Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm ethyl hydrogen malonate cas 1071-46-1 nyob rau hauv Suav teb. Txais tos rau kev lag luam wholesale bulk zoo ethyl hydrogen malonate cas 1071-46-1 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Ethyl Hydrogen Malonate, tseem hu ua succinic monobutyl ester, ingeniously integrates carboxylic acid thiab ester functional pawg nyob rau hauv nws cov qauv molecular. Cov cuab yeej "amphiphilic" no ua rau nws deb tshaj li qhov yooj yim tshuaj nruab nrab. Hauv kev txiav-ntug ntawm supramolecular chemistry thiab cov ntaub ntawv kev tshawb fawb, nws ua haujlwm raws li lub zog sib dhos zoo nkauj: nws pawg carboxyl tuaj yeem ua lub zog muaj zog hydrogen nyiaj pub dawb, ua kom ruaj khov ob- qhov sib txuas nrog ntau yam nitrogen- muaj heterocycles (xws li pyridines), triazine.
Thaum pawg ester ua raws li lub pob khawm hloov tau, thiab nws cov carbamido units tuaj yeem txhim kho interlayer stacking los ntawm tsis muaj zog van der Waals rog. Qhov no multi-theem molecular paub muaj peev xwm ua rau nws ua rau nws tus kheej - sib sau ua ke ntawm cov organic me me molecules ntawm chav tsev kub los tsim cov ntaub ntawv crystalline nrog nanopores li niaj zaus. Cov ntaub ntawv no qhia tau hais tias muaj peev xwm tshwj xeeb rau kev xaiv adsorption ntawm cov qhua molecules los yog tsis yog -cov khoom siv roj ntsha organic catalyst, muab lub ntsiab lus tshiab tshaj li cov hlau ib txwm siv- cov txheej txheem organic rau kev tsim kho ntawm "ntsuab" cov ntaub ntawv ntxeem tau.
Cov ntaub ntawv ntxiv ntawm chemical compound:
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Tshuaj Formula |
C5H8O4 |
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Exact Mass |
132.04 |
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Molecular Luj |
132.12 |
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m/z |
132.04 (100.0%), 133.05 (5.4%) |
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Elemental Analysis |
C, 45.46; H, 6.10; O, 48.44 |
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Melting point |
-13℃(lit.) |
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Boiling point |
106.5℃/ 3 mmHg (lit.) |
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Qhov ntom |
1.119 g / mL ntawm 25℃(lit.) |
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Ethyl hydrogen malonateyog ib qho tseem ceeb organic compound nrog cov tshuaj formula C5H8O4 thiab CAS naj npawb 1071-46-1. Nws muaj qee yam acidity thiab nyuaj rau yaj hauv dej, tab sis tuaj yeem ua rau miscible nrog cov kuab tshuaj organic. Vim nws cov qauv tshuaj lom neeg tshwj xeeb thiab cov khoom siv, nws muaj ntau yam kev siv hauv ntau qhov chaw. Cov hauv qab no yog cov lus piav qhia ntxaws txog nws lub hom phiaj:
Monoethyl malonate yog ib tug derivative ntawm malonic acid esters, uas muaj ib tug ester chav tsev thiab ib tug carboxyl qauv nyob rau hauv nws cov qauv, muab nws ntau yam tshuaj hloov dua siab tshiab zog. Hauv cov organic synthesis, monoethyl malonate feem ntau yog siv los ua ib qho tseem ceeb nruab nrab thiab koom nrog ntau yam tshuaj lom neeg. Monoethyl malonate tuaj yeem txuas ntxiv mus rau esterification cov tshuaj tiv thaiv nrog ethanol nyob rau hauv qhov kev txiav txim ntawm cov kua qaub los yog hauv paus, ua rau diethyl malonate. Cov tshuaj tiv thaiv no tseem ceeb heev hauv cov organic synthesis, vim tias diethyl malonate kuj yog ib qho tseem ceeb ntawm cov organic sib txuas uas siv dav hauv cov teb xws li tshuaj, tshuaj tua kab, dyes, thiab lwm yam.
Cov carboxyl units hauv Monoethyl malonate qauv tuaj yeem hloov mus rau hauv cov carboxylic acid anions nyob rau hauv alkaline tej yam kev mob xws li potassium hydroxide. Qhov tsis zoo ion no muaj zog nucleophilicity thiab tuaj yeem koom nrog ntau yam kev hloov pauv nucleophilic, yog li nthuav cov tshuaj tiv thaiv kab mob ntawm monoethyl malonate. Piv txwv li, nws tuaj yeem hloov pauv cov tshuaj tiv thaiv nrog halogenated hydrocarbons, cawv, thiab lwm yam sib txuas los tsim cov organic sib txuas nrog cov qauv sib txawv thiab kev ua haujlwm. Monoethyl malonate kuj tuaj yeem txo qis cov tshuaj tiv thaiv nyob rau hauv qhov kev txiav txim ntawm qee cov tshuaj txo qis, tsim cov cawv sib txuas. Cov tshuaj tiv thaiv no kuj muaj qee yam kev siv hauv cov organic synthesis.
Daim ntawv thov ntawm Monoethyl Malonate nyob rau hauv kev lag luam teb yog feem ntau xav txog nyob rau hauv nws siv raws li ib tug tshuaj raw khoom rau synthesizing ntau yam biologically active tebchaw. Monoethyl malate tuaj yeem hloov mus rau hauv cov tshuaj molecules nrog cov kev ua haujlwm pharmacological tshwj xeeb los ntawm cov tshuaj tiv thaiv kab mob. Piv txwv li, nws tuaj yeem ua ke nrog cov tshuaj intermediates uas muaj cov amino lossis hydroxyl pawg los ntawm esterification, amidation, thiab lwm yam kev cuam tshuam los tsim cov tshuaj uas muaj cov tshuaj pharmacological tshwj xeeb. Cov tshuaj no ua lub luag haujlwm tseem ceeb hauv kev kho ntau yam kab mob. Monoethyl malate kuj tseem siv tau los ua cov tshuaj nruab nrab los koom nrog hauv kev sib txuas ntawm cov tshuaj molecules complex.
Hauv cov txheej txheem ntawm kev txhim kho tshuaj, cov kws tshawb fawb feem ntau yuav tsum tau siv cov tshuaj organic xws li Monoethyl Malonate los tsim cov tshuaj molecules nrog cov qauv tshwj xeeb thiab kev ua haujlwm los ntawm ntau yam - cov tshuaj tiv thaiv kab mob.
Monoethyl malate kuj muaj qee yam kev siv hauv kev sib txuas ntawm surfactants. Surfactants yog ib hom kev sib xyaw nrog cov dej tshwj xeeb uas tuaj yeem tsim cov yeeb yaj kiab nyias ntawm qhov chaw lossis kev sib tshuam ntawm kev daws teeb meem, yog li hloov kho lub cev thiab tshuaj lom neeg ntawm cov tshuaj. Monoethyl malate tuaj yeem hnov mob nrog lwm cov tebchaw los tsim cov tshuaj tiv thaiv saum npoo av, uas muaj ntau yam kev siv hauv detergents, emulsifiers, dispersants, thiab lwm yam.
Nyob rau hauv xyoo tas los no, monoethyl malonate tau pom los txhawb kev loj hlob ntawm cov nroj tsuag, txhim kho cov av nitrogen metabolism, ua kom cov av muaj nitrogen, txhim kho cov txiv hmab txiv ntoo zoo, txhawb cov nroj tsuag nqus nitrogen, phosphorus, thiab potassium, thiab optimize cov nroj tsuag physiological thiab biochemical enzyme systems. Cov kev tshawb pom no muab cov tswv yim tshiab rau kev siv cov monoethyl malonate hauv kev ua liaj ua teb. Monoethyl malonate tuaj yeem txhawb kev loj hlob thiab kev loj hlob ntawm cov nroj tsuag los ntawm kev tswj cov txheej txheem physiological thiab biochemical hauv cov nroj tsuag lub cev.
Piv txwv li, nws tuaj yeem txhim kho kev ua haujlwm ntawm photosynthesis hauv cov nroj tsuag, nce cov ntsiab lus ntawm chlorophyll, thiab yog li txhawb kev loj hlob ntawm cov nroj tsuag. Monoethyl malonate tuaj yeem txhawb nqa cov txheej txheem nitrogen hauv cov av thiab nce cov ntsiab lus nitrogen hauv av. Qhov no pab txhim kho av ib puag ncig, txhim kho av fertility, thiab nce qoob loo. Kev tshawb fawb tau pom tias monoethyl malonate tuaj yeem txhim kho cov txiv hmab txiv ntoo zoo. Piv txwv li, nws tuaj yeem ua rau cov ntsiab lus qab zib, xim, thiab saj ntawm cov txiv hmab txiv ntoo, ua rau nws qab thiab qab heev.
Ethyl Hydrogen Malonate, raws li ib qho tseem ceeb organic synthesis intermediate thiab tshuaj chemical raw khoom, tau qhia dav daim ntawv thov kev cia siab nyob rau hauv lub chemical kev lag luam, tshuaj manufacturing thiab lwm yam teb nyob rau hauv xyoo tas los. Cov hauv qab no yog cov lus piav qhia ntxaws txog nws txoj kev loj hlob zeem muag:
Kev ua lag luam xav tau kev txheeb xyuas
Kev lag luam thoob ntiaj teb xav tau kev loj hlob
Nrog rau kev txhim kho txuas ntxiv ntawm kev lag luam tshuaj thiab tshuaj lag luam thoob ntiaj teb, qhov kev thov rau cov organic synthesis intermediates thiab cov tshuaj chemical raw cov ntaub ntawv yog tas li nce. Raws li ib qho tseem ceeb organic synthesis intermediate thiab tshuaj chemical raw khoom, kev lag luam thov rau monoethyl malonate yuav loj hlob ntxiv. Tshwj xeeb tshaj yog nyob rau hauv cov teb chaws lag luam tawm tshiab, nrog rau kev ua kom muaj kev lag luam thiab kev txhim kho tib neeg txoj kev ua neej nyob, qhov kev thov rau siab - kawg tshuaj xws li monoethyl malonate yuav ua rau muaj zog dua.
Kev lag luam hauv tsev muaj peev xwm loj heev
Raws li ib qho ntawm cov neeg siv khoom siv tshuaj ntau tshaj plaws hauv ntiaj teb, Tuam Tshoj muaj peev xwm loj heev rau kev thov rau cov tshuaj siab - kawg xws li monoethyl malonate. Nyob rau hauv xyoo tas los no, Suav tsoom fwv tau txuas qhov tseem ceeb rau txoj kev loj hlob ntawm cov tshuaj thiab tshuaj industries, thiab tau qhia ib tug series ntawm txoj cai ntsuas los txhawb txoj kev loj hlob ntawm cov kev lag luam muaj feem xyuam. Qhov no yuav muab kev txhawb zog rau kev lag luam kev xav tau ntawm siab - cov tshuaj lom neeg xws li monoethyl malonate.
Expansion ntawm downstream daim ntawv thov cheeb tsam
Nrog rau kev nce qib ntawm thev naus laus zis thiab kev txhim kho ntawm kev lag luam, cov ntawv thov hauv qab ntawm monoethyl malonate tau nthuav dav tas li. Piv txwv li, hauv kev ua haujlwm ntawm lub zog tshiab, cov khoom siv tshiab, thiab kev tiv thaiv ib puag ncig, monoethyl malonate tuaj yeem siv los ua cov khoom tseem ceeb lossis cov khoom ntxiv. Qhov no yuav coj cov ntsiab lus loj hlob tshiab rau kev lag luam xav tau rau monoethyl malonate.
Technology Trend Analysis
Kev txhim kho txheej txheem ntau lawm
Tam sim no, cov txheej txheem tsim khoom ntawm monoethyl malonate feem ntau suav nrog cov tshuaj tiv thaiv hydrolysis ntawm diethyl malonate thiab esterification cov tshuaj tiv thaiv ntawm malonic acid nrog ethanol. Txhawm rau txhim kho kev tsim khoom thiab cov khoom lag luam zoo, cov tuam txhab lag luam thiab cov chaw tshawb fawb tseem niaj hnub tshawb nrhiav cov txheej txheem tsim khoom tshiab thiab cov txheej txheem catalyst. Piv txwv li, los ntawm kev txhim kho cov tshuaj tiv thaiv thiab optimizing catalyst kev ua tau zoo, cov tawm los thiab purity ntawm monoethyl malonate tuaj yeem nce ntxiv, thiab cov nqi tsim khoom tuaj yeem txo.
Environmental Protection thiab Sustainable Development
Nrog rau kev paub thoob ntiaj teb kev paub txog kev tiv thaiv ib puag ncig, kev tsim khoom thiab kev siv ntawm monoethyl malonate tseem yuav tau them nyiaj ntau rau kev tiv thaiv ib puag ncig thiab kev txhim kho kom ruaj khov. Cov tuam txhab lag luam thiab cov chaw tshawb fawb tau nquag tsim cov txheej txheem tsim khoom ntsuab thiab ib puag ncig tus phooj ywg thiab cov thev naus laus zis los txo cov pa phem thiab kev puas tsuaj rau ib puag ncig. Nyob rau tib lub sijhawm, lawv tseem ua haujlwm hnyav los txhawb cov kev siv ib puag ncig zoo ntawm monoethyl malonate, xws li kev siv cov nroj tsuag kev loj hlob, cov khoom siv biodegradable, thiab lwm yam.
Kev txawj ntse thiab automation
Nrog kev txhim kho txuas ntxiv ntawm kev txawj ntse thiab kev siv tshuab thev naus laus zis, cov txheej txheem tsim khoom ntawm monoethyl malonate yuav maj mam ua tiav kev txawj ntse thiab automation. Los ntawm kev qhia txog kev tswj hwm qib siab thiab cov khoom siv automation, kev tsim khoom thiab cov khoom zoo tuaj yeem txhim kho, thaum cov nqi tsim khoom thiab kev siv zog tuaj yeem raug txo. Qhov no yuav muab kev txhawb zog rau kev tsim kho kev lag luam ntawm monoethyl malonate.
I. Kev Sawv Rov Los ntawm Malonic Ester Kev Tshawb Fawb
Nyob rau hauv nruab nrab - mus rau - lig 19th caug xyoo, organic chemistry nkag mus rau lub sij hawm ntawm kev loj hlob sai, thiab kev tshawb fawb rau hauv cov synthesis thiab cov khoom ntawm ester compounds los ua ib qho tseem ceeb. Diethyl malonate, uas yog ib qho tseem ceeb ntawm cov organic hluavtaws intermediate, twb tau nyiam thoob plaws lub ntiaj teb. Nyob rau lub sijhawm ntawd, cov kws tshawb fawb tau tsom mus rau kev tshawb nrhiav cov tshuaj tiv thaiv malonic esters, sim npaj cov derivatives tshiab los ntawm hydrolysis, hloov pauv, thiab lwm yam kev cuam tshuam los muab cov cuab yeej ntxiv rau cov organic synthesis. Cov ntsiab lus tshawb fawb no tau tsim lub hauv paus rau kev nrhiav pomEthyl Hydrogen Malonate(EHM, CAS No. 1071-46-1). Raws li monoethyl derivative ntawm malonic acid, nws tau tshawb pom nyob rau hauv serendipitously nyob rau hauv - kev tshawb nrhiav tob rau hauv cov tshuaj tiv thaiv muaj feem xyuam rau diethyl malonate.
II. Ib yam khoom tshiab los ntawm Impurities (Late 19th Century)
Thawj qhov kev tshawb pom ntawm EHM hnub rov qab mus rau xyoo 1890 thiab txuas nrog rau kev ua haujlwm ntawm German chemist Laubenheimer. Nyob ib ncig ntawm 1891, thaum kawm txog cov tshuaj tiv thaiv ntawm fumaric acid thiab ethanol, Laubenheimer rhuab sib tov nyob rau hauv ib lub raj kaw ntawm 120℃kom txog thaum cov kua qaub tag nrho. Tom qab ntawd cov dej tau ntxiv rau cov kua dej cawv, ua rau cov tshuaj diethyl malonate rau precipitate. Txawm li cas los xij, poob nthav, flaky crystals sib cais los ntawm cov kua dej tsis huv thaum sawv ntsug. Nws kuj tau txais ib qho me me ntawm cov khoom siv los ntawm lwm txoj kev: saturating ib qho ethanolic kua ntawm malic acid nrog hydrogen chloride gas, ua raws li distillation. EHM tau kuaj pom nyob rau hauv qhov kawg distillate feem, tab sis cov txiaj ntsig tau qis heev, tiv thaiv qhov tseeb ntawm nws cov khoom.
III. Kev pom zoo thiab kev npaj ua kom zoo
Laubenheimer qhov kev tshawb pom tau cim qhov pib ntawm EHM kev tshawb fawb, tab sis nws cov qauv thiab cov khoom tsis raug txheeb xyuas vim qhov kev npaj ua ntej qis. Nyob rau hauv lub xyoo caum tom ntej no, chemists tau tshawb fawb ntxiv ntawm EHM, maj mam txhim kho nws cov kev npaj thiab cov qauv kev txheeb xyuas.Los ntawm lub xyoo pua 20th, kev nce qib hauv cov organic synthesis tso cai rau cov kws tshawb fawb los npaj EHM zoo los ntawm kev xaiv hydrolysis ntawm diethyl malonate, daws qhov teeb meem thaum ntxov ntawm cov qoob loo qis. Siv infrared spectroscopy, nuclear magnetic resonance, thiab lwm yam kev soj ntsuam, nws cov qauv tshuaj tau lees paub raws li 3-ethoxy-3-oxopropanoic acid (IUPAC lub npe), nrog ib tug molecular mis ntawm C₅H₈O₄ thiab molecular hnyav ntawm 132.115.
IV. Los ntawm Serendipitous Discovery mus rau Synthetic Intermediate
Txawm hais tias EHM tau tshawb pom los ntawm lub sijhawm, nws tau dhau los ua qhov tseem ceeb hauv kev sib txuas ntawm cov organic. Nyob rau hauv lub xyoo pua 20th lig, cov kws tshawb fawb tau lees paub nws cov khoom siv tshuaj lom neeg tshwj xeeb: nws koom nrog cov tshuaj tiv thaiv acylation, Knoevenagel condensations, thiab tuaj yeem siv rau hauv Dieckmann cyclization los npaj tetraacids. Nws kuj tseem ua lub luag haujlwm tseem ceeb hauv kev sib txuas ntawm -lactones.Los ntawm nws qhov kev tshawb pom tsis zoo nyob rau hauv lub xyoo pua 19th mus rau cov qauv kev pom zoo thiab kev nthuav dav hauv xyoo pua 20th, keeb kwm ntawm EHM kev tshawb fawb tsis tau tsuas yog nthuav cov tsev neeg ntawm malonic ester derivatives tab sis kuj txhawb kev tsim kho tshiab hauv organic synthesis, ntawm kev siv nyiaj txiag thiab kev tshawb fawb.
FAQ
Diethyl malonate siv rau dab tsi?
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Diethyl malonate yog sivNyob rau hauv kev npaj ntawm ntau cov tshuaj muaj txiaj ntsig zoo suav nrog vigabatrin, phenylbutazone, nalidixic acid, thiab rebamipide. Ntau cov tshuaj tua kab kuj tau tsim los ntawm diethylmalonate, suav nrog sethoxydim thiab derivatives ntawm 2-amino-4-chloro-6-methoxypyrimidine.
Dab tsi yog qhov ceev ntawm ethyl hydrogen malonate?
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1.119 g / ml ntawm 25 degree(lit.)
Dab tsi yog malonate tseem hu ua?
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PROPANEDIOIC ACID(MALONIC ACID) Propanedioic acid (Malonic Acid) yog dicarboxylic acid nrog cov qauv CH2 (COOH) 2. Daim ntawv ionized ntawm Propanedioic acid (Malonic Acid), nrog rau nws cov esters thiab ntsev, hu ua malonates.
Cim npe nrov: ethyl hydrogen malonate cas 1071-46-1, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom