaum teem rau monotherapy siv epinephrine ib leeg; tsis muaj kev txhim kho nyob rau hauv cov ciaj sia taus, hemodynamic rov qab los yog lub cev perfusion tuaj yeem raug lees paub los ntawm dual - tshuaj noj. Txhawm rau txhim kho kev ua haujlwm ntawm cov tshuaj thaum muaj xwm txheej ceev, txo qis cov txheej txheem npaj tshuaj tsis tsim nyog, txo qhov kev pheej hmoo ntawm kev siv tshuaj tsis raug thiab ua kom yooj yim rau cov txheej txheem kho mob rau cov neeg ua haujlwm kho mob pem hauv ntej, vasopressin thaum kawg raug tshem tawm los ntawm cov npe tshuaj pom zoo.
Cim npe nrov: vasopressin 20 units, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom