Triptorelin Txhaj 3.75 Mg

Shaanxi BLOOM Tech Co., Ltd. yog ib qho ntawm feem kev manufacturers thiab lwm tus neeg ntawm triptorelin txhaj 3.75 mg nyob rau hauv Suav teb. Txais tos rau cov lag luam wholesale bulk zoo triptorelin txhaj 3.75 mg rau muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.

Triptorelin Txhaj 3.75 mg,Raws li cov tshuaj tiv thaiv kab mob endocrine meej meej, tau pom cov txiaj ntsig tseem ceeb hauv kev kho mob sib txawv. Nws lub luag haujlwm tseem ceeb tau cuam tshuam rau hauv ob qho kev qhia: cov txheej txheem tseem ceeb ntawm kev tswj hwm thiab cov txiaj ntsig kho mob ntawm inhibiting ntxov ovulation, thiab cov txheej txheem tseem ceeb thiab tus nqi ntawm inhibiting testosterone secretion.

Cov qub tuaj yeem muab qhov chaw ruaj khov thiab tswj tau follicular kev loj hlob ib puag ncig rau kev pabcuam kev ua me nyuam, ua kom cov txheej txheem kev ua haujlwm ntawm ovulation induction; Cov tom kawg tuaj yeem tsom mus rau kev mob qog noj ntshav prostate los ntawm kev txiav tawm cov tshuaj hormones dependence thiab ncua kev loj hlob ntawm qog nqaij hlav, ob qho tib si ntawm kev vam khom cov kev cai ntawm lub cev xeeb tub axis kom ua tiav kev nyab xeeb thiab muaj txiaj ntsig kev kho mob.

Cov Khoom Siv

triptorelin peptide

Triptorelin Txhaj

triptorelin ntsiav tshuaj

Triptorelin COA

Certificate of Analysis
Compound npe	Triptorelin
Qib	Pharmaceutical qib
CAS Nr.	57773-63-4
Ntau	30g
Ntim txheem	PE hnab + Al foil hnab
Chaw tsim tshuaj paus	Shaanxi BLOOM TECH Co., Ltd
Ntau No.	202501090066
MFG	Peb 9, 2026
EXP	Peb 8, 2029
Qauv
Yam khoom	Enterprise txheem	Kev txheeb xyuas qhov tshwm sim
Qhov tshwm sim	Dawb los yog yuav luag dawb hmoov	Ua raws
Cov ntsiab lus dej	Tsawg dua lossis sib npaug li 5.0%	0.54%
Poob rau ziab	Tsawg dua lossis sib npaug li 1.0%	0.42%
Hnyav Hlau	Pb Tsawg dua lossis sib npaug li 0.5ppm	N.D.
	Tsawg dua lossis sib npaug li 0.5ppm	N.D.
	Hg Tsawg dua lossis sib npaug li 0.5ppm	N.D.
	Cd Tsawg dua lossis sib npaug li 0.5ppm	N.D.
Purity (HPLC)	Ntau dua lossis sib npaug li 99.0%	99.98%
Ib qho impurity	<0.8%	0.52%
Tag nrho microbial suav	Tsawg dua lossis sib npaug li 750cfu / g	95
E. Coli	Tsawg dua lossis sib npaug li 2MPN / g	N.D.
Salmonella	N.D.	N.D.
Ethanol (los ntawm GC)	Tsawg dua lossis sib npaug li 5000ppm	500ppm ua
Cia	Khaws rau hauv qhov chaw kaw, tsaus, thiab qhuav hauv qab -20 degree

Cov txheej txheem tswj hwm tseem ceeb thiab cov nqi kho mob ntawm inhibiting ntxov ovulation

Hauv kev pabcuam kev ua menyuam yaus, cov ntsiab lus tseem ceeb ntawm ovulation induction theem yog kom tau txais ntau yam siab -cov follicles zoo uas loj hlob zoo synchronously, thaum qhov tshwm sim ntawm ovulation ntxov yuav ua rau lub hom phiaj no ncaj qha thiab coj ntau yam teeb meem rau txoj kev kho mob.

Triptolide ua tau zoo inhibits ovulation ntxov ntxov los ntawm kev sib npaug ntawm txoj kev ua me nyuam, uas tuaj yeem txheeb xyuas los ntawm ob qhov loj me:

(I) Thaiv lub ncov ntxov ntxov ntawm luteinizing hormone kom tsis txhob ntxov ntxov rupture ntawm follicles

Qhov zoo li qub ntawm hypothalamic pituitary gonadal axis yog lub hauv paus ntawm kev tswj ovulation. Nyob rau hauv ib txwm physiological tej yam kev mob, lub ncov ntawm luteinizing hormone tshwm synchronously nrog follicle maturation. Txawm li cas los xij, thaum pab kev ua me nyuam ovulation induction, yog tias cov tshuaj hormones nce ntxov dhau thiab tsim qhov txawv txav, nws yuav ua rau ntxov ntxov rupture thiab tawm ntawm follicles, ua rau poob ntawm cov follicles tsis paub qab hau.

Triptolide tuaj yeem maj mam tswj cov kev ua haujlwm ntawm lub qog pituitary, inhibit qhov kev tso tawm ntxov ntawm luteinizing hormone, tshem tawm cov tseem ceeb ua rau cov follicles ntxov ntxov, ua kom muaj kev loj hlob ntawm cov follicles kom loj hlob nyob rau hauv lub preset lub sij hawm qhov rais, thiab tsis txhob follicle pov tseg thiab kev kho mob cuam tshuam los ntawm ntxov ovulation.

(II) Tswj lub synchronicity ntawm follicular txoj kev loj hlob thiab txo qhov kev pheej hmoo ntawm ovulation teeb meem

Qhov tshwm sim ntawm ovulation ntxov ntxov yog feem ntau nrog asynchronous follicular txoj kev loj hlob, qhov twg ib co follicles paub tab thiab raug ntiab tawm ntxov ntxov, thaum lwm tus neeg tsim rhythmically, thaum kawg ua rau ib tug tsis txaus cov follicles.

Triptorelin txhaj tshuaj 3.75 mgstabilizes cov cai tswj kev taw qhia ntawm kev ua me nyuam axis.Kev zam lub imbalance ntawm follicular kev loj hlob atherosclerosis tshwm sim los ntawm cov tshuaj hormone fluctuations, txhawb synchronous loj hlob thiab maturation ntawm ntau follicles, txo qhov tshwm sim ntawm ovulation ntxov ntxov ovulation los ntawm lub hauv paus, thiab muab txaus thiab siab -zoo follicle reserves.

Cov ntaub ntawv Source:

Zheng Li, Li Chang. Daim ntawv thov ntawm Triptolide Ua ke nrog Androgens nyob rau hauv sib sib zog nqus Inhibition ntawm Testosterone nyob rau hauv Advanced Prostate Cancer [J]. Cancer Progression, 2022, 20 (8): 781-784
Fizazi K, Sternberg C N. Kev hloov tshiab ntawm Triptorelin: Tam sim no xav txog Androgen Deprivation Therapy rau Prostate Cancer[J]. Tshuaj nyob rau hauv R&D, 2016, 16(3): 247-256.

Wu Bin, Wang Jian. Cov nyhuv stabilizing thiab kev soj ntsuam tseem ceeb ntawm triptorelin ntawm testosterone hloov pauv hauv kev mob qog nqaij hlav prostate [J]. Suav Journal of Clinical Pharmacology, 2021, 37 (12): 1523-1526

Cov txheej txheem tswj hwm tseem ceeb thiab tus nqi ntawm inhibiting testosterone secretion

Thaum lub sij hawm kev loj hlob ntawm kev mob qog nqaij hlav prostate, qhov txawv txav ntawm testosterone yog qhov tseem ceeb ntawm kev tsav tsheb tom qab kev tswj tsis tau ntawm cov qog hlwb thiab kev sib kis tas mus li ntawm qhov txhab. Kev nce qib ntawm testosterone tsis tu ncua yuav ua rau kom cov qog ua kom tsis zoo, tsis yog tsuas yog ua rau ntau qhov tsis xis nyob hauv tus neeg mob lub cev, tab sis kuj tseem ua rau muaj kev nyuaj siab ntxiv, ua rau muaj kev cuam tshuam ntau dua rau kev kho mob. Rau cov neeg mob uas muaj mob qog noj ntshav prostate, testosterone zoo li "cov khoom noj khoom haus" rau cov qog loj hlob.

