Vermox creamyog cov organic sib xyaw nrog cov tshuaj noj tshuaj noj tshuaj c16h13n3o3n3o3 thiab ua rau muaj kev cuam tshuam loj heev thiab cuam tshuam nrog kev tua cov qe ntawm cov piam thaj los ntawm Nematodes, ua rau glycogen depletion thiab txo qhov tsim ntawm Adenosine Trips thiab nws tsis muaj peev xwm ua kom muaj kev sib cav sib ceg, tab sis nws tsis muaj peev xwm ua rau kev sib sau ua ke, ua rau kev sib sau ua ke ntawm cov khoom zais zais hauv Golgi Apparatus, tshwm sim hauv kev thauj khoom, cytoplasmic dissibute thiab kev nqus, ua kom haum cell degreration, thiab kab tuag {}
Cov ntaub ntawv ntxiv ntawm kev sib txuas lus:
Peb Cov Khoom
Toltrazuril +. coa
Cov ntxaij tretict ntawm cov mob hnyuv pauj kab mob:
Mebendazole yog ib qho tshuaj uas nyiam kho rau kev kho mob plab hnyuv cab, thiab cov kab mob kis las, thiab cov kab mob sib txawv ntawm cov kab mob thiab muaj kab mob thiab hnub nyoog ntawm lub tus neeg mob .} Piv txwv, thaum kho cov kab mob kab mob thiab tus kab mob kab mob, cov neeg laus thiab cov menyuam yaus dua 2 xyoos ib txwm siv 200MG conally; Thaum kho tus kab mob heroworm thiab tus kab mob dab qhuas, 200mg yuav tsum tau noj ib zaug, ob zaug ib hnub, rau peb hnub sib law.
Tretment ntawm cov kab mob parasitic tsis pub dhau cov ntaub so ntswg:
Ntxiv nrog rau cov mob hnyuv pauj, metronidazole kuj tseem siv tau los kho qee tus mobileitic tus kab mob, xws li cov cybal cyascosis, thiab Trichomoniasis.
Rau cov mob no, cov tshuaj thiab cov chav kawm ntev dua los siv tshuaj rau cov tshuaj uas muaj txiaj ntsig, nws yuav tsum tau siv cov tshuaj uas muaj txiaj ntsig, nws yuav tsum tau siv cov tshuaj yub
Kev Kho Mob:
Hauv qee kis, metronidazole tuaj yeem siv ua ke nrog lwm cov tshuaj tiv thaiv antiparasitel los txhim kho cov chaw ua haujlwm {}} Txawm li cas los xij, thaum siv cov kev kho mob ua ke, kev saib xyuas rau kev sib cuam tshuam ntawm cov tshuaj thiab tsub zuj zuj ntawm kev cuam tshuam tsis zoo .
Vermox cream, tseem hu ua benzimidazole, yog ib qho synthesial benzimidazole compound {}} Koj cov tshuaj tua kab mob tseem ceeb teasconazole tus neeg ua si tseem ceeb hauv cov kab mob parasitic cov kab mob {}}}}}}} ntawv thov, thiab kev nyab xeeb.
Chaw muag khoom
Mechanism ntawm Antiparasitic Action:
Mebendazole tiav lub hom phiaj ntawm kev tua cab los ntawm kev siv cov roj ntsha uas tsis sib haum, ua rau lawv cov txheej txheem sib xyaw ua ke ua rau cov txheej txheem ntawm Glycogen hauv Parasite, txo qis tsim ntawm Adenosine Triphosphate (ATP), tsis muaj txiaj ntsig ntawm cov neeg ua haujlwm ntawm cov kab mob ntshav, thiab cov kev tuag thaum kawg, yog li nws muaj kev nyab xeeb .
Soj ntsuam ntawm kev hloov chaw uas tau pom tias tom qab metronidazole, microlotlasmic nyob rau hauv lub puab tsaig tsis pub lwm tus paub, thiab cov kab mob plab zom mov, thiab cov kab mob hnyuv luam tawm, thiab cov kab mob hnyuv luam tawm, thiab cov kab mob hnyuv luam tawm, thiab cov kab mob hnyuv luam tawm, thiab cov kab mob hnyuv tau tshaj tawm metronidazole ntawm parasites .
Txhim Kho Spectrum Anti Parasitic Spectrum:
Mebendazole muaj dav-specarasitic kev ua ub no thiab muaj cov kev kho mob zoo li cov kab mob siab, metronidazole, wookworms, cov rauv taws, sib xyaw, echinocccos, thiab Trichomoniasis . Txuas ntxiv, ua rau kev txhim kho ntawm cov qe kab, yog li txo qhov kis ntawm parasites.
Rau cov roundwiavs thiab dab tsi, tebenmonazole tsis tsuas yog muaj cov txiaj ntsig ntawm cov neeg laus, tab sis kuj tau ua kom muaj sia nyob rau hauv cov khoom siv roj ntsha cuam tshuam nrog lawv cov kev ua haujlwm metabolic .
Pharmaconinetics
Nqus thiab faib khoom:
Ketoconazole nqus tau tsawg dua tom qab kev tswj hwm qhov ncauj, nrog rau kev nqus cov tshuaj thiab muaj li ntawm 95% yog li ntawm 95% lub cev .
Kev faib tawm ntawm metronidazole nyob rau hauv lub cev muaj cov nqaij mos thiab tuaj yeem nkag rau hauv lub cev nqaij hlav me me los ntawm kev sib kis mob ntawm lub plab me me, yog li cov poj niam cev xeeb tub, yog li cov poj niam cev xeeb tub yuav tsum siv nws nrog Ceev faj .
Metabolism thiab excretion:
Mekendazole tau sai metabolized nyob rau hauv daim siab, feem ntau hloov cov zis ntawm cov zis thiab cov zis me me hauv lawv daim ntawv qub los yog cov metabolites tom qab decarboxylation tsis pub dhau24-48 cov sij hawm, nrog ib nrab-lub neej ntawm {{}}. Txawm li cas los xij, ib nrab-lub neej ntawm metres rau 35 teev .
Vermox creamyog qhov dav-spectrum antiparasitic tshuaj tiv thaiv cov tshuaj uas cuam tshuam nrog lwm cov kev sib txuam, nws yuav cuam tshuam nrog nws cov kev pheej hmoo ntawm kev siv tshuaj, nws tuaj yeem cuam tshuam nrog nws cov kev xav tau cov ncauj lus kom ntxaws ntawm cov tshuaj muaj kev sib cuam tshuam tshuaj yeeb:
Kev sib cuam tshuam yeeb tshuaj feem ntau yog muaj ob qho kev cuam tshuam, kev nqus, cov kev sib cuam tshuam ntawm cov tshuaj ntawm Mebendazole tuaj yeem tshwm sim los ntawm cov txheej txheem hauv qab no:
Metabolic enzyme inhibition lossis induction:
Mebendazole metabolism may be affected by other drugs' effects on liver microsomal enzymes (such as CYP450 enzyme system), thereby altering its blood drug concentration and efficacy.
Qhov cuam tshuam ntawm cov tshuaj thauj:
Qee yam tshuaj yuav cuam tshuam cov tshuaj thauj hauv plab hnyuv epithelium, yog li cuam tshuam rau kev nqus thiab faib ntawm mebendazole .
Photorcynamic synergy lossis antagonism:
Mebendazole yuav muaj synergictorial lossis kev tsis sib haum xeeb ntawm lwm cov tshuaj nyob rau lwm cov tshuaj nyob rau hauv cov tshuaj ntawm cov tshuaj ntawm cov tshuaj muag, cuam tshuam rau kev kho cov nyhuv kho mob {}}
Mob siab microsomal enzyme inhibitors:
Cimetidine: CIMETIDINE tuaj yeem inhibit lier metabomal kev ua si, thiab tuaj yeem ua kom muaj kev pheej hmoo ntau ntxiv {}}
Lwm cov enzyme inhibitors, xws li erythromycin, xws li qee yam tshuaj tiv thaiv kab mob ntawm Mebendazience (Ketoconazole)
Mob siab microsomal enzyme inducer:
Phenytoin sodium: phenytoin sodium tuaj yeem ua kom lub siab tawv, txo cov tshuaj metabolal me me, thiab tej zaum yuav ua kom muaj zog kho cov tshuaj, thiab tej zaum yuav ua kom muaj zog kho mob.
Carbamazepine: carbamazinepine kuj tseem muaj lub siab tawv me ntawm cov nyhuv ntawm Mebendazole .
Rifampicin: Rifampicin yog qhov yuam kev me me ntawm daim siab micrendzymes, thiab thaum siv kev ua qoob loo nrog kev ua kom cov ntshav siab, nws yuav cuam tshuam ntau .
Lwm cov tshuaj uas yuav cuam tshuam rau MineDazole nqus:
Antacids: qee cov tshuaj tiv thaiv tuaj yeem hloov kho tus nqi sam thiaj li muaj lub plab zom mov, cuam tshuam kev sib cais thiab kev nqus ntawm mebendazole momendazole {}}
Adsorbents: Adsorbents xws li ua kom zoo dua cov roj carbon yuav
Cov tshuaj uas yuav cuam tshuam nrog lwm tus hauv chaw muag tshuaj:
Lwm cov tshuaj tiv thaiv antiparasitic: thaum siv ua ke nrog Mebendazole, lawv yuav txhim kho kev pheej hmoo uas muaj kev pheej hmoo uas .
Cov tshuaj noj nrog Central inhibitos cuam tshuam, xws li cov tshuaj sedatives, antihistamines, uas yog ua kom muaj kev phom sij thiab kiv taub hau zuj zus thiab kiv taub}
Weakened Theactutic tsis muaj zog:
Thaum Mebendazole ua ke nrog lub siab micromomal enzyme injectates, xws li kev siv ntshav ua kom muaj zog, thiab cov tshuaj tiv thaiv cov nyhuv kom tsis muaj zog.
Cov xwm txheej no yog qhov tshwj xeeb tshaj yog qhov xav tau kev kis phem lossis cov kab mob kis hnyav, uas yuav cuam tshuam rau tus neeg mob rov qab los.
Nce kev phiv tshuaj:
Thaum Mebendazole ua ke nrog daim siab micromomal enzyme inhibitors xws li Cimetidine thiab ntshav tshuaj muaj kev pheej hmoo nce, uas tuaj yeem ua rau muaj kev pheej hmoo ntawm cov kev pheej hmoo uas .
Cov kev tshwm sim uas muaj kev sib raug zoo xws li xeev plab, mob plab, raws plab, raws plab, raws plab, raws plab, raws plab xws li ua kev ua xua thiab ua kev ua xua li {}}
Hauv qee qhov tsawg zaus, kev sib haum xeeb heev (xws li exfoliative dermatitis, qhov kev ua kom mob siab) lossis lub raum tsis sib haum yuav tshwm sim .
Synergistic lossis antagonistic lossis antagonistic cuam tshuam hauv chaw muag tshuaj:
Thaum siv ua ke nrog lwm cov tshuaj antiparasitic,Vermox creamtuaj yeem txhim kho kev ua tau zoo vim vim muaj kev cuam tshuam cov khoom muag, tab sis nws kuj tseem tuaj yeem ua rau muaj kev pheej hmoo pheej hmoo kev pheej hmoo {}}
Thaum siv kev sib xyaw ua ke nrog cov yeeb tshuaj nrog Central txwv tsis pub muaj kev phom sij xws li kev txaus ntshai thiab kiv taub hau thiab ua haujlwm muaj peev xwm {}}
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