Txawm tiasGABA ntshiab hmoovtsuas yog paub nyob rau hauv xyoo tas los no, keeb kwm ntawm kev tshawb pom thiab tshawb nrhiav nws tuaj yeem taug qab mus rau ib nrab xyoo dhau los. Nyob rau hauv 1950, Florey thiab Robert pab neeg nrhiav tau nyob rau hauv mammalian hlwb rho tawm. nws tau pom zoo thawj zaug rau kev siv tshuaj kho mob hauv xyoo 1961. Xyoo 1975, nws tau lees paub tias yog ib qho tseem ceeb inhibitory neurotransmitter nyob rau hauv mammalian paj hlwb ntawm lub thib ob thoob ntiaj teb Symposium. Cov kev tshawb fawb saum toj no tau tsim lub hauv paus ruaj khov rau nws kom nkag mus rau tib neeg kev noj haus txhua hnub thiab txhim kho kev ua neej zoo.
Nyob rau hauv cov nqe lus ntawm kev ua lag luam daim ntawv thov, nyob rau hauv 2001, Nyiv lub Ministry ntawm kev noj qab haus huv, kev ua hauj lwm, thiab kev noj qab haus huv pom zoo cov khoom noj raw khoom. Taiwan Tuam Tshoj tus thawj coj saib xyuas kev noj qab haus huv tau teev nws ua cov khoom noj khoom haus hauv tib lub xyoo. Xyoo 2009, Tuam Tshoj Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv tau pom zoo cov peev txheej tshiab rau zaub mov. Kev siv: dej haus, khoom siv cocoa, khoom qab zib thiab khoom qab zib, khoom qab zib, khoom noj ci, thiab zaub mov puffed, tab sis tsis suav nrog cov khoom noj me nyuam mos. Txog tam sim no, daim ntawv thov zaub mov tau qhib lub qhov rooj rau lub tebchaws, muab cov neeg siv khoom xaiv kev noj haus tshiab.
Niaj hnub no, cov khoom noj uas muaj nws tau tsim tawm txawv teb chaws tau ntau xyoo. Raws li lub Rau Hli 20, 2019, lub koom haum Nyiv Pooj tau pom zoo 239 cov khoom noj uas muaj nws, suav nrog yogurt, dej haus, kua hauv qhov ncauj, thiab lwm yam. nws nyob rau qib thib ob ntawm cov khoom siv raw ntawm cov khoom noj muaj npe nyob hauv Nyiv.
Raws li cov khoom noj khoom haus tshiab hauv Suav teb, nws yog "vitamin paj hlwb." Nws yog dav siv nyob rau hauv cov khoom siv so thiab pw tsaug zog rau cov neeg muaj zog siab, cov khoom siv so thiab pw tsaug zog rau cov neeg muaj zog, thiab cov khoom siv kho kom zoo nkauj rau cov neeg nyiam kev zoo nkauj.
Huaxi biology, lub tuam txhab ua lag luam biotechnology, coj tus thawj coj hauv kev tsim cov khoom noj muaj txiaj ntsig zoo los ntawm microbial fermentation hauv Suav teb, hloov cov txheej txheem cog qoob loo yav dhau los thiab muab kev txhawb zog rau kev pub mis. fermentation yield thiab raw khoom zoo tau nyob rau theem siab tshaj. nws cov khoom siv raw khoom ntawm lub tuam txhab tau txais ntawv pov thawj halal zaub mov thiab kosher cov neeg Yudais huv zaub mov ntawv pov thawj. Nyob rau hauv cov nqe lus ntawm cov khoom kawg, Huaxi biology tau launched cov khoom uas muaj － "Wuliuquan qab zib npau suav haus" thiab "dub zero" mos khoom qab zib ntawm aminobutyric acid tau txais tos los ntawm cov neeg siv khoom nrog lawv tus kheej cov neeg siv kev paub zoo.
Tam sim no peb paub ntau yam txog nws cov txiaj ntsig, peb yuav ua li cas ntxiv nws kom tsim nyog hauv peb lub neej txhua hnub? Tom ntej no, cia peb qhib qhov tseeb posture ntawm kev nyab xeeb nce nws. Ntxiv nrog rau cov khoom noj khoom haus ncaj qha, peb tseem tuaj yeem tau txais lawv los ntawm cov khoom noj ntuj, xws li cov noob qoob loo, spinach, qos yaj ywm, qos yaj ywm qab zib, cruciferous nroj tsuag, nceb, txiv lws suav, tshuaj yej dawb, thiab lwm yam., fermented zaub, thiab dej haus, xws li yogurt. Tsis tas li ntawd, txawm tias nws muaj ntau yam teebmeem, peb tsis tuaj yeem overeat yam tsis muaj kev txwv. Pom zoo los ntawm National Health thiab Family Planning Commission ntawm Tuam Tshoj xyoo 2009, - Aminobutyric acid, cov khoom noj tshiab, tuaj yeem siv rau hauv kev ua zaub mov. Nws tau teev tseg tias nws noj tsawg dua lossis sib npaug li 500 mg / hnub.
Hauv luv, nws muaj kev nyab xeeb noj nws ntev npaum li nws tsis dhau. Thaum koj tsaug zog heev thaum nruab hnub thiab pw tsis tsaug zog thaum hmo ntuj; nyuaj siab heev; Tsis ua hauj lwm hnyav tab sis nkees tas li; chim siab, los yog nyob tsis tswm, tej zaum nws yuav pab tau koj!
Synthetic GABlos ntawm cog enrichment:
Txoj kev cog qoob loo yog ib qho tshiab tsim hluavtaws extraction thiab purification technology. Nws siv cov nroj tsuag nrog cov ntsiab lus siab rau kev sib cais thiab kev rho tawm kom muaj GABA cov khoom uas pheej yig thiab siab purity. Muaj ob txoj hauv kev kom tau txais GABA los ntawm cov nroj tsuag: hnyav extraction thiab purification thiab kem sib cais thiab npaj.
(1) Cov kuab tshuaj extraction
Cov kuab tshuaj extraction siv dej los yog cawv ua tus neeg sawv cev ntawm nws. Raws li lub hauv paus ntsiab lus ntawm kev sib txawv solubility thiab muab faib coefficient ntawm cov nroj tsuag hauv dej los yog cawv, nws yog muab tso rau hauv dej los yog cawv. Tom qab rov ua dua thiab ua kom huv, feem ntau cov nroj tsuag tuaj yeem muab rho tawm.
(2) Txoj kev npaj cais kab ke
Txoj kev npaj sib cais kem, tseem hu ua kem chromatography, yog ib hom kev sib cais elution thiab lwm yam kev ua haujlwm tom qab raws li lub hauv paus ntsiab lus uas cov khoom sib txawv sib txawv muaj qhov sib txawv sib txawv hauv cov khoom ua kua ob theem. Nws cov kev faib loj yuav tsum yog nyob rau hauv chromatography. Resin, silica gel, lossis cov pa roj carbon activated feem ntau yog siv los ua cov khoom ntim rau cov kab chromatographic.
Physiological teebmeem ntawm nws: 50mmol / L thiab cov ntsev sib txawv yuav muaj kev cuam tshuam sib txawv ntawm cov nroj tsuag cog. Thaum NO3 - ion qis dua 40mmol / L, nws yuav ua rau cov hauv paus elongation, thiab thaum NO3 - ion tseem ceeb dua 40mmol / L, nws yuav ua rau cov hauv paus elongation. Tsis tas li ntawd, nws txhawb nqa qhov nqus ntawm qhov tsis tshua muaj siab NO3 - thiab inhibits qhov nqus ntawm cov concentration siab NO3 -, thaum GS thiab lwm cov enzymes tswj hwm los ntawm nitrogen. Cov kev tshawb fawb saum toj no ntseeg tias nitrogen ua lub luag haujlwm tshwj xeeb hauv kev tswj cov nroj tsuag kev loj hlob. Raws li kev txhawb nqa ntawm NaCl (50mmol / L), glycosylation metabolism ntawm cov nroj tsuag yuav pib hloov pauv thiab cuam tshuam cov kev hloov pauv, suav nrog lub voj voog tricarboxylic acid, nws cov metabolism, amino acid synthesis, thiab shikimic acid-mediated secondary metabolism. Cov ntsev ions siab dua yuav ua rau oxidative degradation ntawm polyamines hauv cov taum pauv rau nws. Nroj tsuag GABA ntshiab hmoovreceptors muaj lub hauv paus kam rau ua tswj pH thiab Al3 ntxiv.