Shaanxi BLOOM Tech Co., Ltd. yog ib tug ntawm cov uas paub txog manufacturers thiab lwm tus neeg ntawm mog (35-55) cas 149635-73-4 nyob Suav teb. Txais tos rau cov lag luam wholesale bulk zoo mog (35-55) cas 149635-73-4 muag ntawm no los ntawm peb lub hoobkas. Kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Moog (35-55)(Myelin Oligodendrocyte Glycoprotein) yog ib daim nyias nyias protein nyob rau hauv myelin sheath ntawm lub hauv paus paj hlwb, tshwj xeeb tshaj yog nthuav tawm nyob rau hauv lub plasma membrane ntawm oligodendrocytes. Nws yog glycoprotein, uas txhais tau hais tias nws cov qauv molecular muaj ob qho tib si cov protein thiab cov khoom qab zib. Cov protein feem ntau yog tsim los ntawm cov amino acid sequences, tsim ib tug ruaj khov peb -dimensional qauv los ntawm tej folding thiab conformation. Cov kab mob qab zib txuas rau cov protein thiab cuam tshuam rau kev ua haujlwm thiab kev ruaj ntseg ntawm myelin oligodendrocyte glycoproteinthrough glycosylation hloov kho. Ntawm qib molecular, MOGs muaj cov amino acid tshwj xeeb ua ntu zus thiab qhov chaw glycosylation.
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Customized Bottle Caps Thiab Corks:
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Catalog Txheej txheem cej luam
Mog (35-55) COA
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| Certificate of Analysis | ||
| Compound npe | Moog (35-55) | |
| Qib | Pharmaceutical qib | |
| CAS Nr. | 149635-73-4 | |
| Ntau | 39g | |
| Ntim txheem | PE hnab + Al foil hnab | |
| Chaw tsim tshuaj paus | Shaanxi BLOOM TECH Co., Ltd | |
| Ntau No. | 202501090035 | |
| MFG | Peb 9, 2026 | |
| EXP | Peb 8, 2029 | |
| Qauv |
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| Yam khoom | Enterprise txheem | Kev txheeb xyuas qhov tshwm sim |
| Qhov tshwm sim | Dawb los yog yuav luag dawb hmoov | Ua raws |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 5.0% | 0.54% |
| Poob rau ziab | Tsawg dua lossis sib npaug li 1.0% | 0.42% |
| Hnyav Hlau | Pb Tsawg dua lossis sib npaug li 0.5ppm | N.D. |
| Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Hg Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Cd Tsawg dua lossis sib npaug li 0.5ppm | N.D. | |
| Purity (HPLC) | Ntau dua lossis sib npaug li 99.0% | 99.98% |
| Ib leeg impurity | <0.8% | 0.52% |
| Tag nrho microbial suav | Tsawg dua lossis sib npaug li 750cfu / g | 95 |
| E. Coli | Tsawg dua lossis sib npaug li 2MPN / g | N.D. |
| Salmonella | N.D. | N.D. |
| Ethanol (los ntawm GC) | Tsawg dua lossis sib npaug li 5000ppm | 500ppm ua |
| Cia | Khaws rau hauv qhov chaw kaw, tsaus, thiab qhuav hauv qab -15 degree | |
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Cov kab ke thiab qhov chaw no txiav txim siab txog kev ua haujlwm lom neeg ntawm myelin oligodendrocyte glycoproteinthrough, nws cov kev cuam tshuam nrog lwm cov molecules, thiab nws qhov chaw nyob ntawm cov cell membrane. Raws li daim nyias nyias protein, MOG muaj cov khoom siv transmembrane, nrog ib feem nyob rau hauv lub cell thiab lwm qhov nyob rau sab nraum lub cell. Cov yam ntxwv no ua rau myelin oligodendrocyte glycoproteinthrough mus koom rau hauv intracellular thiab extracellular teeb liab transduction thiab cov txheej txheem pauv khoom. Myelin oligodendrocyte glycoproteinthrough ua lub luag haujlwm tseem ceeb hauv kev tswj hwm cell homeostasis thiab tswj kev ua haujlwm ntawm tes.
MOG plays lub luag haujlwm tseem ceeb hauv kev tswj cov qauv myelin thiab kev ua haujlwm, thiab cuam tshuam nrog ntau yam hauv nruab nrab paj hlwb demyelinating kab mob.Moog (35-55)(Myelin Oligodendrocyte Glycoprotein) yog ib qho tseem ceeb ntawm daim nyias nyias cov protein uas feem ntau qhia rau saum npoo ntawm oligodendrocytes nyob rau hauv nruab nrab lub paj hlwb. Nws ua lub luag haujlwm tseem ceeb hauv kev tswj cov qauv ib txwm muaj thiab kev ua haujlwm ntawm myelin sheath thiab koom nrog ntau yam txheej txheem lom neeg. Hauv qab no yog cov lus piav qhia ntxaws ntxaws ntawm txhua txoj haujlwm ntawm myelin oligodendrocyte glycoproteins.
1. Tsim thiab tu ntawm myelin sheath
Myelin oligodendrocyte glycoproteinthrough yog ib qho ntawm cov khoom tseem ceeb ntawm myelin sheath thiab tseem ceeb heev rau nws txoj kev tsim thiab kho. Lub myelin sheath yog ib txheej ntawm lipid zaj duab xis qhwv nyob ib ncig ntawm txheej txheej ntawm cov paj hlwb, uas muaj kev tiv thaiv thiab insulating cov teebmeem thiab tuaj yeem ua kom nrawm kis ntawm cov paj hlwb. MOG koom nrog hauv kev sib dhos thiab ruaj khov ntawm myelin sheaths los ntawm kev cuam tshuam nrog lwm cov proteins uas muaj feem xyuam nrog myelin. Nws tuaj yeem txhawb qhov kev tso tawm thiab kev npaj ntawm myelin lipids, tsim cov qauv myelin ntom, yog li ua kom muaj kev ua haujlwm ntawm cov paj hlwb.
2. Intercellular cov ntaub ntawv sib pauv
Myelin oligodendrocyte glycoproteinthrough, raws li ib tug membrane protein, nyob rau ntawm lub cell nto thiab muaj peev xwm cuam tshuam nrog lwm cov cell los yog extracellular matrix. Los ntawm kev lees paub thiab kev khi nrog lwm cov molecules, myelin oligodendrocyte glycoproteinthrough koom nrog hauv cov txheej txheem ntawm cov ntaub ntawv sib pauv. Nws tuaj yeem ua raws li receptor lossis ligand rau cov teeb liab hloov pauv, koom nrog hauv cov teeb liab hloov pauv thiab kev tswj hwm ntawm lub paj hlwb. Qhov kev sib pauv ntaub ntawv intercellular no yog qhov tseem ceeb heev rau kev tswj hwm kev ua haujlwm ntawm lub paj hlwb thiab koom tes ua haujlwm ntawm neurons.
3. Axon tiv thaiv thiab rov tsim dua tshiab
Oligodendrocytes tsim myelin sheaths los ntawm wrapping axons, muab kev tiv thaiv thiab kev noj haus kev txhawb nqa rau axons. Raws li ib feem tseem ceeb ntawm myelin sheath, MOG plays lub luag haujlwm tseem ceeb hauv kev tiv thaiv axons. Nws tuaj yeem tiv thaiv axons los ntawm kev puas tsuaj sab nraud thiab kev cuam tshuam ntawm cov khoom tsis zoo, tswj cov qauv kev ntseeg siab thiab kev ua haujlwm ruaj khov ntawm axons. Tsis tas li ntawd, hauv kev raug mob axonal lossis kab mob, myelin oligodendrocyte glycoproteinthrough kuj tseem tuaj yeem koom nrog kev tsim kho axonal, txhawb kev kho neuronal thiab rov ua haujlwm.
4. Kev tswj hwm kev tiv thaiv kab mob thiab kev sib koom tes kab mob
Nyob rau hauv xyoo tas los no, kev tshawb fawb ntau ntxiv tau pom tias MOG muaj feem cuam tshuam nrog kev tiv thaiv kab mob hauv lub hauv paus paj hlwb. Hauv cov kab mob demyelinating xws li ntau yam sclerosis (MS), qhov muaj thiab qhov txawv txav ntawm cov tshuaj tiv thaiv myelin oligodendrocyte glycoproteinthrough cov tshuaj tiv thaiv yog suav tias yog ib qho tseem ceeb ntawm cov kab mob pathogenesis. Cov tshuaj tiv thaiv kab mob no tuaj yeem tawm tsam MOG hauv cov ntaub qhwv myelin, ua rau myelin puas thiab poob, yog li ua rau lub paj hlwb tsis ua haujlwm. Yog li, kev kawm lub luag haujlwm ntawm myelin oligodendrocyte glycoproteinthrough hauv kev tiv thaiv kab mob yog qhov tseem ceeb heev.
5. Neurodevelopment thiab plasticity
Kev qhia thiab kev tswj hwm ntawm MOG ua lub luag haujlwm tseem ceeb hauv kev loj hlob, kev sib txawv, thiab tsim cov synaptic kev sib txuas ntawm neurons thaum lub sij hawm kev loj hlob ntawm lub paj hlwb. Los ntawm kev tswj hwm qib kev qhia ntawm myelin oligodendrocyte glycoproteinthrough, nws tuaj yeem cuam tshuam rau kev tsiv teb tsaws neuronal, axonal kev loj hlob, thiab tsim synaptic. Tsis tas li ntawd, MOG kuj tseem tuaj yeem koom nrog cov txheej txheem plasticity ntawm lub paj hlwb, uas yog, lub peev xwm ntawm cov neurons hloov kho lawv cov qauv thiab kev ua haujlwm thaum lub sijhawm hloov pauv ib puag ncig lossis kev kawm paub.
6. Kev sib cuam tshuam nrog lwm cov molecules
Raws li glycoprotein, cov suab thaj ib feem ntawm myelin oligodendrocyte glycoproteinthrough tuaj yeem cuam tshuam nrog lwm cov molecules, yog li cuam tshuam rau nws txoj haujlwm thiab kev ruaj ntseg. Tsis tas li ntawd, MOG tuaj yeem cuam tshuam nrog lwm cov proteins uas cuam tshuam nrog myelin, cytoskeletal proteins, thiab extracellular matrix proteins los koom ua ke tswj cov qauv thiab kev ua haujlwm ntawm myelin sheath. Cov kev sib cuam tshuam no yuav koom nrog ntau txoj hauv kev hloov pauv cov teeb liab thiab cov txheej txheem tswj hwm molecular, thiab xav tau kev tshawb fawb ntxiv los nthuav qhia lawv cov txheej txheem ntxaws.
7. Neural regeneration thiab kho
Thaum lub paj hlwb puas los yog cuam tshuam los ntawm cov kab mob, paj hlwb regeneration thiab kho yog cov txheej txheem tseem ceeb rau kev rov ua haujlwm. MOG, uas yog ib feem tseem ceeb ntawm myelin sheath, tej zaum yuav koom nrog hauv cov txheej txheem no. Los ntawm kev txhawb nqa kev loj hlob thiab kev sib txawv ntawm oligodendrocytes, nrog rau kev tswj hwm kev tsim kho thiab kev kho ntawm myelin sheaths, MOG pab kho cov qauv qub thiab kev ua haujlwm ntawm cov paj hlwb. Lub caij no, myelin oligodendrocyte glycoproteinthrough kuj tseem tuaj yeem txhawb txoj kev rov qab los thiab kev tsim kho ntawm lub paj hlwb los ntawm kev sib cuam tshuam nrog lwm yam kev tsim dua tshiab.
8. Kev tswj ntawm neural signal transduction
Lub xub ntiag ntawm myelin sheath ua rau kis tau tus mob neural signals sai thiab zoo. MOG, uas yog ib feem tseem ceeb ntawm myelin sheath, plays lub luag haujlwm tseem ceeb hauv kev tswj cov teeb liab neural transduction. Los ntawm kev tswj xyuas cov qauv kev ncaj ncees thiab kev ua haujlwm ruaj khov ntawm myelin sheath, MOG tuaj yeem ua kom muaj kev sib kis tau zoo ntawm cov teeb liab neural ntawm cov paj hlwb. Tsis tas li ntawd, myelin oligodendrocyte glycoproteinthrough kuj tseem tuaj yeem koom nrog hauv kev tswj hwm ntawm neural signal transduction los ntawm kev cuam tshuam nrog lwm cov teeb liab molecules, yog li cuam tshuam rau tag nrho cov haujlwm ntawm lub paj hlwb.
9. Koom nrog kev txhim kho thiab kev loj hlob ntawm cov paj hlwb
Thaum lub sij hawm txoj kev loj hlob ntawm lub paj hlwb, qhia theem ntawmmog (35-55)maj mam nce nrog kev loj hlob ntawm cov neurons thiab tsim ntawm myelin sheaths. Qhov no qhia tau hais tias myelin oligodendrocyte glycoproteinthrough ua lub luag haujlwm tseem ceeb hauv kev loj hlob thiab kev loj hlob ntawm lub paj hlwb. Los ntawm kev tswj cov kev qhia thiab kev ua haujlwm ntawm myelin oligodendrocyte glycoproteinthrough, nws tuaj yeem cuam tshuam rau txoj kev loj hlob thiab kev loj hlob ntawm cov paj hlwb, muab cov tswv yim tshiab rau kev tiv thaiv thiab kho cov kab mob neurological.
Moog (35-55),Lub myelin oligodendrocyte glycoprotein (35-55) fragment plays lub luag haujlwm tseem ceeb hauv kev tshawb fawb txog neuroscience, thiab nws txoj kev loj hlob zeem muag feem ntau cuam tshuam txog cov hauv qab no:
Qhov tseem ceeb zuj zus ntawm cov cuab yeej tshawb fawb tshawb fawb-Kev tshawb fawb tob ntawm cov kab mob hauv lub paj hlwb: Cov kab mob myelin oligodendrocyte glycoprotein (35-55) tawg, ua ib qho tseem ceeb ntawm cov paj hlwb hauv nruab nrab myelin, yog cov cuab yeej tseem ceeb rau kev kawm txog cov kab mob ntawm cov kab mob neurological xws li ntau yam sclerosis (MS). Nrog rau qhov tob ntawm kev tshawb fawb ntawm cov kab mob xws li MS, daim ntawv thov ntawm myelin oligodendrocyte glycoprotein (35-55) fragments yuav nthuav dav, uas yuav pab qhia tawm cov kab mob ntawm cov kab mob thiab muab lub hom phiaj tshiab rau kev kho mob.
Tsim tus qauv kab mob autoimmune-Lub myelin oligodendrocyte glycoprotein (35-55) fragment tuaj yeem ua rau muaj kev sim tshuaj autoimmune encephalomyelitis (EAE) thiab lwm cov qauv kab mob autoimmune, muab lub platform rau cov kws tshawb fawb los kawm txog cov kab mob thiab cov kab mob autoimmune. Nyob rau hauv lub neej yav tom ntej, nrog rau kev sib sib zog nqus ntawm kev tshawb fawb ntawm cov kab mob autoimmune, daim ntawv thov ntawm myelin oligodendrocyte glycoprotein (35-55) fragments hauv kev tsim cov qauv kab mob yuav ua tau ntau haiv neeg.Lub luag hauj lwm tseem ceeb ntawm kev tsim tshuaj thiab kev ntsuam xyuas-Tshiab tshuaj txoj kev loj hlob: Lub myelin oligodendrocyte glycoprotein5) fragment immunogenic (35-55) high ragmente immunogenicity. teb.
Cov yam ntxwv no ua rau nws yog ib qho tseem ceeb reagent rau kev soj ntsuam cov txiaj ntsig ntawm cov tshuaj tshiab lossis kev kho mob. Nyob rau hauv lub neej yav tom ntej, nyob rau hauv cov txheej txheem ntawm kev tsim tshuaj, myelin oligodendrocyte glycoprotein (35-55) fragments yuav siv ntau los tshuaj ntsuam thiab validate cov kev ua tau zoo ntawm cov neeg sib tw tebchaw, accelerating tus txheej txheem ntawm tshiab tshuaj launches.Personalized tshuaj: Nrog rau cov kev loj hlob ntawm precision tshuaj thiab tus kheej cov tshuaj, biomarkers xws li myelin oligodendrocyte (3 fwj) yuav ua tau ntau dua qhov tseem ceeb. lub luag haujlwm hauv kev kuaj mob thiab kev kho mob.
Los ntawm kev txheeb xyuas cov qib ntawm cov cim biomarkers xws li myelin oligodendrocyte glycoprotein (35-55) cov khoom tawg hauv cov neeg mob lub cev, cov phiaj xwm kho tus kheej kom meej dua tuaj yeem muab rau cov neeg mob.Kev xav tau kev lag luam thiab kev loj hlob muaj peev xwm-Kev lag luam nce ntxiv: Nrog rau kev laus ntawm cov pej xeem thiab kev nce ntawm cov kab mob ntawm cov hlab ntsha xws li kev xav tau ntawm cov hlab ntsha. oligodendrocyte glycoprotein (35-55) tawg yuav nce ntxiv.
Qhov no yuav txhawb kev tshawb fawb thiab tsim cov myelin oligodendrocyte glycoprotein (35-55) fragment txog cov khoom lag luam kom tau raws li kev xav tau ntawm kev ua lag luam.Technological innovation thiab industrial upgrading: Nrog rau kev nce qib thiab kev tsim kho tshiab ntawm biotechnology, cov txheej txheem tshawb nrhiav thiab kev siv ntawm biomarkers xws li myelin oligodendrocyte glycoprotein 5 (35-5) prefabricated ntau dua. Qhov no yuav txhawb kev txhim kho kev lag luam thiab kev tsim kho thev naus laus zis hauv thaj chaw ntawm neuroscience, muab lub sijhawm tshiab rau kev txhim kho myelin oligodendrocyte glycoprotein (35-55) fragments.
Cov kev sib tw thiab cov tswv yim daws teeb meem tau ntsib -Txawm hais tias cov khoom tawg ntawm myelin oligodendrocyte glycoprotein (35-55) muaj qhov kev loj hlob dav dav, nws kuj tseem ntsib qee qhov teeb meem xws li cov nqi npaj siab thiab kev ruaj ntseg tsis zoo. Txhawm rau daws cov teeb meem no, cov tswv yim hauv qab no tuaj yeem siv tau: Kev ua kom zoo ntawm cov txheej txheem kev npaj: Los ntawm kev txhim kho cov txheej txheem kev npaj thiab txo cov nqi tsim khoom, kev ua tau zoo thiab cov txiaj ntsig ntawm myelin oligodendrocyte glycoprotein (35-55) fragments tuaj yeem nce ntxiv, thiab lawv cov nqi lag luam tuaj yeem raug txo. Kev txhim kho kev ruaj ntseg: Los ntawm kev txhim kho cov txheej txheem khaws cia ntawm myelin oligodendrocyte glycoprotein (35-55). glycoprotein (35-55) fragments tuaj yeem txhim kho.
FAQ
A: MOG35-55 yog 35 mus rau 55 amino acid peptide fragment ntawm myelin oligodendrocyte glycoprotein nyob rau hauv nruab nrab paj hlwb. Nws yog tus kheej antigenic peptide nrog kev ua haujlwm encephalitis siab thiab tuaj yeem ua kom T thiab B cell tiv thaiv kab mob hauv lub cev. Nws yog ib qho cuab yeej classic peptide hauv kev tshawb fawb neuroimmune.
A: MOG35-55 core yog siv los tsim kev sim autoimmune encephalomyelitis (EAE) qauv hauv cov nas, simulating cov yam ntxwv ntawm ntau yam sclerosis. Nws kuj tseem tuaj yeem siv rau kev tsom xam ntawm cov txheej txheem neuroimmune, tshawb nrhiav cov kab mob ntawm cov kab mob autoimmune encephalopathy, kev tshuaj xyuas thiab kev ntsuas kev ua tau zoo ntawm cov tshuaj tiv thaiv kab mob thiab cov tshuaj tiv thaiv neuroprotective.
A: MOG35-55 tuaj yeem tsim cov tshuaj tiv thaiv kab mob autoimmune hauv lub cev, ua kom muaj cov teeb meem cuam tshuam los txhim kho cov ntshav-hlwb barrier permeability, txhawb inflammatory cell infiltration mus rau hauv nruab nrab paj hlwb cov ntaub so ntswg, tawm tsam myelin sheath qauv, ua rau demyelination puas, cuam tshuam nrog kev sib kis ntawm cov hlab ntsha, ntau yam kev hloov pauv ntawm cov hlab ntsha.
A: MOG35-55 muaj qhov ruaj khov thiab muaj peev xwm rov ua tau zoo hauv kev ua qauv, thiab tuaj yeem ua rau muaj kev cuam tshuam rov qab hom kab mob paj hlwb. Pathologically, nws nthuav tawm patchy demyelination yam ntxwv; Lub voj voog qauv yog tswj tau, hloov tau zoo rau cov tsiaj sim xws li nas thiab nas, thiab tsis ua rau lub cev lub cev ua haujlwm ntawm cov kab mob ib txwm muaj, ua rau nws tsim nyog rau kev siv sijhawm ntev thiab kev tshawb fawb txog tshuaj.
Cim npe nrov: mog (35-55) cas 149635-73-4, lwm tus neeg, manufacturers, hoobkas, lag luam wholesale, yuav, nqe, tej, kev muag khoom