1-pheny phenyl-1,2-propanedione, Molecular Cov Qauv C9H8O2, CAS 57-7, ntawm cov kua kub thiab siab, nws tau piav qhia txog kev muaj butter zib ntab aroma. Cov tshuaj no yog insoluble hauv dej, tab sis soluble hauv ntau cov tshuaj kuab organic, suav nrog cov txheej txheem ntawm cov organic, ua rau nws muaj ib qho kev sib xyaw ua ke nrog ntau daim ntawv thov. Nws yog hydrogen abstraction hom toxicity patkinitiat uas tuaj yeem siv rau hauv cov tshuaj polymerization ntawm cov ntaub ntawv kho hniav. Nyob rau hauv lub teeb tej yam kev mob, cov tshuaj no tuaj yeem ua rau cov ntaub ntawv kho hniav polymerization, yog li ua tiav solidification. Ib qho ntxiv, nws tseem tuaj yeem siv rau kev luam ntawv luam rau cov khoom noj thiab tshuaj, tsis sib thooj los ntawm molecular tsiv teb tsaws. Nws yog ib qho tseem ceeb hauv nruab nrab rau synthesizing complex Heterocyclic teb. Los ntawm cov tshuaj tiv thaiv tshwj xeeb, nws tuaj yeem hloov pauv mus ua cov tshuaj nolecules rau kev kho mob.
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Tshuaj Cov Qauv |
C9H8O2 |
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Muaj pes tsawg leej |
148 |
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Molecular hnyav |
148 |
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m/z |
148 (100.0%), 149 (9.7%) |
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Kev Ntsuam Xyuas |
C, 72.96; H, 5.44; O, 21.60 |
1-pheny phenyl-1,2-propanedione(CAS naj npawb: 579-07-7), tseem hu ua methylphenyfacetophone lossis acetobenzoyl, yog ib hom tshuaj organic, yog cov organic sib xyaw nrog cov qauv tshuaj tshwj xeeb thiab cov khoom. Hauv kev lag luam khoom noj khoom haus, nws yog tshwj xeeb ntau siv los ua cov khoom noj ntxiv thiab theem nrab.
Daim ntawv thov raws li cov khoom noj ntxiv
1. Txhim kho cov zaub mov tsw thiab saj
Nws muaj cov ntxhiab tsw ntxhiab thiab saj, thiab tuaj yeem siv ua khoom noj ntxiv rau txhim kho qhov tsw thiab saj cov zaub mov. Nws tuaj yeem txuas ntxiv rau dej haus, gel, pudding thiab lwm yam zaub mov kom muab rau lawv nplua nuj, yog li kom tau raws li cov neeg siv khoom saj thiab qab.
Cov piv txwv tshwj xeeb: hauv qee hom dej haus, nws yog siv los ua tus neeg sawv cev fleeinging los txhim kho aroma thiab saj ntawm cov dej haus. Cov neeg tau txais kev pab cuam tuaj yeem paub meej txog kev haus dej tsw qab ntawm kev haus dej nrog cov tshuaj ntxiv, ua rau lawv tau sim ntau thiab qab.
2. Txhim Kho Cov Khoom Noj Muaj Zog
Nws kuj tseem tuaj yeem raug ntxiv ua antioxidant lossis stabilizer rau zaub mov kom txhim kho nws cov ruaj khov. Nws tuaj yeem tiv thaiv cov zaub mov ntawm oxidation thiab lwj thaum ua, chaw cia khoom, thiab kev thauj mus los, yog li kev sib txuas lub neej ntawm cov zaub mov.
Cov piv txwv tshwj xeeb: hauv cov khoom ci, nws tuaj yeem siv ua antioxidant los tiv thaiv cov khoom tsis zoo los ntawm roj oxidation. Los ntawm kev ntxiv cov tshuaj no, cov khoom ci tuaj yeem tswj cov xim nrawm dua thiab cov xim sib txuas, thaum txuas ntxiv lawv lub txee lub neej.
Daim Ntawv Thov Raws Li Cov Hluav Taws Xob Nruab Nrab
1. Synthesis ntawm Cov Lus Cog Tseg Heterocclic Compounds
Nws yog ib qho tseem ceeb organic synthemes uas tuaj yeem siv los ua synthesize ntau yam nyuaj siab. Cov no yog cov kev siv heterocclic no muaj ntau cov kev siv hauv kev lag luam khoom noj khoom haus, xws li cov txuj lom, tshuaj tiv thaiv, antioxidants, thiab lwm yam.
Cov piv txwv tshwj xeeb: los ntawm cov tshuaj tiv thaiv tshwj xeeb, nws tuaj yeem hloov pauv mus rau hauv cov txuj lom nrog cov ar specific.... Cov tshuaj xyaw txuj lom no tuaj yeem siv rau cov zaub mov xws li nqaij, nqaij nruab deg, zaub, thiab lwm yam.
2. Khoom cua zaub mov ntxiv
Nws kuj tseem siv tau los ua nruab nrab rau kev sib txuas lwm yam khoom noj ntxiv. Piv txwv li, nws tuaj yeem koom nrog cov khoom siv hluav taws xob, thickeners, emulsifiers, uas muaj ntau cov kev siv hauv kev lag luam khoom noj.
Cov piv txwv tshwj xeeb: hauv cov txheej txheem synthesis, nws koom ua qhov tseem ceeb hauv kev tawm tsam. Los ntawm cov tshuaj tiv thaiv tshwj xeeb, cov tshuaj sib xyaw nrog cov khoom qab zib qab zib tuaj yeem muab cov zaub mov qab zib kom txo cov zaub mov qab zib thaum tswj nws qab zib.
Daim ntawv thov hauv cov khoom noj tshwj xeeb
1. Cov kev lag luam dej haus
Hauv cov dej haus kev lag luam, nws yog tsuas yog siv los ua seasoning thiab aroma ua tau. Nws tuaj yeem nce qib AROMA thiab saj cov dej haus, ua rau lawv raug ntxias thiab qab. Nyob rau tib lub sijhawm, nws kuj tseem tuaj yeem ua tus antioxidant kom tiv thaiv cov dej los ntawm oxidative tsis zoo thaum cia.
Cov piv txwv tshwj xeeb: hauv qee cov pa roj carbon monoxide, nws yog siv ua ib qho ntawm lub caij. Los ntawm synergizing nrog lwm cov dej ntws, dej haus cov pa roj carbon monoxide tuaj yeem ua kom muaj txiaj ntsig nrog cov ntxhiab tsw ntxhiab thiab saj. Ib qho ntxiv, nws kuj tuaj yeem tiv thaiv cov dej haus luam theej rau ntawm kev poob lawv tus thawj aroma thiab saj vim oxidation thaum lub sijhawm khaws cia.
2. Ci Kev Lag Luam
Hauv kev lag luam ci,1-pheny phenyl-1,2-propanedioneyog tsuas yog siv los ua antioxidant thiab qhob cij reprover. Nws tuaj yeem tiv thaiv cov khoom ci los ntawm oxidizing thiab tsis zoo thaum lub sijhawm ua thiab chaw cia khoom, thaum txhim kho cov saj thiab kev ntxhib los mos thiab cov khoom noj.
Cov piv txwv tshwj xeeb: Ntxiv cov khoom tsim nyog ntawm cov tshuaj no thaum lub ncuav ua haujlwm tuaj yeem txuas ntxiv lub txee lub neej ntawm qhob cij thiab txhim kho nws saj. Los ntawm kev tiv thaiv cov roj oxidation thiab tswj cov ruaj khov ntawm cov qauv sab hauv ntawm qhob cij, nws tuaj yeem tswj cov xim ntsuab ntau dua thiab xav tau xim.
3. Nqaij cov khoom lag luam kev lag luam
Hauv kev lag luam nqaij, nws yog tsuas yog siv los ua txuj lom thiab txuag. Nws tuaj yeem nce cov aroma thiab saj cov nqaij, thaum tiv thaiv kev piam sij thiab tsis zoo thaum lub sijhawm cia thiab tsheb thauj mus los.
Cov piv txwv tshwj xeeb: hauv qee cov hnyuv ntxwm thiab cov khoom zoo nkauj, nws tau siv ua ib qho ntawm cov tshuaj ntsuab. Los ntawm synergizing nrog lwm cov txuj lom, cov nqaij cov khoom tuaj yeem ua kom muaj txiaj ntsig nrog cov ntxhiab tsw ntxhiab thiab saj. Lub caij no, nws tseem tuaj yeem ua cov tshuaj tiv thaiv kom ntev ntev rau lub txee lub neej ntawm cov nqaij khoom thiab tiv thaiv kev piam sij los ntawm cov microbial paug.
4. Kev lag luam mis nyuj
Nyob rau hauv kev lag luam mis nyuj, nws yog tsuas yog siv los ua cov flasing tus neeg sawv cev thiab antioxidant. Nws tuaj yeem nce cov aroma thiab saj cov khoom noj khoom haus ntawm cov khoom noj khoom haus, thaum tiv thaiv cov oxidation thiab lwj thaum cia.
Cov piv txwv tshwj xeeb: hauv cov kua nyeem qaub thiab cheese cov khoom lag luam, nws yog siv ua ib qho ntawm cov seasonings. Los ntawm synergizing nrog lwm cov khoom siv mis, cov khoom noj mis nyuj tuaj yeem ua tau zoo nrog cov ntxhiab tsw ntxhiab tsw qab thiab saj. Nyob rau tib lub sijhawm, nws kuj tuaj yeem tiv thaiv cov oxidation thiab tsis zoo ntawm cov rog thiab cov protein hauv cov khoom noj siv mis, yog li kev txuas lub txee lub neej ntawm cov khoom noj khoom haus.
5. Khoom Qab Zib Kev Lag Luam
Nyob rau hauv kev lag luam khoom qab zib, nws yog tsuas yog siv los ua lub qab zib thiab aroma txhim kho. Nws tuaj yeem nce ntxiv cov qab zib thiab aroma nyuaj ntawm cov khoom qab zib, ua rau lawv raug ntxias thiab qab.
Cov piv txwv tshwj xeeb: hauv cov khoom qab zib thiab cov khoom tawv thiab cov khoom noj ntawm Gummy, nws yog siv los ua ib qho khoom qab zib. Los ntawm synergizing nrog lwm cov khoom qab zib, tswm ciab yuav tau txais txiaj ntsig nrog kev nplua nuj qab zib thiab aroma. Nyob rau tib lub sijhawm, nws tseem tuaj yeem ua cov ntxhiab tsw tau nce qib kom muaj AROMA QIB THIAB NYIAM NTAWM CANDIES.
1-pheny phenyl-1,2-propanedioneyog cov kua daj pob tshab siv nyob rau hauv cov synthesis ntawm opioid recept agonists rau cov kab mob plab hnyuv. Nws kuj tseem siv tau rau enantioselective hydrogenation ntawm pyrrolidone ntawm platinum colloids.
Nws yog cais los ntawm cov tub hluas Efedra (Efentra tsev neeg) thiab yog ib tug ua ntej rau Biosynthesis ntawm Ephenrine alkaloids. Kab lus no siv phenylacetone raws li pib cov khoom thiab reacts nrog ethyl nitrite nyob rau hauv qhov kev txiav txim ntawm hydrogen chloride kom tau txais nruab nrab 1-phenyronedione-2-oxime; 1-pheny phenyl-1,2-este anterione-2-oxime yog hydrolyzed hauv kev sib xyaw ntawm formaldehyde, hydrochloric acid, thiab ethanol kom tau txais 1-phenyr-1,2-propynedione.
Kev sim ua haujlwm:
(1) Hauv 2000 liter cov kev tawm tsam lub raj, 800 kg ntawm ethanol thiab 400 kg ntawm phenylacetone tau ntxiv. Nyob rau hauv dej khov dej txias, 78 kg ntawm qhuav hydrogen chloride cov roj tau qhia, thiab 242 kg ntawm ethyl nitrite tau qhia thaum tswj qhov kub ntawm 30-35 degree. Tom qab ua tiav, cov kev tawm tsam tau txuas ntxiv rau qhov kub no rau 2 teev, nres, thiab Ethanc tau yaj tag nrho cov khoom lag luam. Ntxiv 700kg ntawm toluene rau recrystallization kom tau txais 310kg ntawm 1-phenyl1,2-propanedione-2-oxime nrog ib tug tawm ntawm 63.8%.
(2) Hauv 1000 litre cov hlab ntsha, 200kg ntawm formrochloric acid, 200kg ntawm formaldehyde a ethaous kua, thiab 200kg ntawm ethanol tau ntxiv. Nyob rau hauv dej khov dej txias, 200kg ntawm 1-phenyl-1,2-propynedione-2-oxime tau ntxiv rau hauv cov batches ntawm qhov kub hauv qab 15 degrees. Ib qho ntxiv txheej txheem yog exothermic explothermic. Tom qab ntxiv, cov tshuaj tiv thaiv tau muab rau ntawm chav tsev kub rau 2000kg ntawm dichhloromethane, thiab tom qab ntawd tsis muaj ntsev bicarbonate thiab dej kom tshem tawm dichloromshane. Cov khoom nyoos 1-phenyl-1,2-propynedione tau tau {{} kg ntawm lub tshuab nqus dej 1-{-propy distillation, nrog ib tug tawm ntawm 73.5%.
1-phenyl-1,2-propanedione (1-phenyl-1,2-propandione (Case propandione, cas tsis}. 579-07-7) yog ib qho tseem ceeb organic sib xyaw. Nws qhov kev tshawb pom thiab kev tshawb fawb yog ze ze rau kev txhim kho cov organic chemistry. Cov lus qhia hauv qab no nws qhov pom pom dhau los ntawm plaub theem kev tshawb nrhiav, kev txiav txim siab ua haujlwm zoo, thiab kev tshawb fawb niaj hnub ua haujlwm.
Qhov kev tshawb nrhiav ntawm 1-phenyl-1,2-propanedione tuaj yeem raug taug qab mus rau kev tshawb fawb rov qab rau cov khoom ntuj thaum ntxov xyoo pua 19th. Lub sijhawm ntawd, cov kws tshawb fawb cais ntau yam sib txuas nrog cov khoom sib txuas los ntawm cov nroj tsuag, thiab qee cov tshuaj no muaj cov qauv muaj cov qauv sib txuas. Piv txwv li, Cheebtsam muaj cov qauv siv benzene thiab cov qauv diketone tau raug kuaj hauv qee cov nroj tsuag metabolites, qhia kom muaj kev tshawb fawb txog kev ua synthesis. Txawm li cas los xij, vim cov kev txwv ntawm kev sib cais thiab kev tshawb fawb cov tswv yim thaum ntxov thiab cov qauv tshwj xeeb ntawm 1-propanedione tseem tsis tau meej.
Kev txiav txim siab txheej txheem: Kev tawg hauv spectroscopy thiab tshuaj lom neeg
Nyob rau hauv nruab nrab-20th caug xyoo, xws li kev txhim kho nrawm nrawm (xws li cov qauv sib nqus inforroscopy, thiab lwm yam), thiab lwm yam), thiab lwm yam), thiab lwm yam), thiab lwm yam), thiab lwm yam) Tus qauv ntawm 1-phenyl-1,2-propanedione tau lees paub los ntawm cov kauj ruam tseem ceeb hauv qab no:
Molecular mis derivation
Los ntawm kev tshawb xyuas theem qhib kev txiav txim siab thiab cov qauv molecular tau txiav txim siab ua kom zoo, nrog txoj haujlwm hnyav.
Ua haujlwm pab pawg cim
Lub nplhaib rau kev ua kom ncab kev ncab kev ua kom ncab ntawm pawg uas tsis zoo (}} Khib)
Kev Kawm Sib Tw
Los ntawm x - ray diffractaction lossis chiral spectroscopy, tso lub hauv paus rau kev tshawb fawb asymmetric.
Kev ua kom zoo ntawm cov txheej txheem synthesis: los ntawm kev kuaj kom tsim khoom
Cov txheej txheem synthesis ntawm 1-propanedione tau undergone kev hloov pauv ntawm qhov ua tsis tau zoo, thiab los ntawm kuaj qhov ntsuas kom muaj zog, thiab faib ua cov theem hauv qab no:
Thaum Ntxov Synthetic Txoj Kev:Thaum ntxov xyoo pua 20, cov kws tshawb fawb npaj 1-phenyl-1,2-propanedione los ntawm oxidizing benzyl ketone. Piv txwv li, siv Selenium Dioxide (SEO₂) raws li oxidant, cov methylet pab pawg hauv Benzyl Getone tau oxidized rau ib pawg carbonyL, tsim cov khoom lag luam carbonyyl, tsim cov khoom lag luam carbony. Txawm li cas los xij, cov qauv no tau muaj tsawg cov txiaj ntsig thiab selenium compound tau muaj tshuaj lom heev, txwv nws daim ntawv thov.
Txhim kho oxidation txoj kev:Nyob rau hauv nruab nrab-20th caug xyoo, cov kws tshawb nrhiav tau tsim cov roj oxidation ntau dua, xws li siv chromic acid (h mango₂) lossis oxidants) li cov txiaj ntsig thiab kev xaiv. Ib qho ntxiv, encalochemical oxidation kuj tseem siv tau rau cov synthesis ntawm no compound no, ua tiav Directional oxidation ntawm benzyl ketone los ntawm kev tswj hwm lub peev xwm electrode.
Catalytic asymmetric synthesis:Thaum ntxov 21 xyoo pua, nrog rau kev txhim kho asymmetric catalantic catalytictic Technetemes ua tiav Asymmetric synthesis ntawm 1-pheny protione. Piv txwv li, siv chiral catalysts (xws li Kina alkaloid derivatives) Kho kom zoo nkauj thiab 0-25 degree-1-phenyrpropane, uas tuaj yeem txuas ntxiv kom tau txais cov khoom lag luam.
Kev Tshawb Fawb Niaj Hnub No: Los ntawm Kev Tshawb Fawb Yooj Yim rau Kev Siv Cov Ntawv Thov Intermiption
Nrog kev nkag siab tob tob txog cov khoom ntawm 1-phenyl-1,2-propanedione, nws daim ntawv thov tau nthuav dav:
Organic synthesis Qib:Raws li ib qho tseem ceeb organic synthemes, 1 - penyl {}}}}}}}}}} 10}} Piv txwv li, nws derivative 1-phenyl-1,2-propanedione-2- (Ot-EthosCariatl oxime) (CASE
Kev tshawb fawb Bioactivity:Cov kev tshawb fawb tau pom tias 1 {{{- pheny pheny}}}}}}}}}} paabsial biologessorial, anti-intermaratories. Piv txwv li, raws li cov metabolite ntawm eukaryotes, nws yog tsim nyob rau hauv cov nroj tsuag metabolic actions thiab koom nrog biosynthesis ua ntej ntawm efeloids.
Cov Ntawv Thov Khoom Siv:Siv nws cov photoluminescence thiab redox cov khoom, 1-protyl-1,2-propanedione yog siv los npaj cov ntaub ntawv ua haujlwm, xws li cov ntaub ntawv yees duab thiab tshuab hluav taws xob.
Cim npe nrov: 1-phenyl-1,2-propanedionion CAS 579-07-7, cov neeg muag khoom, chaw tsim khoom, Hoobkas, yuav, nqe, loj, rau muag