Shaanxi Bloom Tech Co., Ltd. yog ib qho ntawm cov neeg tsim khoom thiab cov chaw muag khoom tshaj plaws thiab cov khoom siv vancomycin hmoov qub 1404-90-6 nyob rau hauv Suav teb. Txais tos rau kev lag luam wholesale tej yam zoo tshaj cov ntsiab lus vancomycin hmoov uas 1404-90-6 Cia muag ntawm no los ntawm peb lub hoobkas. Cov kev pabcuam zoo thiab tus nqi tsim nyog muaj.
Txoov Vancomycin Hmoov, Vancomycin hmoov yog cov tshuaj noj hauv zos thov tshuaj tua kab mob. Los ntawm inhibiting cell phab ntsa synceptesis ntawm cov tshuaj lom neeg ntawm lub synhucleic acid, cov tshuaj tua hluav taws xob tau muab ntau dua. Nws cov hmoov hmoov yooj yim rau daim ntawv thov hauv zos, xws li cuam tshuam ncaj qha rau ntawm cov qhov txhab lossis chaw phais, tsis muaj kev sib xyaw nrog cov khoom noj muaj sia lossis lwm yam ntaub ntawv. Thaum siv, saib xyuas yuav tsum tau them rau qhov ntau npaum thiab ntau zaus ntawm kev noj tshuaj, nrog rau kev nyiam huv thiab kev ua kom huv ntawm lub qhov txhab. Nws cov tsos feem ntau tshwm los ntawm dawb lossis tawm dawb hmoov. Cov hmoov no tsis muaj ntxhiab, tab sis muaj qhov iab iab thiab yog cov soluble yooj yim hauv acidic aqueous daws. Txawm hais tias nws tuaj yeem yaj nyob rau hauv kev daws teeb meem alkaline, nws tsis ruaj khov. Txawm li cas los xij, nws yog me ntsis soluble hauv methanol thiab nyuaj kom yaj sab hauv lwm cov kuab tshuaj organic. Nws yog siv rau hauv kev phais mob uas nquag kis tau, xws li kav cov hmoov av, thiab cov vancoal pob txha lov, uas muaj peev xwm txo qis tus nqi kho mob ntawm qhov chaw phais mob. Ib txhij tsuas yog thov vancomycin hmoov nyob hauv zos tuaj yeem pab txo cov kab mob suav ntawm lub qhov txhab zoo thiab txhawb kev ua rau kho kom zoo.
Cov ntaub ntawv ntxiv ntawm kev sib txuas lus:
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Tshuaj Cov Qauv |
C66H75Cl2n9o24 |
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Muaj pes tsawg leej |
1447.43 |
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Molecular hnyav |
1449.27 |
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m/z |
1447.43(100.0%),1448.43(71.4%),1449.43(63.9%),1450.43(45.6%),1449.44(25.1%), 1451.43(16.0%),1451.42(10.2%),1452.43(7.3%),1450.44(5.8%),1449.43(4.9%), 1450.44(3.5%),1452.44(3.2%),1451.43(3.2%),1448.43(3.0%),1453.43(2.6%), 1449.43(2.4%),1452.43(2.3%),1450.42(2.1%),1451.43(1.3%),1451.44(1.2%) |
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Kev Ntsuam Xyuas |
C, 54.70; H, 5.22; Cl, 4.89; N, 8.70; O, 26.49 |
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Melting taw tes |
>274 Qib (Dec.) |
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Ceev |
1.2882 (ntxhib kwv yees) |
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Kev Cia |
2-8 degree |
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Txoov Vancomycin HmoovFeem ntau yog siv nyob rau hauv cov teb kho mob, tshwj xeeb hauv kev tiv thaiv thiab kev kho mob ntawm kev sib kis tau hais txog kev phais mob lossis raug mob. Hauv qab no yog cov ntsiab lus piav qhia ntxaws ntxaws ntawm nws cov kev siv:
Kev phais mob chaw yog ib qho ntawm cov kev phais mob tom qab kev phais, uas yuav ua rau phais mob tsis ua haujlwm, kev ua haujlwm kho mob ntev, thiab ua kom tus neeg mob nce siab. Yog li, kev tiv thaiv kev tiv thaiv kab mob yog qhov tseem ceeb tshaj plaws rau kev kho kom rov zoo ntawm cov neeg mob thiab kev txhim kho kev kho mob zoo. Vancomycin yog cov tshuaj tua kab mob glycopeptide nrog rau dav -} spectrum antibacterial kev ua. Nws tiv thaiv cov hluavtaws ntawm tes los ntawm kev cuam tshuam nrog cov tseem ceeb Peptidoglycan hauv cov kab mob ntawm phab ntsa phab ntsa, yog li ua tiav cov txiaj ntsig ntawm phab ntsa. Siv hauv zos ntawm Vancomycin hmoov tuaj yeem paub tseeb tias cov tshuaj ncaj qha ua rau ntawm qhov chaw phais, nce tshuaj yeeb tshuaj, thiab muaj ntau tus kab mob sib tiv thaiv kab mob.
VANCOMYCIN hmoov tuaj yeem thov ncaj qha rau kev phais mob los txo kev pheej hmoo ntawm kev phais mob chaw phais. Qhov no muaj ntau yam nyob rau hauv Orthopedic phais, tshwj xeeb tshaj yog kev pheej hmoo kis, xws li kev sib kis tau ntau dua, xws li pilon pob txha lov, thiab calcaneal pob txha lov. Kev tshawb fawb tau pom tias piv rau cov pab pawg tswj hwm uas tsis siv Vancomycin Hmoov, tsis siv daim ntawv thov hauv zos ntawm Vancomycin hmoov tuaj yeem txo tus kab mob sib kis.
Tiv Thaiv Kev Txhaum Cai
Kev phais mob Orthopedic: Hauv kev phais mob Orthopedic, tshwj xeeb tshaj yog cov kev cog lus xws li kev phais mob txha caj qaum thiab kev tiv thaiv kev pheej hmoo ntawm kev tiv thaiv tus kab mob. Cov kev tshawb fawb tau pom tias piv rau cov pab pawg tswj hwm uas tsis siv Vancomycin Hmoov, cov neeg mob uas tau siv tus kab mob vancomycin muaj tus kab mob qis dua. Kev siv cov tshuaj no kuj tseem tuaj yeem txo cov kev tshwm sim ntawm kev phais mob raum, uas yog qhov tseem ceeb rau tus neeg mob rov qab thiab phais mob.
Yuav siv lwm yam kev phais mob: Ntxiv rau kev phais mob orthopedic, Vancomycin hmoov kuj tseem siv tau rau lwm hom kev phais mob txhawm rau txhawm rau tiv thaiv kab mob phais. Piv txwv li, hauv kev hloov kho cov khoom phais mob Txawm li cas los xij, qhov ua tau zoo ntawm daim ntawv thov no txawv nyob rau hauv kev kawm sib txawv thiab kev tshawb fawb ntxiv yog xav tau los txheeb xyuas nws.
Vanmomycin, raws li cov tshuaj tua kab mob glycopepiotion, muaj cov tshuaj tua kab mob ua si ntawm cov kab mob vanconiae, thiab lwm yam khoom noj muaj txiaj ntsig los kho kab mob tshwm sim los ntawm cov no Cov kab mob, tshwj xeeb tshaj yog cov tawv nqaij thiab cov hniav muag muag.
Thaum ua ntawv thov vancomycin hmoov nyob hauv zos, ib qho koob tshuaj ntawm vancomycin hmoov feem ntau yog siv rau qhov chaw phais, thiab lwm yam. Feem ntau hais lus, thaum siv, nws yog ib qho tsim nyog los xyuas kom cov tshuaj xyuas cov ntaub ntawv phais mob tusyees thiab zam nws nrog cov khoom noj muaj sia lossis lwm yam ntaub ntawv.
Kho cov kab mob tshwj xeeb
Kev phais mob txha caj qaum: Hauv zos prophylactic daim ntawv thov ntawm Vancomycin hmoov tau siv dav hauv kev phais mob caj qaum. Ntau cov kev tshawb fawb tau pom tias cov pab pawg sim kho nrog Vancomycin muaj qhov cuam tshuam me me ntawm kev sib kis mob curinal phais
Kev txheeb ze plaub fab pom tias Vancomycin tau txo qis kev pheej hmoo ntawm qhov chaw phais mob.
Orthopedic phais: Cov ntaub ntawv hauv zos ntawm Vancomycin hmoov kuj tseem ua tiav cov txiaj ntsig zoo xws li kev mob hnyav, Pilon pob txha lov Kev tshawb fawb tau pom tias kev siv Vancomycin tuaj yeem txo qis tus kab mob phais kab mob tom qab cov kev phais mob me.
Sau ntawv thiab ntsiab lus
- Cov tshuaj muaj kev tshuaj yeeb: ua ntej siv vancomycin thiab cov kab lis kev cai thiab kev siv tshuaj uas rhiab heev uas tau xaiv cov tshuaj uas tau xaiv rau cov kabmob.
- Cov kev sib raug zoo: Txawm hais tias daim ntawv thov hauv zos ntawm Vancomycin muaj qee qhov kev tsis zoo, tseem yuav tau them rau cov kev tsis haum, thiab lwm yam kev tsis zoo hauv cov neeg mob. Thaum siv, cov neeg mob cov kev hloov pauv yuav tsum tau saib xyuas kom zoo thiab hais kom sai.
- Kev sib cuam tshuam yeeb tshuaj: Vancomycin yuav cuam tshuam nrog lwm cov tshuaj, yog li nws yog ib qho tseem ceeb kom tau nkag siab tus neeg mob lub keeb kwm kev noj tshuaj ua ntej siv kom tsis txhob muaj kev cuam tshuam los ntawm kev siv tshuaj yeeb.
Daim ntawv thov hauv zos ntawm Vancomycin hmoov hauv kev kho mob tshwj xeeb muaj cov kev sib tw tseem ceeb, tshwj xeeb yog hauv kev phais mob txha caj qaum thiab qee qhov kev phais mob phais mob. Txawm li cas los xij, tseem muaj kev sib cav hais txog nws cov kev siv tshuaj thiab txoj kev siv, thiab ntau txoj kev tshawb fawb siab yog xav tau los ntsuas nws cov hauj lwm zoo thiab kev nyab xeeb. Thaum siv cov lus qhia txog kev kho mob thiab cov lus qhia txog kev siv tshuaj yuav tsum ua raws li kom muaj kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb thiab siv tau kev nyab xeeb.
Cov tshwm sim ntawm cov khoom no yog dab tsi?
Hais txog kev phiv los ntawmTxoov Vancomycin Hmoov, Txawm hais tias nws muaj qis dua kev phiv tshuaj rau cov ntawv thov systemicic, tseem muaj qee qhov tshwm sim tshwm sim thiab txaus ntshai. Hauv qab no yog cov ncauj lus kom ntxaws ntxaws ntawm nws cov kev phiv:
1.Local phiv
Daim tawv nqaij voos
Hmoov rau hauv zos ntawm Vancomycin hmoov yuav ua rau cov ntshav pancomycin yuav ua rau cov tsos mob tsis zoo xws li kev liab, o, mob, lossis khaus. Cov tsos mob no feem ntau yog me me thiab tuaj yeem daws tus kheej tom qab ua kom tiav cov tshuaj.
Kev tsis haum
Txawm hais tias daim ntawv thov hauv zos txo qhov kev pheej hmoo ntawm kev ua xua, qee tus neeg mob tseem tuaj yeem ua pob hauv zos ua xua rau vancomycin, tshwm sim li pob, erythema, thiab lwm yam.
2.Systemic phiv los (sib npaug)
Cov ntshav npau suav
Txawm hais tias daim ntawv thov hauv zos ntawm Vancomycin muaj cov nepomycin muaj tsawg, ntev {}} lub sijhawm lossis ntau dhau yuav ua rau muaj kev puas tsuaj rau lub raum. Yog li, tus neeg mob lub raum muaj nuj nqi yuav tsum tau saib xyuas kom zoo thaum siv.
Hepatotoxicity
Muaj cov ntaub ntawv tshaj tawm tias daim ntawv thov hauv zos ntawm Vancomycin kuj tseem yuav ua rau lub siab tsis sib xws, ua kom pom kev hloov pauv qib siab. Rau cov neeg mob nrog ua ntej {{- Kev tiv thaiv daim siab, yuav tsum tau ceev faj thaum siv nws.
Lwm qhov system tshua
Ib tug me me ntawm cov neeg mob yuav muaj kev phiv tsis zoo, ntuav, mob taub hau me me thiab kho tus kheej tom qab ua kom pom kev noj tshuaj.
3. Kev phom sij rau cov neeg tshwj xeeb
Cev xeeb tub thiab tub rog poj niam
Kev nyab xeeb ntawm daim ntawv thov hauv zos ntawm Vancomycin tsis tau muaj kev soj ntsuam txhua lub cev xeeb tub thiab lactating poj niam. Yog li ntawd, yuav tsum ceev faj thaum siv nws nyob rau hauv cov neeg no thiab ua raws cov kev taw qhia ntawm tus kws kho mob.
Cov menyuam
Kev nyab xeeb ntawm kev siv vancomycin hauv cov menyuam yaus tseem xav tau kev saib xyuas tshwj xeeb. Vim tias qhov sib txawv hauv cov qauv ntawm lub cev thiab cov txheej txheem metabolic ntawm cov menyuam yaus thiab cov neeg laus, yuav tsum tau hloov kho kom haum raws li muaj hnub nyoog, qhov hnyav, thiab mob thaum siv nws.
4. Kev ceev faj rau kev siv
- Tshuaj Ntshiab: Ua ntej sivTxoov Vancomycin Hmoov, Kab Mob Kab Mob thiab Tshuaj Lom Cov Tshuaj Ntsuam Xyuas Kev Kuaj yuav tsum ua kom ntseeg tau tias cov tshuaj uas tau xaiv tau nkag siab rau cov kab mob lub hom phiaj.
- Zam kev sib xyaw nrog lwm cov tshuaj: thaum ua ntawv thov Vancomycin Topically, nws yuav tsum zam kev sib xyaw nrog lwm cov tshuaj los tiv thaiv kev ua yeeb yam tshuaj yeeb lossis cuam tshuam rau cov tshuaj.
- Kev soj ntsuam cov kev hloov pauv ntawm tus neeg mob: thaum siv, tus neeg mob tus mob yuav tsum tau saib xyuas kom sai thiab ua rau muaj kev cuam tshuam tsis zoo.
Lub ntsiab tivthaiv ntawmTxoov Vancomycin Hmoovyog VANCOMYCIN, uas yog cov tshuaj tua kab mob glycopeptide. Nws cov qauv tshuaj muaj cov qauv sib tw glycosylated peptide. Cov mis molecular yog c₆₆heccl₂n₉o₂₄, nrog txoj kev sib dhos ntawm 1449.25. Nws cov tshuaj lom neeg muab nws tshwj xeeb rau nws cov kev siv tshuaj tua kab mob hauv zos, tshwj xeeb tshaj yog kev tiv thaiv kab mob hauv teb thiab phais mob plawv.
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Lub xeev lub xeev thiab ruaj khov
Lub zos Vancomycin hmoov yog ib qho ze li dawb hmoov zoo nrog hygroscopic cov khoom. Nws yuav tsum muab cia rau hauv cov thawv ntim hauv ib puag ncig qhuav. Nws cov ruaj khov yog cuam tshuam los ntawm qhov kub: Cov khoom hmoov tuaj yeem khaws cia rau hauv cov kuab tshuaj (xws li cov neeg ua kom yaj tau), nws yuav tsum tau khaws cia rau -65 degree, nrog lub sijhawm luv luv mus rau 2 xyoos. Qhov kev xav tau kev ruaj khov no yuav tsum nruj kev tswj qhov kub thiab kev thauj mus los txhawm rau tiv thaiv kev txo qis hauv kev rov qab khov thiab yaj.
Solubility thiab sib xyaw
Cov hmoov daim ntawv ntawm Vancomycin yog me ntsis soluble hauv duethyl sulfoxide (DMOPS), thiab yuav luag tsis muaj dej nyob hauv cov kuab tshuaj thiab ethanol. Txawm li cas los xij, nws tuaj yeem npaj rau hauv dej -} soluble txuj ci los ntawm cov txheej txheem tshwj xeeb. Hauv cov ntawv thov hauv zos, 1g ntawm cov hmoov feem ntau tau kis ncaj qha rau kev phais mob lossis qhov pom ntawm qhov tsis muaj kev xav tau sib xyaw nrog cov kuab tshuaj. Qhov no tus yam ntxwv ua rau cov txheej txheem ua haujlwm thiab txo qis kev pheej hmoo ntawm kev paug. Nws yuav tsum raug sau tseg tias Vancomycin tsis muaj tus ntoo khaub lig}}}} {{{{{{{{{{{{{{{} Thaum tsim cov nag lossis daus nrog qee cov hlau ions.
Cov tshuaj tua kab mob thiab tshuaj lom neeg
The antibacterial activity of vancomycin stems from its unique chemical structure: by highly affinity binding to the D-proline-D-alanine at the peptide terminus of the bacterial cell wall precursor, it blocks the synthesis of the peptidoglycan backbone, resulting in a cell wall defect. Cov txheej txheem no txawv ntawm qhov ntawm - lactam tshuaj tua kab mob, uas ua ntawm transpeptidase theem ntawm cov phab ntsa cell phab ntsa synthesis. Tshuaj lom neeg ntawm Vancomycin tseem muaj kev cuam tshuam hauv:
Broad -} Cov kab mob {{artoccus pneathotria), thiab kuj muaj zog tiv thaiv Anaerobic kab mob xws li Clostridium difficile.
Ntau - phiaj ua: ntxiv rau inhibitive cell phab ntsa, nws tseem tuaj yeem hloov cov kab mob ntawm cov kab mob cell
Tsawg tshuaj yeeb tshuaj: Vim nws cov kev ua yeeb yam ntawm kev nqis tes ua, nws tsis muaj tus ntoo khaub thuas {}} {{1} {} {tsis tshua muaj tsawg.
Tshuaj Zoo rau Kev Thov Hauv Hauv Cheeb Tsam
Lub ntsiab lus vancomycin hmoov yog thov ncaj qha rau lub qhov txhab lossis sab hauv kev cog lus sab hauv thaum kev cuam tshuam nrog kev phiv los ntawm kev noj tshuaj hauv lub cev. Nws cov tshuaj lom neeg ua si lub luag haujlwm tseem ceeb hauv cov txheej txheem no:
Kev tso tawm sai: Daim foos hmoov tuaj yeem ua tau sai npaum li cas ntawm cov nqaij hauv kua, tsim lub siab {}}}} pa ib puag ncig thiab tua cov kab mob ncaj qha.
Ntev -} Lighting txheej txheem ntawm lub qhov txhab ntawm lub sijhawm, ntev dua cov tshuaj tua kab mob, tshwj xeeb yog tsim nyog rau lub sijhawm nrog kev mob siab posterative.
Txo qhov teeb meem raug txo: cov ntaub ntawv thov cov ntshav hauv zos muaj cov ntshav siab tsis muaj ntshav, zam kev phiv los ntawm cov ototoxicity thiab neprotoxicity.
Kev Nyab Xeeb thiab Kev Lom Zem
Cov tshuaj lom ntawm Vancomycin hmoov yog feem ntau cuam tshuam nrog glycosylated ib feem hauv nws cov qauv tshuaj. Thaum siv nyob hauv zos, cov ntsiab lus hauv qab no yuav tsum tau sau tseg hauv qab no:
Cov kev tswj hwm cov kev tswj hwm: ntau dhau kev nce siab yuav ua rau muaj kev txob ntswg. Txawm li cas los xij, cov kev tshawb nrhiav tau pom tias thov 1g ntawm cov hmoov ncaj qha rau lub qhov txhab tsis ua rau muaj kev cuam tshuam loj.
Kev ua xua kev pheej hmoo: tsawg tsawg ntawm cov neeg mob yuav ua xua rau vancomycin, qhia nrog pob khaus thiab khaus. Nws yog ib qho tsim nyog los nug txog kev fab tshuaj li cas ua ntej thov.
Cov neeg tshwj xeeb: cev xeeb tub thiab lactating poj niam yuav tsum siv nws nrog ceev faj. Cov menyuam noj tshuaj noj yuav tsum tau hloov kho raws li lawv qhov hnyav.
Cov kev xav txog cov tshuaj nyob hauv cov ntawv thov kho mob
Hauv kev phais mob orthopedic, cov hmoov Vancomycin hmoov tau tau siv dav dav los tiv thaiv cov kab mob ntsig txog kev cog hniav sab hauv. For example, in open reduction and internal fixation surgeries for tibial plateau fractures, Pilon fractures, and calcaneal fractures, the use of vancomycin powder can reduce the infection rate from 10.6% to 0%. Lub tshuaj lom neeg ruaj khov ntawm cov hmoov yog qhov tseem ceeb hauv cov txheej txheem no: Cov daim hmoov hmoov tuaj yeem tswj hwm tau ob peb teev, txaus npog lub sijhawm phais. Tsis tas li ntawd, Vancomycin kuj tseem tuaj yeem ua ke nrog cov kev xa khoom nanoscale tshiab xws li tooj liab sulfide nanopartics thiab liposomes ntxiv nws cov nyhuv hauv zos.
Cim npe nrov: Txaij Vancomycin Hmoov Cas 1404-90-6, Chaw tsim khoom, chaw tsim khoom, Hoobkas, lag luam Wholesale, yuav, nqe, loj, rau muag