Ua rau kev nthuav dav ntawm qhov txhab thiab qhov txuas ntxiv ntawm qhov infiltration ntau yam, uas ua rau muaj kev tsis xis nyob hauv lub cev ntau dua thiab tseem cuam tshuam rau tus neeg mob lub neej kev nyab xeeb.Nrog nws cov kev tswj xyuas meej,triptorelin txhaj tshuaj 3.75 mgua rau txoj kev sib kis ntawm cov kab mob hauv lub cev, ua tiav kev tswj hwm kev tshawb fawb ntawm testosterone secretion los ntawm kev ntsuas cov cim tseem ceeb.Nws txiav tawm cov tshuaj hormone txhawb nqa rau cov qog loj hlob los ntawm cov hauv paus hniav, inhibits lub hauv paus ua rau cov qog deterioration, thiab nteg lub hauv paus ruaj khov rau cov qog nqaij hlav tom ntej ntawm kev sib txuas ntawm testosterone.

 Qhov chaw ntawm cov ntaub ntawv ntawm ntu no:

Lundströ m EA, Rencken RK, van Wyk J H. Triptorelin 6-hloov formulation nyob rau hauv kev tswj cov neeg mob uas muaj mob qog noj ntshav hauv zos thiab metastatic prostate: qhib-label, tsis sib piv, multicentre, theem Ⅲ kawm[J]. Clinical Drug Investigation, 2009, 29(11): 757-765.
Tuam Tshoj Medical Association Urology ceg. Suav Cov Kws Tshaj Lij Pom Zoo rau Kev Tswj Xyuas Testosterone hauv Prostate Cancer (2021 Edition) [J]. Suav Journal of Urology, 2021, 42 (5): 321-328

Kev tsim thiab kev tso tawm ntawm testosterone tsis tshwm sim hauv kev sib cais, tab sis cia siab rau kev tswj hwm kev tswj hwm thiab cov teeb liab hloov pauv ntawm lub cev kev loj hlob axis, tsim kom muaj kev tswj hwm lub cev tag nrho.
Vim muaj kev cuam tshuam ntawm kev mob qog noj ntshav prostate siab heev, kev tswj hwm kev ua haujlwm ntawm lub cev xeeb tub yog cuam tshuam thiab tsis sib npaug, thiab cov teeb meem sib kis tau txawv txav, ua rau testosterone secretion deb tshaj li ib txwm muaj, tsim qhov txawv txav, thiab tsis tu ncua muab lub zog loj hlob rau cov qog hlwb.Triptolide tso tseg cov kev cuam tshuam ntawm kev ua haujlwm tsis pub lwm tus paub. pituitary caj pas nyob rau hauv ib tug maj mam thiab meej,

Ua tau zoo inhibiting qhov tso tawm ntau dhau ntawm gonadotropin- cov cim qhia txog, txiav tawm txoj hauv kev sib kis tsis zoo los ntawm qhov chaw ntawm testosterone ntau lawm, maj mam txo tag nrho cov synthesis thiab tso tawm ntawm testosterone, thiab maj mam tswj cov qib testosterone hauv lub cev mus rau qhov tsim nyog ntau yam uas ua tau raws li kev xav tau ntawm kev mob qog noj ntshav prostate.

Nws tshem tawm cov tseem ceeb cov tshuaj hormones ua rau cov qog nqaij hlav los ntawm cov hauv paus hniav, tsim cov kev mob zoo rau kev tswj cov qog tom qab.Stabilize cov tshuaj hormone secretion atherosclerosis thiab zam cov qog stimulation los ntawm testosterone fluctuations.

Testosterone theem ntawm cov neeg mob uas muaj mob cancer prostate tsis tsuas yog raug kev txom nyem los ntawm kev tso tawm ntau dhau, tab sis kuj feem ntau hloov mus ua nruj.

Lub xeev cov tshuaj hormones tsis ruaj khov no rov ua rau muaj kev ua haujlwm loj ntawm cov qog hlwb, ua rau muaj kev cuam tshuam sai ntawm cov qog nqaij hlav.Tam sim no, nws tuaj yeem ua rau muaj ntau yam tsis xis nyob hauv tus neeg mob lub cev, xws li kev xav hloov pauv, lub cev tsis muaj zog, thiab qhov mob zais hauv zos.
Triptolide tsis tsuas yog ua haujlwm zoo inhibits testosterone secretion thiab txo tag nrho cov tshuaj hormones, tab sis kuj tswj cov kev tswj hwm kev sib raug zoo ntawm lub cev lub cev xeeb tub.

Ua kom muaj kev ruaj ntseg ntawm cov tshuaj hormones hauv lub cev, zam kev hloov pauv loj hauv qib testosterone, txo qhov kev tawm tsam ntawm cov qog hlwb los ntawm cov tshuaj hormone hloov pauv, thiab tsim kom muaj kev ruaj khov thiab tsim nyog rau kev tswj cov qog tom qab. Nyob rau tib lub sijhawm, lub xeev cov tshuaj hormones ruaj khov no tuaj yeem txo ntau yam tsis xis nyob ntawm lub cev los ntawm cov tshuaj hormones, txo cov neeg mob lub cev lub cev, thiab txhim kho lawv lub cev kev nplij siab thiab kev cuam tshuam kev ua raws cai.

Qhov chaw ntawm cov ntaub ntawv:

Breul S, Schmid JP, Haas G P. Kev ua tau zoo ntawm Testosterone Kev Txhaum Cai nrog Kev Tiv Thaiv -Tshuaj Triptorelin hauv Advanced Prostate Cancer[J]. BJU International, 2016, 118(4): 586-592.

Chen Gang, Liu Hao. Molecular mechanism kawm txog kev tswj ntawm kev ua me nyuam axis thiab inhibition ntawm testosterone secretion los ntawm triptorelin [J]. Suav Pharmacological Bulletin, 2022, 38 (3): 421-426
Kim WS, Park JC, Lee S E. Kev ua tau zoo ntawm peb qhov sib txawv luteinizing hormone- tso cov tshuaj hormone agonists hauv cov tshuaj castration ntawm cov neeg mob qog nqaij hlav cancer: Goserelin piv rau triptorelin piv rau leuprolide[J]. Kev Tshawb Fawb thiab Kev Kho Mob Urology, 2019, 60(4): 244-250.

Cov ntaub ntawv

Zhou Ming, Huang Jian. Kev soj ntsuam kev ua tau zoo ntawm kev ua haujlwm ntev - ua yeeb yam triptorelin hauv kev txhawb nqa testosterone hauv kev mob qog noj ntshav siab [J]. Phau ntawv Journal of Modern Urology, 2020, 25 (6): 521-524
Cornford P, Jefferson K, Cole O. Cov txiaj ntsig ntawm kev pib lossis hloov mus rau 6 -ib hlis triptorelin formulation rau tus neeg mob qog noj ntshav prostate- kev sib cuam tshuam kev noj qab haus huv thiab kev siv hauv tsev kho mob: ib qho tiag tiag - ntiaj teb, rov qab los, tsis yog - txoj kev tshawb fawb [J]. Oncology thiab Therapy, 2018, 6(2): 173-187.
Shore ND, Shore D M. Triptorelin embonate: 6-hli formulation for prostate cancer[J]. Kws muaj txuj tswv yim ntawm Pharmacotherapy, 2010, 11(15): 2569-2578.

Triptorelin txhaj tshuaj 3.75 mgyog siv los kho mob qog noj ntshav prostate. Nws yog ib qho tshuaj hormones uas zoo ib yam li ib txwm tso tawm los ntawm lub qog hypothalamus hauv lub hlwb. Thaum muab rau cov txiv neej tsis tu ncua, nws txo qis testosterone qib uas pab kho mob qog noj ntshav prostate.

Kev txhaj tshuaj triptorelin ntev npaum li cas?

Muaj 2 hom triptorelin. Peb muab raws li kev txhaj tshuaj rau hauv cov leeg (intramuscular). Nws tuaj yeem muab tau txhua 28 hnub (4 lub lis piam), lossis ntev dua - txhaj tshuaj txhua 3 lossis 6 lub hlis.

txhaj tshuaj nyob qhov twg?

Koj feem ntau muaj nws li kev txhaj tshuaj rau hauv cov leeg nqaij (intramuscular), hauv koj lub pob tw lossis sab ncej puab. Yog tias koj muaj ib hom hu ua Gonapeptyl Depot, koj tuaj yeem txhaj tshuaj hauv qab ntawm daim tawv nqaij (subcutaneous txhaj) rau hauv koj lub plab (mob plab), ncej puab lossis sab caj npab.

Cim npe nrov: triptorelin txhaj tshuaj 3.75 mg, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom