Dl - asparagine monohydrate, tseem hu ua DL aspartic acid, DL aspartic acid, etc. Nws yog amino acid derivative thiab kuj tseem ceeb biochemical reagent. Its molecular formula is C4H8N2O3, CAS 3130-87-8, and it appears as white crystals with a pure appearance, no impurities, and no special odor. Nws muaj cov dej ua kom zoo thiab tuaj yeem yaj sai hauv dej. Tsis tas li ntawd, nws tuaj yeem rhuav hauv cov kev daws teeb meem acidic thiab alkaline, ua rau nws dav siv los ua cov kev tswj hwm lossis kev tswj hwm hauv kev sim biochemical. Nws tau siv dav hauv ntau thaj teb, tshuaj, kev ua liaj ua teb, tshuaj pleev ib ce, kev lag luam khoom noj, thiab kev lag luam ib puag ncig. Tab sis nws yog insoluble hauv ethanol thiab ether, nrog rau ntawm daim tawv nqaij, ob lub qhov muag, thiab ua pa. Nws yuav tsum tau muab cia rau hauv lub teeb thaiv thiab muab kaw ib puag ncig ntawm chav sov (10-30 degree).
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Tshuaj Cov Qauv |
C10H16N2O3S |
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Muaj pes tsawg leej |
244 |
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Molecular hnyav |
244 |
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m/z |
244 (100.0%), 245 (10.8%), 246 (4.5%) |
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Kev Ntsuam Xyuas |
C, 49.16; H, 6.60; N, 11.47; O, 19.65; S, 13.12 |
Dl - asparagine monohydrate, raws li ib qho tseem ceeb amino acid derivative, tau qhia dav cov kev thov hauv ntau daim teb.
1. Biochemical teb
(1) Kev npaj cov kab mob kab lis kev cai nruab nrab: DL asparagine monohydrate plays ib qho kev tshawb fawb tseem ceeb hauv microbiological tshawb fawb. Vim yog kev ua tau zoo rau kev loj hlob ntawm ntau cov kab mob me, cov kab mob uas tsim nyog rau cov kab lis kev noj haus kom tsim nyog rau lawv txoj kev loj hlob thiab luam.
(2) Kev tshawb fawb biochemical: hauv asparagine kev tshawb fawb, uas siv los ua ib qho kev kawm tseem ceeb, koom nrog kev kawm ntawm ntau cov txheej txheem metabolic. Los ntawm kev kawm nws cov teeb meem metabolic, cov txheej txheem ntawm kev nqis tes ua, thiab lwm yam tsis pub dhau lub neej, peb tuaj yeem nce kev nkag siab tob ntawm lub neej ua haujlwm ntawm cov kab mob.
(3) Lub Hlwb Ua Haujlwm Lub Hlwb: Asparagine, ua ib qho tseem ceeb amino acids, yog qhov tseem ceeb rau kev txhim kho lub hlwb ua haujlwm. DL asparagine monohydrate ua lub luag haujlwm tseem ceeb hauv kev ua haujlwm hlwb tuaj yeem pab tau kev nkag siab tob hauv lub cev ua haujlwm thiab kab mob ntawm cov leeg ntshav.
2. Kev Kho Mob
(1) Khoom siv yeeb tshuaj: DL asparagine monohydrate yog ib qho tseem ceeb raw rau synthesizing ntau yam yeeb tshuaj. Piv txwv li, nws tuaj yeem ua chav nruab nrab tseem ceeb rau cov tshuaj tua kab mob zoo nkauj, cov tshuaj tua kab mob, thiab cov khoom tseem ceeb rau kev txhim kho kev lag luam ntawm lub tshuaj.
(2) Kev kho mob kho mob: DL asparagine monohydrate nws tus kheej kuj muaj qee yam cuam tshuam ntawm cov chaw muag tshuaj, xws li antioxidant thiab antioxidant thiab antioxidant thiab antioxidant thiab antioxidant. Yog li ntawd, nws tuaj yeem siv ncaj qha rau kev kho mob ntawm qee yam kab mob, xws li cov kab mob tshwm sim, oxidation kev ntxhov siab ntsig txog cov kab mob muaj feem xyuam, thiab lwm yam.
(3) Cov neeg nqa tshuaj yeeb tshuaj: Vim nws cov dej so zoo thiab cov asparagine monohydrate kuj tseem siv tau los ua cov khoom siv tshuaj rau kev xa tshuaj thiab kev tso tawm. Los ntawm kev sib txuas nrog cov tshuaj los tsim cov complexes, lub hom phiaj xa tawm ntawm cov tshuaj hauv Vivo tuaj yeem ua tiav, txhim kho kev phiv tshuaj thiab txo cov kev phiv tshuaj thiab txo cov kev mob tshuaj.
3. Kev Ua Si
(1) Cov khoom noj cog: DL asparagine monohydrate tuaj yeem pab ua khoom noj khoom haus rau cov nroj tsuag, muab cov tshuaj nitrogen thiab cov khoom siv roj carbon. Los ntawm kev ntxiv nws cog cov kab lis kev cai nruab nrab lossis txau nws rau ntawm cov nroj tsuag cog thiab kev loj hlob, txhim kho cov nroj tsuag tawm thiab zoo.
(2) Kev ua liaj ua teb Biotechnology: Hauv kev ua liaj ua teb biotechnology, DL asparagine monohydrate kuj tseem ua lub luag haujlwm tseem ceeb. Nws tuaj yeem koom nrog kev siv roj ntsha ua rau cov txheej txheem ntawm biocatalyst, thiab lwm yam, muab cov tswv yim thiab cov hau kev tshiab rau kev txhim kho kev ua liaj ua teb biotechnology.
4. Tshuaj pleev ib ce teb
(1) moisturizing thiab moisturizing:Dl - asparagine monohydrateMuaj ntau cov kev siv hauv cov tshuaj pleev ib ce teb. Vim nws zoo heev moisturizing thiab moisturizing cuam tshuam, nws yog feem ntau ntxiv rau cov khoom siv tawv nqaij tawv, thiab lwm yam khoom los txhim kho cov ntsiab lus noo noo thiab cov khoom siv noo ntawm cov tawv nqaij.
(2) antioxidant thiab anti {{{{{{o} pa Nws tuaj yeem pab tshem tawm dawb radicals, inhibit mob tshwm sim, thiab lwm yam kev pab txhim kho kom txhim kho daim tawv nqaij thiab qeeb kev laus tawv nqaij.
(3) Txhim kho cov tawv nqaij tawv nqaij: DL asparagine monohydrate tseem tuaj yeem txhim kho kev ua haujlwm ntawm daim tawv nqaij, txhim kho daim tawv nqaij tiv taus thiab tiv thaiv cov tawv nqaij. Los ntawm kev ntxiv nws rau cov tshuaj pleev ib ce, nws tuaj yeem pab cov tawv nqaij tiv taus ib puag ncig sab nraud thiab voos.
5. Kev lag luam khoom noj
(1) Khoom noj ntxiv: DL asparagine monohydrate tuaj yeem siv ua khoom noj ntxiv rau txhim kho cov khoom noj thiab cov khoom noj muaj txiaj ntsig ntawm cov zaub mov. Piv txwv li, nws tuaj yeem raug ntxiv rau ntau yam khoom noj uas yog cov tsw ua kom zoo dua, kev noj haus kom zoo, thiab lwm yam.
(2) Khoom Noj Khoom Haus: Tsis tas li, dlua asparagine monohydrate kuj muaj qee yam cuam tshuam khaws cia. Nws tuaj yeem cuam tshuam cov kev loj hlob thiab kev luam ntawm cov microorganisms hauv cov zaub mov, txuas ntxiv lub txee lub neej thiab txee lub neej ntawm cov zaub mov.
6. Lwm liaj teb
(1) Kev tiv thaiv ib puag ncig: Hauv kev tiv thaiv ib puag ncig, DL asparagine monohydrate tuaj yeem siv ua biodegructable miodradable xws li wastewater thiab tso pa tawm. Los ntawm kev ntxiv nws rau cov kev kho mob, nws tuaj yeem txhawb nqa cov biodegradation thiab kev hloov cov txheej txheem ntawm cov pa phem, txo lawv cov kev xav thiab tshuaj lom.
(2) Kev Txhim Kho Cov Khoom Siv Tshiab: Ntxiv rau, DL Asparagine Monohydrate kuj tseem siv tau ua cov khoom siv raw rau kev txhim kho cov khoom tshiab. Los ntawm kev sib sau los yog kev hloov kho nrog lwm cov tshuaj, cov khoom tshiab nrog cov khoom tshwj xeeb tuaj yeem npaj, xws li biodegradable plastics, cov ntaub ntawv tshuaj tua kab mob, thiab lwm yam.
Dl - asparagine monohydrateyog ib qho tseem ceeb organic compound, thiab nws cov qauv saptthesis siv phenylacetic acid li cov khoom siv raw, uas tau npaj los ntawm ob peb kauj ruam. Hauv qab no, peb yuav muab cov lus qhia ntxaws ntxaws rau cov kauj ruam tshwj xeeb thiab tshuaj lom neeg thaum lub sij hawm sim.
Tag nrho cov kev phiv tshuav li yog raws li hauv qab no:
C6h5ch2Cooh + Naoh + HCL → C6h5Chiy2ConThiy2A + Nacl
Cov ntaub ntawv xav tau rau kev sim:
1. Phenyylacetic Acid
2. Sodium hydroxide (Naoh)
3. Hydrochloric acid (HCl)
4. Ethanol
5. Dej
Kev sim ua cov kauj ruam thiab tshuaj lom neeg:
1. Kev npaj ntawm sodium phenylacetate
Ntxiv cov phenyylacetic acid rau ib qho nyiaj tsim nyog, tom qab ntawd ntxiv cov khoom sodium hydroxide thiab do kom txog thaum uas yaj los ua cov sodium phenylacetate.
C6h5ch2Cooh + Naoh → C6h5ch2cola + H2O
Lub Hom Phiaj ntawm Txoj saw Sprockets
Metric Cov Menyuam Lub Tsheb Xiav Sprocket tuaj yeem siv rau yuav luag txhua yam ntawm cov kab ke. Siv hauv Conveyor Systems xws li cov khoom noj, nws tuaj yeem thauj khoom noj, dej haus, grain, thiab lwm yam khoom ntawm ib qho chaw mus rau lwm qhov chaw. Siv hauv kev xa tawm cov kab mob, nws hloov hluav taws xob los ntawm qhov chaw xws li lub cav rau ntau yam sib xyaw. Yog li no, cov khoom tseem muaj dav siv hauv liaj teb xws li tshuab tsim, khoom siv ua liaj ua teb, tsheb, thiab cov khoom siv tub rog.
2. Accification cov tshuaj tiv thaiv
Ntxiv sodium phenylacetate thiab hydrochloric acid mus rau qhov tsim nyog ntawm ethanol, thiab kho tus nqi ntawm ethanol, thiab kho tus nqi sib xyaw kom nws ntawm 4 - 5. Tom qab ntawd do cov tshuaj tiv thaiv sib xyaw rau 2 teev los ua kom muaj DL asparagine (d, l-aspartic acid).
C6h5ch2cola + HCL → C6h5ch2Cooh + Nacl
C6h5ch2Cooh + Naoh → C6h5ch2cola + H2O
C6h5ch2Cooh + Naoh + HCL → C6h5ch2Cooh + Nacl + H2O
3. Crystallization thiab ziab
Cov khoom tau los ntawm crystallization thiab pom ntawm cov tshuaj tiv thaiv kev sib xyaw yog DL asparagine. Tom qab ntawd qhuav dlpagine kom tau dlparagine monohydrate.
C6h5ch2Cooh + NH3 → C6h5ch2
C6h5ch2Conh 2+ h2o → C6h5ch2Conh ·o
Nws yuav tsum raug sau tseg tias cov xwm txheej ntawm txhua kauj ruam yuav tsum nruj me ntsis tswj tau thaum lub sij hawm sim ua kom ntseeg tau tias cov khoom lag luam thiab cov khoom lag luam zoo. Nyob rau tib lub sijhawm, kev nyab xeeb kuj tseem ceeb heev, thiab cov khoom tiv thaiv tsim nyog yuav tsum tau hnav thiab kuaj kom muaj kev nyab xeeb.
Qhov kev tshawb nrhiav ntawm dl asparagine monohydrate tuaj yeem raug rov qab mus rau lub xyoo pua puv 19, thaum cov chaw ua haujlwm hauv cov organic thiab biochemistry tau raug tsim kho tau sai sai. Cov kws tshawb fawb tau cog lus los nrhiav thiab synthesizing tshiab amino acid derivatives los tshawb lawv cov ntawv thov yuav nyob rau hauv cov chaw ntawm biochemistry thiab tshuaj. Nyob rau hauv cov ntsiab lus no, dllaragine monohydrate tau maj mam nkag mus rau kev tshawb nrhiav teb ua cov tshiab amino acid derivative. Kev tshawb fawb thaum ntxov tsuas yog tsom rau kev rho tawm thiab txheeb xyuas ntawm cov amino acids.
Xyoo 1806, Fabkis Chemist Louiselin thawj zaug cais asparagine los ntawm cov nroj tsuag asparagine los ntawm kev tshawb pom thawj zaug ntawm asparagine. Tom qab, cov kws tshawb fawb pib kawm cov tshuaj lom neeg thiab kev ua haujlwm ntawm asparagine.
Qhov kawg ntawm lub xyoo pua puv 19, German Chem tau ua rau muaj kev sib ceeb ntawm cov amino acids. Nws ua tiav cov lus qhia txog ntau yam cov amino acids thiab tau npaj siab rau cov amino acids, tso lub hauv paus rau tom qab peptide synthesis.
Thaum pib ntawm lub xyoo pua 20, nrog kev nce qib ntawm cov organic synthesis, cov kws tshawb fawb pib sim ua synthesis ntawm asparagine derivatives.
Xyoo 1901, German Chemist Hermann Emil Fischer thawj synthesized dl as synpagine, uas yog ib tug precepeor rau dl asparagine monohydrate. Fisher ua tiav synthesized dl asparagine los ntawm reacting aspartic acid nrog ammonia. Cov qauv hluavtaws no muab qhov tseem ceeb rau cov squthesis tom qab dl asparagine monohydrate.
Nyob rau hauv nruab nrab-20th caug xyoo, nrog qhov tob ntawm cov amino acid derivatives, synthesis txoj kev ntawm dl asparagine tau txhim kho monohydrate. Cov lus qhia ntawm cov catalysts tshiab thiab cov tshuaj tiv thaiv ua rau cov txheej txheem hluavtaws ntau dua thiab tswj tau. Piv txwv li, siv Dicyclohexylcarbodiimide (dcc) raws li lub condensing tus neeg sawv cev tuaj yeem txhim kho kev ua haujlwm ntawm aspartic acid thiab ammonia. Ib qho ntxiv, qhov ua tau zoo ntawm cov tshuaj tiv thaiv cov dej ntau ntxiv tau hloov dua tshiab ntawm DL asparagine monohydrate. Nyob rau lub sijhawm no, daim ntawv thov tau txais ntawm dlo as asparagine monohydrate maj mam nthuav dav. Cov kws tshawb fawb tau tshawb pom tias nws tsis tuaj yeem pab ua ib qho nrab hauv peptide synthesis, tab sis kuj tseem yog synthesizer rau kev tsim molal lwg metxules. Qhov kev tshawb pom no ntxiv ntxiv kev txhawb nqa daim ntawv thov kev tshawb fawb ntawm DL asparagine monohydrate hauv biochemistry.
Txij li thaum xyoo 1990, nrog kev txhim kho ntawm Combinatorial Chemistry thiab siab}} {}}}}}}}}} pa aspleagine tau nkag mus rau theem tshiab. Cov lus qhia ntawm cov cuab yeej siv hluav taws xob synctionize tau ua rau nws ua tau los synthesize thiab npo dlparagine monohydrate derivatives ntawm lub ntsuas loj. Ib qho ntxiv, kev siv lub khoos phis tawm -}}}}}}}}} Kev siv ntawm DL asparagine monohydrate hauv kev siv tshuaj yeeb.
Cim npe nrov: DL - asparagine Monohydrate Cas.30-87-8, Chaw tsim khoom, chaw tsim khoom, yuav khoom, khoom, rau muag