Palmooloyl peptide

Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom lag luam thiab cov khoom lag luam Palmitoyl peptide hauv Suav teb. Txais tos rau kev lag luam wholesale ntau qhov zoo palmitoyl peptide rau muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.

Lub ntiaj teb los anti -}} ntev ntev li cov neeg siv khoom ua pov thawj {}} raws li cov txiaj ntsig uas xa cov txiaj ntsig ntsuas tau. Ntawm cov khoom muaj txiaj ntsig tshaj plaws yogPalmoolyl peptides{{0-} Cov lus piav qhia zoo nkauj ntawm ntuj kos duab molecules enterrier thiab hloov kho cov txheej txheem cellular. Cov peptides, feem ntau muaj cov amino acids nrog rau pawg neeg matrikines (mimic lub cev tau txais los ntawm extracellular kev ua haujlwm thiab collagen ntau lawm.

Cov ntaub ntawv ntxiv ntawm kev sib txuas lus:

Ob peb Palmitoyl peptides yog siv nyob rau hauv cov tshuaj pleev ib ce, txhua tus nrog cov khoom sib txawv:

● Palmitoyl Tripeptide- 1 (pal- ghk): nws pab txhim kho cov tawv nqaij elasticity, nws pab kom cov tsos ntawm wrinkles.

● Palmitoyl Tetrapeptide - 7 (pal {} gqpr): muaj kev pab txo cov tawv nqaij liab thiab voos.

Palmitoyl hexapeptide - 12 (pal-vgvapg): txhim kho cov tawv nqaij ruaj thiab kev txhawb nqa cov synthesis ntawm cov extracellular matrix.

● Palmitoyl Tripeptide}}}} 5 (syncics Lub cev muaj zog): Ua kom lub cev muaj zog los txhawb nqa cov tawv nqaij.

Qhov ua tiav kev koom tes ntawm Palmitoyl hmoov mus rau cov tshuaj pleev xim rau hauv cov tshuaj pleev ib yam yuav tsum ua tib zoo xav txog ntau yam:

► Saib siab thiab ruaj khov

Cov concentration ntawm palmitoyl peptides nyob rau hauv ib tug qauv muaj peev xwm cuam tshuam ntau yam lawv ua tau zoo. Txawm li cas los xij, ntau qhov kev xav tsis tas txhais tau cov txiaj ntsig zoo dua, thiab muaj ib qho kev pom zoo rau txhua tus peptide. Tsis tas li ntawd, kev ruaj ntseg ntawm Palmitoyl peptides tuaj yeem cuam tshuam los ntawm cov lus xws li pH, thiab muaj lwm cov khoom xyaw. Cov ntawv sau yuav tsum xyuas kom meej tias peptide tseem ruaj khov thoob plaws hauv cov khoom txee lub neej.

Compatibility nrog lwm cov khoom xyaw

Palmitoyl peptides yuav tsum tau sib xws nrog lwm cov khoom xyaw nquag hauv kev tsim kom tsis txhob muaj kev sib cuam tshuam uas yuav txo lawv txoj kev ua tau zoo. Piv txwv li, qee yam tshuaj ua haujlwm lossis surfactants yuav txwv peptides lossis cuam tshuam rau lawv solubility. Cov kws sau ua ke feem ntau ua kev ntsuas kev sib raug zoo kom ntseeg tau tias tag nrho cov khoom xyaw ua haujlwm synergistically.

Cov Kev Hloov Tshiab

Txhawm rau txhim kho kev nkag mus thiab ua tau zoo ntawm Palmitoyl peptides, ntau yam kev hloov pauv tuaj yeem ua haujlwm. Cov no suav nrog liposomes, nanosomes, thiab encapsulation technologies. Cov kab ke no tuaj yeem tiv thaiv cov peptides los ntawm kev ua tsis ncaj thiab pab txhawb lawv tus menyuam mus rau lub hom phiaj tawv nqaij txheej.

► Khoom Hom

PalmitoyL hmoov tuaj yeem cuam tshuam rau cov khoom siv kom zoo nkauj, suav nrog cov quav ua kom zoo nkauj, suav nrog cov quav ua kom zoo nkauj, suav nrog cov quav ua kom zoo nkauj, pleev xim, xas, thiab qhov ncauj qhov ntswg. Qhov kev xaiv ntawm cov khoom lag luam yog nyob ntawm cov txheej txheem kev xav tau thiab cov kev txhawj xeeb tshwj xeeb raug daws. Piv txwv li, ntshav qab zib yog nyiam rau lawv cov kev ntxhib los mos thiab muaj peev xwm xa cov khoom sib xyaw ncaj qha rau daim tawv nqaij.

Kev nyab xeeb ntawm Palmermoyl hmoov tau raug ntsuas ntau yam hauv ob qho tib si hauv Vitro thiab hauv Vivo kev tshawb fawb. Nov yog qee qhov kev txiav txim siab tseem ceeb hais txog nws qhov kev nyab xeeb:

► irritation thiab sensitization

Palmitoyl peptides feem ntau zoo -}}}}}}}}}}} Txoj kev pheej hmoo ntawm kev ua rau iritation lossis rhiab. Txawm li cas los xij, ib yam li muaj cov tshuaj pleev ib ce, muaj qhov uas tau txais kev cuam tshuam ntawm tus kheej. Nws raug nquahu kom ua cov duab kuaj ua ntej siv cov khoom muaj palmitoyl peptides, tshwj xeeb tshaj yog rau cov tib neeg muaj tawv nqaij.

E6 Toxicity Kev Kawm

Kev tshawb fawb toxicological tau qhia tias Palmermoyl peptides muaj kev ruaj ntseg kev ruaj ntseg. Kev kuaj ntshav thiab kev sim ncauj thiab dermal toxicity tau qhia tias cov peptides no tsis yog- kev lom zem siv hauv cov tshuaj pleev ib ce. Txuas ntxiv, Genotoxicity thiab mutagenicity chant tsis tau qhia txog cov kev pheej hmoo tseem ceeb.

Oct tau txais kev cai

Palmitoyl peptides tau siv dav hauv cov tshuaj pleev ib ce ntiaj teb txoj kev nyab xeeb rau cov neeg siv kev nyab xeeb rau cov neeg siv khoom hauv cov neeg siv khoom noj (SCCS Kev Pom Zoo no yog ua raws cov ntaub ntawv kev nyab xeeb thiab kev ntsuas kev pheej hmoo.

In Innovation Innovoratoryicies

Kev nce qib yav tom ntej hauv kev tsim thev naus laus zis Qhov no tuaj yeem suav nrog kev txhim kho cov kev hloov pauv ntau dua, xws li cov kab mob nanoparticles thiab kev ua kom muaj kev nkag siab thiab ua kom muaj kev sib tw ntawm palmitoyl peptides hauv daim tawv nqaij.

Pro► nthuav tawm rau cov ntawv thov tshiab

Thaum Palmitoyl hmoov feem ntau yog siv nyob rau hauv cov khoom lag luam Skincare, nws cov ntawv thov yuav txuas ntxiv tshaj li cov haujlwm no. Piv txwv li, nws tuaj yeem koom nrog cov khoom tu plaub hau kom txhim kho lub zog ua kom muaj zog thiab ci, lossis cov khoom siv tu kom sib ntxiv ntawm cov pos hniav. Tshawb nrhiav cov ntawv thov tshiab no tuaj yeem qhib cov kev loj hlob tshiab rau lub Palmitoyl hmoov kev lag luam.

Ins Muaj kev txhawb nqa thiab kev coj ua

Raws li cov neeg siv khoom tau ua ntau qhov kev xav tau ntau ntxiv, qhov kev thov kom muaj kev cia siab thiab coj tau cov khoom xyaw uas muaj kev cia siab. Cov neeg tsim khoom ntawm Palmoolyl hmoov yuav tsum paub meej tias lawv cov ntaub ntawv raw yog tsrouibly muaj npe thiab hais tias lawv cov txheej txheem ntau lawm yog ib puag ncig. Qhov no tuaj yeem koom nrog kev nqis peev hauv qhov chaw txuas ntxiv dua, txo cov khib nyiab, thiab txhawb kev ua haujlwm ncaj ncees.

PalmermoTl hmoov yog ib qho kev cog lus hauv kev cog lus thiab kev lag luam tus kheej, tsav los ntawm nws cov khoom lag luam thiab kev cog lus rau anti {{}} kev laus thiab ntuj; Thaum lub khw muag khoom ntsib xws li cov nqi ntau ntau thiab kev tswj hwm kev ua raws li cov zeem muag yav tom ntej rau Palmitoyl hmoov yog kaj. Nrog txuas ntxiv thev naus laus zis hauv Tsim Cov Technologies, nthuav mus rau hauv cov ntawv thov kom loj thiab kev coj ua tau zoo rau lub xyoo tom ntej.

Cov kab mob tseem ceeb ntawm cov kab mob neurodegenerative cov kab mob (Parkheimer tus kab mob, thiab tua kab mob txawv txav, cuam tshuam txog cov neeg neuronal membrane, thiab tsis sib xws ntawm Synapses. Xyoo tsis ntev los no, tus txheej txheem ntawm kev ntxiv palmomic acour rau cov phiaj xwm tseem ceeb rau kev cuam tshuam rau cov neeg muaj txiaj ntsig zoo hauv cov protein hauv zos, ruaj khov, thiab muaj nuj nqi.Palmooloyl peptide(palmosic acid -}}}}}}}}}} Txheem Peptide) muab cov tswv yim tshiab rau kev kho mob los ntawm kev tswj hwm tus txheej txheem no.

Lub hauv paus neurobiological ntawm Palm Plymation Kev Hloov Kho

 

Palm Plymation yog ib qho kev hloov kho Lipid ripid uas txuas 16 {}} palbon palricentic acid Ntsej Muag Kev Ntsuas, thiab kev cuam tshuam nrog cov protein. Nyob rau hauv lub paj hlwb, kwv yees li 45% ntawm synaptic protein (xws li ampar recetors, PSD-95, -YSnuclein) cia siab rau Palmimoylation los tswj lawv cov haujlwm:

Membrane Txoj Cai

Lub ZDHHC3 enzyme txhawb nqa cov kev qhia saum npoo ntawm Glua1 / GLUA2 Subngits los ntawm Palmimoylation, yog li txhim kho synaptic kis tau zoo. Lub Palmationlation ntawm psd - 95 sib kho nws anchoring rau membrane seceptors thiab tswj cov qauv synaptic-synaptic.

Protein muaj peev xwm

Palmimoylation tuaj yeem tiv thaiv cov protein los ntawm ubiquitination -} tshuaj kho. Piv txwv li, lub Palmoollation mediat los ntawm zdhhc ntawm fasn los ntawm kev sib tw inhibition ntawm txoj kev sib tw ruaj ruaj thiab txhawb nqa cov meuronal zog metabolism.

Inhibition ntawm pathological protein kev sib sau ua ke

Hauv Parkinson tus kab mob, lub Palmationlation ntawm - synuclein (kho kom haum rau nws kev sib cav sib ceg thiab qis ntawm cov neurotoxicity. Hauv HUNTONTON tus kab mob, Palmitterlation ntawm CY214 lub vev xaib ntawm cov tshuaj protein los ntawm kev txhim kho lub cytoplasmic kev sib sau ua ke ntawm mutant HTT.

Cov tswv yim kev cuam tshuam ntawm Palmitoyl Peptide

 

Raws li cov txheej txheem kev cai ntawm Palmationlation, Palmeroyl peptide interretental hauv nurodegenerative txoj kev hauv qab no:

Kev sib tw Palmitoylation / de - palmitoylation system:

Cov Inhibitor Kev Loj Hlob

Tsim me me molecule inhibitors tsom zdhhc21 (cuam tshuam nrog ad) lossis apt1 (cuam tshuam nrog palmitoylation lossis de {{kev hloov kho cov nqaij patological. Piv txwv li, cov apt1 inhibitor ML348 tuaj yeem kho cov solubility ntawm- synuclein thiab txhim kho lub cev muaj zog hauv pd nas qauv.

Activator application: Activate ZDHHC13/17 (HD-related) or ZDHHC3 (synaptic function-related) to enhance the palmitoylation of protective proteins. Piv txwv li, ZDHHC3 Activator tuaj yeem txhawb nqa Daim Ntawv Qhia Txog Membrane Inceple ntawm PSD-95 thiab Restore Synapic Versionistic.

Palmitylated Peptide Meaketics

Txhim kho lub membrane potneability: qhia palrmitterecation hloov kho peptroydation peptides (xws li BDNF, GDNF) kom nce lawv cov ntshav} Lub hlwb biecular penetration tus nqi thiab cellular uptake efficiency. Piv txwv li, cov palmooslated BDNF Mimetic Peptide tau txo cov ntawv xa tawm hauv cov qauv kev nkag siab thiab txhim kho kev ua haujlwm.

Kev Sib Tw Inhibition: Tsim PalmoolyLated Peptides uas muaj kev sib tw khi rau ZDHHCES lossis patological cov kev hloov kho tsis zoo. Piv txwv li, tus palmitoylated HTT - CYS214 peptide tuaj yeem txo cov mutt thiab ncua kev vam meej ntawm HD.

Cov Tswv Yim Kho Ua Ke

Kev koom tes nrog kev ua haujlwm tsis huv Piv txwv li, lub palmiableLated lub antibdy lub sij hawm nws ib nrab - lub neej los ntawm Membrane Anchoring thiab txhim kho cov quav hniav kev ua tau zoo.

Kev sib xyaw nrog cov kev tswj metabolic: phiaj lipid metabolism cuam tshuam hauv PD (xws li txo cov roj choposed), ntxiv rau cov roj ntsha ua kom rov kho dua tshiab ntawm - synuclein.

Cim npe nrov: PalmooloTl peptide, cov chaw muag khoom, chaw tsim khoom, Hoobkas, lag luam wholesale, yuav, nqe, loj, rau muag